Biocompatible coatings based on photo-crosslinkable cellulose derivatives
In this study, the synthesis of cellulose-based photoresists by esterification with methacrylic acid anhydride and sorbic acid was investigated. These resists polymerize under UV irradiation in the range of λ = 254 nm to 365 nm, with or concerning the sorbic acid derivative without using an additional photoinitiator. Usability for biomedical applications was demonstrated by investigating the adhesion and viability of a fibrosarcoma cell line (HT-1080). Compared to polystyrene, the material widely used for cell culture dishes, cell adhesion to the biomaterials tested was even stronger, as assessed by a centrifugation assay...
Source: International Journal of Biological Macromolecules - July 31, 2023 Category: Biochemistry Authors: Maximilian Rothammer Philipp Strobel Cordt Zollfrank Corinna Urmann Source Type: research
Biocompatible coatings based on photo-crosslinkable cellulose derivatives
In this study, the synthesis of cellulose-based photoresists by esterification with methacrylic acid anhydride and sorbic acid was investigated. These resists polymerize under UV irradiation in the range of λ = 254 nm to 365 nm, with or concerning the sorbic acid derivative without using an additional photoinitiator. Usability for biomedical applications was demonstrated by investigating the adhesion and viability of a fibrosarcoma cell line (HT-1080). Compared to polystyrene, the material widely used for cell culture dishes, cell adhesion to the biomaterials tested was even stronger, as assessed by a centrifugation assay...
Source: International Journal of Biological Macromolecules - July 31, 2023 Category: Biochemistry Authors: Maximilian Rothammer Philipp Strobel Cordt Zollfrank Corinna Urmann Source Type: research
Larotrectinib treatment for infantile fibrosarcoma in newborns: a case report and literature review
Infantile fibrosarcoma (IFS) is a rare tumor in childhood characterized by a single, localized, painless mass that grows rapidly but has a relatively indolent biological behavior and a favorable prognosis. Eighty-five percent of infantile fibrosarcomas are associated with t (12;15) (p13;25) chromosomal translocation resulting in ETV6-NTRK3 gene fusion, which provides the target for targeted therapy. Here, we report a case of IFS in a newborn with a mass in the left lower extremity confirmed by imaging, histopathological examination, tissue FISH testing, and high-throughput sequencing to detect gene rearrangement. Based on ...
Source: Frontiers in Oncology - July 27, 2023 Category: Cancer & Oncology Source Type: research
Electrospun fibers integrating enzyme-functionalized metal-organic frameworks for postoperative tumor recurrence inhibition and simultaneously wound tissue healing
Int J Biol Macromol. 2023 Jul 17:125876. doi: 10.1016/j.ijbiomac.2023.125876. Online ahead of print.ABSTRACTThe tumor recurrence and infected wound tissue defect are the major clinical challenges after the surgical treatment of primary chest wall cancer. Herein, to address the above issues, blending electrospinning was applied to incorporate glucose oxidase (GOx) loaded Zn/Cu-based bimetallic zeolitic imidazolate frameworks (GOx/BMOFs) into polyurethane (PU) fibers, which were designed for effective cancer therapy with improved wound healing. The release of Cu2+ and GOx could accomplish the conversion from Cu2+ to Cu+ thro...
Source: International Journal of Biological Macromolecules - July 19, 2023 Category: Biochemistry Authors: Chao Wang Guangchao Lv Shiyun Feng Chang Liu Ziqi Song Hui Zhao Yang Li Kaizhong Wang Source Type: research
Electrospun fibers integrating enzyme-functionalized metal-organic frameworks for postoperative tumor recurrence inhibition and simultaneously wound tissue healing
Int J Biol Macromol. 2023 Jul 17:125876. doi: 10.1016/j.ijbiomac.2023.125876. Online ahead of print.ABSTRACTThe tumor recurrence and infected wound tissue defect are the major clinical challenges after the surgical treatment of primary chest wall cancer. Herein, to address the above issues, blending electrospinning was applied to incorporate glucose oxidase (GOx) loaded Zn/Cu-based bimetallic zeolitic imidazolate frameworks (GOx/BMOFs) into polyurethane (PU) fibers, which were designed for effective cancer therapy with improved wound healing. The release of Cu2+ and GOx could accomplish the conversion from Cu2+ to Cu+ thro...
