Gender Differences in the Epidemiology of Alcohol Use and Related Harms in the United States.
Authors: White AM Abstract Over the past century, differences in alcohol use and related harms between males and females in the United States have diminished considerably. In general, males still consume more alcohol and experience and cause more alcohol-related injuries and deaths than females do, but the gaps are narrowing. Among adolescents and emerging adults, gaps in drinking have narrowed primarily because alcohol use among males has declined more than alcohol use among females. Among adults, alcohol use is increasing for women but not for men. Rates of alcohol-related emergency department visits, hospitaliza...
Source: Alcohol Research - November 4, 2020 Category: Addiction Tags: Alcohol Res Source Type: research

Complementary medicines advertising policy Part II: unethical conduct in the Australian market after July 2018.
ConclusionsComplaint classification and actions taken by the TGA were inconsistent. The TGA's new compliance powers were rarely applied. The new complaint system is less transparent than the one it replaced. There is a high rate of advertising complaints and a low rate of effective regulatory response. Time-based KPIs should be based on outcome measures, not when a case is closed by a process measure. An urgent review of the new system is required. Comment on Australia's 2018 Royal Commission into Misconduct in Banking is equally applicable to the TGA: 'Essentially a failure to enforce the law undermines the authority of t...
Source: Australian Health Review - October 19, 2020 Category: Hospital Management Authors: Harvey K, Vickers M, Arnold BB Tags: Aust Health Rev Source Type: research

The Feasibility, Tolerability, and Safety of Administering a Very High Alcohol Dose to Drinkers with Alcohol Use Disorder.
Abstract INTRODUCTION: There remains a paucity of research quantifying alcohol's effects in drinkers with alcohol use disorder (AUD), particularly responses to very high alcohol doses (≥0.8 g/kg). As drinkers with AUD frequently engage in very heavy drinking (8-10 drinks/occasion), doses of ≤ 0.8 g/kg may lack ecological validity. The present study examined the feasibility, tolerability, and safety of administering a very high alcohol dose (1.2 g/kg) to non-treatment seeking AUD participants. METHODS: Sixty-one young-adult AUD drinkers enrolled in the Chicago Social Drinking Pro...
Source: Alcoholism, Clinical and Experimental Research - October 10, 2020 Category: Addiction Authors: Vena A, Howe M, Fridberg D, Cao D, King AC Tags: Alcohol Clin Exp Res Source Type: research

Regret Me Not: Examining the Relationship between Alcohol Consumption and Regrettable Experiences.
Conclusions: These findings suggest high prevalence of regrettable experiences, that are predicted by increased alcohol consumption. However, there was little evidence that increased number of experiences predicted future drinking intentions. Regrettable experiences are prevalent following consumption, however a focus on these regrets to deter future alcohol consumption may not be an effective psychological intervention. PMID: 32924717 [PubMed - as supplied by publisher] (Source: Substance Use and Misuse)
Source: Substance Use and Misuse - September 16, 2020 Category: Addiction Tags: Subst Use Misuse Source Type: research

A Review on Opuntia Species and its Chemistry, Pharmacognosy, Pharmacology and Bioapplications
Conclusion: Different parts of Opuntia plant (fruits, seeds, flowers and cladodes) are used in various health problems which include wound healing, anti-inflammatory and urinary tract infection from ancient times. Nowadays, researches have extended several pharmacological and therapeutic uses of Opuntia species as discussed in this review. Many in-vitro and in-vivo models are also discussed in this review as the proofs of research findings. Various research gaps have been observed in current studies that require attention in the future. (Source: Current Nutrition and Food Science)
Source: Current Nutrition and Food Science - September 10, 2020 Category: Nutrition Source Type: research

FDA Targets Illegal Hangover Relief
Forget the Happy Hour Vitamins, milk thistle, and prickly pear. Not only will they fail to prevent or cure a hangover, the FDA said they ’re illegally being marketed as remedies for having one too many. (Source: JAMA)
Source: JAMA - September 1, 2020 Category: General Medicine Source Type: research

Corrigendum to: L-Cysteine Containing Vitamin Supplement Which Prevents or Alleviates Alcohol-related Hangover Symptoms: Nausea, Headache, Stress and Anxiety
In the above article the Y axis on Figure 2A was numbered 0-4 instead of 0-8. This has now been corrected online. The author apologises for the error. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - August 28, 2020 Category: Addiction Source Type: research

