Free Living Amoebozoa Infection Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Microbial keratitis in Southern Malawi: a microbiological pilot study
CONCLUSIONS: In a resource-poor setting, a CIM can be used to safely sample the cornea in patients presenting with suspected MK, enabling identification of causative microorganisms by culture and PCR. Although the microbiological spectrum found was limited to the dry season, these preliminary results could be used to guide empirical treatment.PMID:38653537 | DOI:10.1136/bmjophth-2024-001682 (Source: Herpes)
Source: Herpes - April 23, 2024 Category: Infectious Diseases Authors: Tobi F Somerville Shaffi Mdala Thokozani Zungu Moira Gandiwa Rose Herbert Dean Everett Caroline E Corless Nicholas A V Beare Timothy Neal Malcolm J Horsburgh Alistair Darby Stephen B Kaye Petros C Kayange Source Type: research

Successful Treatment of Therapy-refractory Acanthamoeba Keratitis with Systemic Miltefosine and Topical Voriconazole
Klin Monbl Augenheilkd. 2024 Apr;241(4):406-408. doi: 10.1055/a-2196-6011. Epub 2024 Apr 23.NO ABSTRACTPMID:38653269 | DOI:10.1055/a-2196-6011 (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 23, 2024 Category: Opthalmology Authors: Petra Schwarzer Frank Blaser Miriam Sellner Stephan Christian Rauthe Tamer Tandogan Christoph Tappeiner David Goldblum Source Type: research

Anti-Acanthamoeba metallopharmaceuticals: Amoebicidal activity and synergistic effect of copper(II) coordination compound
This study evaluates the amoebicidal activity of copper(II) coordination compounds in combination with chlorhexidine and the cytotoxicity to topical ocular application. These copper(II) coordination compounds were screened against Acanthamoeba castellanii trophozoites (ATCC 50492). The cytotoxicity on rabbit corneal cell line (ATCC-CCL 60) was performed. The compounds showed high amoebicidal potential, with inhibition of trophozoite viability above 80%. The Cp12 and Cp13 compounds showed Minimal Inhibitory Amoebicidal Concentration (MIAC) at 200 µM and mean inhibitory concentration (IC50) values lower than 10 µM. Against...
Source: Biometals - April 22, 2024 Category: Biochemistry Authors: Jaqueline da Silveira Ana Paula Cardoso Christiane Fernandes Adolfo Horn Junior Gabriella da Rosa Monte Machado Karin Silva Caumo Source Type: research

First isolation of Acanthamoeba spp. in seawater from the southeast of Buenos Aires (SE, Argentina)
Rev Argent Microbiol. 2024 Apr 16:S0325-7541(24)00038-5. doi: 10.1016/j.ram.2024.02.006. Online ahead of print.ABSTRACTFree-living amoebae (FLA) of the genus Acanthamoeba are ubiquitous and amphizoic protozoa that colonize aquatic and terrestrial habitats and can serve as reservoirs for other microorganisms. They are considered econoses that can cause severe and rare pathologies. Due to limited epidemiological data available, the objective of this study was to investigate the presence of Acanthamoeba in coastal wetlands of the southeast of Buenos Aires province and evaluate their association with bacteriological and enviro...
Source: Revista Argentina de Microbiologia - April 17, 2024 Category: Microbiology Authors: Loriana Tomassini Mar ía Soledad Dominguez Karina Soledad Esquius Viviana Rosa Randazzo Source Type: research

Improving polymerase chain reaction diagnostic rates for herpes simplex keratitis: results of a pilot study
CONCLUSION: Our results suggest that, with proper swabbing technique, PCR may be more sensitive than previously reported.PMID:38601900 | PMC:PMC11001569 | DOI:10.5693/djo.01.2024.01.002 (Source: Herpes)
Source: Herpes - April 11, 2024 Category: Infectious Diseases Authors: Alice L Milligan Jeremy J Hoffman Yan Ning Neo Su-Yin Koay Source Type: research

Enhanced transport of bacteria along root systems by protists can impact plant health
This study elucidates their role in the rhizosphere community and suggests a mechanism by which protists can be used to move bacteria along plant roots. We found that the co-inoculation of protists with nitrogen-fixing beneficial bacteria, Sinorhizobium meliloti, resulted in nodules farther down the roots when compared to plants inoculated with S. meliloti alone, and shoot weights similar to plants that received nitrogen fertilizer. These data illustrate the ability of protists to transport viable bacteria to uninhabited regions of the root system.PMID:38534145 | DOI:10.1128/aem.02011-23 (Source: Applied and Environmental Microbiology)
Source: Applied and Environmental Microbiology - March 27, 2024 Category: Microbiology Authors: Jamie L Micciulla Leslie M Shor Daniel J Gage Source Type: research

Acanthamoeba Infection and Nasal Rinsing, United States, 1994-2022
We describe 10 patients with nonkeratitis Acanthamoeba infection who reported performing nasal rinsing before becoming ill. All were immunocompromised, 7 had chronic sinusitis, and many used tap water for nasal rinsing. Immunocompromised persons should be educated about safe nasal rinsing to prevent free-living ameba infections.PMID:38526242 | DOI:10.3201/eid3004.231076 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Julia C Haston Chelsea Serra Erin Imada Emalee Martin Ibne Karim M Ali Jennifer R Cope Source Type: research

Acanthamoeba Infection and Nasal Rinsing, United States, 1994-2022
We describe 10 patients with nonkeratitis Acanthamoeba infection who reported performing nasal rinsing before becoming ill. All were immunocompromised, 7 had chronic sinusitis, and many used tap water for nasal rinsing. Immunocompromised persons should be educated about safe nasal rinsing to prevent free-living ameba infections.PMID:38526242 | PMC:PMC10977821 | DOI:10.3201/eid3004.231076 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Julia C Haston Chelsea Serra Erin Imada Emalee Martin Ibne Karim M Ali Jennifer R Cope Source Type: research