Impact of the COVID-19 Pandemic on Diagnosis and Management of Gynecological Cancer: A Single-Center Analysis
Conclusions: The COVID-19 pandemic had a significant impact on the diagnosis and management of most gynecological malignancies, namely, on time to first treatment, chosen oncological therapies and surgical approaches. These results suggest important clinical and healthcare implications that should be addressed in future prospective studies.PMID:36557063 | PMC:PMC9787860 | DOI:10.3390/medicina58121862 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - December 23, 2022 Category: Universities & Medical Training Authors: Dora Antunes Lisandra Mendon ça Ângela Melo S ónia Gonçalves Francisco Nogueira Martins Nuno Nogueira Martins Source Type: research
Impact of the COVID-19 Pandemic on Diagnosis and Management of Gynecological Cancer: A Single-Center Analysis
Conclusions: The COVID-19 pandemic had a significant impact on the diagnosis and management of most gynecological malignancies, namely, on time to first treatment, chosen oncological therapies and surgical approaches. These results suggest important clinical and healthcare implications that should be addressed in future prospective studies.PMID:36557063 | PMC:PMC9787860 | DOI:10.3390/medicina58121862 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - December 23, 2022 Category: Universities & Medical Training Authors: Dora Antunes Lisandra Mendon ça Ângela Melo S ónia Gonçalves Francisco Nogueira Martins Nuno Nogueira Martins Source Type: research
Impact of the COVID-19 Pandemic on Diagnosis and Management of Gynecological Cancer: A Single-Center Analysis
Conclusions: The COVID-19 pandemic had a significant impact on the diagnosis and management of most gynecological malignancies, namely, on time to first treatment, chosen oncological therapies and surgical approaches. These results suggest important clinical and healthcare implications that should be addressed in future prospective studies.PMID:36557063 | PMC:PMC9787860 | DOI:10.3390/medicina58121862 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - December 23, 2022 Category: Universities & Medical Training Authors: Dora Antunes Lisandra Mendon ça Ângela Melo S ónia Gonçalves Francisco Nogueira Martins Nuno Nogueira Martins Source Type: research
Impact of the COVID-19 Pandemic on Diagnosis and Management of Gynecological Cancer: A Single-Center Analysis
Conclusions: The COVID-19 pandemic had a significant impact on the diagnosis and management of most gynecological malignancies, namely, on time to first treatment, chosen oncological therapies and surgical approaches. These results suggest important clinical and healthcare implications that should be addressed in future prospective studies.PMID:36557063 | PMC:PMC9787860 | DOI:10.3390/medicina58121862 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - December 23, 2022 Category: Universities & Medical Training Authors: Dora Antunes Lisandra Mendon ça Ângela Melo S ónia Gonçalves Francisco Nogueira Martins Nuno Nogueira Martins Source Type: research
Impact of the COVID-19 Pandemic on Diagnosis and Management of Gynecological Cancer: A Single-Center Analysis
Conclusions: The COVID-19 pandemic had a significant impact on the diagnosis and management of most gynecological malignancies, namely, on time to first treatment, chosen oncological therapies and surgical approaches. These results suggest important clinical and healthcare implications that should be addressed in future prospective studies.PMID:36557063 | PMC:PMC9787860 | DOI:10.3390/medicina58121862 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - December 23, 2022 Category: Universities & Medical Training Authors: Dora Antunes Lisandra Mendon ça Ângela Melo S ónia Gonçalves Francisco Nogueira Martins Nuno Nogueira Martins Source Type: research
Impact of the COVID-19 Pandemic on Diagnosis and Management of Gynecological Cancer: A Single-Center Analysis
Conclusions: The COVID-19 pandemic had a significant impact on the diagnosis and management of most gynecological malignancies, namely, on time to first treatment, chosen oncological therapies and surgical approaches. These results suggest important clinical and healthcare implications that should be addressed in future prospective studies.PMID:36557063 | PMC:PMC9787860 | DOI:10.3390/medicina58121862 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - December 23, 2022 Category: Universities & Medical Training Authors: Dora Antunes Lisandra Mendon ça Ângela Melo S ónia Gonçalves Francisco Nogueira Martins Nuno Nogueira Martins Source Type: research
Case report: Conservative treatment for fertility preservation in a woman with hemoperitoneum due to an invasive mole
ConclusionOur experience highlights the potential feasibility and efficacy of conservative treatment for fertility preservation in such scenarios. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - December 6, 2022 Category: Cancer & Oncology Source Type: research
Claudin-6 enhances the malignant progression of gestational trophoblastic neoplasm by promoting proliferation and metastasis
ConclusionWe propose that CLDN6 participates in the development of GTD and may become a new therapeutic target for CC. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - December 5, 2022 Category: Cancer & Oncology Source Type: research
Current chemotherapeutic options for the treatment of gestational trophoblastic disease
Expert Opin Pharmacother. 2022 Nov 18. doi: 10.1080/14656566.2022.2150075. Online ahead of print.ABSTRACTINTRODUCTION: Gestational trophoblastic neoplasia (GTN) is a rare tumor that arises from trophoblastic tissues with high remission rates after chemotherapy treatment. GTN can develop from any gestational event, such as miscarriage, ectopic pregnancy and preterm/term pregnancy, but being more frequent after hydatidiform mole. The sensitivity of this tumor to chemotherapy and the presence of an exceptional tumor marker allow high remission rates, especially when patients are treated in referral centers.Areas covered. Obse...
