Utility of PET-CT in Newly Diagnosed HPV-Associated Oropharyngeal Squamous Cell Carcinoma
CONCLUSION: In uncomplicated HPV-associated OPSCC, CT offers equivalent diagnostic accuracy to that of combined whole-body PET-CT for clinical staging, and has no appreciable impact on treatment selection. A reduced reliance on routine PET-CT during initial workup of HPV-associated OPSCC may be favorable for otherwise healthy patients with clinically evident sites of primary disease.PMID:36453776 | DOI:10.1177/00034894221135934 (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - December 1, 2022 Category: ENT & OMF Authors: Jaclyn Lee Seth J Davis Shaunak N Amin Sarah L Rohde Young J Kim Source Type: research

Vaccination against human papillomavirus in Brazilian schoolchildren: National Survey of School Health, 2019
CONCLUSION: one out of every two Brazilian schoolchildren was vaccinated against HPV. Misinformation was a recurring reason for non-vaccination. The North and Northeast regions had the highest prevalence of non-vaccinated people, observed mainly in adolescents from public schools.HIGHLIGHTS: (1) 63% of Brazilian schoolchildren reported having been vaccinated against human papillomavirus (HPV).(2) In Brazil, in 2019, the prevalence of immunized girls was higher than that of boys.(3) Misinformation and fear are reasons for hesitating vaccination.(4) Social and health inequalities may reflect upon HPV vaccination.(5) Achievin...
Source: Revista Latino-Americana de Enfermagem - November 30, 2022 Category: Nursing Authors: Isabella de Alc ântara Gomes Silva Ana Carolina Micheletti Gomide Nogueira de S á Elton Junio Sady Prates Deborah Carvalho Malta Fernanda Penido Matozinhos T ércia Moreira Ribeiro da Silva Source Type: research

Predictive Value of Anti- E6 Oncoprotein (High Risk- Human Papilloma Virus) and p16 Ink4a for Detecting HPV in Oral Epithelial Dysplasia
CONCLUSION: There was an association between HPV and OPMD. Both biomarker tests, HPV E6 and p16 immunocytochemistry had a specific role in the detection of HR-HPV. Anti-E6 immunocytochemistry can be a valuable test with higher specificity for HPV DNA detection in oral epithelial dysplasia without losing sensitivity.PMID:36444605 | DOI:10.31557/APJCP.2022.23.11.3915 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - November 29, 2022 Category: Cancer & Oncology Authors: Gowthami Jawahar Gururaj Narayana Rao Beryl Rachel J Angeline J Nandhinipriya B Swetha S Source Type: research

Vitamin D Receptor Gene Polymorphisms and the Risk of CIN2+ in Shanxi Population
Biomed Res Int. 2022 Nov 16;2022:6875996. doi: 10.1155/2022/6875996. eCollection 2022.ABSTRACTCervical cancer is one of the most common malignancies in women with high morbidity and mortality. Human papillomavirus (HPV) infection is the primary cause of cervical cancer, of which HPV 16 is the predominant. Early detection and effective treatment of cervical precancerous lesions are the key to preventing cervical cancer. Vitamin D receptor (VDR) gene polymorphism is considered to be an important cause of cancer development. Here, we studied the association of VDR polymorphisms (FOKI, BsmI, ApaI, and TaqI) in HPV16-positive c...
Source: Biomed Res - November 28, 2022 Category: Research Authors: Dongyan Li Yan Liu Dangyi Kong Dimitri Papukashvili Nino Rcheulishvili Hongwei Zhao Yinge Li Chaiyun Hou Jinfeng Ma Xiaoqing Lu Wenqi Bai Source Type: research

