ZBiotics raises funds for hangover probiotic
(Source: Chemical and Engineering News)
Source: Chemical and Engineering News - March 21, 2020 Category: Chemistry Authors: Ryan Cross Source Type: research

Effect of single-dose, oral enzymatic porcine placental extract(EPPE) on pharmacokinetics of alcohol and liver function in rats.
CONCLUSIONS: The single-dose EPPE (0.5~2.5 g/kg) suppressed absorption of alcohol in the gastrointestinal tract. This may be useful in preventing hangover effects and toxicity after drinking alcohol and may also preserve liver health after alcohol ingestion. PMID: 32154587 [PubMed - as supplied by publisher] (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - March 10, 2020 Category: Addiction Authors: Kim HJ, Kim S, Seo JS, Bae GW, Kim KN, Kang JS Tags: Alcohol Clin Exp Res Source Type: research

Optimization of Protoplast Preparation and Regeneration of a Medicinal Fungus Antrodia cinnamomea.
Authors: Wu JD, Chou JC Abstract Antrodia cinnamomea is a unique medicinal fungus in Taiwan. It has been found rich in some pharmacologically active compounds for anti-cancer, hangover, and immune regulation etc. With the in-depth study of these components, it would be interesting and important to establish a molecular system for basic studies of A. cinnamomea. Thus, we would like to set up a foundation for this purpose by studying the A. cinnamomea protoplast preparation and regeneration. Firstly, we studied the optimization method of protoplast preparation of A. cinnamomea, and found various factors that may affe...
Source: Mycobiology - February 7, 2020 Category: Biology Tags: Mycobiology Source Type: research

Honeymoon or hangover? How election outcomes produce emotional shifts to winning candidate smiles
This study examines changes in self-reported happiness, anger, and distress to different smile types expressed by Barack Obama and Mitt Romney, measured immediately prior to and again following the 2012 presidential election. A panel of online respondents (N = 214) were shown four video clips featuring different smile types from each candidate before and after the election. Obama's clips featured an amusement and controlled-amusement smile, while Romney's featured a posed and contempt smiles. Findings revealed significant differences in self-reported emotional response to Obama. Followers of Obama reported an increase ...
Source: Personality and Individual Differences - September 27, 2019 Category: Psychiatry & Psychology Source Type: research

Event-level correlates of drinking events characterized by alcohol-induced blackouts.
CONCLUSIONS: Event-level findings of this study document that events leading to alcohol-induced memory loss are associated with other adverse experiences relative to drinking events that do not result in blackout, and offer potentially motivational levers for preventive interventions. PMID: 31557348 [PubMed - as supplied by publisher] (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - September 26, 2019 Category: Addiction Authors: Merrill JE, Boyle HK, Jackson KM, Carey KB Tags: Alcohol Clin Exp Res Source Type: research

Exploring the emotional experiences of alcohol hangover syndrome in healthy UK-based adults
. (Source: Drugs: Education, Prevention, and Policy)
Source: Drugs: Education, Prevention, and Policy - August 27, 2019 Category: Addiction Authors: Ian James Milton Elizabeth Sillence Melanie Mitchell Source Type: research

The world's first GMO probiotic is for sale; it's designed to prevent hangovers
The product, made by ZBiotics, is regulated as a food, not a drug, and has not been formally vetted for effectiveness in humans (Source: Chemical and Engineering News)
Source: Chemical and Engineering News - August 21, 2019 Category: Chemistry Authors: Ryan Cross Source Type: research

The first GMO probiotic is for sale; it's designed to prevent hangovers
The product, made by ZBiotics, is regulated as a supplement, not a drug, and has not been vetted for effectiveness in humans (Source: Chemical and Engineering News)
Source: Chemical and Engineering News - August 19, 2019 Category: Chemistry Authors: Ryan Cross Source Type: research

The world's first GMO probiotic is for sale; it's designed to prevent hangovers
The product, made by ZBiotics, is regulated as a food, not a drug, and has not been vetted for effectiveness in humans (Source: Chemical and Engineering News)
Source: Chemical and Engineering News - August 19, 2019 Category: Chemistry Authors: Ryan Cross Source Type: research

