A Health Survey Revealing Prevalence of Vector-Borne Diseases and Tuberculosis in Papua New Guinea Defence Force Personnel and Families
Am J Trop Med Hyg. 2023 Sep 25:tpmd230341. doi: 10.4269/ajtmh.23-0341. Online ahead of print.ABSTRACTThe Papua New Guinean Defence Force (PNGDF) and the Australian Defence Force (ADF) work and train closely. Infectious diseases pose a health threat to both forces, but recent knowledge about the risk at military bases in Papua New Guinea is limited. To improve understanding, a collaborative cross-sectional survey was conducted (March-April 2019) at Lombrum Naval base (Manus province) and Moem Army barracks (Wewak, East Sepik province) plus its Vanimo outpost (Sandaun province). Clinical data, venous blood, and sputum were c...
Source: Am J Trop Med Hyg - September 25, 2023 Category: Infectious Diseases Authors: Fiona McCallum Krond Mond Qin Cheng Luis Furuya-Kanamori Alyson Auliff Peter Kaminiel ADFMIDI/PNGDF Health Services Survey Team Source Type: research

A Health Survey Revealing Prevalence of Vector-Borne Diseases and Tuberculosis in Papua New Guinea Defence Force Personnel and Families
Am J Trop Med Hyg. 2023 Sep 25:tpmd230341. doi: 10.4269/ajtmh.23-0341. Online ahead of print.ABSTRACTThe Papua New Guinean Defence Force (PNGDF) and the Australian Defence Force (ADF) work and train closely. Infectious diseases pose a health threat to both forces, but recent knowledge about the risk at military bases in Papua New Guinea is limited. To improve understanding, a collaborative cross-sectional survey was conducted (March-April 2019) at Lombrum Naval base (Manus province) and Moem Army barracks (Wewak, East Sepik province) plus its Vanimo outpost (Sandaun province). Clinical data, venous blood, and sputum were c...
Source: The American Journal of Tropical Medicine and Hygiene - September 25, 2023 Category: Tropical Medicine Authors: Fiona McCallum Krond Mond Qin Cheng Luis Furuya-Kanamori Alyson Auliff Peter Kaminiel ADFMIDI/PNGDF Health Services Survey Team Source Type: research

A Health Survey Revealing Prevalence of Vector-Borne Diseases and Tuberculosis in Papua New Guinea Defence Force Personnel and Families
Am J Trop Med Hyg. 2023 Sep 25:tpmd230341. doi: 10.4269/ajtmh.23-0341. Online ahead of print.ABSTRACTThe Papua New Guinean Defence Force (PNGDF) and the Australian Defence Force (ADF) work and train closely. Infectious diseases pose a health threat to both forces, but recent knowledge about the risk at military bases in Papua New Guinea is limited. To improve understanding, a collaborative cross-sectional survey was conducted (March-April 2019) at Lombrum Naval base (Manus province) and Moem Army barracks (Wewak, East Sepik province) plus its Vanimo outpost (Sandaun province). Clinical data, venous blood, and sputum were c...
Source: Am J Trop Med Hyg - September 25, 2023 Category: Infectious Diseases Authors: Fiona McCallum Krond Mond Qin Cheng Luis Furuya-Kanamori Alyson Auliff Peter Kaminiel ADFMIDI/PNGDF Health Services Survey Team Source Type: research

