Free Living Amoebozoa Infection Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Comparison of therapeutic effects between big-bubble deep anterior lamellar keratoplasty and penetrating keratoplasty for medically unresponsive Acanthamoeba keratitis
To compare the outcomes of big-bubble deep anterior lamellar keratoplasty (BB-DALK) and penetrating keratoplasty (PKP) in the management of medically unresponsive Acanthamoeba keratitis (AK). (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - March 4, 2024 Category: Infectious Diseases Authors: Xiaolin Qi, Huilin Mao, Jinhui Liu, Yanling Dong, Man Du, Ting Liu, Ting Zhang, Xiuhai Lu and Hua Gao Tags: Research Source Type: research

Self-assembled micelles loaded with itraconazole as anti-Acanthamoeba nano-formulation
Arch Microbiol. 2024 Mar 4;206(4):134. doi: 10.1007/s00203-024-03854-3.ABSTRACTAcanthamoeba castellanii are opportunistic pathogens known to cause infection of the central nervous system termed: granulomatous amoebic encephalitis, that mostly effects immunocompromised individuals, and a sight threatening keratitis, known as Acanthamoeba keratitis, which mostly affects contact lens wearers. The current treatment available is problematic, and is toxic. Herein, an amphiphilic star polymer with AB2 miktoarms [A = hydrophobic poly(ℇ-Caprolacton) and B = hydrophilic poly (ethylene glycol)] was synthesized by ring opening polym...
Source: Archives of Microbiology - March 3, 2024 Category: Microbiology Authors: Komal Rao Muhammad Abdullah Usman Ahmed Hashi Isse Wehelie Muhammad Raza Shah Ruqaiyyah Siddiqui Naveed A Khan Bader S Alawfi Ayaz Anwar Source Type: research

Prevention in the Management of Infectious Keratitis
The morbidity associated with infectious keratitis (IK) has been increasingly recognized globally, especially among developing countries. International corneal specialists have recommended that this condition should be classified as a neglected tropical disease so that it gets the policy attention it deserves. Bacteria, fungi, and acanthamoeba are the common etiological agents, and the incidence and proportion varies with different geographic locations. Unlike other visually debilitating conditions such as glaucoma and diabetic retinopathy, both of which may cause blindness without the patient being aware, IK causes signif...
Source: JAMA Ophthalmology - March 1, 2024 Category: Opthalmology Source Type: research

Identification of Candida albicans and non-MRSA Staphylococcus aureus in free-living amoebae isolated from the hospital wards; an alarm for distribution of nosocomial infections via FLA
. (Source: International Journal of Environmental Health Research)
Source: International Journal of Environmental Health Research - February 28, 2024 Category: Environmental Health Authors: Fatemeh MahdaviMarziye FatemiHanieh Mohammad RahimiMaryam NiyyatiAbbas YadegarHamed Mirjalalia Department of Medical Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iranb Foodborne and Waterborne Dise Source Type: research

Amoebicidal effect of synthetic indoles against < em > Acanthamoeba < /em > spp.: a study of cell death
Antimicrob Agents Chemother. 2024 Feb 27:e0165123. doi: 10.1128/aac.01651-23. Online ahead of print.ABSTRACTOrganic and synthetic chemistry plays a crucial role in drug discovery fields. Moreover, chemical modifications of available molecules to enhance their efficacy, selectivity and safety have been considered as an attractive approach for the development of new bioactive agents. Indoles, a versatile group of natural heterocyclic compounds, have been widely used in pharmaceutical industry due to their broad spectrum of activities including antimicrobial, antitumoral and anti-inflammatory among others. Herein, we report t...
Source: Antimicrobial Agents and Chemotherapy - February 27, 2024 Category: Microbiology Authors: Ines Sifaoui Rub én L Rodríguez-Expósito Mar ía Reyes-Batlle Alejandra Dumpi érrez Ramos Raquel Diana-Rivero Fernando Garc ía-Tellado David Tejedor Jos é E Piñero Jacob Lorenzo-Morales Source Type: research

Metagenomic next-generation sequencing for diagnosis of fatal Balamuthia amoebic encephalitis
CONCLUSION: This study highlights the application of mNGS for the diagnosis of patients with suspected encephalitis or meningitis, especially those caused by rare opportunistic infections.PMID:38382768 | DOI:10.1016/j.meegid.2024.105570 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - February 21, 2024 Category: Genetics & Stem Cells Authors: Lixia Qin Yaqin Xiang Ziwei Wu Hainan Zhang Xiaomei Wu Qihua Chen Source Type: research

