A teenager with chest pain, a troponin below the limit of detection, and " benign early repolarization "
Sent by anonymous, written by Pendell MeyersA male in his teens presented with complaints of chest discomfort and dyspnea beginning while exercising but without obvious injury. He immediately stopped exercising and symptoms started to improve. Later that evening he felt recurrent central chest discomfort, shortness of breath, and vomited. Symptoms have been constant since this second episode, and are still present on arrival, which seems to have been less than 1 to 2 hours from onset of symptoms. No similar symptoms in the past. No prior exertional complaints of chest pain, dizziness, lightheadedness, or undue shortness of...
Source: Dr. Smith's ECG Blog - January 9, 2023 Category: Cardiology Authors: Pendell Source Type: blogs

Bonus Features – January 8, 2023 – Omnibus bill extends telehealth expansion through end of 2024, 60% of solution providers pouring all event marketing money into in-person events, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News On Dec. 29, 2022, President Biden signed the omnibus spending bill. The biggest news for healthcare IT was the extension of telehealth expansion under Medicare through the end of 2024. This includes expansion of originating...
Source: EMR and HIPAA - January 8, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT 4medica ADAPT AdvancedMD AHA Ardent Health Services Blendid Brian Berning Cadence Carenet Health Carol DeVol CharmHealth CipherHealth Comcast Healthcare CORL directtrust East Tennessee Health Information Netwo Source Type: blogs

Belt Monitors Heart Failure Patients
Researchers at Florida Atlantic University have developed a belt that can monitor heart failure patients for signs of disease progression. The wearable device measures heart rate, thoracic impedance, electrocardiogram, and motion, all of which can provide information on a heart failure patient’s status and potentially enable early detection of disease exacerbation. So far, the researchers have tested the device in a variety of everyday contexts, including routine activities, such as sitting, lying, standing, and walking, and found that it performs quite well. The researchers hope that the technology could help to reduce ...
Source: Medgadget - December 21, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Cardiology Diagnostics Telemedicine FloridaAtlantic heart failure Source Type: blogs

So Much to Do, So Little Selenium Needed
You may know that antioxidants can help protect your cells from oxidative damage, but do you know about selenium—an element often found in special proteins called antioxidant enzymes? Selenium is essential to your body, which means you must get it from the food you eat. But it’s a trace element so you only need a small amount to benefit from its effects. In addition to its antioxidant properties, it’s also important for reproduction, DNA synthesis, and hormone metabolism. In our bodies, selenium works in antioxidant enzymes to help protect us from oxidative damage. The element is also found in antidandruf...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - December 21, 2022 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Molecular Structures Cellular Processes Proteins Source Type: blogs

Netflix for Drugs?
By KIM BELLARD A relative — obviously overestimating my healthcare expertise — asked my thoughts on The New York Times article Can a Federally Funded ‘Netflix Model’ Fix the Broken Market for Antibiotics? I had previously skimmed the article and was vaguely aware of the Pasteur Act that it discusses, but, honestly, my immediate reaction to the article was, gosh, that may not be a great analogy: do people realize what a tough year Netflix has had? I have to admit that I tend to stay away from writing about Big Pharma and prescription drugs, mainly because, in a US healthcare system that seems to pride i...
Source: The Health Care Blog - December 21, 2022 Category: Consumer Health News Authors: matthew holt Tags: The Business of Health Care Congress Kim Bellard Netflix Pharma Pharmaceutical industry Source Type: blogs

Fight Aging! Newsletter, December 5th 2022
In conclusion, the PAAIs examined (i.e. mTOR loss of function, Ghrhr loss of function, intermittent fasting-based version of dietary restriction) often influenced age-sensitive traits in a direct way and not by slowing age-dependent change. Previous studies often failed to include young animals subjected to PAAI to account for age-independent PAAI effects. However, any study not accounting for such age-independent intervention effects will be prone to overestimate the extent to which an intervention delays the effects of aging on the phenotypes studied. This can result in a considerable bias of our view on how modifiable a...
Source: Fight Aging! - December 4, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

ECG Quiz with discussion – Pacing
ECG Quiz with discussion – Pacing What are the important findings and diagnosis? ECG shows a regular wide QRS rhythm at a rate of 60/minute. Each QRS complex is preceded by a narrow spike indicating ventricular paced rhythm. Dissociated P waves are seen suggesting that it is a single chamber ventricular pacing. Left bundle branch block pattern in I and aVL would mean right ventricular pacing. Inferior leads show negative QRS complexes indicating spread of activity from below upwards, suggesting right ventricular apical pacing. Right ventricular pacing causes left ventricular dyssynchrony and can cause left ventricul...
Source: Cardiophile MD - December 3, 2022 Category: Cardiology Authors: Johnson Francis Tags: ECG / Electrophysiology Source Type: blogs

