Kento Health Raises $4.1 Million CAD to Bring AI to Cardiovascular Care
Dialogue Alumni’s New Startup is Gearing up to Strike Hard in the Battle Against the Leading Cause of Death Montréal-based healthtech startup Kento Health has closed a $4.1 million CAD ($3 million USD) pre-seed financing round. The round was led by Boreal Ventures and N49P and saw participation from Broom Ventures, Graphite Ventures, and several other strategic angel investors as well as an undisclosed US-based medical institution. Kento claims it is poised to make a substantial impact in the fight against the world’s leading cause of death by using technology like artificial intelligence (AI). “This funding not...
Source: EMR and HIPAA - November 8, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Alex Norman Boreal Ventures Broom Ventures David Charbonneau Dialogue Health Graphite Ventures Health IT Funding Health IT Fundings Health IT Investment Jonah Davies Kento Kento Health Max Leca Source Type: blogs

Atrial DCM : A new entity in the making
A brief learning session with cardiology fellow about a possible new concept in Left heart failure. What is the commmest cause for acute pulmonary edema? “Left sided heart failure” “Can you be more specific , Left sided means ? “I meant LV failure , typically DCM of any cause or Severe un-controlled HT” “Ok .good. Does Left Heart failure include mitral valve dysfunction also ? “Yes sir, very much. Classical mitral stenosis and Isolated MR can cause pulmonary edema. In fact, acute AR Iis also part of left heart disease” So far, so good, now coming to t...
Source: Dr.S.Venkatesan MD - November 4, 2023 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Atrail dcm atrial cardiomyopathy HFpEF la pressure volume loop primary atrial failure Source Type: blogs

" Non-STEMI " is a worthless term.
A 60 yo with 2 previous inferior (RCA) STEMIs, stented, called 911 for one hour of chest pain. He had no h/o heart failure. Here is the first prehospital ECG (time 0, after one hour of pain): I do not see evidence of OMI, and neither did the Queen of HeartsHere is the 2nd prehospital ECG (time 10 minutes, after 70 minutes of pain): No changeOn arrival, the first ED ECG was recorded 20 minutes after the last one (90 minutes after pain onset): What do you think?Here is his most recent previous ECG:This was recorded after intervention for inferior STEMI (with massive ST Elevation, see below), and shows inf...
Source: Dr. Smith's ECG Blog - October 30, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

Bonus Features – October 29, 2023 – 66% of patients prefer email or text for reminders about medical bills, 94% of clinicians said lack of timely access to insights within EHR impacts patient care, and 28 more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News CMMI released the 2022 performance results for the direct contracting value-based care model, which has since been redesigned and renamed the ACO REACH Model. All told, participating entities achieved net savings of more t...
Source: EMR and HIPAA - October 29, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT 1upHealth ACO REACH AGS Health Avenda Health Bluefin California HHS Carestream Dental CB Insights Cedar Gate Technologies CMMI CORE eClinicalWorks Fivetran Found Freshpaint FutureRx GSR Ventures Healthcare Source Type: blogs

Continuous prolonged generalized weakness, lightheadedness, and presyncope. What might you suspect from the ECG?
A young man presented with continuous prolonged generalized weakness, lightheadedness, and presyncope. There was some dyspnea but no chest pain.  Here is his ECG.  This shows LVH, with high voltage.LVH can have very thick-walled ventricles and a correspondingly small LV cavity.  LVH is a common etiology of heart failure with preserved ejection fraction, as it may results in a stiff ventricle with poor diastolic relaxation.See this articles: Heart Failure with Preserved Ejection Fraction (NEJM review)One etiology of LVH on the ECG is Hypertrophic Cardiolmyopathy (HOCM), and sometimes ECGs in pa...
Source: Dr. Smith's ECG Blog - October 28, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

Rate vs Rhythm Control in Atrial Fibrillation
Rate vs rhythm control as a management strategy in atrial fibrillation has been a long standing topic for debate. Though at one look rhythm control would appear to be the ideal strategy, long term adverse effects of the currently available medications for rhythm control is the often cited down side. AFFIRM [1] and RACE [2] trials were the main reason for the debate as they failed to show any benefit for the rhythm control strategy. AF-CHF trial in those with AF and congestive heart failure also failed to show any advantage for the rhythm control strategy [3]. But there have been important criticisms as well [4]. In AFFIRM...
Source: Cardiophile MD - October 26, 2023 Category: Cardiology Authors: Johnson Francis Tags: ECG / Electrophysiology General Cardiology Source Type: blogs