Evolution of microRNAs in Amoebozoa and implications for the origin of multicellularity
Nucleic Acids Res. 2024 Feb 20:gkae109. doi: 10.1093/nar/gkae109. Online ahead of print.ABSTRACTMicroRNAs (miRNAs) are important and ubiquitous regulators of gene expression in both plants and animals. They are thought to have evolved convergently in these lineages and hypothesized to have played a role in the evolution of multicellularity. In line with this hypothesis, miRNAs have so far only been described in few unicellular eukaryotes. Here, we investigate the presence and evolution of miRNAs in Amoebozoa, focusing on species belonging to Acanthamoeba, Physarum and dictyostelid taxonomic groups, representing a range of ...
Source: Cell Research - February 20, 2024 Category: Cytology Authors: Bart Edelbroek Jonas Kjellin Inna Biryukova Zhen Liao Torgny Lundberg Angelika A Noegel Ludwig Eichinger Marc R Friedl änder Fredrik S öderbom Source Type: research

Influence of salt and temperature in the growth of pathogenic freeliving amoebae
Free-living amoebae are an extensive group of protistans that can be found in a wide variety of environments. Among them, the Acanthamoeba genus and Naegleria fowleri stand out as two of the most pathogenic amoebae and with a higher number of reported cases. N. fowleri is mainly found in warm freshwater water bodies whereas amoebae of the Acanthamoeba genus are broadly distributed through natural and anthropogenic environments. In this regard, the management and the control of the amoebic populations in swimming pools has become a major public health challenge for institutions. The aim of this work was to evaluate the grow...
Source: Frontiers in Microbiology - February 15, 2024 Category: Microbiology Source Type: research

Influence of salt and temperature in the growth of pathogenic free-living amoebae
IntroductionFree-living amoebae are an extensive group of protistans that can be found in a wide variety of environments. Among them, the Acanthamoeba genus and Naegleria fowleri stand out as two of the most pathogenic amoebae and with a higher number of reported cases. N. fowleri is mainly found in warm freshwater water bodies whereas amoebae of the Acanthamoeba genus are broadly distributed through natural and anthropogenic environments. In this regard, the management and the control of the amoebic populations in swimming pools has become a major public health challenge for institutions.MethodsThe aim of this work was to...
Source: Frontiers in Microbiology - February 15, 2024 Category: Microbiology Source Type: research

Environmental Detection of Parasites in the Marginalized Paiute Reservations Compared to a Nearby Area
Am J Trop Med Hyg. 2024 Feb 13:tpmd230712. doi: 10.4269/ajtmh.23-0712. Online ahead of print.ABSTRACTThe amounts of parasite DNA in soil samples from different playgrounds and other public areas can help identify areas of possible microbe transmission and give indications of the possible occurrence of parasite infection in nearby communities. We collected 207 soil samples from parks in Paiute indigenous tribal areas in southwestern Utah and from the higher income city of St. George, Utah, and tested them for 11 parasites that can cause human disease. Molecular tests revealed an elevated odds ratio (OR) of 3.072 (range, 1.1...
Source: Am J Trop Med Hyg - February 13, 2024 Category: Infectious Diseases Authors: Shannon McKim Kristen Kopystynsky Nathaniel Wolf Fahim A Akbar Maria Elena Bottazzi Peter J Hotez Rojelio Mejia Source Type: research

Environmental Detection of Parasites in the Marginalized Paiute Reservations Compared to a Nearby Area
Am J Trop Med Hyg. 2024 Feb 13:tpmd230712. doi: 10.4269/ajtmh.23-0712. Online ahead of print.ABSTRACTThe amounts of parasite DNA in soil samples from different playgrounds and other public areas can help identify areas of possible microbe transmission and give indications of the possible occurrence of parasite infection in nearby communities. We collected 207 soil samples from parks in Paiute indigenous tribal areas in southwestern Utah and from the higher income city of St. George, Utah, and tested them for 11 parasites that can cause human disease. Molecular tests revealed an elevated odds ratio (OR) of 3.072 (range, 1.1...
Source: The American Journal of Tropical Medicine and Hygiene - February 13, 2024 Category: Tropical Medicine Authors: Shannon McKim Kristen Kopystynsky Nathaniel Wolf Fahim A Akbar Maria Elena Bottazzi Peter J Hotez Rojelio Mejia Source Type: research