Cerebrospinal fluid inflammatory cytokine profiles of patients with neurotropic parasitic infections
In this study, cerebral spinal fluid (CSF) samples from suspected patients with parasitic infections were screened for pathogenic free-living amoebae by culture (n=2506) and PCR (n=275). Six proinflammatory cytokines in smear and culture-negative CSF samples from patients with GAE (n = 2), NCC (n = 7), and CT (n = 23) as well as control (n = 7) patients were measured using the Multiplex Suspension assay. None of the CSF samples tested was positive for neurotropic free-living amoebae by culture and only two samples showed Acanthamoeba 18S rRNA by PCR. Of the six cytokines measured, only IL-6 and IL-8 were significantly incr...
Source: Tropical Biomedicine - February 3, 2024 Category: Tropical Medicine Authors: D V John N Sreenivas H Deora M Purushottam M Debnath A Mahadevan S A Patil Source Type: research

Cerebrospinal fluid inflammatory cytokine profiles of patients with neurotropic parasitic infections
In this study, cerebral spinal fluid (CSF) samples from suspected patients with parasitic infections were screened for pathogenic free-living amoebae by culture (n=2506) and PCR (n=275). Six proinflammatory cytokines in smear and culture-negative CSF samples from patients with GAE (n = 2), NCC (n = 7), and CT (n = 23) as well as control (n = 7) patients were measured using the Multiplex Suspension assay. None of the CSF samples tested was positive for neurotropic free-living amoebae by culture and only two samples showed Acanthamoeba 18S rRNA by PCR. Of the six cytokines measured, only IL-6 and IL-8 were significantly incr...
Source: Tropical Biomedicine - February 3, 2024 Category: Tropical Medicine Authors: D V John N Sreenivas H Deora M Purushottam M Debnath A Mahadevan S A Patil Source Type: research

Cerebrospinal fluid inflammatory cytokine profiles of patients with neurotropic parasitic infections
In this study, cerebral spinal fluid (CSF) samples from suspected patients with parasitic infections were screened for pathogenic free-living amoebae by culture (n=2506) and PCR (n=275). Six proinflammatory cytokines in smear and culture-negative CSF samples from patients with GAE (n = 2), NCC (n = 7), and CT (n = 23) as well as control (n = 7) patients were measured using the Multiplex Suspension assay. None of the CSF samples tested was positive for neurotropic free-living amoebae by culture and only two samples showed Acanthamoeba 18S rRNA by PCR. Of the six cytokines measured, only IL-6 and IL-8 were significantly incr...
Source: Tropical Biomedicine - February 3, 2024 Category: Tropical Medicine Authors: D V John N Sreenivas H Deora M Purushottam M Debnath A Mahadevan S A Patil Source Type: research

Cerebrospinal fluid inflammatory cytokine profiles of patients with neurotropic parasitic infections
In this study, cerebral spinal fluid (CSF) samples from suspected patients with parasitic infections were screened for pathogenic free-living amoebae by culture (n=2506) and PCR (n=275). Six proinflammatory cytokines in smear and culture-negative CSF samples from patients with GAE (n = 2), NCC (n = 7), and CT (n = 23) as well as control (n = 7) patients were measured using the Multiplex Suspension assay. None of the CSF samples tested was positive for neurotropic free-living amoebae by culture and only two samples showed Acanthamoeba 18S rRNA by PCR. Of the six cytokines measured, only IL-6 and IL-8 were significantly incr...
Source: Tropical Biomedicine - February 3, 2024 Category: Tropical Medicine Authors: D V John N Sreenivas H Deora M Purushottam M Debnath A Mahadevan S A Patil Source Type: research

Cerebrospinal fluid inflammatory cytokine profiles of patients with neurotropic parasitic infections
In this study, cerebral spinal fluid (CSF) samples from suspected patients with parasitic infections were screened for pathogenic free-living amoebae by culture (n=2506) and PCR (n=275). Six proinflammatory cytokines in smear and culture-negative CSF samples from patients with GAE (n = 2), NCC (n = 7), and CT (n = 23) as well as control (n = 7) patients were measured using the Multiplex Suspension assay. None of the CSF samples tested was positive for neurotropic free-living amoebae by culture and only two samples showed Acanthamoeba 18S rRNA by PCR. Of the six cytokines measured, only IL-6 and IL-8 were significantly incr...
Source: Tropical Biomedicine - February 3, 2024 Category: Tropical Medicine Authors: D V John N Sreenivas H Deora M Purushottam M Debnath A Mahadevan S A Patil Source Type: research

