The impact of chronic fentanyl administration on the cerebral cortex in mice: Molecular and histological effects
CONCLUSION: Fentanyl administration induced neurotoxic effects in the mouse cerebral cortex that could be primarily mediated by the evoked oxidative-inflammatory response. The altered expression of NMDA receptors, dopamine receptors, and EGF suggests the pernicious effects of fentanyl addiction that may end in the development of toxic psychosis.PMID:38428507 | DOI:10.1016/j.brainresbull.2024.110917 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - March 1, 2024 Category: Neurology Authors: Ayman Alzu'bi Worood Bani Baker Bahaa Al-Trad Mazhar Salim Al Zoubi Manal Isam AbuAlArjah Ejlal Abu-El-Rub Lena Tahat Ahmed Mnz Helaly Doaa S Ghorab Waseem El-Huneidi Raed M Al-Zoubi Source Type: research
Fentanyl/Ketamine
(Source: Reactions Weekly)
Source: Reactions Weekly - March 1, 2024 Category: Drugs & Pharmacology Source Type: research
Calls to Poison Centers Involving Psilocybin on the Rise Among Young People
Since 2019, calls to U.S. poison centers involving youth or young adults who took the psychedelic psilocybin have risen sharply, according to astudy published today in theJournal of Adolescent Health. The timing is notable as 2019 was the start of apsilocybin decriminalization movement across numerous states and cities.Rita Farah, Ph.D., and colleagues at the University of Virginia School of Medicine analyzed data from the National Poison Data System, which collects de-identified poison exposure data from centers across the country. The researchers examined all cases of psilocybin exposure between 2013 and 2022 involving y...
Source: Psychiatr News - February 26, 2024 Category: Psychiatry Tags: adolescents decriminalization poison call poison exposure psilocybin psychedelic young adults Source Type: research
Developing mathematical models to compare and analyse the pharmacokinetics of morphine and fentanyl
CONCLUSION: These comparative mathematical models on morphine and fentanyl enable the determination of drug dosages and understanding of drug efficacy that facilitates optimising dosing regimens. The right choice between them can be made based on the time to reach the target therapeutic concentration in the blood, elimination time, severity of pain, and patient characteristics.PMID:38406346 | PMC:PMC10893797 | DOI:10.4103/ija.ija_1036_23 (Source: Cancer Control)
Source: Cancer Control - February 26, 2024 Category: Cancer & Oncology Authors: Prathvi Shenoy Mahadev Rao Shreesha Chokkadi Sushma Bhatnagar Naveen Salins Source Type: research
Efficacy of Supplemental Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block in Patients Receiving Local Infiltration Analgesia after Hip Fracture Surgery: A Prospective Randomized Controlled Trial
Conclusions: The combination of PENG and LFCN blocks may contribute to enhanced recovery for patients undergoing LIA after hip fracture surgery. However, further well-controlled research is necessary to determine the effectiveness of supplemental PENG combined with LFCN block in addressing cognitive deficits in these patients.PMID:38399602 | PMC:PMC10889980 | DOI:10.3390/medicina60020315 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - February 24, 2024 Category: Universities & Medical Training Authors: Seung-Hee Yoo Min-Jin Lee Min-Hyouk Beak Won-Joong Kim Source Type: research
Efficacy of Supplemental Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block in Patients Receiving Local Infiltration Analgesia after Hip Fracture Surgery: A Prospective Randomized Controlled Trial
Conclusions: The combination of PENG and LFCN blocks may contribute to enhanced recovery for patients undergoing LIA after hip fracture surgery. However, further well-controlled research is necessary to determine the effectiveness of supplemental PENG combined with LFCN block in addressing cognitive deficits in these patients.PMID:38399602 | PMC:PMC10889980 | DOI:10.3390/medicina60020315 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - February 24, 2024 Category: Universities & Medical Training Authors: Seung-Hee Yoo Min-Jin Lee Min-Hyouk Beak Won-Joong Kim Source Type: research
Efficacy of Supplemental Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block in Patients Receiving Local Infiltration Analgesia after Hip Fracture Surgery: A Prospective Randomized Controlled Trial
Conclusions: The combination of PENG and LFCN blocks may contribute to enhanced recovery for patients undergoing LIA after hip fracture surgery. However, further well-controlled research is necessary to determine the effectiveness of supplemental PENG combined with LFCN block in addressing cognitive deficits in these patients.PMID:38399602 | PMC:PMC10889980 | DOI:10.3390/medicina60020315 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - February 24, 2024 Category: Universities & Medical Training Authors: Seung-Hee Yoo Min-Jin Lee Min-Hyouk Beak Won-Joong Kim Source Type: research
Efficacy of Supplemental Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block in Patients Receiving Local Infiltration Analgesia after Hip Fracture Surgery: A Prospective Randomized Controlled Trial