Source: Expert Opinion on Pharmacotherapy - November 18, 2022 Category: Drugs & Pharmacology Authors: Antonio Braga Gabriela Paiva Cassia Juliana Cattai Kevin M Elias Neil S Horowitz Ross S Berkowitz Source Type: research
Cancers, Vol. 14, Pages 5563: Placental Mesenchymal Dysplasia and Beckwith & ndash;Wiedemann Syndrome
Cancers, Vol. 14, Pages 5563: Placental Mesenchymal Dysplasia and Beckwith–Wiedemann Syndrome
Cancers doi: 10.3390/cancers14225563
Authors:
Hidenobu Soejima
Satoshi Hara
Takashi Ohba
Ken Higashimoto
Placental mesenchymal dysplasia (PMD) is characterized by placentomegaly, aneurysmally dilated chorionic plate vessels, thrombosis of the dilated vessels, and large grapelike vesicles, and is often mistaken for partial or complete hydatidiform mole with a coexisting normal fetus. Androgenetic/biparental mosaicism (ABM) has been found in many PMD cases. Beckwith–Wiedemann syndrome (BWS) is a...
Source: Cancers - November 12, 2022 Category: Cancer & Oncology Authors: Hidenobu Soejima Satoshi Hara Takashi Ohba Ken Higashimoto Tags: Review Source Type: research
Retinoids in cancer chemoprevention and therapy: Meta-analysis of randomized controlled trials
In conclusion, clinical application of retinoids was associated with reduction in disease recurrence and improvement in clinical response, illustrating that retinoids play a key role in cancer prevention and therapy. Further research is needed to broaden the utility of retinoids in other types of cancers.Systematic Review Registration: PROSPERO, identifier CRD42022296706. (Source: Frontiers in Genetics)
Source: Frontiers in Genetics - November 9, 2022 Category: Genetics & Stem Cells Source Type: research
Regulatory Effects of Fyn on Trophoblast Cell Behaviors and Function
Biomed Res Int. 2022 Oct 25;2022:6006981. doi: 10.1155/2022/6006981. eCollection 2022.ABSTRACTFyn has been proven to be involved in various cell behaviors and pathophysiological processes. However, the expression and roles of Fyn in trophoblasts remain unclear. Here, we aimed to evaluate the participation of Fyn in trophoblast behavior and function, and the related mechanisms were briefly explored. Fyn expression in the HTR-8/SVneo, JEG-3, and JAR cell lines was evaluated by immunofluorescence, quantitative real-time PCR and western blotting. Fyn expression in human hydatidiform moles was also determined by immunohistochem...
Source: Cell Research - November 4, 2022 Category: Cytology Authors: Qian Liu Jinli Ding Qingzhen Xie Source Type: research
Regulatory Effects of Fyn on Trophoblast Cell Behaviors and Function
Biomed Res Int. 2022 Oct 25;2022:6006981. doi: 10.1155/2022/6006981. eCollection 2022.ABSTRACTFyn has been proven to be involved in various cell behaviors and pathophysiological processes. However, the expression and roles of Fyn in trophoblasts remain unclear. Here, we aimed to evaluate the participation of Fyn in trophoblast behavior and function, and the related mechanisms were briefly explored. Fyn expression in the HTR-8/SVneo, JEG-3, and JAR cell lines was evaluated by immunofluorescence, quantitative real-time PCR and western blotting. Fyn expression in human hydatidiform moles was also determined by immunohistochem...
Source: Biomed Res - November 4, 2022 Category: Research Authors: Qian Liu Jinli Ding Qingzhen Xie Source Type: research