Cerebrospinal fluid inflammatory cytokine profiles of patients with neurotropic parasitic infections
In this study, cerebral spinal fluid (CSF) samples from suspected patients with parasitic infections were screened for pathogenic free-living amoebae by culture (n=2506) and PCR (n=275). Six proinflammatory cytokines in smear and culture-negative CSF samples from patients with GAE (n = 2), NCC (n = 7), and CT (n = 23) as well as control (n = 7) patients were measured using the Multiplex Suspension assay. None of the CSF samples tested was positive for neurotropic free-living amoebae by culture and only two samples showed Acanthamoeba 18S rRNA by PCR. Of the six cytokines measured, only IL-6 and IL-8 were significantly incr...
Source: Tropical Biomedicine - February 3, 2024 Category: Tropical Medicine Authors: D V John N Sreenivas H Deora M Purushottam M Debnath A Mahadevan S A Patil Source Type: research

Cerebrospinal fluid inflammatory cytokine profiles of patients with neurotropic parasitic infections
In this study, cerebral spinal fluid (CSF) samples from suspected patients with parasitic infections were screened for pathogenic free-living amoebae by culture (n=2506) and PCR (n=275). Six proinflammatory cytokines in smear and culture-negative CSF samples from patients with GAE (n = 2), NCC (n = 7), and CT (n = 23) as well as control (n = 7) patients were measured using the Multiplex Suspension assay. None of the CSF samples tested was positive for neurotropic free-living amoebae by culture and only two samples showed Acanthamoeba 18S rRNA by PCR. Of the six cytokines measured, only IL-6 and IL-8 were significantly incr...
Source: Tropical Biomedicine - February 3, 2024 Category: Tropical Medicine Authors: D V John N Sreenivas H Deora M Purushottam M Debnath A Mahadevan S A Patil Source Type: research

Cerebrospinal fluid inflammatory cytokine profiles of patients with neurotropic parasitic infections
In this study, cerebral spinal fluid (CSF) samples from suspected patients with parasitic infections were screened for pathogenic free-living amoebae by culture (n=2506) and PCR (n=275). Six proinflammatory cytokines in smear and culture-negative CSF samples from patients with GAE (n = 2), NCC (n = 7), and CT (n = 23) as well as control (n = 7) patients were measured using the Multiplex Suspension assay. None of the CSF samples tested was positive for neurotropic free-living amoebae by culture and only two samples showed Acanthamoeba 18S rRNA by PCR. Of the six cytokines measured, only IL-6 and IL-8 were significantly incr...
Source: Tropical Biomedicine - February 3, 2024 Category: Tropical Medicine Authors: D V John N Sreenivas H Deora M Purushottam M Debnath A Mahadevan S A Patil Source Type: research

Cerebrospinal fluid inflammatory cytokine profiles of patients with neurotropic parasitic infections
In this study, cerebral spinal fluid (CSF) samples from suspected patients with parasitic infections were screened for pathogenic free-living amoebae by culture (n=2506) and PCR (n=275). Six proinflammatory cytokines in smear and culture-negative CSF samples from patients with GAE (n = 2), NCC (n = 7), and CT (n = 23) as well as control (n = 7) patients were measured using the Multiplex Suspension assay. None of the CSF samples tested was positive for neurotropic free-living amoebae by culture and only two samples showed Acanthamoeba 18S rRNA by PCR. Of the six cytokines measured, only IL-6 and IL-8 were significantly incr...
Source: Tropical Biomedicine - February 3, 2024 Category: Tropical Medicine Authors: D V John N Sreenivas H Deora M Purushottam M Debnath A Mahadevan S A Patil Source Type: research

Investigation of the Inhibition Effect of Acanthamoeba Cell-Free Supernatants Against Pseudomonas aeruginosa
Mikrobiyol Bul. 2024 Jan;58(1):71-79. doi: 10.5578/mb.20249950.ABSTRACTFree-living amoebae belonging to the genus Acanthamoeba are microorganisms that live in air, soil and aquatic environments. In humans, they cause infections such as amoebic keratitis, graulamotous amoebic encephalitis that are difficult to treat and can be fatal. In addition, it is known that they contribute to the replication of bacteria and increase their pathogenicity by being a host for various bacteria. However, information on its inhibitory properties against bacteria and its production of antimicrobial agents is very limited. In this context, in ...
Source: Mikrobiyoloji Bulteni - January 24, 2024 Category: Microbiology Authors: Çise Kebabcı Zuhal Zeybek Source Type: research