Dihydromyricetin: A review on identification and quantification methods, biological activities, chemical stability, metabolism and approaches to enhance its bioavailability
Publication date: Available online 25 July 2019Source: Trends in Food Science & TechnologyAuthor(s): Dan Liu, Yiqin Mao, Lijun Ding, Xin-An ZengAbstractBackgroundDihydromyricetin (DMY) is an important plant flavonoid, which has received great attention due to its health-benefiting, including antioxidant, antimicrobial, anti-inflammatory, anticancer, antidiabetic and neuroprotective activities. DMY capsules have been sold in US as a nutraceutical supplement to prevent alcoholic hangovers. The major disadvantage associated with DMY is its chemical instability and poor bioavailability caused by the combined effects of its...
Source: Trends in Food Science and Technology - July 27, 2019 Category: Food Science Source Type: research

Social and Situational Party Characteristics Associated With High-Intensity Alcohol Use Among Youth and Young Adults.
CONCLUSIONS: Results from this study indicate there are unique precursors and consequences of high-intensity alcohol consumption among youth and young adults. These environmental factors associated with high-risk drinking contexts can be used to develop prevention strategies to mitigate the harms associated with excessive alcohol consumption. PMID: 31313331 [PubMed - as supplied by publisher] (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - July 16, 2019 Category: Addiction Authors: Cox MJ, Egan KL, Suerken CK, Reboussin BA, Song EY, Wagoner KG, Wolfson M Tags: Alcohol Clin Exp Res Source Type: research

Alcohol Hangover Has Detrimental Impact Upon Both Executive Function and Prospective Memory
The alcohol-hangover (AH) is a state of general malaise following an evening of heavy episodic drinking when the blood alcohol concentration of the person reaches/approaches zero. The aim of the current study was to investigate what impact the AH has upon both executive function (EF) and prospective memory (PM). Previous research has shown that the AH has a detrimental effect upon cognitive abilities, including attention, working memory and prospective memory. The current study focused upon what impact AH might have upon both EF and related PM in the same cohort, both of which underpin everyday remembering. The current stu...
Source: Frontiers in Psychiatry - May 17, 2019 Category: Psychiatry Source Type: research

A Review of Oenanthe javanica (Blume) DC. as Traditional Medicinal Plant and Its Therapeutic Potential.
Authors: Lu CL, Li XF Abstract Oenanthe javanica, popularly known as water dropwort, has long been used in various ethnomedical systems in Asia, especially in China, Korean, and Japan, for treating various chronic and acute hepatitis, jaundice, alcohol hangovers, abdominal pain, and inflammatory conditions. The present review aims to provide a general report of the available literature on traditional uses, phytochemical, pharmacological, nutritional, and toxicological data related to the O. javanica as a potential source of new compounds with biological activities. Considering phytochemical studies, coumarins, flav...
Source: Evidence-based Complementary and Alternative Medicine - May 8, 2019 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Zeolites as Carriers of Antitumor Ribonuclease Binase
In this study we tested the clinoptilolite, chabazite, and natrolite ability to be loaded by antitumor ribonuclease binase and the cytotoxicity of the obtained complexes. We found the optimal conditions for binase loading into zeolites and established the dynamic of its release. Cytotoxic effects of zeolite-binase complexes toward colorectal cancer Caco2 cells were characterized after 24 and 48 h of incubation with cells using MTT-test. Zeolites were toxic by itselfs and reduced cells viability by 30% (clinoptilolite), 40% (chabazite), and 70% (natrolite) after 48 h of incubation. Binase complexes with clinoptilolite as we...
Source: Frontiers in Pharmacology - May 3, 2019 Category: Drugs & Pharmacology Source Type: research

Effects of Phyllanthus amarus PHYLLPROTM leaves on hangover symptoms: a randomized, double-blind, placebo-controlled crossover study.
This study evaluated PHYLLPRO™, a standardized ethanol extract of P. amarus leaves for protection against oxidative stress and recovery from hangover symptoms. MATERIAL AND METHODS: Ten days daily oral supplementation of 750 mg/day followed by intoxication was evaluated in a randomized placebo-controlled (containing only excipient), crossover study in 15 subjects (21-50 years old), for oxidative stress, liver damage, alleviating hangover symptoms (Hangover Severity Score: HSS) and mood improvement (Profile-of-Mood-Scores: POMS). RESULTS: PHYLLPRO™ was able to remove blood alcohol in the ac...
Source: Pharmaceutical Biology - March 31, 2019 Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research

An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative review
In this study, we reviewed the relationship between the inducing diuresis effect of ORS and aquaporin, conservative treatment approach in patients with CSDH, and the prevention of recurrence in patients undergoing combined burr hole surgery and treatment with ORS. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - March 22, 2019 Category: Complementary Medicine Source Type: research

Risk Behaviors Associated with Alcohol Consumption Predict Future Severe Liver Disease
ConclusionsCertain risk behaviors can identify young men with a high risk of developing severe liver disease. Wine consumption was not associated with a reduced risk for severe liver disease compared to beer and spirits. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 14, 2019 Category: Gastroenterology Source Type: research

Beer before wine or wine before beer: the hangover is the same
Forget folk wisdom — mixing drinks doesn't affect your hangover. Only the amount you consume appears to impact how you feel the following day (Source: New Scientist - Health)
Source: New Scientist - Health - February 8, 2019 Category: Consumer Health News Source Type: research

Grape or grain but never the twain? A randomized controlled multiarm matched-triplet crossover trial of beer and wine.
Conclusions: Our findings dispel the traditional myths "Grape or grain but never the twain" and "Beer before wine and you'll feel fine; wine before beer and you'll feel queer" regarding moderate-to-severe alcohol intoxication, whereas subjective signs of progressive intoxication were confirmed as accurate predictors of hangover severity. This trial was prospectively registered at the Witten/Herdecke University Ethics Committee as 140/2016 and retrospectively registered at the German Clinical Trials Register as DRKS00015285. PMID: 30753321 [PubMed - in process] (Source: Am J Clin Nutr)
Source: Am J Clin Nutr - February 1, 2019 Category: Nutrition Authors: Köchling J, Geis B, Wirth S, Hensel KO Tags: Am J Clin Nutr Source Type: research

Hung over: What science says about why you feel so rough
Hair of the dog? Wine before beer? Why everything you know about hangovers, and how to cure them, is wrong – or unproven (Source: New Scientist - Health)
Source: New Scientist - Health - December 1, 2018 Category: Consumer Health News Source Type: research

Hangover follows extroverts: Extraversion as a moderator in the curvilinear relationship between newcomers' organizational tenure and job satisfaction
Publication date: February 2019Source: Journal of Vocational Behavior, Volume 110, Part AAuthor(s): Jooyeon Son, Chiho OkAbstractThe present study examines the nonlinear relationship between organizational tenure of and job satisfaction among new employees (i.e., newcomers). In particular, a newcomer's job satisfaction is described as a U-shaped curve that decreases after joining but increases after some time. Moreover, it predicts that this temporal change in job satisfaction differs depending on a newcomer's extraversion. Analyzing five-wave unbalanced panel data for 1553 individuals and 5770 observations in South Korea,...
Source: Journal of Vocational Behavior - November 29, 2018 Category: Psychiatry & Psychology Source Type: research

Oreongsan, an herbal medicine prescription developed as a new alternative treatment in patients with chronic subdural hematoma: A narrative review
In this study, we reviewed the relationship between the isu effect of ORS and aquaporin, conservative treatment approach in patients with CSDH, and the prevention of recurrence in patients undergoing combined burr hole surgery and treatment with ORS. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 25, 2018 Category: Complementary Medicine Source Type: research

Extraversion as a moderator in the curvilinear relationship between newcomers' organizational tenure and job satisfaction
Publication date: Available online 9 November 2018Source: Journal of Vocational BehaviorAuthor(s): Jooyeon Son, Chiho OkAbstractThe present study examines the nonlinear relationship between organizational tenure of and job satisfaction among new employees (i.e., newcomers). In particular, a newcomer's job satisfaction is described as a U-shaped curve that decreases after joining but increases after some time. Moreover, it predicts that this temporal change in job satisfaction differs depending on a newcomer's extraversion. Analyzing five-wave unbalanced panel data for 1553 individuals and 5770 observations in South Korea, ...
Source: Journal of Vocational Behavior - November 9, 2018 Category: Psychiatry & Psychology Source Type: research

Shyness, alcohol use disorders and ‘hangxiety’: A naturalistic study of social drinkers
This study suggests anxiety during hangover is linked to AUD symptoms in highly-shy individuals, providing a potential marker for increased AUD risk, which could inform prevention and treatment. (Source: Personality and Individual Differences)
Source: Personality and Individual Differences - November 6, 2018 Category: Psychiatry & Psychology Source Type: research

The impact of expectancy on cognitive performance during alcohol hangover
Knowing the purpose of a clinical study may provoke expectancies among subjects that may influence the study outcome. For example, expectancies about a drug effect may cause subjects to put in more effort to c... (Source: BMC Research Notes)
Source: BMC Research Notes - October 18, 2018 Category: Research Authors: Lydia E. Devenney, Kieran B. Coyle and Joris C. Verster Tags: Research note Source Type: research

