Alcohol Hangover Across the Lifespan: Impact Of Sex and Age
ConclusionsHangover severity declines with age, even after controlling for eBAC or the amount of alcohol consumed. Sex differences were greatest in the younger age groups but became significantly smaller or absent in the older age groups. The relationship between age and hangover severity is strongly mediated by subjective intoxication. Pain sensitivity, lower with aging, might be a mediator. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - April 5, 2021 Category: Addiction Source Type: research

Nuanced relations between simultaneous alcohol and cannabis use motives and negative consequences among college students: The role of multiple product use.
We examined within-person effects of motives (effect-enhancement, social, offered [it was offered], coping) on number of negative consequences and on experiencing hangover, nausea, or blackout; and indirect effects via two concurrent mediators: using multiple alcohol products and multiple cannabis products. Total effect models showed effect-enhancement motives were related to nausea, social motives to number of total consequences and hangover, and coping motives to blackout. Effect-enhancement, social, and offered motives evinced significant indirect effects on consequence outcomes via multiple alcohol, but not cannabis, p...
Source: Experimental and Clinical Psychopharmacology - March 11, 2021 Category: Psychiatry & Psychology Source Type: research

Nuanced relations between simultaneous alcohol and cannabis use motives and negative consequences among college students: The role of multiple product use.
We examined within-person effects of motives (effect-enhancement, social, offered [it was offered], coping) on number of negative consequences and on experiencing hangover, nausea, or blackout; and indirect effects via two concurrent mediators: using multiple alcohol products and multiple cannabis products. Total effect models showed effect-enhancement motives were related to nausea, social motives to number of total consequences and hangover, and coping motives to blackout. Effect-enhancement, social, and offered motives evinced significant indirect effects on consequence outcomes via multiple alcohol, but not cannabis, p...
Source: Experimental and Clinical Psychopharmacology - March 11, 2021 Category: Psychiatry & Psychology Source Type: research

Response to Letter by Benson et  al. on ‘Hangover and the Effects of L-Cysteine’
We are grateful toBensonet  al. (2021) for their interest in our report on Hangover and the Effects of L-Cysteine (Erikssonet  al., 2020). Their first criticism concerned our use of correlations in analyzing the data. We believe that the finding of significant correlations, all in the same direction, does support the hypothesis that L-cysteine alleviates and/or prevents hangover symptoms. Regarding our choice to place statistical results in the Figure legends, we suggest that readers often look more at the Figures than the text, especially when, as in our paper, original data are displayed in the Figures. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - February 25, 2021 Category: Addiction Source Type: research

IJERPH, Vol. 18, Pages 2047: The Relationship between Pain Sensitivity, Pain Catastrophizing and Hangover Severity
In conclusion, although statistically significant, the observed correlations were of small magnitude. Nevertheless, the observations confirm previous findings that suggest a link between pain perception, alcohol consumption, and hangover severity, which warrants further investigation. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - February 19, 2021 Category: Environmental Health Authors: Hama M. Saeed Annabel S. M. Sips Lauren J. Owen Joris C. Verster Tags: Article Source Type: research

Molecules, Vol. 26, Pages 903: Hovenia dulcis Thumberg: Phytochemistry, Pharmacology, Toxicology and Regulatory Framework for Its Use in the European Union
quale Pierimarchi Hovenia dulcis Thunberg is an herbal plant, belonging to the Rhamnaceae family, widespread in west Asia, USA, Australia and New Zealand, but still almost unknown in Western countries. H. dulcis has been described to possess several pharmacological properties, such as antidiabetic, anticancer, antioxidant, anti-inflammatory and hepatoprotective, especially in the hangover treatment, validating its use as an herbal remedy in the Chinese Traditional Medicine. These biological properties are related to a variety of secondary metabolites synthesized by the different plant parts. Root, bark and leaves are r...
Source: Molecules - February 9, 2021 Category: Chemistry Authors: Gianluca Sferrazza Gloria Brusotti Manuela Zonfrillo Caterina Temporini Sara Tengattini Monica Bononi Fernando Tateo Enrica Calleri Pasquale Pierimarchi Tags: Review Source Type: research

L-cysteine and the Treatment of Alcohol Hangover: A Commentary on Eriksson et  al. (2020)
To the Editor: (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - February 1, 2021 Category: Addiction Source Type: research

