DEA Delays Proposed Telehealth, Buprenorphine Rules
The U.S. Drug Enforcement Administration (DEA)has delayed finalizing two proposed rules that were set to go into effect after theCOVID-19 public health emergency expires on May 11. The proposed rules, if finalized, would affect how health professionals implement telehealth services and prescribe certain controlled medications, including medications for treating attention-deficit/hyperactivity disorder and opioid use disorder (OUD). The DEA received 38,000 comments in response to the proposed rules, which wereannounced on February 24. Instead of finalizing the rules, the DEA, in concert with the U.S. Department of Health an...
Source: Psychiatr News - May 4, 2023 Category: Psychiatry Tags: Anne Milgram APA controlled substances DEA Department of Health and Human Services Drug Enforcement Administration opioid use disorder telehealth Source Type: research
Diagnosis and Management of Opioid-Induced Esophageal Dysfunction
AbstractPurpose of ReviewThe purpose of this review is to discuss the pathophysiology, clinical presentation, and diagnosis of opioid-induced esophageal dysfunction (OIED) and describe the limited data available on its management.Recent FindingsOIED is defined by chronic opioid use, esophageal symptoms, and specific manometric abnormalities. Larger retrospective studies show that patients with OIED present with significant esophageal symptoms particularly dysphagia. High-resolution esophageal manometry findings in OIED include distal esophageal spasm, esophagogastric junction outflow obstruction, achalasia type III, and hy...
Source: Current Treatment Options in Gastroenterology - April 10, 2023 Category: Gastroenterology Source Type: research
Determinants Of Stable Pain And Long Acting Opioid Use For Chronic Non-Cancer Related Pain Treatment Over 12 Months
Opioids remain an option for patients with chronic pain and inadequate relief from non-opioid medications or non-pharmacological therapies; however, chronic opioid use can lead to opioid use disorder (OUD). Having information to inform a risk ‐benefit judgment about the likelihood of successful chronic opioid treatment would be useful. We re-analyzed individual participant data from 2464 trial participants in eight studies of long acting oxycodone and hydrocodone to develop a prediction model of maintaining stable or improved pain and opioid doses over 12 months following successful titration to an effective dose. (Sourc...
Source: The Journal of Pain - April 1, 2023 Category: Materials Science Authors: John Farrar, Warren B. Bilker, Philip T. Cochetti, Charles E. Argoff, Russell Bell, Jennifer Haythornthwaite, Ian Gilron, Nathaniel P. Katz Source Type: research
APA Responds to DEA ’s Proposed Rules Regarding Telehealth, Buprenorphine
Today APA filed two letters with the U.S. Drug Enforcement Administration (DEA) in response to two proposed rules that if finalized would affect how health professionals implement telehealth services and prescribe certain controlled medications. The proposed rules, which were developed with the U.S. Department of Health and Human Services and in close coordination with the U.S. Department of Veterans Affairs andannounced on February 24, would extend certain flexibilities in these areas after the COVID-19 public health emergency expires on May 11. Yet in several ways the proposed rules are more restrictive than what the pub...
Source: Psychiatr News - March 31, 2023 Category: Psychiatry Tags: APA barriers to care buprenorphine controlled substances costs DEA opioid use disorder proposed rule public health emergency telehealth Source Type: research
Variation in adverse drug events of opioids in the United States
Conclusion: The use of the FAERS with the ARCOS provides insights into dynamic changes in ADEs of the selected opioids in the US. There is further need to monitor and address the ADEs of these drugs. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - March 24, 2023 Category: Drugs & Pharmacology Source Type: research
A Cautionary Tale of Herbal Supplements: What We Have Learned from Kratom
AbstractPurpose of ReviewThis review enumerates seven outbreaks of kratom (Mitragyna speciosa) product adulteration and contamination in the context of the United States Dietary Supplement Health and Education Act (DSHEA).Recent FindingsAt least seven distinct episodes of kratom product contamination or adulteration are known: (1) krypton, a kratom product adulterated with O-desmethyltramadol that resulted in at least nine fatal poisonings; (2) a suspected case of kratom contamination with hydrocodone and morphine; (3) a case of kratom adulteration with phenylethylamine; (4) contamination of multiple kratom products with h...
Source: Current Addiction Reports - February 4, 2023 Category: Addiction Source Type: research
Comparative Study of Opioid Initiation with Tramadol, short-acting Hydrocodone or short-acting Oxycodone on opioid-related Adverse Outcomes Among Chronic non-cancer Pain Subjects
DISCUSSION: Low-dose oxycodone had higher risk of opioid-related adverse outcomes compared to low-dose tramadol and hydrocodone. This should be interpreted in conjunction with the benefits of pain control and functioning associated with oxycodone use in future research.PMID:36728675 | DOI:10.1097/AJP.0000000000001093 (Source: Cancer Control)
Source: Cancer Control - February 2, 2023 Category: Cancer & Oncology Authors: Mahip Acharya Corey J Hayes Chenghui Li Jacob T Painter Lindsey Dayer Bradley C Martin Source Type: research
Follow-Up: Effects of a Pandemic and Isolation on Alcohol and Psychoactive Medication Use in a Population of Rehabilitation and Pain Patients
CONCLUSION: In summary, these findings demonstrate relatively consistent drug use, with decreased positivity for high-risk drugs and dangerous drug combinations. We speculate that monitoring of these patients mitigates the possibility of drug misuse and potential overdose and is in concordance with the goals of these monitoring programs.PMID:36564077 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - December 23, 2022 Category: Laboratory Medicine Authors: Amadeo Pesce Raymond T Suhandynata Dennis Ritz Richard Thomas Gregory Ackerman Katie Bollman Source Type: research
Follow-Up: Effects of a Pandemic and Isolation on Alcohol and Psychoactive Medication Use in a Population of Rehabilitation and Pain Patients
CONCLUSION: In summary, these findings demonstrate relatively consistent drug use, with decreased positivity for high-risk drugs and dangerous drug combinations. We speculate that monitoring of these patients mitigates the possibility of drug misuse and potential overdose and is in concordance with the goals of these monitoring programs.PMID:36564077 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - December 23, 2022 Category: Laboratory Medicine Authors: Amadeo Pesce Raymond T Suhandynata Dennis Ritz Richard Thomas Gregory Ackerman Katie Bollman Source Type: research