L-Cysteine Containing Vitamin Supplement Which Prevents or Alleviates Alcohol-related Hangover Symptoms: Nausea, Headache, Stress and Anxiety
ConclusionsL-cysteine would reduce the need of drinking the next day with no or less hangover symptoms: nausea, headache, stress and anxiety. Altogether, these effects of L-cysteine are unique and seem to have a future in preventing or alleviating these harmful symptoms as well as reducing the risk of alcohol addiction. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - August 18, 2020 Category: Addiction Source Type: research

Self-Induced Vomiting and Other Impulsive Behaviors in Alcohol Use Disorder: A Cross-sectional Descriptive Study.
Conclusions: Almost a third of patients with AUD reported SIV. BITE scores indicated no relationship between eating disorders and alcohol-related SIV in this sample. Our findings also did not support an etiological role for impulsivity in alcohol-related SIV. PMID: 32772700 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - August 13, 2020 Category: Addiction Tags: J Dual Diagn Source Type: research

The Effect of Dihydromyricetin, a Natural Flavonoid, on Morphine-induced Conditioned Place Preference and Physical Dependence in Mice
Conclusion These results indicated that DHM decreased acquisition and expression of morphine CPP and inhibited development of morphine-induced physical dependence. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Drug Research)
Source: Drug Research - July 16, 2020 Category: Drugs & Pharmacology Authors: Etemad, Leila Farkhari, Hadi Alavi, Mohaddeseh Sadat Roohbakhsh, Ali Tags: Original Article Source Type: research

Hangover and fatigue: effects of Robuvit ® supplementation. A pilot registry study.
Hangover and fatigue: effects of Robuvit® supplementation. A pilot registry study. Minerva Cardioangiol. 2020 Jun;68(3):203-208 Authors: Hu S, Belcaro G, Cesarone MR, Scipione C, Scipione V, Hosoi M, Cornelli U, Pellegrini L, Dugall M, Feragalli B, Cotellese R Abstract BACKGROUND: The aim of this open registry study was to evaluate the effects of Robuvit® in subjects with hangover after acute alcohol consumption also measuring changes in levels of oxidative stress. A group using standard management (SM) and a group using SM and Robuvit® 300 mg/day for 3 days were compared. METHODS: Nine...
Source: Minerva Cardioangiologica - June 27, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Plant Extracts May Relieve Hangover Symptoms, Trial Suggests
A dietary supplement drink containing plant extracts improved hangover symptoms after moderate alcohol consumption in a trial published in BMJ Nutrition, Prevention& Health. (Source: JAMA)
Source: JAMA - June 23, 2020 Category: General Medicine Source Type: research

239 Multi-functional in vitro and in vivo efficacy of Tiliacora triandra, natural ingredient with clinical anti-aging skin benefits
Tiliacora triandra is a flowering plant also known as “bai yanang”. It is native to Southeast Asia and used particularly in the cuisines of northeast Thailand and Laos. Traditionally recommended for fever reduction and for relief from hangover. Pharmacological activities include anti-bacterial, anti-fungal, and anti-inflammatory properties, suggest ing its adaptogenic function. The present study is to identify biological endpoints of proprietary extract of T.triandra. Testing in vitro in 3D skin model showed strong effect on hyaluronic acid production. (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - June 17, 2020 Category: Dermatology Authors: J. Idkowiak-Baldys, F. Liebel, J.R. Glynn Tags: Epidermal Structure and Barrier Function Source Type: research

IJERPH, Vol. 17, Pages 4324: The Association between Ethanol Elimination Rate and Hangover Severity
s C Verster Assessments in blood and saliva suggests that the amount of ethanol present in the first hours after alcohol consumption and into the following morning is associated with hangover severity. The current analysis determines how ethanol elimination rate is related to hangover severity reported throughout the day. n = 8 subjects participated in two studies. The first was a naturalistic study comprising an evening of alcohol consumption. Hangover severity was assessed hourly from 10 a.m. to 4 p.m., using a 1-item hangover severity scale ranging from 0 (absent) to 10 (extreme). The second study comprised a highly...
Source: International Journal of Environmental Research and Public Health - June 16, 2020 Category: Environmental Health Authors: Marlou Mackus Aurora JAE van de Loo Johan Garssen Aletta D Kraneveld Andrew Scholey Joris C Verster Tags: Article Source Type: research

