Genetic diversity and characterization of Wolbachia endosymbiont in canine filariasis
This study aims to characterize Wolbachia sp. and determine the association between Wolbachia and canine filarial nematode species in Thailand. A total of 46 dog blood samples that were naturally infected with filarial nematodes were obtained to identify filarial nematode species by Giemsa stained under a light microscope and confirmed using the molecular technique. In order to characterize Wolbachia sp., the nested PCR assay targeting the 16S rRNA gene showed that all samples of Dirofilaria immitis and fifteen samples of Candidatus Dirofilaria hongkongensis were grouped into Wolbachia supergroup C. In addition, all sample...
Source: Acta Tropica - August 11, 2023 Category: Infectious Diseases Authors: Patchana Kamkong Wanarit Jitsamai Kritsada Thongmeesee Panan Ratthawongjirakul Piyanan Taweethavonsawat Source Type: research

Genetic diversity and characterization of Wolbachia endosymbiont in canine filariasis
This study aims to characterize Wolbachia sp. and determine the association between Wolbachia and canine filarial nematode species in Thailand. A total of 46 dog blood samples that were naturally infected with filarial nematodes were obtained to identify filarial nematode species by Giemsa stained under a light microscope and confirmed using the molecular technique. In order to characterize Wolbachia sp., the nested PCR assay targeting the 16S rRNA gene showed that all samples of Dirofilaria immitis and fifteen samples of Candidatus Dirofilaria hongkongensis were grouped into Wolbachia supergroup C. In addition, all sample...
Source: Acta Tropica - August 11, 2023 Category: Infectious Diseases Authors: Patchana Kamkong Wanarit Jitsamai Kritsada Thongmeesee Panan Ratthawongjirakul Piyanan Taweethavonsawat Source Type: research

Genetic diversity and characterization of Wolbachia endosymbiont in canine filariasis
This study aims to characterize Wolbachia sp. and determine the association between Wolbachia and canine filarial nematode species in Thailand. A total of 46 dog blood samples that were naturally infected with filarial nematodes were obtained to identify filarial nematode species by Giemsa stained under a light microscope and confirmed using the molecular technique. In order to characterize Wolbachia sp., the nested PCR assay targeting the 16S rRNA gene showed that all samples of Dirofilaria immitis and fifteen samples of Candidatus Dirofilaria hongkongensis were grouped into Wolbachia supergroup C. In addition, all sample...
Source: Acta Tropica - August 11, 2023 Category: Infectious Diseases Authors: Patchana Kamkong Wanarit Jitsamai Kritsada Thongmeesee Panan Ratthawongjirakul Piyanan Taweethavonsawat Source Type: research

Genetic diversity and characterization of Wolbachia endosymbiont in canine filariasis
This study aims to characterize Wolbachia sp. and determine the association between Wolbachia and canine filarial nematode species in Thailand. A total of 46 dog blood samples that were naturally infected with filarial nematodes were obtained to identify filarial nematode species by Giemsa stained under a light microscope and confirmed using the molecular technique. In order to characterize Wolbachia sp., the nested PCR assay targeting the 16S rRNA gene showed that all samples of Dirofilaria immitis and fifteen samples of Candidatus Dirofilaria hongkongensis were grouped into Wolbachia supergroup C. In addition, all sample...
Source: Acta Tropica - August 11, 2023 Category: Infectious Diseases Authors: Patchana Kamkong Wanarit Jitsamai Kritsada Thongmeesee Panan Ratthawongjirakul Piyanan Taweethavonsawat Source Type: research

Genetic diversity and characterization of Wolbachia endosymbiont in canine filariasis
This study aims to characterize Wolbachia sp. and determine the association between Wolbachia and canine filarial nematode species in Thailand. A total of 46 dog blood samples that were naturally infected with filarial nematodes were obtained to identify filarial nematode species by Giemsa stained under a light microscope and confirmed using the molecular technique. In order to characterize Wolbachia sp., the nested PCR assay targeting the 16S rRNA gene showed that all samples of Dirofilaria immitis and fifteen samples of Candidatus Dirofilaria hongkongensis were grouped into Wolbachia supergroup C. In addition, all sample...
Source: Acta Tropica - August 11, 2023 Category: Infectious Diseases Authors: Patchana Kamkong Wanarit Jitsamai Kritsada Thongmeesee Panan Ratthawongjirakul Piyanan Taweethavonsawat Source Type: research

Soil-transmitted helminths: A critical review of the impact of co-infections and implications for control and elimination
by Sarah Lebu, Winnie Kibone, Chimdi C. Muoghalu, Stephen Ochaya, Aaron Salzberg, Felix Bongomin, Musa Manga Researchers have raised the possibility that soil-transmitted helminth (STH) infections might modify the host ’s immune response against other systemic infections. STH infections can alter the immune response towards type 2 immunity that could then affect the likelihood and severity of other illnesses. However, the importance of co-infections is not completely understood, and the impact and direction of t heir effects vary considerably by infection. This review synthesizes evidence regarding the relevance of STH ...
Source: PLoS Neglected Tropical Diseases - August 10, 2023 Category: Tropical Medicine Authors: Sarah Lebu Source Type: research