A Health Survey Revealing Prevalence of Vector-Borne Diseases and Tuberculosis in Papua New Guinea Defence Force Personnel and Families
Am J Trop Med Hyg. 2023 Sep 25:tpmd230341. doi: 10.4269/ajtmh.23-0341. Online ahead of print.ABSTRACTThe Papua New Guinean Defence Force (PNGDF) and the Australian Defence Force (ADF) work and train closely. Infectious diseases pose a health threat to both forces, but recent knowledge about the risk at military bases in Papua New Guinea is limited. To improve understanding, a collaborative cross-sectional survey was conducted (March-April 2019) at Lombrum Naval base (Manus province) and Moem Army barracks (Wewak, East Sepik province) plus its Vanimo outpost (Sandaun province). Clinical data, venous blood, and sputum were c...
Source: The American Journal of Tropical Medicine and Hygiene - September 25, 2023 Category: Tropical Medicine Authors: Fiona McCallum Krond Mond Qin Cheng Luis Furuya-Kanamori Alyson Auliff Peter Kaminiel ADFMIDI/PNGDF Health Services Survey Team Source Type: research

A Health Survey Revealing Prevalence of Vector-Borne Diseases and Tuberculosis in Papua New Guinea Defence Force Personnel and Families
Am J Trop Med Hyg. 2023 Sep 25:tpmd230341. doi: 10.4269/ajtmh.23-0341. Online ahead of print.ABSTRACTThe Papua New Guinean Defence Force (PNGDF) and the Australian Defence Force (ADF) work and train closely. Infectious diseases pose a health threat to both forces, but recent knowledge about the risk at military bases in Papua New Guinea is limited. To improve understanding, a collaborative cross-sectional survey was conducted (March-April 2019) at Lombrum Naval base (Manus province) and Moem Army barracks (Wewak, East Sepik province) plus its Vanimo outpost (Sandaun province). Clinical data, venous blood, and sputum were c...
Source: Am J Trop Med Hyg - September 25, 2023 Category: Infectious Diseases Authors: Fiona McCallum Krond Mond Qin Cheng Luis Furuya-Kanamori Alyson Auliff Peter Kaminiel ADFMIDI/PNGDF Health Services Survey Team Source Type: research

A Health Survey Revealing Prevalence of Vector-Borne Diseases and Tuberculosis in Papua New Guinea Defence Force Personnel and Families
Am J Trop Med Hyg. 2023 Sep 25:tpmd230341. doi: 10.4269/ajtmh.23-0341. Online ahead of print.ABSTRACTThe Papua New Guinean Defence Force (PNGDF) and the Australian Defence Force (ADF) work and train closely. Infectious diseases pose a health threat to both forces, but recent knowledge about the risk at military bases in Papua New Guinea is limited. To improve understanding, a collaborative cross-sectional survey was conducted (March-April 2019) at Lombrum Naval base (Manus province) and Moem Army barracks (Wewak, East Sepik province) plus its Vanimo outpost (Sandaun province). Clinical data, venous blood, and sputum were c...
Source: The American Journal of Tropical Medicine and Hygiene - September 25, 2023 Category: Tropical Medicine Authors: Fiona McCallum Krond Mond Qin Cheng Luis Furuya-Kanamori Alyson Auliff Peter Kaminiel ADFMIDI/PNGDF Health Services Survey Team Source Type: research

A Health Survey Revealing Prevalence of Vector-Borne Diseases and Tuberculosis in Papua New Guinea Defence Force Personnel and Families
Am J Trop Med Hyg. 2023 Sep 25:tpmd230341. doi: 10.4269/ajtmh.23-0341. Online ahead of print.ABSTRACTThe Papua New Guinean Defence Force (PNGDF) and the Australian Defence Force (ADF) work and train closely. Infectious diseases pose a health threat to both forces, but recent knowledge about the risk at military bases in Papua New Guinea is limited. To improve understanding, a collaborative cross-sectional survey was conducted (March-April 2019) at Lombrum Naval base (Manus province) and Moem Army barracks (Wewak, East Sepik province) plus its Vanimo outpost (Sandaun province). Clinical data, venous blood, and sputum were c...
Source: Am J Trop Med Hyg - September 25, 2023 Category: Infectious Diseases Authors: Fiona McCallum Krond Mond Qin Cheng Luis Furuya-Kanamori Alyson Auliff Peter Kaminiel ADFMIDI/PNGDF Health Services Survey Team Source Type: research

A Health Survey Revealing Prevalence of Vector-Borne Diseases and Tuberculosis in Papua New Guinea Defence Force Personnel and Families
Am J Trop Med Hyg. 2023 Sep 25:tpmd230341. doi: 10.4269/ajtmh.23-0341. Online ahead of print.ABSTRACTThe Papua New Guinean Defence Force (PNGDF) and the Australian Defence Force (ADF) work and train closely. Infectious diseases pose a health threat to both forces, but recent knowledge about the risk at military bases in Papua New Guinea is limited. To improve understanding, a collaborative cross-sectional survey was conducted (March-April 2019) at Lombrum Naval base (Manus province) and Moem Army barracks (Wewak, East Sepik province) plus its Vanimo outpost (Sandaun province). Clinical data, venous blood, and sputum were c...
Source: The American Journal of Tropical Medicine and Hygiene - September 25, 2023 Category: Tropical Medicine Authors: Fiona McCallum Krond Mond Qin Cheng Luis Furuya-Kanamori Alyson Auliff Peter Kaminiel ADFMIDI/PNGDF Health Services Survey Team Source Type: research

Diethylcarbamazine elicits Ca < sup > 2+ < /sup > signals through TRP-2 channels that are potentiated by emodepside in < em > Brugia malayi < /em > muscles
Antimicrob Agents Chemother. 2023 Sep 20:e0041923. doi: 10.1128/aac.00419-23. Online ahead of print.ABSTRACTFilarial nematode infections are a major health concern in several countries. Lymphatic filariasis is caused by Wuchereria bancrofti and Brugia spp. affecting over 120 million people. Heavy infections can lead to elephantiasis, which has serious effects on individuals' lives. Although current anthelmintics are effective at killing microfilariae in the bloodstream, they have little to no effect against adult parasites found in the lymphatic system. The anthelmintic diethylcarbamazine is one of the central pillars of l...
Source: Antimicrobial Agents and Chemotherapy - September 20, 2023 Category: Microbiology Authors: Paul D E Williams Sudhanva S Kashyap Alan P Robertson Richard J Martin Source Type: research

Diethylcarbamazine elicits Ca < sup > 2+ < /sup > signals through TRP-2 channels that are potentiated by emodepside in < em > Brugia malayi < /em > muscles
Antimicrob Agents Chemother. 2023 Sep 20:e0041923. doi: 10.1128/aac.00419-23. Online ahead of print.ABSTRACTFilarial nematode infections are a major health concern in several countries. Lymphatic filariasis is caused by Wuchereria bancrofti and Brugia spp. affecting over 120 million people. Heavy infections can lead to elephantiasis, which has serious effects on individuals' lives. Although current anthelmintics are effective at killing microfilariae in the bloodstream, they have little to no effect against adult parasites found in the lymphatic system. The anthelmintic diethylcarbamazine is one of the central pillars of l...
Source: Antimicrobial Agents and Chemotherapy - September 20, 2023 Category: Microbiology Authors: Paul D E Williams Sudhanva S Kashyap Alan P Robertson Richard J Martin Source Type: research

Diethylcarbamazine elicits Ca < sup > 2+ < /sup > signals through TRP-2 channels that are potentiated by emodepside in < em > Brugia malayi < /em > muscles
Antimicrob Agents Chemother. 2023 Sep 20:e0041923. doi: 10.1128/aac.00419-23. Online ahead of print.ABSTRACTFilarial nematode infections are a major health concern in several countries. Lymphatic filariasis is caused by Wuchereria bancrofti and Brugia spp. affecting over 120 million people. Heavy infections can lead to elephantiasis, which has serious effects on individuals' lives. Although current anthelmintics are effective at killing microfilariae in the bloodstream, they have little to no effect against adult parasites found in the lymphatic system. The anthelmintic diethylcarbamazine is one of the central pillars of l...
Source: Antimicrobial Agents and Chemotherapy - September 20, 2023 Category: Microbiology Authors: Paul D E Williams Sudhanva S Kashyap Alan P Robertson Richard J Martin Source Type: research

Diethylcarbamazine elicits Ca < sup > 2+ < /sup > signals through TRP-2 channels that are potentiated by emodepside in < em > Brugia malayi < /em > muscles
Antimicrob Agents Chemother. 2023 Sep 20:e0041923. doi: 10.1128/aac.00419-23. Online ahead of print.ABSTRACTFilarial nematode infections are a major health concern in several countries. Lymphatic filariasis is caused by Wuchereria bancrofti and Brugia spp. affecting over 120 million people. Heavy infections can lead to elephantiasis, which has serious effects on individuals' lives. Although current anthelmintics are effective at killing microfilariae in the bloodstream, they have little to no effect against adult parasites found in the lymphatic system. The anthelmintic diethylcarbamazine is one of the central pillars of l...
Source: Antimicrobial Agents and Chemotherapy - September 20, 2023 Category: Microbiology Authors: Paul D E Williams Sudhanva S Kashyap Alan P Robertson Richard J Martin Source Type: research

Diethylcarbamazine elicits Ca < sup > 2+ < /sup > signals through TRP-2 channels that are potentiated by emodepside in < em > Brugia malayi < /em > muscles
Antimicrob Agents Chemother. 2023 Sep 20:e0041923. doi: 10.1128/aac.00419-23. Online ahead of print.ABSTRACTFilarial nematode infections are a major health concern in several countries. Lymphatic filariasis is caused by Wuchereria bancrofti and Brugia spp. affecting over 120 million people. Heavy infections can lead to elephantiasis, which has serious effects on individuals' lives. Although current anthelmintics are effective at killing microfilariae in the bloodstream, they have little to no effect against adult parasites found in the lymphatic system. The anthelmintic diethylcarbamazine is one of the central pillars of l...
Source: Antimicrobial Agents and Chemotherapy - September 20, 2023 Category: Microbiology Authors: Paul D E Williams Sudhanva S Kashyap Alan P Robertson Richard J Martin Source Type: research

Safety and tolerability of moxidectin and ivermectin combination treatments for lymphatic filariasis in C ôte d’Ivoire: A randomized controlled superiority study
ConclusionAll treatment regimens were well tolerated. We observed no difference in safety parameters between regimens that contained ivermectin or moxidectin. Trial registrationClinicaltrials.gov, NCT04410406. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - September 18, 2023 Category: Tropical Medicine Authors: Catherine M. Bjerum Source Type: research

Integrated Prevalence Assessment of Wuchereria bancrofti and Onchocerca volvulus in Three Co-Endemic Districts of Gambella Region, Ethiopia
Am J Trop Med Hyg. 2023 Sep 11:tpmd220392. doi: 10.4269/ajtmh.22-0392. Online ahead of print.ABSTRACTLymphatic filariasis (LF) and onchocerciasis (OV) are among the neglected tropical diseases (NTD) targeted for elimination in Ethiopia. We used a transmission assessment survey (TAS-1) to evaluate the serological status of OV in three co-endemic districts in Gambella simultaneously. During May and June 2019, blood samples were collected from 6- to 7-year-old children who were randomly selected through standard community-based TAS methodology. Children were tested for both circulating filarial antigen (CFA) for LF via filari...
Source: The American Journal of Tropical Medicine and Hygiene - September 11, 2023 Category: Tropical Medicine Authors: Mohammed Hassen Aderajew Mohammed Tekola Endeshaw Tewodros Seid Fikresilasie Samuel Tadese Asmare Henok Birhanu Firdaweke Bekele Adane Yayeh Fikre Seife Mossie Tamiru Kadu Meribo Zerihun Tadesse Emily Griswold Moses Katabarwa Frank Richards Gregory S Nola Source Type: research