Heart Rate Variability as a Prognostic Tool for Gastroschisis Infants in the Neonatal Intensive Critical Unit
Conclusion Decreased HRV was associated with complex gastroschisis. Infants in this group experienced complications that prolonged time to full enteral feeding and time on total parenteral nutrition. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - February 28, 2024 Category: Perinatology & Neonatology Authors: Moneme, Chioma Kausch, Sherry L. Belmonte, Briana M. Fleming II, Mark A. Levin, Daniel E. Sullivan, Brynne A. Tags: Original Article Source Type: research

Reassessing acquired neonatal intestinal diseases using unsupervised machine learning
CONCLUSION: Unsupervised machine learning can be used to cluster acquired neonatal intestinal injuries. Future study with larger multicenter datasets is needed to further refine and classify types of intestinal diseases.IMPACT: Unsupervised machine learning can be used to cluster types of acquired neonatal intestinal injury. Five major clusters of acquired neonatal intestinal injury are described, each with unique features. The clusters herein described deserve future, multicenter study to determine more specific early biomarkers and tailored therapeutic interventions to improve outcomes of often devastating neonatal acqui...
Source: Pediatric Research - February 27, 2024 Category: Pediatrics Authors: Daniel R Gipson Alan L Chang Allison C Lure Sonia A Mehta Taylor Gowen Erin Shumans David Stevenson Diomel de la Cruz Nima Aghaeepour Josef Neu Source Type: research

Reassessing acquired neonatal intestinal diseases using unsupervised machine learning
CONCLUSION: Unsupervised machine learning can be used to cluster acquired neonatal intestinal injuries. Future study with larger multicenter datasets is needed to further refine and classify types of intestinal diseases.IMPACT: Unsupervised machine learning can be used to cluster types of acquired neonatal intestinal injury. Five major clusters of acquired neonatal intestinal injury are described, each with unique features. The clusters herein described deserve future, multicenter study to determine more specific early biomarkers and tailored therapeutic interventions to improve outcomes of often devastating neonatal acqui...
Source: Pediatric Research - February 27, 2024 Category: Pediatrics Authors: Daniel R Gipson Alan L Chang Allison C Lure Sonia A Mehta Taylor Gowen Erin Shumans David Stevenson Diomel de la Cruz Nima Aghaeepour Josef Neu Source Type: research

European reference network for rare inherited congenital anomalies (ERNICA) evidence based guideline on the management of gastroschisis
The European Reference Network for rare Inherited Congenital Anomalies, ERNICA, guidelines for gastroschisis cover perinatal period to help teams to improve care. (Source: Orphanet Journal of Rare Diseases)
Source: Orphanet Journal of Rare Diseases - February 12, 2024 Category: Internal Medicine Authors: Carmen Mesas Burgos, Willemijn Irvine, Alexandre Vivanti, Peter Conner, Egle Machtejeviene, Nina Peters, Joan Sabria, Ana Sanchez Torres, Costanza Tognon, Alberto Sgr ó, Antti Kouvisalo, Hester Langeveld-Benders, Rony Sfeir, Marc Miserez, Nils Qvist, Aus Tags: Review Source Type: research

Association of Exclusive Breast Milk Intake and Outcomes in Infants with Uncomplicated Gastroschisis: A National Cohort Study
Enteral feeding is an essential part of the management of infants with gastroschisis. We hypothesized that exclusive breast milk is associated with improved neonatal outcomes. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - February 3, 2024 Category: Surgery Authors: Emily Hodgson, Daniel Briatico, Sarah Klapman, Erik Skarsgard, Marc Beltempo, Prakesh S. Shah, Esther Huisman, J. Mark Walton, Michael H. Livingston, Canadian Association of Pediatric Surgeons Network (CAPSNet) and Canadian Neonatal Network (CNN) investig Source Type: research

Evaluating prenatal ultrasonographic predictors of complex gastroschisis
Background: Gastroschisis is a congenital anterior abdominal wall defect where herniated abdominal visceral contents are present. It is usually isolated, not associated with other congenital anomalies nor any risk of aneuploidy. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2024 Category: OBGYN Authors: Iftene Lavinia, Veronique Debarge-Houfflin Source Type: research

Medication use during pregnancy and the risk of gastroschisis: a systematic review and meta-analysis of observational studies
The aetiology of gastroschisis is considered multifactorial. We conducted a systematic review and meta-analysis to assess whether the use of medications during pregnancy, is associated with the risk of gastros... (Source: Orphanet Journal of Rare Diseases)
Source: Orphanet Journal of Rare Diseases - January 30, 2024 Category: Internal Medicine Authors: Silvia Baldacci, Michele Santoro, Lorena Mezzasalma, Anna Pierini and Alessio Coi Tags: Review Source Type: research

Letter to the Editor regarding: Immediate versus delayed surgical management of cryptorchidism in newborns with gastroschisis
The authors declare no competing interests. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - January 24, 2024 Category: Surgery Authors: Denis A. Cozzi, Silvia Ceccanti Source Type: research

Letter to the Editor in response to: Immediate Versus Delayed Surgical Management of Cryptorchidism in Newborns With Gastroschisis
We read with interest the article by Ramsey and Colleagues entitled “Immediate versus delayed surgical management of infant cryptorchidism with inguinal hernia” [1]. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - January 24, 2024 Category: Surgery Authors: Denis A. Cozzi, Silvia Ceccanti Source Type: research

806 Validation of the fetal lamb model of complex gastroschisis
Despite perceived favorable outcomes, complex Gastroschisis (cGS) has a significant morbidity such as sepsis, necrotizing enterocolitis, short bowel syndrome and bowel obstruction. A realistic animal model is lacking to enable further investigation of the pathogenesis of bowel dysfunction and development of novel prenatal therapies. We aimed to develop and validate a fetal lamb model of cGS. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - January 1, 2024 Category: OBGYN Authors: Luc Joyeux, David Basurto, Kanokwaroon Watananirun, Tom Bleeser, Ignacio J. Valenzuela, Tomohiro Arai, Inge Depoortere, Alison Accarie, Tim Vanuystel, Michael Aertsen, Alex Menys, Paolo De Coppi, Larry H. Hollier, Michael A. Belfort, Jan Deprest, Sundeep Source Type: research

34 Safety and efficacy of open fetal repair of complex gastroschisis in the fetal lamb model
In utero repair of complex gastroschisis (cGS) may prevent progressive and irreversible bowel damage due to inflammation and ischemia. We aimed to assess the safety and efficacy of open fetal repair of cGS in a previously validated fetal lamb model. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - January 1, 2024 Category: OBGYN Authors: Luc Joyeux, David Basurto, Kanokwaroon Watananirun, Tom Bleeser, Tomohiro Arai, Inge Depoortere, Alison Accarie, Tim Vanuystel, Michael Aertsen, Alex Menys, Paolo De Coppi, Larry H. Hollier, Michael A. Belfort, Jan Deprest, Sundeep Keswani Tags: Oral Concurrent Session 3 - Basic Science Source Type: research

Hospital Variation in Mortality and Failure to Rescue after Surgery for High-Risk Neonatal Diagnoses
CONCLUSIONS: Significant variation in neonatal hospital mortality for high-risk diagnoses does not appear to be explained by hospital structural characteristics. Rather, difference in FTR suggests quality improvement interventions targeting early recognition and management of postoperative complications could improve surgical quality and safety for high-risk neonatal care.PMID:37844560 | DOI:10.1159/000533825 (Source: Neonatology)
Source: Neonatology - October 16, 2023 Category: Perinatology & Neonatology Authors: Steven C Mehl Jorge I Portuondo Yao Tian Mehul V Raval Alice King Kristy L Rialon Adam M Vogel David E Wesson Sohail R Shah Nader N Massarweh Source Type: research

Hospital Variation in Mortality and Failure to Rescue after Surgery for High-Risk Neonatal Diagnoses
CONCLUSIONS: Significant variation in neonatal hospital mortality for high-risk diagnoses does not appear to be explained by hospital structural characteristics. Rather, difference in FTR suggests quality improvement interventions targeting early recognition and management of postoperative complications could improve surgical quality and safety for high-risk neonatal care.PMID:37844560 | DOI:10.1159/000533825 (Source: Neonatology)
Source: Neonatology - October 16, 2023 Category: Perinatology & Neonatology Authors: Steven C Mehl Jorge I Portuondo Yao Tian Mehul V Raval Alice King Kristy L Rialon Adam M Vogel David E Wesson Sohail R Shah Nader N Massarweh Source Type: research

Major Congenital Anomalies in Korean Livebirths in 2013-2014: Based on the National Health Insurance Database
CONCLUSION: The proportion of surgeries, preterm births and mortality was high in infants with major congenital anomalies. The establishment of a national registry of congenital anomalies and systematic support by national medical policies are needed for infants with major congenital anomalies in Korea.PMID:37821084 | DOI:10.3346/jkms.2023.38.e304 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - October 11, 2023 Category: Biomedical Science Authors: Jin A Lee Soon Min Lee Sung-Hoon Chung Jang Hoon Lee Jae Won Shim Jae Woo Lim Chang-Ryul Kim Yun Sil Chang Source Type: research

Major Congenital Anomalies in Korean Livebirths in 2013-2014: Based on the National Health Insurance Database
CONCLUSION: The proportion of surgeries, preterm births and mortality was high in infants with major congenital anomalies. The establishment of a national registry of congenital anomalies and systematic support by national medical policies are needed for infants with major congenital anomalies in Korea.PMID:37821084 | PMC:PMC10562182 | DOI:10.3346/jkms.2023.38.e304 (Source: J Korean Med Sci)
Source: J Korean Med Sci - October 11, 2023 Category: General Medicine Authors: Jin A Lee Soon Min Lee Sung-Hoon Chung Jang Hoon Lee Jae Won Shim Jae Woo Lim Chang-Ryul Kim Yun Sil Chang Source Type: research