Comparative Safety Surveillance of Triple (IDA) Versus Dual Therapy (DA) in Mass Drug Administration for Elimination of Lymphatic Filariasis in Kenya: A Cohort Event Monitoring Study
ConclusionsIvermectin, diethylcarbamazine, and albendazole as a combination is as safe and well tolerated as DA to use in MDA campaigns with no serious life-threatening adverse events. Systemic mild-to-moderate adverse events with a few severe cases and transient adverse events are more common with IDA treatment than with DA treatment. Hence, integrating pharmacovigilance into a MDA program is recommended for the timely detection and management of adverse events. (Source: Drug Safety)
Source: Drug Safety - August 8, 2023 Category: Drugs & Pharmacology Source Type: research

Spatial predictive risk mapping of lymphatic filariasis residual hotspots in American Samoa using demographic and environmental factors
ConclusionThe findings may facilitate more specific targeting of post-MDA surveillance activities by prioritising those areas at higher risk of ongoing transmission. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - July 24, 2023 Category: Tropical Medicine Authors: Angela M. Cadavid Restrepo Source Type: research

Vitellogenin genes are transcribed in Culex quinquefasciatus ovary
CONCLUSIONS: This is the first time that vitellogenin transcripts are observed in mosquito ovaries. Studies to determine if Vg transcripts are translated into proteins and their contribution to the reproductive success of the mosquito need to be further investigated.PMID:37466532 | DOI:10.1590/0074-02760220143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - July 19, 2023 Category: Infectious Diseases Authors: Alexandre S Moura Andr é Luis Costa-da-Silva Pedro S Peixoto Ceres Maciel Andr é F Cardoso Source Type: research

Vitellogenin genes are transcribed in Culex quinquefasciatus ovary
CONCLUSIONS: This is the first time that vitellogenin transcripts are observed in mosquito ovaries. Studies to determine if Vg transcripts are translated into proteins and their contribution to the reproductive success of the mosquito need to be further investigated.PMID:37466532 | DOI:10.1590/0074-02760220143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - July 19, 2023 Category: Infectious Diseases Authors: Alexandre S Moura Andr é Luis Costa-da-Silva Pedro S Peixoto Ceres Maciel Andr é F Cardoso Source Type: research

Vitellogenin genes are transcribed in Culex quinquefasciatus ovary
CONCLUSIONS: This is the first time that vitellogenin transcripts are observed in mosquito ovaries. Studies to determine if Vg transcripts are translated into proteins and their contribution to the reproductive success of the mosquito need to be further investigated.PMID:37466532 | DOI:10.1590/0074-02760220143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - July 19, 2023 Category: Infectious Diseases Authors: Alexandre S Moura Andr é Luis Costa-da-Silva Pedro S Peixoto Ceres Maciel Andr é F Cardoso Source Type: research

Vitellogenin genes are transcribed in Culex quinquefasciatus ovary
CONCLUSIONS: This is the first time that vitellogenin transcripts are observed in mosquito ovaries. Studies to determine if Vg transcripts are translated into proteins and their contribution to the reproductive success of the mosquito need to be further investigated.PMID:37466532 | DOI:10.1590/0074-02760220143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - July 19, 2023 Category: Infectious Diseases Authors: Alexandre S Moura Andr é Luis Costa-da-Silva Pedro S Peixoto Ceres Maciel Andr é F Cardoso Source Type: research

Vitellogenin genes are transcribed in Culex quinquefasciatus ovary
CONCLUSIONS: This is the first time that vitellogenin transcripts are observed in mosquito ovaries. Studies to determine if Vg transcripts are translated into proteins and their contribution to the reproductive success of the mosquito need to be further investigated.PMID:37466532 | DOI:10.1590/0074-02760220143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - July 19, 2023 Category: Infectious Diseases Authors: Alexandre S Moura Andr é Luis Costa-da-Silva Pedro S Peixoto Ceres Maciel Andr é F Cardoso Source Type: research

Vitellogenin genes are transcribed in Culex quinquefasciatus ovary
CONCLUSIONS: This is the first time that vitellogenin transcripts are observed in mosquito ovaries. Studies to determine if Vg transcripts are translated into proteins and their contribution to the reproductive success of the mosquito need to be further investigated.PMID:37466532 | PMC:PMC10368008 | DOI:10.1590/0074-02760220143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - July 19, 2023 Category: Infectious Diseases Authors: Alexandre S Moura Andr é Luis Costa-da-Silva Pedro S Peixoto Ceres Maciel Andr é F Cardoso Source Type: research