Urine high-risk human papillomavirus testing as an alternative to routine cervical screening: A comparative diagnostic accuracy study of two urine collection devices using a randomised study design trial
CONCLUSIONS: Testing of FVU-device-collected urine for HPV was superior to standard-pot-collected urine in colposcopy attendees and has promising sensitivity for CIN2+ detection. General population HPV testing of FVU-device-collected urine will establish its clinical performance and acceptability as an alternative to routine cervical screening.PMID:38660737 | DOI:10.1111/1471-0528.17831 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 25, 2024 Category: OBGYN Authors: Jennifer C Davies Alexandra Sargent Elisabeth Pinggera Suzanne Carter Clare Gilham Peter Sasieni Emma J Crosbie Source Type: research
Viruses, Vol. 16, Pages 667: Unveiling the Role of Human Papillomavirus in Urogenital Carcinogenesis a Comprehensive Review
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Human papillomavirus (HPV), an oncogenic DNA virus, is the most common sexually transmitted virus and significant public health concern globally. Despite the substantial prevalence of HPV infection among men, routine testing remains elusive due to the lack of approved HPV tests and the complexity of detection methods. Various studies have explored the link between HPV and genitourinary cancers, revealing different associations influenced by geographic variation, histological subtype and methodological differences. These findings underscore the importance of further research to elucidate the role of HPV in male urogen...
Source: Viruses - April 25, 2024 Category: Virology Authors: Beliz Bahar Karao ğlan Y üksel Ürün Tags: Review Source Type: research
Cancers, Vol. 16, Pages 1629: Serum Proteomic Signatures in Cervical Cancer: Current Status and Future Directions
We report on identified multimarker panels of serum proteomic studies in CC for the past 5 years, the potential for modern computational biology efforts, and the utilization of nationwide biobanks to bridge the gap between multivariate protein signature development and the prediction of clinically relevant CC patient outcomes. (Source: Cancers)
Source: Cancers - April 24, 2024 Category: Cancer & Oncology Authors: Chaston Weaver Alisha Nam Caitlin Settle Madelyn Overton Maya Giddens Katherine P. Richardson Rachael Piver David P. Mysona Bunja Rungruang Sharad Ghamande Richard McIndoe Sharad Purohit Tags: Review Source Type: research
Nonlinear relationship between viral load and TCT in single/multiple HPV52 infection
To determine the correlation between HPV (human papillomavirus) 52 viral load, multiple infections and ThinPrep cytology test (TCT), to inform clinical management of HPV52-positive women after cervical cancer ... (Source: Virology Journal)
Source: Virology Journal - April 23, 2024 Category: Virology Authors: Bingbing Ma, Jie Zhou, Weijuan Zhou, Zhanzhong Ma, Juan Chen and Hongbo Hu Tags: Research Source Type: research
Cancers, Vol. 16, Pages 1610: Imiquimod Is Effective in Reducing Cervical Intraepithelial Neoplasia: A Systematic Review and Meta-Analysis
Conclusions: Our findings indicate that topical Imiquimod is safe and effective in reducing cervical intraepithelial neoplasia and promoting HPV clearance. However, it was found to be inferior compared to conization. Imiquimod could be considered a potential medication for high-grade CIN patients and should be incorporated into guidelines for treating cervical dysplasia. (Source: Cancers)
Source: Cancers - April 22, 2024 Category: Cancer & Oncology Authors: Bal ázs Hamar Brigitta Teutsch Eszter Hoffmann P éter Hegyi Andrea Harnos P éter Nyirády Zsombor Hunka N ándor Ács Ferenc B ánhidy Zsolt Melczer Tags: Systematic Review Source Type: research
Acceptability of self-collected vaginal samples for human papillomavirus testing for primary cervical cancer screening: comparison of face-to-face and online recruitment modes
This study aimed to assess the acceptability and attitudes of women towards human papillomavirus (HPV) self-sampling and compare the effectiveness of two delivery modes utilising face-to-face and online websit... (Source: BMC Public Health)
Source: BMC Public Health - April 22, 2024 Category: Consumer Health News Authors: Siew-Fei Ngu, Lesley SK Lau, Ching Yin Chan, Hextan YS Ngan, Annie NY Cheung and Karen KL Chan Tags: Research Source Type: research
Analysis of atypical glandular cells in ThinPrep Pap smear and follow-up histopathology