Source: International Journal of Biological Macromolecules - July 19, 2023 Category: Biochemistry Authors: Chao Wang Guangchao Lv Shiyun Feng Chang Liu Ziqi Song Hui Zhao Yang Li Kaizhong Wang Source Type: research
Giardiasis in an infant with fibro sarcoma: A case report
CONCLUSION: It is critical to keep a watch out for this neglected parasite, and suggested samples, particularly stool samples, must be sent for investigation in order to diagnose and manage these cases properly.PMID:37448372 | DOI:10.2174/1871526523666230713141153 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - July 14, 2023 Category: Infectious Diseases Authors: Twishi Shrimali Saumya Srivastava Naila Mohammad Nikhil John Vibhor Tak Rahul Saxena Source Type: research
Giardiasis in an infant with fibro sarcoma: A case report
CONCLUSION: It is critical to keep a watch out for this neglected parasite, and suggested samples, particularly stool samples, must be sent for investigation in order to diagnose and manage these cases properly.PMID:37448372 | DOI:10.2174/1871526523666230713141153 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - July 14, 2023 Category: Infectious Diseases Authors: Twishi Shrimali Saumya Srivastava Naila Mohammad Nikhil John Vibhor Tak Rahul Saxena Source Type: research
Giardiasis in an infant with fibro sarcoma: A case report
CONCLUSION: It is critical to keep a watch out for this neglected parasite, and suggested samples, particularly stool samples, must be sent for investigation in order to diagnose and manage these cases properly.PMID:37448372 | DOI:10.2174/1871526523666230713141153 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - July 14, 2023 Category: Infectious Diseases Authors: Twishi Shrimali Saumya Srivastava Naila Mohammad Nikhil John Vibhor Tak Rahul Saxena Source Type: research
Giardiasis in an infant with fibro sarcoma: A case report
CONCLUSION: It is critical to keep a watch out for this neglected parasite, and suggested samples, particularly stool samples, must be sent for investigation in order to diagnose and manage these cases properly.PMID:37448372 | DOI:10.2174/1871526523666230713141153 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - July 14, 2023 Category: Infectious Diseases Authors: Twishi Shrimali Saumya Srivastava Naila Mohammad Nikhil John Vibhor Tak Rahul Saxena Source Type: research
Giardiasis in an infant with fibro sarcoma: A case report
CONCLUSION: It is critical to keep a watch out for this neglected parasite, and suggested samples, particularly stool samples, must be sent for investigation in order to diagnose and manage these cases properly.PMID:37448372 | DOI:10.2174/1871526523666230713141153 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - July 14, 2023 Category: Infectious Diseases Authors: Twishi Shrimali Saumya Srivastava Naila Mohammad Nikhil John Vibhor Tak Rahul Saxena Source Type: research
Giardiasis in an infant with fibro sarcoma: A case report
CONCLUSION: It is critical to keep a watch out for this neglected parasite, and suggested samples, particularly stool samples, must be sent for investigation in order to diagnose and manage these cases properly.PMID:37448372 | DOI:10.2174/1871526523666230713141153 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - July 14, 2023 Category: Infectious Diseases Authors: Twishi Shrimali Saumya Srivastava Naila Mohammad Nikhil John Vibhor Tak Rahul Saxena Source Type: research
Giardiasis in an infant with fibro sarcoma: A case report
CONCLUSION: It is critical to keep a watch out for this neglected parasite, and suggested samples, particularly stool samples, must be sent for investigation in order to diagnose and manage these cases properly.PMID:37448372 | DOI:10.2174/1871526523666230713141153 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - July 14, 2023 Category: Infectious Diseases Authors: Twishi Shrimali Saumya Srivastava Naila Mohammad Nikhil John Vibhor Tak Rahul Saxena Source Type: research
Giardiasis in an infant with fibro sarcoma: A case report
CONCLUSION: It is critical to keep a watch out for this neglected parasite, and suggested samples, particularly stool samples, must be sent for investigation in order to diagnose and manage these cases properly.PMID:37448372 | DOI:10.2174/1871526523666230713141153 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - July 14, 2023 Category: Infectious Diseases Authors: Twishi Shrimali Saumya Srivastava Naila Mohammad Nikhil John Vibhor Tak Rahul Saxena Source Type: research
Giardiasis in an infant with fibro sarcoma: A case report
CONCLUSION: It is critical to keep a watch out for this neglected parasite, and suggested samples, particularly stool samples, must be sent for investigation in order to diagnose and manage these cases properly.PMID:37448372 | DOI:10.2174/1871526523666230713141153 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - July 14, 2023 Category: Infectious Diseases Authors: Twishi Shrimali Saumya Srivastava Naila Mohammad Nikhil John Vibhor Tak Rahul Saxena Source Type: research