Theorizing on Why the Heart Is Not Regenerative
After the central nervous system, heart muscle is one of the least capable tissues in the body when it comes to regeneration following injury. This is one of the contributing factors to the downward spiral of heart health in later life, particularly the cell death and scarring that occurs following the ischemia of a heart attack. Researchers here suggest that this lack of regenerative capacity is the rest of an adaptation in the nuclear membrane that protects heart cells from other damaging circumstances by reducing the number of pathways that allow signal molecules to pass into the cell nucleus. That is protective against...
Source: Fight Aging! - December 2, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

When Does the Heart Become Larger versus Smaller in Old Age?
As you may know, the aging heart often exhibits ventricular hypertrophy, an enlargement and weakening of the muscle. This appears driven in large part by the increased burden of cellular senescence in later life, given reversal of hypertrophy observed after senolytic treatment in old animals. This hypertrophy can also be thought as a downstream consequence of hypertension, but biology is rarely so simple as to have a single line of cause and effect. As noted in this paper, people lose muscle mass and strength with age, leading to the weakness and frailty of sarcopenia. The heart is a muscle, and a shrinking of that muscle ...
Source: Fight Aging! - November 30, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

What is the commonest sustained arrhythmia in HCM?
Commonest sustained arrhythmia in hypertrophic cardiomyopathy is atrial fibrillation. Atrial fibrillation (AF) can occur in about 1/5th of cases of hypertrophic cardiomyopathy (HCM). Factors predisposing to AF in HCM are left atrial pressure and size due to left ventricular diastolic dysfunction, left ventricular outflow tract obstruction and mitral regurgitation. About one fourth of them may develop embolic episodes and stroke. It has been suggested that those with left atrial diameter of 45 mm or more should undergo 48 hour Holter once or twice a year to look for AF. Anticoagulation is recommended in those with AF ...
Source: Cardiophile MD - November 23, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

What is paroxysmal nocturnal dyspnea?
In paroxysmal nocturnal dyspnea, patient wakes up with breathlessness and sits up or even stands. It is relieved over a few minutes. Paroxysmal nocturnal dyspnea is different from orthopnea which occurs soon after assuming the supine position and is relieved by sitting up. Orthopnea has no relation to sleep. Onset of paroxysmal nocturnal dyspnea is delayed after onset of sleep as it takes some time for the peripheral edema fluid to get absorbed and translocate to the lungs. PND usually occurs 2 – 4 hours after onset of sleep. Sympathetic withdrawal during sleep is also a proposed mechanism. Paroxysmal nocturnal dyspnea ...
Source: Cardiophile MD - November 22, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Fight Aging! Newsletter, November 21st 2022
In this study researchers added new insight, showing that high-intensity aerobic exercise, which derives its energy from sugar, can reduce the risk of metastatic cancer by as much as 72%. If so far the general message to the public has been 'be active, be healthy', now researchers can explain how aerobic activity can maximize the prevention of the most aggressive and metastatic types of cancer. The study combined an animal model in which mice were trained under a strict exercise regimen, with data from healthy human volunteers examined before and after running. The human data, obtained from an epidemiological study ...
Source: Fight Aging! - November 20, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Anemia in cardiac failure : Needs little more attention
HF is the inability (or reduced ability) to supply oxygen and other nutrients to fulfill the body’s demands. In the process, the heart either fights or flights, and results in symptoms due to hemodynamic alterations, or adversities of neuro-hormonal activation. Now, what is Anemia? Anemia is a condition with reduced or dysfunctional RBCs. that directly interferes with oxygen delivery to tissues. It is not at all a coincidence, the core functions of the heart and blood are strikingly similar and intertwined. While the heart is the powerhouse of the circulatory system, without good-quality blood, the greatness of th...
Source: Dr.S.Venkatesan MD - November 19, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized anemia in cardiac failure Source Type: blogs

What do you think of this " Ventricular Bigeminy " ?
Written by Bobby Nicholson MD, with edits by MeyersA woman in her 50s with past medical history of heart failure, prior stroke, atrial fibrillation on Eliquis, lung cancer in remission, and CKD, presented to the emergency department for evaluation of cough and shortness of breath. EKG was obtained in triage and read as ventricular bigeminy. What do you think?On my first read of the EKG, I agreed with the initial interpretation. Pendell Meyers then recommended that I take a second look at the morphology of the QRS complexes. I think it was easiest for me to see in the rhythm strip, but there are clearly P waves in front of ...
Source: Dr. Smith's ECG Blog - November 19, 2022 Category: Cardiology Authors: Pendell Source Type: blogs

What are the important biomarkers for myocardial fibrosis?
Soluble ST2 receptor and Galectin-3 are important biomarkers of myocardial fibrosis. Reference Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Colvin MM, Drazner MH, Filippatos GS, Fonarow GC, Givertz MM, Hollenberg SM, Lindenfeld J, Masoudi FA, McBride PE, Peterson PN, Stevenson LW, Westlake C. 2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Circulation. 2017 Aug 8;136(6):e137-e161. (Source: Cardiophile MD)
Source: Cardiophile MD - November 17, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs