AI in the repurposing of potential herbs for filariasis therapy
CONCLUSION: ChatGPT shows promise as a useful method for repurposing drugs in the treatment of filariasis. Its thorough and brief responses make it useful for finding possible pharmacological candidates. However, it is critical to recognize ChatGPT's limitations, such as the requirement for additional clinical information and the inability to change therapy. Further research and development are required to optimize its use in filariasis therapy settings.PMID:38238871 | DOI:10.4103/0972-9062.393975 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - January 18, 2024 Category: Infectious Diseases Authors: Somsri Wiwanitmkit Viroj Wiwanitkit Source Type: research

The lymphatic filariasis treatment study landscape: A systematic review of study characteristics and the case for an individual participant data platform
ConclusionsThe LF treatment study landscape is heterogeneous, but the abundance of studies and related IPD suggest that establishing a global data repository to facilitate IPD meta-analyses would be feasible and useful to address unresolved questions on variation in treatment outcomes across geographies, demographics and in underrepresented groups. New studies using more standardized approaches should be initiated to address the scarcity and inconsistency of data on morbidity management. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - January 16, 2024 Category: Tropical Medicine Authors: Luzia T. Freitas Source Type: research

Self-care practices and quality of life of filariasis patients in a gram panchayat of Paschim Burdwan district, West Bengal, India
CONCLUSION: Self-care practice is not known to the affected patients. Time has also come to integrate measures like rehabilitation, psychological intervention, social assistance in addition to self-care management to put up a holistic approach of the existing program.PMID:38174516 | DOI:10.4103/0972-9062.374239 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - January 4, 2024 Category: Infectious Diseases Authors: Indranil Saha Russoti Das Ajay Kumar Mandal Pinki Darlami Subhajit Datta Gautam Ghose Sanjit Dey Source Type: research

Camel filariasis (Dipetalonema evansi) and its association with clinical balanoposthitis with reference to prominent changes in clinical findings, serum testosterone, semen analysis, and testicular histopathology
The objective of the present work focuse... (Source: BMC Veterinary Research)
Source: BMC Veterinary Research - January 3, 2024 Category: Veterinary Research Authors: Arafat Khalphallah, Taher Al-Daek, Mahmoud Abdelhamid, Enas Elmeligy, Sayed Fathi El-Hawari, Khaled A. Khesruf, Heba A. Nasr and Ragab H. Mohamed Tags: Research Source Type: research

The current status of neglected tropical diseases in Japan: A scoping review
by Yuriko Harada, Hanako Iwashita, Taeko Moriyasu, Sachiyo Nagi, Nobuo Saito, Mariko Sugawara-Mikami, Kota Yoshioka, Rie Yotsu, on behalf of Japan NTD Study Group Little attention has been paid to neglected tropical diseases (NTDs) in high-income countries and no literature provides an overview of NTDs in Japan. This scoping review aims to synthesize the latest evidence and information to understand epidemiology of and public health response to NTDs in Japan. Using three academic databases, we retrieved articles that mentioned NTDs in Japan, written in English or Japanese, and published between 2010 and 2020. Websites of ...
Source: PLoS Neglected Tropical Diseases - January 2, 2024 Category: Tropical Medicine Authors: Yuriko Harada Source Type: research

Five years of post-validation surveillance of lymphatic filariasis in Thailand
ConclusionsIn 2022, after 5  years of PVS, Thailand re-surveyed 41% of its previously endemic IUs and demonstrated ongoing transmission in only one province of Narathiwat, where Mf prevalence is below the WHO provisional transmission threshold of 1%. This study highlights the importance of continued disease surveillance measu res and vigilance among health care providers in LF receptive areas.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - December 6, 2023 Category: Infectious Diseases Source Type: research

Synthesis of findings from the literature and a qualitative research study on the impacts of gender, disability, and ethnicity in Neglected Tropical Diseases programs
DiscussionPrograms to address NTDs can promote equity and improve programming by increasing women ’s participation as CDDs and providing financial compensation. Additionally, programs should prioritize inclusive training for CDDs, and inclusive messaging about MDA for communities. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - December 4, 2023 Category: Tropical Medicine Authors: Jennifer K. Arney Source Type: research