IJERPH, Vol. 17, Pages 4039: Perceived Immune Fitness, Individual Strength and Hangover Severity
d Verster Various factors may contribute to alcohol hangover severity. The purpose of the current investigation was to evaluate the possible impact of alcohol consumption patterns, perceived immune status, and baseline fatigue on hangover severity. A survey was completed by a convenience sample of N = 199 Dutch students who reported on their latest past month’s heavy drinking occasion, including subjective intoxication (perceived drunkenness) and next-day hangover severity, which were rated on single-item scales ranging from 0 (absent) to 10 (extreme). In addition, perceived (momentary) immune fitness ...
Source: International Journal of Environmental Research and Public Health - June 4, 2020 Category: Environmental Health Authors: van de Loo Kerssemakers Scholey Garssen Kraneveld Verster Tags: Article Source Type: research

ZBiotics raises funds for hangover probiotic
(Source: Chemical and Engineering News)
Source: Chemical and Engineering News - March 21, 2020 Category: Chemistry Authors: Ryan Cross Source Type: research

Effect of single-dose, oral enzymatic porcine placental extract(EPPE) on pharmacokinetics of alcohol and liver function in rats.
CONCLUSIONS: The single-dose EPPE (0.5~2.5 g/kg) suppressed absorption of alcohol in the gastrointestinal tract. This may be useful in preventing hangover effects and toxicity after drinking alcohol and may also preserve liver health after alcohol ingestion. PMID: 32154587 [PubMed - as supplied by publisher] (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - March 9, 2020 Category: Addiction Authors: Kim HJ, Kim S, Seo JS, Bae GW, Kim KN, Kang JS Tags: Alcohol Clin Exp Res Source Type: research

Optimization of Protoplast Preparation and Regeneration of a Medicinal Fungus Antrodia cinnamomea.
Authors: Wu JD, Chou JC Abstract Antrodia cinnamomea is a unique medicinal fungus in Taiwan. It has been found rich in some pharmacologically active compounds for anti-cancer, hangover, and immune regulation etc. With the in-depth study of these components, it would be interesting and important to establish a molecular system for basic studies of A. cinnamomea. Thus, we would like to set up a foundation for this purpose by studying the A. cinnamomea protoplast preparation and regeneration. Firstly, we studied the optimization method of protoplast preparation of A. cinnamomea, and found various factors that may affe...
Source: Mycobiology - February 7, 2020 Category: Biology Tags: Mycobiology Source Type: research

Honeymoon or hangover? How election outcomes produce emotional shifts to winning candidate smiles
This study examines changes in self-reported happiness, anger, and distress to different smile types expressed by Barack Obama and Mitt Romney, measured immediately prior to and again following the 2012 presidential election. A panel of online respondents (N = 214) were shown four video clips featuring different smile types from each candidate before and after the election. Obama's clips featured an amusement and controlled-amusement smile, while Romney's featured a posed and contempt smiles. Findings revealed significant differences in self-reported emotional response to Obama. Followers of Obama reported an increase ...
Source: Personality and Individual Differences - September 26, 2019 Category: Psychiatry & Psychology Source Type: research

Event-level correlates of drinking events characterized by alcohol-induced blackouts.
CONCLUSIONS: Event-level findings of this study document that events leading to alcohol-induced memory loss are associated with other adverse experiences relative to drinking events that do not result in blackout, and offer potentially motivational levers for preventive interventions. PMID: 31557348 [PubMed - as supplied by publisher] (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - September 25, 2019 Category: Addiction Authors: Merrill JE, Boyle HK, Jackson KM, Carey KB Tags: Alcohol Clin Exp Res Source Type: research

Exploring the emotional experiences of alcohol hangover syndrome in healthy UK-based adults
. (Source: Drugs: Education, Prevention, and Policy)
Source: Drugs: Education, Prevention, and Policy - August 26, 2019 Category: Addiction Authors: Ian James Milton Elizabeth Sillence Melanie Mitchell Source Type: research

The world's first GMO probiotic is for sale; it's designed to prevent hangovers
The product, made by ZBiotics, is regulated as a food, not a drug, and has not been formally vetted for effectiveness in humans (Source: Chemical and Engineering News)
Source: Chemical and Engineering News - August 21, 2019 Category: Chemistry Authors: Ryan Cross Source Type: research

The first GMO probiotic is for sale; it's designed to prevent hangovers
The product, made by ZBiotics, is regulated as a supplement, not a drug, and has not been vetted for effectiveness in humans (Source: Chemical and Engineering News)
Source: Chemical and Engineering News - August 19, 2019 Category: Chemistry Authors: Ryan Cross Source Type: research