IJERPH, Vol. 19, Pages 15776: & ldquo;So, if she wasn & rsquo;t aware of it, then how would everybody else out there be aware of it? & rdquo; & mdash;Key Stakeholder Perspectives on the Initial Implementation of Self-Collection in Australia & rsquo;s Cervical Screening Program: A Qualitative Study
Conclusions: Whilst the introduction of self-collection was welcomed, clear communication from Government regarding setbacks in implementation and how to overcome these in practice were needed. As Australia moves to a policy of providing everyone eligible for screening the choice of self-collection, wider promotion to providers and eligible people, clarity around pathology processes and the scaling up of test availability, as well as timely education and communication of clinical management practice guidelines, are needed to ensure smoother program delivery in the future. Other countries implementing self-collection polici...
Source: International Journal of Environmental Research and Public Health - November 27, 2022 Category: Environmental Health Authors: Claire M. Zammit Nicola S. Creagh Tracey McDermott Megan A. Smith Dorothy A. Machalek Chloe J. Jennett Khic-Houy Prang Farhana Sultana Claire E. Nightingale Nicole M. Rankin Margaret Kelaher Julia M. L. Brotherton Tags: Article Source Type: research

Prevalence and Risk Factors of Genital Human Papillomavirus Infections among Women in Lagos, Nigeria
Trop Med Infect Dis. 2022 Nov 18;7(11):386. doi: 10.3390/tropicalmed7110386.ABSTRACTRegional variations exist in HPV prevalence worldwide despite reports of high prevalence rates among African women. Limited data on genital HPV prevalence necessitated this study with the aim of determining the prevalence of genital HPV and associated risk factors among women in Lagos, Nigeria. Exfoliated cervical cells were collected with consent from 165 women using a cervical brush. Viral DNA was extracted and amplified by nested PCR using two sets of consensus primers (MY09/11 and GP5+/6+). An unconditional logistic regression model was...
Source: Cancer Control - November 24, 2022 Category: Cancer & Oncology Authors: Oluwaseyi Sedowhe Ashaka Adesuyi Ayodeji Omoare Ayorinde Babatunde James Oluwapelumi Olufemi Adeyemi Femi Oladiji Kayode Adebamiji Adeniji Kehinde Sharafadeen Okunade Olajide Olubunmi Agbede Source Type: research

Countering Antivax Misinformation via Social Media: Message-Testing Randomized Experiment for Human Papillomavirus Vaccination Uptake
CONCLUSIONS: Evidence-based messages directly countering misinformation and promoting HPV vaccination in social media environments can positively influence parents' attitudes and behavioral intentions to vaccinate their children against HPV.PMID:36422887 | DOI:10.2196/37559 (Source: Cancer Control)
Source: Cancer Control - November 24, 2022 Category: Cancer & Oncology Authors: Sunny Jung Kim Jenna E Schiffelbein Inger Imset Ardis L Olson Source Type: research

Distribution and incidence of atypical glandular lesions in cervical cytology focusing on the association with high-risk human papillomavirus subtypes
In conclusion, most cases of HPV-associated glandular dysplastic changes and neoplasia occurred in sexually active women aged between 35 and 60 years. In addition, endocervical adenocarcinoma may occur at any age with or without an HPV infection.PMID:36419751 | PMC:PMC9677516 | DOI:10.3892/ol.2022.13592 (Source: Oncology Letters)
Source: Oncology Letters - November 24, 2022 Category: Cancer & Oncology Authors: Mahmoud Abbas Jan De Jonge Olaf Bettendorf Source Type: research

Prevention and treatment of human papillomavirus in men benefits both men and women
Men should not be overlooked in research on human papillomavirus (HPV) and its associated genital diseases. This is because men infected with HPV are not only at higher risk of genital cancers, but also increase their partners’ risk of HPV infection and reinfection through sexual contact. Herein, we summarized the state of knowledge regarding the prevention and treatment of HPV infection in men as well as the possible effects of the prevention and treatment of HPV in men on their female partners. Condom use, smoking cessation, male circumcision, and HPV vaccination for men each play an important role in preventing HPV in...
Source: Frontiers in cellular and infection microbiology - November 24, 2022 Category: Microbiology Source Type: research