Rapid progression from complete molar pregnancy to post-molar gestational trophoblastic neoplasia: a rare case report and literature review
ConclusionIn rare cases, CMH can rapidly progress into pGTN. Imaging in combination with hCG surveillance seems to play a vital role guiding timely diagnosis and treatment in the specific condition. Low-risk gestational trophoblastic neoplasia (GTN) should be managed stratified according to the individual situation. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - December 15, 2023 Category: Cancer & Oncology Source Type: research

Intraplacental Gestational Neoplasms: A Review of Clinically Relevant Diagnostically Challenging Lesions
CONCLUSIONS.—: Intraplacental gestational tumors exist along the spectrum of benign (chorangioma) to aggressive malignant (choriocarcinoma) neoplasms with a high potential for metastasis. Although most gestational choriocarcinomas follow complete hydatidiform mole, 20% to 25% occur in association with normal intrauterine gestations, including rare cases in which they are detected within the placenta (IPC). IPCs range from asymptomatic to widely metastatic, with metastases possible even when only microscopic IPCs are present. A second, even less common lesion, variably called "chorangiocarcinoma" and chorangioma with atyp...
Source: Archives of Pathology and Laboratory Medicine - November 17, 2023 Category: Laboratory Medicine Authors: Julia Dahl Source Type: research

Intraplacental Gestational Neoplasms: A Review of Clinically Relevant Diagnostically Challenging Lesions
CONCLUSIONS.—: Intraplacental gestational tumors exist along the spectrum of benign (chorangioma) to aggressive malignant (choriocarcinoma) neoplasms with a high potential for metastasis. Although most gestational choriocarcinomas follow complete hydatidiform mole, 20% to 25% occur in association with normal intrauterine gestations, including rare cases in which they are detected within the placenta (IPC). IPCs range from asymptomatic to widely metastatic, with metastases possible even when only microscopic IPCs are present. A second, even less common lesion, variably called "chorangiocarcinoma" and chorangioma with atyp...
Source: Archives of Pathology and Laboratory Medicine - November 17, 2023 Category: Laboratory Medicine Authors: Julia Dahl Source Type: research

Intraplacental Gestational Neoplasms: A Review of Clinically Relevant Diagnostically Challenging Lesions
CONCLUSIONS.—: Intraplacental gestational tumors exist along the spectrum of benign (chorangioma) to aggressive malignant (choriocarcinoma) neoplasms with a high potential for metastasis. Although most gestational choriocarcinomas follow complete hydatidiform mole, 20% to 25% occur in association with normal intrauterine gestations, including rare cases in which they are detected within the placenta (IPC). IPCs range from asymptomatic to widely metastatic, with metastases possible even when only microscopic IPCs are present. A second, even less common lesion, variably called "chorangiocarcinoma" and chorangioma with atyp...
Source: Archives of Pathology and Laboratory Medicine - November 17, 2023 Category: Laboratory Medicine Authors: Julia Dahl Source Type: research

Intraplacental Gestational Neoplasms: A Review of Clinically Relevant Diagnostically Challenging Lesions
CONCLUSIONS.—: Intraplacental gestational tumors exist along the spectrum of benign (chorangioma) to aggressive malignant (choriocarcinoma) neoplasms with a high potential for metastasis. Although most gestational choriocarcinomas follow complete hydatidiform mole, 20% to 25% occur in association with normal intrauterine gestations, including rare cases in which they are detected within the placenta (IPC). IPCs range from asymptomatic to widely metastatic, with metastases possible even when only microscopic IPCs are present. A second, even less common lesion, variably called "chorangiocarcinoma" and chorangioma with atyp...
Source: Archives of Pathology and Laboratory Medicine - November 17, 2023 Category: Laboratory Medicine Authors: Julia Dahl Source Type: research

