Use of a carrageenan-based gel had no impact on anal HPVs 16 and 18 viral loads in gay, bisexual, and other men who have sex with men
J Med Virol. 2024 Mar;96(3):e29562. doi: 10.1002/jmv.29562.ABSTRACTThe Lubricant Investigation in Men to Inhibit Transmission of human papillomavirus (HPV) Infection randomized control trial in gay, bisexual, and other men who have sex with men (gbMSM) found that carrageenan use neither reduced acquisition of anal HPV infections nor influenced infection clearance. To investigate carrageenan's lack of protective effect, we compared the change in anal HPV16 and HPV18 viral loads following carrageenan use against placebo. We restricted our analysis to participants who completed the first four study visits and had a valid base...
Source: Cancer Control - March 26, 2024 Category: Cancer & Oncology Authors: Pareesa Kassam Mariam El-Zein Cassandra Laurie Joseph E Tota Pierre-Paul Tellier Fran çois Coutlée Alexandra de Pokomandy Eduardo L Franco Source Type: research

The importance of combined HPV and CINtec ® PLUS genotyping testing for p16 in women with cervical squamous cell carcinoma
CONCLUSIONS: The p16 marker (CINtec® PLUS) can be used as a prognostic biomarker and provides clinical usefulness through increased sensitivity (Se) and specificity (Sp) in the triage of women at risk of developing precancerous lesions, compared to cytology that is based on morphology, but has a rather low Se and high Sp, while HPV testing is very sensitive but slightly more specific.PMID:38527989 | DOI:10.47162/RJME.65.1.12 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - March 26, 2024 Category: General Medicine Authors: Toader Septimiu Void ăzan Mihaela Alexandra Budianu Ovidiu Simion Cotoi Sabin Gligore Turdean Source Type: research