A 20-something woman with cardiac arrest.
The patient is a 20 something female. She is healthy with no known cardiac disease. She was admitted to the neurology department due to headache and vomiting. She was found to have a viral CNS infection. A few days into her hospital stay she developedchest discomfort and the following ECG was recorded. What do you think? Why such large T-waves?  Are these hyperacute T-waves? Are these ECG changes related to the CNS infection perhaps? What disease processes would you put on your list of differential diagnoses?When I saw the ECG of this patient I saw that there was definitely something " off " . I didn ' t get...
Source: Dr. Smith's ECG Blog - October 18, 2023 Category: Cardiology Authors: Magnus Nossen Source Type: blogs

Current Role of Digoxin in Heart Failure as Per Guidelines and DIGIT-HF trial of Digitoxin
Use of digoxin in heart failure has come down markedly over the past decades due to concerns of toxicity and availability of more effective medications. Concern for toxicity is because of the narrow therapeutic window of digoxin along with interactions with other cardiovascular drugs and in those with renal dysfunction, which can enhance toxicity. Though an initial loading dose was given earlier, it is no longer used. As per the 2021 ESC guidelines, digoxin may be considered in heart failure with reduced ejection fraction, in sinus rhythm for reducing risk of hospitalizations, though there is no mortality benefit. It may ...
Source: Cardiophile MD - October 16, 2023 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Fight Aging! Newsletter, October 16th 2023
In conclusion, a number of studies have shown that CD4+ Treg cells are crucial in the maintenance of peripheral tolerance and have an important role in the control of atherosclerosis-related inflammation. Therefore, Treg cells are a promising target of major research efforts focused on immune-modulating therapies against atherosclerosis. Developing anti-atherosclerotic Treg-based therapies faces challenges. However, rapid progress in genetic, epigenetic, and molecular aspects of cellular immunology gives hope for a fast-track solution. « Back to Top Delivering Senolytic Nanoparticles to Atheroscle...
Source: Fight Aging! - October 15, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

This ECG was texted to me after the fact with no information. What do you think?
This ECG was texted to me with no other information, with this quote: " You will see this in the Queen of Hearts. "  I assumed it was in real time.The Queen said " Not OMI with low confidence "What do you think?The conventional algorithm said: SINUS RHYTHMABNORMAL QRS-T ANGLE [QRS-T AXIS DIFFERENCE> 60]ABNORMAL ECG This was my response: " I am not certain that I agree with the queen on this one. Be careful with it.  Notice that the Queen has low confidence. "Why am I worried?  The T-waves are quite tall.  Although most hyperacute T-waves are bulky, wide, fat and symmetric in propo...
Source: Dr. Smith's ECG Blog - October 13, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

Adoptive Transfer of Regulatory T Cells as a Way to Treat Atherosclerosis
In conclusion, a number of studies have shown that CD4+ Treg cells are crucial in the maintenance of peripheral tolerance and have an important role in the control of atherosclerosis-related inflammation. Therefore, Treg cells are a promising target of major research efforts focused on immune-modulating therapies against atherosclerosis. Developing anti-atherosclerotic Treg-based therapies faces challenges. However, rapid progress in genetic, epigenetic, and molecular aspects of cellular immunology gives hope for a fast-track solution. (Source: Fight Aging!)
Source: Fight Aging! - October 11, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, October 9th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - October 8, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

What is the infarct artery? What does the post PCI ECG show? What does the convalescent ECG show?
What is the infarct artery? I usually don ' t ask this question, as it is rarely relevant to the decision to activate the cath lab.  This is one case where it made a difference: Right Ventricular MI seen on ECG helps Angiographer to find Culprit LesionNevertheless, it is sometimes a fun academic exercise to try to predict the infarct artery:An elderly patient had onset of chest pain one hour prior.  He called 911.  Here is the prehospital ECG.What do you think?I think it looks like an inferior posterior OMI.  The medics thought so too and activated the cath lab from the prehospital.The Qu...
Source: Dr. Smith's ECG Blog - October 6, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

Continued Study of Urolithin A to Improve Mitochondrial Function
Urolithin A is one of a number of compounds available as supplements that can improve mitochondrial function in older individuals. Like others, urolithin A may function by improving the mitochondrial quality control process of mitophagy, responsible for removing damaged and worn mitochondria. Mitophagy becomes less efficient with age, and this is one of the contributing factors to age-related loss of mitochondrial function and its harmful impact on tissues. Like other supplement based approaches to improving mitochondrial function, it is likely that regular exercise delivers larger gains than those demonstrated for supplem...
Source: Fight Aging! - October 2, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, September 25th 2023
In conclusion, this individual patient data meta-analysis of longitudinal cohort studies found that antihypertensive use was associated with decreased dementia risk compared with individuals with untreated hypertension through all ages in late life. Individuals with treated hypertension had no increased risk of dementia compared with healthy controls. « Back to Top Results from Human Clinical Trials Do Not Support Metformin as a Longevity Drug https://www.fightaging.org/archives/2023/09/results-from-human-clinical-trials-do-not-support-metformin-as-a-longevity-drug/ The SENS Research Fou...
Source: Fight Aging! - September 24, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs