Disseminated gonococcal infection in a Japanese man with complement 7 deficiency with compound heterozygous variants: A case report
Rationale:
Complement deficiency are known to be predisposed to disseminated gonococcal infection (DGI). We herein present a case of DGI involving a Japanese man who latently had a complement 7 deficiency with compound heterozygous variants.
Patient concerns:
A previously healthy 51-year-old Japanese man complained of sudden-onset high fever. Physical examination revealed various skin lesions including red papules on his trunk and extremities, an impetigo-like pustule on left forearm, and tendinitis of his right forefinger.
Diagnosis:
Blood culture testing detected gram-negative cocci, which was confirmed...
Source: Medicine - April 2, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
A comparative review of current topical antibiotics for impetigo
The objective of this review was to provide a comparison of mechanism of action, efficacy and safety of the available topical antibiotics for impetigo.AREAS COVERED: Randomized clinical trials that evaluated the use of topical antibiotics for treatment of impetigo were included. 2,089 studies were initially identified, and 5 randomized clinical trials met the criteria for further analysis.EXPERT OPINION: Topical antibiotics had greater resolution of impetigo in comparison to vehicle in the pivotal clinical trials in which these medications were evaluated. Adverse events were minimal, with the most common adverse event bein...
Source: Expert Opinion on Drug Safety - March 17, 2021 Category: Drugs & Pharmacology Authors: Eugenio Galindo Adelaide A Hebert Source Type: research