Conclusions: The combination of PENG and LFCN blocks may contribute to enhanced recovery for patients undergoing LIA after hip fracture surgery. However, further well-controlled research is necessary to determine the effectiveness of supplemental PENG combined with LFCN block in addressing cognitive deficits in these patients.PMID:38399602 | PMC:PMC10889980 | DOI:10.3390/medicina60020315 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - February 24, 2024 Category: Universities & Medical Training Authors: Seung-Hee Yoo Min-Jin Lee Min-Hyouk Beak Won-Joong Kim Source Type: research
Efficacy of Supplemental Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block in Patients Receiving Local Infiltration Analgesia after Hip Fracture Surgery: A Prospective Randomized Controlled Trial
Conclusions: The combination of PENG and LFCN blocks may contribute to enhanced recovery for patients undergoing LIA after hip fracture surgery. However, further well-controlled research is necessary to determine the effectiveness of supplemental PENG combined with LFCN block in addressing cognitive deficits in these patients.PMID:38399602 | PMC:PMC10889980 | DOI:10.3390/medicina60020315 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - February 24, 2024 Category: Universities & Medical Training Authors: Seung-Hee Yoo Min-Jin Lee Min-Hyouk Beak Won-Joong Kim Source Type: research
Efficacy of Supplemental Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block in Patients Receiving Local Infiltration Analgesia after Hip Fracture Surgery: A Prospective Randomized Controlled Trial
Conclusions: The combination of PENG and LFCN blocks may contribute to enhanced recovery for patients undergoing LIA after hip fracture surgery. However, further well-controlled research is necessary to determine the effectiveness of supplemental PENG combined with LFCN block in addressing cognitive deficits in these patients.PMID:38399602 | PMC:PMC10889980 | DOI:10.3390/medicina60020315 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - February 24, 2024 Category: Universities & Medical Training Authors: Seung-Hee Yoo Min-Jin Lee Min-Hyouk Beak Won-Joong Kim Source Type: research
Efficacy of Supplemental Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block in Patients Receiving Local Infiltration Analgesia after Hip Fracture Surgery: A Prospective Randomized Controlled Trial
Conclusions: The combination of PENG and LFCN blocks may contribute to enhanced recovery for patients undergoing LIA after hip fracture surgery. However, further well-controlled research is necessary to determine the effectiveness of supplemental PENG combined with LFCN block in addressing cognitive deficits in these patients.PMID:38399602 | PMC:PMC10889980 | DOI:10.3390/medicina60020315 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - February 24, 2024 Category: Universities & Medical Training Authors: Seung-Hee Yoo Min-Jin Lee Min-Hyouk Beak Won-Joong Kim Source Type: research
Efficacy of Supplemental Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block in Patients Receiving Local Infiltration Analgesia after Hip Fracture Surgery: A Prospective Randomized Controlled Trial
Conclusions: The combination of PENG and LFCN blocks may contribute to enhanced recovery for patients undergoing LIA after hip fracture surgery. However, further well-controlled research is necessary to determine the effectiveness of supplemental PENG combined with LFCN block in addressing cognitive deficits in these patients.PMID:38399602 | PMC:PMC10889980 | DOI:10.3390/medicina60020315 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - February 24, 2024 Category: Universities & Medical Training Authors: Seung-Hee Yoo Min-Jin Lee Min-Hyouk Beak Won-Joong Kim Source Type: research
Efficacy of Supplemental Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block in Patients Receiving Local Infiltration Analgesia after Hip Fracture Surgery: A Prospective Randomized Controlled Trial
Conclusions: The combination of PENG and LFCN blocks may contribute to enhanced recovery for patients undergoing LIA after hip fracture surgery. However, further well-controlled research is necessary to determine the effectiveness of supplemental PENG combined with LFCN block in addressing cognitive deficits in these patients.PMID:38399602 | PMC:PMC10889980 | DOI:10.3390/medicina60020315 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - February 24, 2024 Category: Universities & Medical Training Authors: Seung-Hee Yoo Min-Jin Lee Min-Hyouk Beak Won-Joong Kim Source Type: research
Efficacy of Supplemental Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block in Patients Receiving Local Infiltration Analgesia after Hip Fracture Surgery: A Prospective Randomized Controlled Trial
Conclusions: The combination of PENG and LFCN blocks may contribute to enhanced recovery for patients undergoing LIA after hip fracture surgery. However, further well-controlled research is necessary to determine the effectiveness of supplemental PENG combined with LFCN block in addressing cognitive deficits in these patients.PMID:38399602 | PMC:PMC10889980 | DOI:10.3390/medicina60020315 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - February 24, 2024 Category: Universities & Medical Training Authors: Seung-Hee Yoo Min-Jin Lee Min-Hyouk Beak Won-Joong Kim Source Type: research