The world's first GMO probiotic is for sale; it's designed to prevent hangovers
The product, made by ZBiotics, is regulated as a food, not a drug, and has not been vetted for effectiveness in humans (Source: Chemical and Engineering News)
Source: Chemical and Engineering News - August 19, 2019 Category: Chemistry Authors: Ryan Cross Source Type: research

Dihydromyricetin: A review on identification and quantification methods, biological activities, chemical stability, metabolism and approaches to enhance its bioavailability
Publication date: Available online 25 July 2019Source: Trends in Food Science & TechnologyAuthor(s): Dan Liu, Yiqin Mao, Lijun Ding, Xin-An ZengAbstractBackgroundDihydromyricetin (DMY) is an important plant flavonoid, which has received great attention due to its health-benefiting, including antioxidant, antimicrobial, anti-inflammatory, anticancer, antidiabetic and neuroprotective activities. DMY capsules have been sold in US as a nutraceutical supplement to prevent alcoholic hangovers. The major disadvantage associated with DMY is its chemical instability and poor bioavailability caused by the combined effects of its...
Source: Trends in Food Science and Technology - July 27, 2019 Category: Food Science Source Type: research

Social and Situational Party Characteristics Associated With High-Intensity Alcohol Use Among Youth and Young Adults.
CONCLUSIONS: Results from this study indicate there are unique precursors and consequences of high-intensity alcohol consumption among youth and young adults. These environmental factors associated with high-risk drinking contexts can be used to develop prevention strategies to mitigate the harms associated with excessive alcohol consumption. PMID: 31313331 [PubMed - as supplied by publisher] (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - July 15, 2019 Category: Addiction Authors: Cox MJ, Egan KL, Suerken CK, Reboussin BA, Song EY, Wagoner KG, Wolfson M Tags: Alcohol Clin Exp Res Source Type: research

Alcohol Hangover Has Detrimental Impact Upon Both Executive Function and Prospective Memory
The alcohol-hangover (AH) is a state of general malaise following an evening of heavy episodic drinking when the blood alcohol concentration of the person reaches/approaches zero. The aim of the current study was to investigate what impact the AH has upon both executive function (EF) and prospective memory (PM). Previous research has shown that the AH has a detrimental effect upon cognitive abilities, including attention, working memory and prospective memory. The current study focused upon what impact AH might have upon both EF and related PM in the same cohort, both of which underpin everyday remembering. The current stu...
Source: Frontiers in Psychiatry - May 16, 2019 Category: Psychiatry Source Type: research

A Review of Oenanthe javanica (Blume) DC. as Traditional Medicinal Plant and Its Therapeutic Potential.
Authors: Lu CL, Li XF Abstract Oenanthe javanica, popularly known as water dropwort, has long been used in various ethnomedical systems in Asia, especially in China, Korean, and Japan, for treating various chronic and acute hepatitis, jaundice, alcohol hangovers, abdominal pain, and inflammatory conditions. The present review aims to provide a general report of the available literature on traditional uses, phytochemical, pharmacological, nutritional, and toxicological data related to the O. javanica as a potential source of new compounds with biological activities. Considering phytochemical studies, coumarins, flav...
Source: Evidence-based Complementary and Alternative Medicine - May 8, 2019 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Zeolites as Carriers of Antitumor Ribonuclease Binase
In this study we tested the clinoptilolite, chabazite, and natrolite ability to be loaded by antitumor ribonuclease binase and the cytotoxicity of the obtained complexes. We found the optimal conditions for binase loading into zeolites and established the dynamic of its release. Cytotoxic effects of zeolite-binase complexes toward colorectal cancer Caco2 cells were characterized after 24 and 48 h of incubation with cells using MTT-test. Zeolites were toxic by itselfs and reduced cells viability by 30% (clinoptilolite), 40% (chabazite), and 70% (natrolite) after 48 h of incubation. Binase complexes with clinoptilolite as we...
Source: Frontiers in Pharmacology - May 2, 2019 Category: Drugs & Pharmacology Source Type: research

Effects of Phyllanthus amarus PHYLLPROTM leaves on hangover symptoms: a randomized, double-blind, placebo-controlled crossover study.
This study evaluated PHYLLPRO™, a standardized ethanol extract of P. amarus leaves for protection against oxidative stress and recovery from hangover symptoms. MATERIAL AND METHODS: Ten days daily oral supplementation of 750 mg/day followed by intoxication was evaluated in a randomized placebo-controlled (containing only excipient), crossover study in 15 subjects (21-50 years old), for oxidative stress, liver damage, alleviating hangover symptoms (Hangover Severity Score: HSS) and mood improvement (Profile-of-Mood-Scores: POMS). RESULTS: PHYLLPRO™ was able to remove blood alcohol in the ac...
Source: Pharmaceutical Biology - March 31, 2019 Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research

