Assessment of wing geometric morphometrics of urban Culex quinquefasciatus (Diptera: Culicidae) populations
Acta Trop. 2023 Jun 16:106971. doi: 10.1016/j.actatropica.2023.106971. Online ahead of print.ABSTRACTCulex quinquefasciatus is a cosmopolitan species distributed throughout tropical and subtropical areas of the world. The species is of great epidemiological importance as it is responsible for vectoring the causative agent of lymphatic filariasis and several arboviruses, including West Nile virus. Wing geometric morphometrics has been widely used to assess phenotypic variations in mosquito species. Here, we hypothesize that Cx. quinquefasciatus populations in urban parks in the city of São Paulo, Brazil, have been subjecte...
Source: Acta Tropica - June 18, 2023 Category: Infectious Diseases Authors: Rafael Oliveira-Christe Gabriela Cristina de Carvalho Andr é Barretto Bruno Wilke Mauro Toledo Marrelli Source Type: research
Evaluating the availability and quality of services for lymphatic filariasis morbidity in Ghana
Conclusions and significanceThe findings from this study can help the Ghana NTD Program identify areas of improvement as they seek to achieve LF elimination targets and continue to improve access to care for those with LF-related morbidity as part of overall health systems strengthening. Key recommendations include prioritizing refresher and MMDP training for health workers, ensuring reliable patient tracking systems, and integrating lymphatic filariasis morbidity management into the routine healthcare system to ensure medicine and commodity availably. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - June 12, 2023 Category: Tropical Medicine Authors: Melissa Edmiston Source Type: research
Larvicidal Activities of < em > Allium sativum < /em > L. and < em > Zingiber officinale < /em > Rosc. Extracts against Filariasis Vectors in Hadiya Zone, Ethiopia
In conclusion, A. sativum have a high toxic effect than Z. officinale extract against filariasis vectors in all type of solvents. So using those plant extracts is the best to reduce the risk of the synthetic chemical on nontarget organisms and the environment, in addition to the control of mosquito-borne diseases, but further studies will be conducted to evaluate the toxicity at different stages of the vectors.PMID:37292452 | PMC:PMC10247325 | DOI:10.1155/2023/6636837 (Source: Biomed Res)
Source: Biomed Res - June 9, 2023 Category: Research Authors: Anmut Assemie Temam Gemeda Source Type: research
Larvicidal Activities of < em > Allium sativum < /em > L. and < em > Zingiber officinale < /em > Rosc. Extracts against Filariasis Vectors in Hadiya Zone, Ethiopia
In conclusion, A. sativum have a high toxic effect than Z. officinale extract against filariasis vectors in all type of solvents. So using those plant extracts is the best to reduce the risk of the synthetic chemical on nontarget organisms and the environment, in addition to the control of mosquito-borne diseases, but further studies will be conducted to evaluate the toxicity at different stages of the vectors.PMID:37292452 | PMC:PMC10247325 | DOI:10.1155/2023/6636837 (Source: Biomed Res)
Source: Biomed Res - June 9, 2023 Category: Research Authors: Anmut Assemie Temam Gemeda Source Type: research
Molecules, Vol. 28, Pages 4628: Assessing Boron-Pleuromutilin AN11251 for the Development of Antibacterial Agents
Zhiyang Zou
Pleuromutilins are a group of antibiotics derived from the naturally occurring compound. The recent approval of lefamulin for both intravenous and oral doses in humans to treat community-acquired bacterial pneumonia has prompted investigations in modifying the structure to broaden the antibacterial spectrum, enhance the activity, and improve the pharmacokinetic properties. AN11251 is a C(14)-functionalized pleuromutilin with a boron-containing heterocycle substructure. It was demonstrated to be an anti-Wolbachia agent with therapeutic potential for Onchocerciasis and lymphatic filariasis. Here, the in vitro...
Source: Molecules - June 8, 2023 Category: Chemistry Authors: Ming-Jie Han Miaomiao Pan Genhui Xiao Ying Yuan Shawn Chen Zhiyang Zou Tags: Article Source Type: research