The flavonoid acetylpectolinarin counteracts the effects of low ethanol on spontaneous network activity in hippocampal cultures
ConclusionsOur results suggest that ACP acts by interacting with the SK channel, to block the facilitatory effect of low concentration of ethanol, on network activity in hippocampal cultures.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - October 5, 2018 Category: Drugs & Pharmacology Source Type: research

A State of Alcohol Hangover Impedes Everyday Prospective Memory
Thomas Heffernan (Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - September 19, 2018 Category: Neuroscience Source Type: research

Alcohol Hangover Increases Conflict Load via Faster Processing of Subliminal Information
Nicolas Zink, Wiebke Bensmann, Christian Beste, Ann-Kathrin Stock (Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - August 21, 2018 Category: Neuroscience Source Type: research

[Melatonin: Physiological and pharmacological aspects related to sleep: The interest of a prolonged-release formulation (Circadin ®) in insomnia].
[Melatonin: Physiological and pharmacological aspects related to sleep: The interest of a prolonged-release formulation (Circadin®) in insomnia]. Encephale. 2018 Aug 11;: Authors: Quera-Salva MA, Claustrat B Abstract Melatonin is a hormone secreted by the pineal gland. It displays a very marked nycthohemeral rhythm, which is entrained to the light dark cycle. The secretion spreads over 8-10 hours, with a maximum around 3-4 a.m. Melatonin plays the role of an endogenous synchronizer which regulates circadian rhythms, especially the sleep/wake and temperature rhythms. Acute melatonin administrat...
Source: L Encephale - August 17, 2018 Category: Psychiatry Tags: Encephale Source Type: research

What Reminds Young People That They Drank More Than Intended on Weekend Nights: An Event-Level Study.
CONCLUSIONS: Young people not only tend to drink more than intended on weekend nights but also often fail to acknowledge this the next morning. Event based prevention measures aimed at narrowing the gap between drinking intentions and quantities of alcohol consumed are recommended. PMID: 30079881 [PubMed - in process] (Source: Journal of Studies on Alcohol and Drugs)
Source: Journal of Studies on Alcohol and Drugs - August 11, 2018 Category: Addiction Tags: J Stud Alcohol Drugs Source Type: research

Pharmacological manipulation of the ghrelin system and alcohol hangover symptoms in heavy drinking individuals: Is there a link?
Publication date: Available online 17 July 2018Source: Pharmacology Biochemistry and BehaviorAuthor(s): Mehdi Farokhnia, Mary R. Lee, Lisa A. Farinelli, Vijay A. Ramchandani, Fatemeh Akhlaghi, Lorenzo LeggioAbstractGhrelin, an orexigenic peptide synthesized in the stomach, is a key player in the gut-brain axis. In addition to its role in regulating food intake and energy homeostasis, ghrelin has been shown to modulate alcohol-related behaviors. Alcohol consumption frequently results in hangover, an underexplored phenomenon with considerable medical, psychological, and socioeconomic consequences. While the pathophysiology o...
Source: Pharmacology Biochemistry and Behavior - July 18, 2018 Category: Biochemistry Source Type: research

Romantic relationships, college student alcohol use, and negative consequences of drinking
This study examined whether being in a romantic relationship is associated with undergraduates’ alcohol use and negative consequences of drinking. Alcohol use was operationalized to include amount and frequency of drinking, binge drinking, and drunkenness. Negative consequences included: having a hangover, missing a class, getting behind in school work, doing something that was later regretted, forgetting where the student was or what they did, having unplanned sex, and getting hurt or injured. Data came from an online survey distributed to Midwestern undergraduate students (N = 572), with analyses conducte...
Source: The Social Science Journal - July 11, 2018 Category: Psychiatry & Psychology Source Type: research

IJERPH, Vol. 15, Pages 1286: Susceptibility to Alcohol Hangovers: The Association with Self-Reported Immune Status
In conclusion, experiencing alcohol hangovers is associated with significantly poorer self-reported immune function. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - June 18, 2018 Category: Environmental Health Authors: Aurora J. A. E. van de Loo Marlou Mackus Marith van Schrojenstein Lantman Aletta D. Kraneveld Karel A. Brookhuis Johan Garssen Andrew Scholey Joris C. Verster Tags: Article Source Type: research