Intraplacental Gestational Neoplasms: A Review of Clinically Relevant Diagnostically Challenging Lesions
CONCLUSIONS.—: Intraplacental gestational tumors exist along the spectrum of benign (chorangioma) to aggressive malignant (choriocarcinoma) neoplasms with a high potential for metastasis. Although most gestational choriocarcinomas follow complete hydatidiform mole, 20% to 25% occur in association with normal intrauterine gestations, including rare cases in which they are detected within the placenta (IPC). IPCs range from asymptomatic to widely metastatic, with metastases possible even when only microscopic IPCs are present. A second, even less common lesion, variably called "chorangiocarcinoma" and chorangioma with atyp...
Source: Archives of Pathology and Laboratory Medicine - November 17, 2023 Category: Laboratory Medicine Authors: Julia Dahl Source Type: research

Intraplacental Gestational Neoplasms: A Review of Clinically Relevant Diagnostically Challenging Lesions
CONCLUSIONS.—: Intraplacental gestational tumors exist along the spectrum of benign (chorangioma) to aggressive malignant (choriocarcinoma) neoplasms with a high potential for metastasis. Although most gestational choriocarcinomas follow complete hydatidiform mole, 20% to 25% occur in association with normal intrauterine gestations, including rare cases in which they are detected within the placenta (IPC). IPCs range from asymptomatic to widely metastatic, with metastases possible even when only microscopic IPCs are present. A second, even less common lesion, variably called "chorangiocarcinoma" and chorangioma with atyp...
Source: Archives of Pathology and Laboratory Medicine - November 17, 2023 Category: Laboratory Medicine Authors: Julia Dahl Source Type: research

Intraplacental Gestational Neoplasms: A Review of Clinically Relevant Diagnostically Challenging Lesions
CONCLUSIONS.—: Intraplacental gestational tumors exist along the spectrum of benign (chorangioma) to aggressive malignant (choriocarcinoma) neoplasms with a high potential for metastasis. Although most gestational choriocarcinomas follow complete hydatidiform mole, 20% to 25% occur in association with normal intrauterine gestations, including rare cases in which they are detected within the placenta (IPC). IPCs range from asymptomatic to widely metastatic, with metastases possible even when only microscopic IPCs are present. A second, even less common lesion, variably called "chorangiocarcinoma" and chorangioma with atyp...
Source: Archives of Pathology and Laboratory Medicine - November 17, 2023 Category: Laboratory Medicine Authors: Julia Dahl Source Type: research

Intraplacental Gestational Neoplasms: A Review of Clinically Relevant Diagnostically Challenging Lesions
CONCLUSIONS.—: Intraplacental gestational tumors exist along the spectrum of benign (chorangioma) to aggressive malignant (choriocarcinoma) neoplasms with a high potential for metastasis. Although most gestational choriocarcinomas follow complete hydatidiform mole, 20% to 25% occur in association with normal intrauterine gestations, including rare cases in which they are detected within the placenta (IPC). IPCs range from asymptomatic to widely metastatic, with metastases possible even when only microscopic IPCs are present. A second, even less common lesion, variably called "chorangiocarcinoma" and chorangioma with atyp...
Source: Archives of Pathology and Laboratory Medicine - November 17, 2023 Category: Laboratory Medicine Authors: Julia Dahl Source Type: research

Cornual invasive hydatidiform mole: a rare case report and literature review
The cornual pregnancy is a rare condition of ectopic pregnancies. Invasive hydatidiform mole is a rare form of gestational trophoblastic diseases. Cornual invasive hydatidiform mole is extremely rare. (Source: BMC Women's Health)
Source: BMC Women's Health - November 2, 2023 Category: OBGYN Authors: Jing Qian, Song Xu and Li Chen Tags: Case Report Source Type: research

Double Trisomy 16 and 22 Clinically Mimic Partial Hydatidiform Mole in a Case of Subsequent Pregnancy Loss
In conclusion, aneuploidies can mimic partial hydatidiform mole. Genetic analysis is helpful on the one hand to rule out partial hydatidiform mole and on the other hand to identify aneuploidies and in this way to determine the cause of miscarriage.PMID:37888974 (Source: Physiological Research)
Source: Physiological Research - October 27, 2023 Category: Physiology Authors: L Gergely M Korbe ľ A Adamec V Repisk á P Bab ál K Meli šová P Pri ščáková Source Type: research