CONCLUSION: The AGC diagnostic rate at our institution falls within the range given by the College of American Pathologists. A significant number of cases had follow-up histologic results available, and the overall 5-year insignificant AGC rate was 0.12%.PMID:38628324 | PMC:PMC11018051 | DOI:10.1080/08998280.2024.2324656 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Tengfei Wang Yinan Hua Lina Liu Bing Leng Source Type: research
Analysis of atypical glandular cells in ThinPrep Pap smear and follow-up histopathology
CONCLUSION: The AGC diagnostic rate at our institution falls within the range given by the College of American Pathologists. A significant number of cases had follow-up histologic results available, and the overall 5-year insignificant AGC rate was 0.12%.PMID:38628324 | PMC:PMC11018051 | DOI:10.1080/08998280.2024.2324656 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Tengfei Wang Yinan Hua Lina Liu Bing Leng Source Type: research
Analysis of atypical glandular cells in ThinPrep Pap smear and follow-up histopathology
CONCLUSION: The AGC diagnostic rate at our institution falls within the range given by the College of American Pathologists. A significant number of cases had follow-up histologic results available, and the overall 5-year insignificant AGC rate was 0.12%.PMID:38628324 | PMC:PMC11018051 | DOI:10.1080/08998280.2024.2324656 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Tengfei Wang Yinan Hua Lina Liu Bing Leng Source Type: research
Awareness, knowledge and attitudes of human papillomavirus infection, screening and vaccination: a survey study in Greece
ConclusionOur results indicate that although awareness of the existence of HPV infection is high in Greek general population, the actual perception of the pathophysiology of transmission and importance of HPV testing and vaccination is low. Targeting specific population groups is essential to help increase HPV coverage and screening. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 16, 2024 Category: OBGYN Source Type: research
Predictable changes in the accuracy of human papillomavirus tests after vaccination: review with implications for performance monitoring in cervical screening
British Journal of Cancer, Published online: 13 April 2024; doi:10.1038/s41416-024-02681-zPredictable changes in the accuracy of human papillomavirus tests after vaccination: review with implications for performance monitoring in cervical screening (Source: British Journal of Cancer)
Source: British Journal of Cancer - April 13, 2024 Category: Cancer & Oncology Authors: Matejka Rebolj Adam R. Brentnall Kate Cuschieri Source Type: research
Impact of high-performance HPV testing to improve cervical cancer screening in China: A prospective population-based multicenter cohort study
CONCLUSIONS: The study has indicated that HBRT-14 has a reliable clinical performance for use in cervical screening. The validated HPV test would improve the quality of population screening.PMID:38599463 | DOI:10.1016/j.cmi.2024.03.035 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Jian Yin Shaokai Zhang Zhifang Li Yufei Li Hong Wang Xun Zhang Qinjing Pan Wen Chen Xiping Luo Xibin Sun Fanghui Zhao Youlin Qiao Source Type: research
Epidemiology of human papillomavirus infection in women from Xiamen, China, 2013 to 2023
CONCLUSION: The study provided the largest scale information on the recent epidemiological characteristics of HPV infection in Xiamen, and even in Fujian Province, China, which would support making the prevention and control strategies for cervical cancer in the region.PMID:38590815 | PMC:PMC11000419 | DOI:10.3389/fpubh.2024.1332696 (Source: Cancer Control)
Source: Cancer Control - April 9, 2024 Category: Cancer & Oncology Authors: Xingmei Yao Qing Li Yu Chen Zhuowen Du Yanru Huang Yixi Zhou Jian Zhang Wenbo Wang Lutan Zhang Jieqiong Xie Chao Xu Yunsheng Ge Yulin Zhou Source Type: research
HPV-Related Multiphenotypic Sinonasal Carcinoma: A Clinicoradiological Series of 3 Cases With Full Endoscopic Surgical Outcome
Conclusion and Relevance: HMSC represents a newly identified diagnosis that constitutes a significant challenge for both clinicians and pathologists. It is crucial to acknowledge its indolent clinical course and the apparent contradiction between aggressive radiological features and the noninvasive nature of surgical findings. Skull base surgeons should be aware that, despite these complexities, endoscopic treatment is achievable in the majority of cases. This understanding is essential for the effective management of HMSC.PMID:38591784 | DOI:10.1177/01455613241247729 (Source: Ear, Nose and Throat Journal)
Source: Ear, Nose and Throat Journal - April 9, 2024 Category: ENT & OMF Authors: Catherine Beaumont Sylvie Nadeau Pierre-Olivier Champagne Michel Beauchemin No émie Villemure-Poliquin Source Type: research