Red mulberry fruit aqueous extract and silk proteins accelerate acute ethanol metabolism and promote the anti ‑oxidant enzyme systems in rats.
In conclusions, both WMB and SKA might reduce acute alcohol‑induced hangover and liver and brain damage by lowering serum alcohol and acetaldehyde levels. PMID: 29767238 [PubMed - as supplied by publisher] (Source: Molecular Medicine Reports)
Source: Molecular Medicine Reports - May 18, 2018 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Hangover in Post ‐College‐Aged Drinkers: Psychometric Properties of the Hangover Symptom Scale (HSS) and the Hangover Symptom Scale—Short Form (HSS‐5)
Alcoholism: Clinical and Experimental Research, EarlyView. (Source: Alcoholism: Clinical and Experimental Research)
Source: Alcoholism: Clinical and Experimental Research - April 16, 2018 Category: Addiction Authors: Jesus Chavarria , Sandra Y. Rueger , Andrea C. King Source Type: research

Hangover in Post-College-Aged Drinkers: Psychometric Properties of the Hangover Symptom Scale (HSS) and the Hangover Symptom Scale-Short Form (HSS-5).
CONCLUSIONS: This was the first study to examine the psychometric properties of the HSS and HSS-5 in a post-college-aged sample and the first to investigate the measurement invariance of these measures as a function of sex, drinking history, and family history of AUD. This study supports the use of the HSS-5 as a reliable and valid brief measure of frequency of hangover symptoms. PMID: 29660151 [PubMed - as supplied by publisher] (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - April 16, 2018 Category: Addiction Authors: Chavarria J, Rueger SY, King AC Tags: Alcohol Clin Exp Res Source Type: research

Hangover in Post ‐College‐Aged Drinkers: Psychometric Properties of the Hangover Symptom Scale (HSS) and the Hangover Symptom Scale—Short Form (HSS‐5)
Alcoholism: Clinical and Experimental Research, EarlyView. (Source: Alcoholism: Clinical and Experimental Research)
Source: Alcoholism: Clinical and Experimental Research - April 16, 2018 Category: Addiction Authors: Jesus Chavarria , Sandra Y. Rueger , Andrea C. King Source Type: research

Bioactivities of decoctions from Plectranthus species related to their traditional use on the treatment of digestive problems and alcohol intoxication
Conclusions All activities presented by the RA-rich Plectranthus decoctions support their use in treating digestion disorders and P. barbatus could explain its use also for alleviating hangover symptoms. Medioresinol, which is present in P. zuluensis, exhibited a significant AChE inhibition and may provide, in the future, a new lead for bioactive compounds. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - April 10, 2018 Category: Drugs & Pharmacology Source Type: research

Ocular hangover
Emergency Medicine Australasia, EarlyView. (Source: Emergency Medicine Australasia)
Source: Emergency Medicine Australasia - April 2, 2018 Category: Emergency Medicine Authors: Cam Loveridge ‐Easther , Sacha Moore Source Type: research

Alcohol hangover impacts learning and reward processing within the medial ‐frontal cortex
Psychophysiology, EarlyView. (Source: Psychophysiology)
Source: Psychophysiology - March 30, 2018 Category: Neurology Source Type: research

‘All suffering together’: student drinkers’ experiences of alcohol hangover
. (Source: Addiction Research and Theory)
Source: Addiction Research and Theory - March 21, 2018 Category: Addiction Authors: Christine Griffin Madeleine Freeman Sally Adams Paula Smith Source Type: research

Romantic relationships, college student alcohol use, and negative consequences of drinking
This study examined whether being in a romantic relationship is associated with undergraduates’ alcohol use and negative consequences of drinking. Alcohol use was operationalized to include amount and frequency of drinking, binge drinking, and drunkenness. Negative consequences included: having a hangover, missing a class, getting behind in school work, doing something that was later regretted, forgetting where the student was or what they did, having unplanned sex, and getting hurt or injured. Data came from an online survey distributed to Midwestern undergraduate students (N =572), with analyses conducted separatel...
Source: The Social Science Journal - March 15, 2018 Category: Psychiatry & Psychology Source Type: research

Differences in the Temporal Typology of Alcohol Hangover
Alcoholism: Clinical and Experimental Research, EarlyView. (Source: Alcoholism: Clinical and Experimental Research)
Source: Alcoholism: Clinical and Experimental Research - February 27, 2018 Category: Addiction Source Type: research

Alcohol metabolism in hangover sensitive versus hangover resistant social drinkers
(Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - February 21, 2018 Category: Addiction Authors: M. Mackus, M. van Schrojenstein Lantman, A.J.A.E. Van de Loo, A.D. Kraneveld, J. Garssen, K.A. Brookhuis, J.C. Verster Source Type: research