Surveillance and Selective Treatment of Brugia malayi Filariasis Eleven Years after Stopping Mass Drug Administration in Belitung District, Indonesia
Am J Trop Med Hyg. 2023 Nov 27:tpmd230255. doi: 10.4269/ajtmh.23-0255. Online ahead of print.ABSTRACTBrugia malayi is the major cause of lymphatic filariasis (LF) in Indonesia. Zoophilic B. malayi was endemic in Belitung district, and mass drug administration (MDA) with diethylcarbamazine (DEC) and albendazole ceased after five annual rounds in 2010. The district passed three transmission assessment surveys (TAS) between 2011 and 2016. As part of the post-TAS3 surveillance of the national LF elimination program, we collected night blood samples for microfilaria (Mf) detection from 1,911 subjects more than 5 years of age in...
Source: The American Journal of Tropical Medicine and Hygiene - November 27, 2023 Category: Tropical Medicine Authors: Taniawati Supali Yenny Djuardi None Santoso Lita Renata Sianipar Nungki Hapsari Suryaningtyas Rahmat Alfian Yossi Destani Elisa Iskandar Hendri Astuty Noviani Sugianto Peter U Fischer Source Type: research

Surveillance and Selective Treatment of Brugia malayi Filariasis Eleven Years after Stopping Mass Drug Administration in Belitung District, Indonesia
Am J Trop Med Hyg. 2023 Nov 27:tpmd230255. doi: 10.4269/ajtmh.23-0255. Online ahead of print.ABSTRACTBrugia malayi is the major cause of lymphatic filariasis (LF) in Indonesia. Zoophilic B. malayi was endemic in Belitung district, and mass drug administration (MDA) with diethylcarbamazine (DEC) and albendazole ceased after five annual rounds in 2010. The district passed three transmission assessment surveys (TAS) between 2011 and 2016. As part of the post-TAS3 surveillance of the national LF elimination program, we collected night blood samples for microfilaria (Mf) detection from 1,911 subjects more than 5 years of age in...
Source: Am J Trop Med Hyg - November 27, 2023 Category: Infectious Diseases Authors: Taniawati Supali Yenny Djuardi None Santoso Lita Renata Sianipar Nungki Hapsari Suryaningtyas Rahmat Alfian Yossi Destani Elisa Iskandar Hendri Astuty Noviani Sugianto Peter U Fischer Source Type: research

Surveillance and Selective Treatment of Brugia malayi Filariasis Eleven Years after Stopping Mass Drug Administration in Belitung District, Indonesia
Am J Trop Med Hyg. 2023 Nov 27:tpmd230255. doi: 10.4269/ajtmh.23-0255. Online ahead of print.ABSTRACTBrugia malayi is the major cause of lymphatic filariasis (LF) in Indonesia. Zoophilic B. malayi was endemic in Belitung district, and mass drug administration (MDA) with diethylcarbamazine (DEC) and albendazole ceased after five annual rounds in 2010. The district passed three transmission assessment surveys (TAS) between 2011 and 2016. As part of the post-TAS3 surveillance of the national LF elimination program, we collected night blood samples for microfilaria (Mf) detection from 1,911 subjects more than 5 years of age in...
Source: The American Journal of Tropical Medicine and Hygiene - November 27, 2023 Category: Tropical Medicine Authors: Taniawati Supali Yenny Djuardi None Santoso Lita Renata Sianipar Nungki Hapsari Suryaningtyas Rahmat Alfian Yossi Destani Elisa Iskandar Hendri Astuty Noviani Sugianto Peter U Fischer Source Type: research

Surveillance and Selective Treatment of Brugia malayi Filariasis Eleven Years after Stopping Mass Drug Administration in Belitung District, Indonesia
Am J Trop Med Hyg. 2023 Nov 27:tpmd230255. doi: 10.4269/ajtmh.23-0255. Online ahead of print.ABSTRACTBrugia malayi is the major cause of lymphatic filariasis (LF) in Indonesia. Zoophilic B. malayi was endemic in Belitung district, and mass drug administration (MDA) with diethylcarbamazine (DEC) and albendazole ceased after five annual rounds in 2010. The district passed three transmission assessment surveys (TAS) between 2011 and 2016. As part of the post-TAS3 surveillance of the national LF elimination program, we collected night blood samples for microfilaria (Mf) detection from 1,911 subjects more than 5 years of age in...
Source: Am J Trop Med Hyg - November 27, 2023 Category: Infectious Diseases Authors: Taniawati Supali Yenny Djuardi None Santoso Lita Renata Sianipar Nungki Hapsari Suryaningtyas Rahmat Alfian Yossi Destani Elisa Iskandar Hendri Astuty Noviani Sugianto Peter U Fischer Source Type: research