An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative review
In this study, we reviewed the relationship between the inducing diuresis effect of ORS and aquaporin, conservative treatment approach in patients with CSDH, and the prevention of recurrence in patients undergoing combined burr hole surgery and treatment with ORS. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - March 21, 2019 Category: Complementary Medicine Source Type: research

Risk Behaviors Associated with Alcohol Consumption Predict Future Severe Liver Disease
ConclusionsCertain risk behaviors can identify young men with a high risk of developing severe liver disease. Wine consumption was not associated with a reduced risk for severe liver disease compared to beer and spirits. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 14, 2019 Category: Gastroenterology Source Type: research

Beer before wine or wine before beer: the hangover is the same
Forget folk wisdom — mixing drinks doesn't affect your hangover. Only the amount you consume appears to impact how you feel the following day (Source: New Scientist - Health)
Source: New Scientist - Health - February 8, 2019 Category: Consumer Health News Source Type: research

Grape or grain but never the twain? A randomized controlled multiarm matched-triplet crossover trial of beer and wine.
Conclusions: Our findings dispel the traditional myths "Grape or grain but never the twain" and "Beer before wine and you'll feel fine; wine before beer and you'll feel queer" regarding moderate-to-severe alcohol intoxication, whereas subjective signs of progressive intoxication were confirmed as accurate predictors of hangover severity. This trial was prospectively registered at the Witten/Herdecke University Ethics Committee as 140/2016 and retrospectively registered at the German Clinical Trials Register as DRKS00015285. PMID: 30753321 [PubMed - in process] (Source: Am J Clin Nutr)
Source: Am J Clin Nutr - February 1, 2019 Category: Nutrition Authors: Köchling J, Geis B, Wirth S, Hensel KO Tags: Am J Clin Nutr Source Type: research

Hung over: What science says about why you feel so rough
Hair of the dog? Wine before beer? Why everything you know about hangovers, and how to cure them, is wrong – or unproven (Source: New Scientist - Health)
Source: New Scientist - Health - December 1, 2018 Category: Consumer Health News Source Type: research

Hangover follows extroverts: Extraversion as a moderator in the curvilinear relationship between newcomers' organizational tenure and job satisfaction
Publication date: February 2019Source: Journal of Vocational Behavior, Volume 110, Part AAuthor(s): Jooyeon Son, Chiho OkAbstractThe present study examines the nonlinear relationship between organizational tenure of and job satisfaction among new employees (i.e., newcomers). In particular, a newcomer's job satisfaction is described as a U-shaped curve that decreases after joining but increases after some time. Moreover, it predicts that this temporal change in job satisfaction differs depending on a newcomer's extraversion. Analyzing five-wave unbalanced panel data for 1553 individuals and 5770 observations in South Korea,...
Source: Journal of Vocational Behavior - November 29, 2018 Category: Psychiatry & Psychology Source Type: research

Oreongsan, an herbal medicine prescription developed as a new alternative treatment in patients with chronic subdural hematoma: A narrative review
In this study, we reviewed the relationship between the isu effect of ORS and aquaporin, conservative treatment approach in patients with CSDH, and the prevention of recurrence in patients undergoing combined burr hole surgery and treatment with ORS. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 25, 2018 Category: Complementary Medicine Source Type: research

Extraversion as a moderator in the curvilinear relationship between newcomers' organizational tenure and job satisfaction
Publication date: Available online 9 November 2018Source: Journal of Vocational BehaviorAuthor(s): Jooyeon Son, Chiho OkAbstractThe present study examines the nonlinear relationship between organizational tenure of and job satisfaction among new employees (i.e., newcomers). In particular, a newcomer's job satisfaction is described as a U-shaped curve that decreases after joining but increases after some time. Moreover, it predicts that this temporal change in job satisfaction differs depending on a newcomer's extraversion. Analyzing five-wave unbalanced panel data for 1553 individuals and 5770 observations in South Korea, ...
Source: Journal of Vocational Behavior - November 9, 2018 Category: Psychiatry & Psychology Source Type: research

