Topical Nanotherapeutics for Treating MRSA-Associated Skin and Soft Tissue Infection (SSTIs)
AAPS PharmSciTech. 2023 Apr 26;24(5):108. doi: 10.1208/s12249-023-02563-2.ABSTRACTThe emergence of methicillin-resistant Staphylococcus aureus (MRSA) imposes a major challenge for the treatment of infectious diseases with existing antibiotics. MRSA associated with superficial skin and soft tissue infections (SSTIs) is one of them, affecting the skin's superficial layers, and it includes impetigo, folliculitis, cellulitis, furuncles, abscesses, surgical site infections, etc. The efficient care of superficial SSTIs caused by MRSA necessitates local administration of antibiotics, because oral antibiotics does not produce the ...
Source: AAPS PharmSciTech - April 26, 2023 Category: Drugs & Pharmacology Authors: Sriravali Karnam Anil B Jindal Charu Agnihotri Bhim Pratap Singh Atish T Paul Source Type: research
Topical Nanotherapeutics for Treating MRSA-Associated Skin and Soft Tissue Infection (SSTIs)
AAPS PharmSciTech. 2023 Apr 26;24(5):108. doi: 10.1208/s12249-023-02563-2.ABSTRACTThe emergence of methicillin-resistant Staphylococcus aureus (MRSA) imposes a major challenge for the treatment of infectious diseases with existing antibiotics. MRSA associated with superficial skin and soft tissue infections (SSTIs) is one of them, affecting the skin's superficial layers, and it includes impetigo, folliculitis, cellulitis, furuncles, abscesses, surgical site infections, etc. The efficient care of superficial SSTIs caused by MRSA necessitates local administration of antibiotics, because oral antibiotics does not produce the ...
Source: AAPS PharmSciTech - April 26, 2023 Category: Drugs & Pharmacology Authors: Sriravali Karnam Anil B Jindal Charu Agnihotri Bhim Pratap Singh Atish T Paul Source Type: research
Topical Nanotherapeutics for Treating MRSA-Associated Skin and Soft Tissue Infection (SSTIs)
AAPS PharmSciTech. 2023 Apr 26;24(5):108. doi: 10.1208/s12249-023-02563-2.ABSTRACTThe emergence of methicillin-resistant Staphylococcus aureus (MRSA) imposes a major challenge for the treatment of infectious diseases with existing antibiotics. MRSA associated with superficial skin and soft tissue infections (SSTIs) is one of them, affecting the skin's superficial layers, and it includes impetigo, folliculitis, cellulitis, furuncles, abscesses, surgical site infections, etc. The efficient care of superficial SSTIs caused by MRSA necessitates local administration of antibiotics, because oral antibiotics does not produce the ...
Source: AAPS PharmSciTech - April 26, 2023 Category: Drugs & Pharmacology Authors: Sriravali Karnam Anil B Jindal Charu Agnihotri Bhim Pratap Singh Atish T Paul Source Type: research
1098 Anti-inflammatory and antibacterial drug delivery nanocarriers for the topical treatment of MRSA-induced systemic and localized infections
S. aureus infection causes several skin diseases, such as impetigo, carbuncles, folliculitis, etc. Irritation and some discomforts are also frequently reported. What ’s worse, the infection sometimes penetrates through the epidermis, causing a necrotic ulcer—ecthyma. These infections are characterized clinically by abrupt tissue destruction, systemic signs of toxicity, and high mortality [Dennis L. Stevens, 2022]. Bacterial skin infections are common in most developing countries [Roderick Hay, 2006]. (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - April 17, 2023 Category: Dermatology Authors: Y. Chang, C. Lin, T. Huang, J. Fang Source Type: research
Bullous impetigo on a young man's abdomen
Dermatol Online J. 2023 Feb 15;29(1). doi: 10.5070/D329160220.ABSTRACTBullous impetigo is a variant of epidermal infection by Staphylococcus aureus, representing 30% of impetigo cases. Its clinical appearance may mimic certain autoimmune blistering dermatoses and other cutaneous infections, sometimes necessitating careful evaluation. Herein we present a patient with bullous impetigo in a striking and characteristic appearance and briefly overview the approach to diagnosis, treatment, and prevention.PMID:37040917 | DOI:10.5070/D329160220 (Source: Dermatol Online J)
Source: Dermatol Online J - April 11, 2023 Category: Dermatology Authors: Peter A Young Melissa C Leeolou Saisindhu Narala Atif Saleem Gordon H Bae Source Type: research