[ASAP] Coarse-Grained Force Fields from the Perspective of Statistical Mechanics: Better Understanding of the Origins of a MARTINI Hangover
Journal of Chemical Theory and ComputationDOI: 10.1021/acs.jctc.0c00638 (Source: Journal of Chemical Theory and Computation)
Source: Journal of Chemical Theory and Computation - January 21, 2021 Category: Chemistry Authors: Zack Jarin, James Newhouse, and Gregory A. Voth Source Type: research

Fun/intoxication pre-drinking motives lead indirectly to more alcohol-related consequences via increased alcohol consumption on a given night.
CONCLUSION: This study shows that predominantly 'fun/intoxication' predrinkers are at increased risk for alcohol consumption and consequences, but not those who predrink for conviviality or facilitation motives. The outcomes thus suggest the importance of specific PDM in preventing alcohol use for instance by tailoring interventions based on individuals' PDM in order to curb drinking and its associated consequences among young adults on weekend nights out. PMID: 33276233 [PubMed - as supplied by publisher] (Source: Addictive Behaviors)
Source: Addictive Behaviors - November 27, 2020 Category: Addiction Authors: Smit K, Kuntsche E, Anderson-Luxford D, Labhart F Tags: Addict Behav Source Type: research

Non-Beverage Alcohol Consumption In Izhevsk: 15  Years Later
ConclusionNon-beverage alcohol consumption still took place at Izhevsk, a typical Russian city, in 2018, and its availability was still high. Untaxed and cheap medicinal non-beverage alcohol consumption seems to have become the major source of non-beverage alcohol consumption. Further regulation of non-beverage alcohol may be required in Russia. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - November 14, 2020 Category: Addiction Source Type: research

Does Alcohol Hangover Affect Emotion Regulation Capacity? Evidence From a Naturalistic Cross-Over Study Design
ConclusionThese results suggest that emotion regulation in everyday life and emotional reactivity may be adversely affected by alcohol hangover, but some emotion regulation strategies (e.g. deliberate cognitive reappraisal) may be unaffected. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - November 12, 2020 Category: Addiction Source Type: research

Gender Differences in the Epidemiology of Alcohol Use and Related Harms in the United States.
Authors: White AM Abstract Over the past century, differences in alcohol use and related harms between males and females in the United States have diminished considerably. In general, males still consume more alcohol and experience and cause more alcohol-related injuries and deaths than females do, but the gaps are narrowing. Among adolescents and emerging adults, gaps in drinking have narrowed primarily because alcohol use among males has declined more than alcohol use among females. Among adults, alcohol use is increasing for women but not for men. Rates of alcohol-related emergency department visits, ho...
Source: Alcohol Research - November 4, 2020 Category: Addiction Tags: Alcohol Res Source Type: research

Complementary medicines advertising policy Part II: unethical conduct in the Australian market after July 2018.
ConclusionsComplaint classification and actions taken by the TGA were inconsistent. The TGA's new compliance powers were rarely applied. The new complaint system is less transparent than the one it replaced. There is a high rate of advertising complaints and a low rate of effective regulatory response. Time-based KPIs should be based on outcome measures, not when a case is closed by a process measure. An urgent review of the new system is required. Comment on Australia's 2018 Royal Commission into Misconduct in Banking is equally applicable to the TGA: 'Essentially a failure to enforce the law undermines the authority of t...
Source: Australian Health Review - October 19, 2020 Category: Hospital Management Authors: Harvey K, Vickers M, Arnold BB Tags: Aust Health Rev Source Type: research

The Feasibility, Tolerability, and Safety of Administering a Very High Alcohol Dose to Drinkers with Alcohol Use Disorder.
CONCLUSION: Results support the feasibility, tolerability, and safety of administering a very high alcohol dose to young adult drinkers with AUD within the context of a well-validated laboratory alcohol challenge paradigm. Utilizing an alcohol dose more consistent with naturalistic drinking patterns may foster greater ecological validity of laboratory paradigms for persons with moderate to severe AUD. PMID: 33038271 [PubMed - as supplied by publisher] (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - October 10, 2020 Category: Addiction Authors: Vena A, Howe M, Fridberg D, Cao D, King AC Tags: Alcohol Clin Exp Res Source Type: research