Shyness, alcohol use disorders and ‘hangxiety’: A naturalistic study of social drinkers
This study suggests anxiety during hangover is linked to AUD symptoms in highly-shy individuals, providing a potential marker for increased AUD risk, which could inform prevention and treatment. (Source: Personality and Individual Differences)
Source: Personality and Individual Differences - November 6, 2018 Category: Psychiatry & Psychology Source Type: research

The impact of expectancy on cognitive performance during alcohol hangover
Knowing the purpose of a clinical study may provoke expectancies among subjects that may influence the study outcome. For example, expectancies about a drug effect may cause subjects to put in more effort to c... (Source: BMC Research Notes)
Source: BMC Research Notes - October 18, 2018 Category: Research Authors: Lydia E. Devenney, Kieran B. Coyle and Joris C. Verster Tags: Research note Source Type: research

The flavonoid acetylpectolinarin counteracts the effects of low ethanol on spontaneous network activity in hippocampal cultures
ConclusionsOur results suggest that ACP acts by interacting with the SK channel, to block the facilitatory effect of low concentration of ethanol, on network activity in hippocampal cultures.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - October 5, 2018 Category: Drugs & Pharmacology Source Type: research

A State of Alcohol Hangover Impedes Everyday Prospective Memory
Thomas Heffernan (Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - September 19, 2018 Category: Neuroscience Source Type: research

Alcohol Hangover Increases Conflict Load via Faster Processing of Subliminal Information
Nicolas Zink, Wiebke Bensmann, Christian Beste, Ann-Kathrin Stock (Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - August 21, 2018 Category: Neuroscience Source Type: research

[Melatonin: Physiological and pharmacological aspects related to sleep: The interest of a prolonged-release formulation (Circadin ®) in insomnia].
[Melatonin: Physiological and pharmacological aspects related to sleep: The interest of a prolonged-release formulation (Circadin®) in insomnia]. Encephale. 2018 Aug 11;: Authors: Quera-Salva MA, Claustrat B Abstract Melatonin is a hormone secreted by the pineal gland. It displays a very marked nycthohemeral rhythm, which is entrained to the light dark cycle. The secretion spreads over 8-10 hours, with a maximum around 3-4 a.m. Melatonin plays the role of an endogenous synchronizer which regulates circadian rhythms, especially the sleep/wake and temperature rhythms. Acute melatonin administrat...
Source: L Encephale - August 17, 2018 Category: Psychiatry Tags: Encephale Source Type: research

What Reminds Young People That They Drank More Than Intended on Weekend Nights: An Event-Level Study.
CONCLUSIONS: Young people not only tend to drink more than intended on weekend nights but also often fail to acknowledge this the next morning. Event based prevention measures aimed at narrowing the gap between drinking intentions and quantities of alcohol consumed are recommended. PMID: 30079881 [PubMed - in process] (Source: Journal of Studies on Alcohol and Drugs)
Source: Journal of Studies on Alcohol and Drugs - August 11, 2018 Category: Addiction Tags: J Stud Alcohol Drugs Source Type: research

Pharmacological manipulation of the ghrelin system and alcohol hangover symptoms in heavy drinking individuals: Is there a link?
Publication date: Available online 17 July 2018Source: Pharmacology Biochemistry and BehaviorAuthor(s): Mehdi Farokhnia, Mary R. Lee, Lisa A. Farinelli, Vijay A. Ramchandani, Fatemeh Akhlaghi, Lorenzo LeggioAbstractGhrelin, an orexigenic peptide synthesized in the stomach, is a key player in the gut-brain axis. In addition to its role in regulating food intake and energy homeostasis, ghrelin has been shown to modulate alcohol-related behaviors. Alcohol consumption frequently results in hangover, an underexplored phenomenon with considerable medical, psychological, and socioeconomic consequences. While the pathophysiology o...
Source: Pharmacology Biochemistry and Behavior - July 18, 2018 Category: Biochemistry Source Type: research

Romantic relationships, college student alcohol use, and negative consequences of drinking
This study examined whether being in a romantic relationship is associated with undergraduates’ alcohol use and negative consequences of drinking. Alcohol use was operationalized to include amount and frequency of drinking, binge drinking, and drunkenness. Negative consequences included: having a hangover, missing a class, getting behind in school work, doing something that was later regretted, forgetting where the student was or what they did, having unplanned sex, and getting hurt or injured. Data came from an online survey distributed to Midwestern undergraduate students (N = 572), with analyses conducte...
Source: The Social Science Journal - July 10, 2018 Category: Psychiatry & Psychology Source Type: research