In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.ABSTRACTA hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive high cumulative doses for daily analgosedation and often already have impaired liver function due to an underlying disease or complications during treatment. A well-established biosensor based on HepG2/C3A cells was used for the determination of the hepatotoxicity of commonly used sedatives an...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Katharina Haller Sandra Do ß Martin Sauer Source Type: research
In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.ABSTRACTA hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive high cumulative doses for daily analgosedation and often already have impaired liver function due to an underlying disease or complications during treatment. A well-established biosensor based on HepG2/C3A cells was used for the determination of the hepatotoxicity of commonly used sedatives an...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Katharina Haller Sandra Do ß Martin Sauer Source Type: research
In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.ABSTRACTA hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive high cumulative doses for daily analgosedation and often already have impaired liver function due to an underlying disease or complications during treatment. A well-established biosensor based on HepG2/C3A cells was used for the determination of the hepatotoxicity of commonly used sedatives an...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Katharina Haller Sandra Do ß Martin Sauer Source Type: research
In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.ABSTRACTA hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive high cumulative doses for daily analgosedation and often already have impaired liver function due to an underlying disease or complications during treatment. A well-established biosensor based on HepG2/C3A cells was used for the determination of the hepatotoxicity of commonly used sedatives an...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Katharina Haller Sandra Do ß Martin Sauer Source Type: research
The efficacy of rhomboid intercostal block for pain management after video-assisted thoracoscopic surgery: a prospective, randomized-controlled trial
ConclusionUS-guided RIB provides effective post-VATS analgesia. (Source: General Thoracic and Cardiovascular Surgery)
Source: General Thoracic and Cardiovascular Surgery - April 26, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research
Transdermal Opioids and the Quality of Life of the Cancer Patient: A Systematic Literature Review
CONCLUSIONS: Transdermal therapy was suggested to have several advantages over oral opioid therapy in enhancing cancer patients' QoL. These benefits span various dimensions, including pain management, physical functioning, mental health, vitality, overall patient improvement, anger/aversion, strength/activity, general QoL, cognitive and emotional functions, fatigue, and insomnia.PMID:38659244 | DOI:10.1177/10600280241247363 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - April 25, 2024 Category: Drugs & Pharmacology Authors: Patricia Santos Reis Durval Campos Kraychete Emilie de Magalh ães Pedreira Eduardo Silva Reis Barreto C ésar Romero Antunes Júnior Vinicius Borges Alencar Anna Karla do Nascimento Souza Liliane Elze Falc ão Lins-Kusterer Liana Maria Torres de Araujo A Source Type: research
Black Americans' Drug Mortality Increases and Local Employment Opportunities, 2010 ‒2021
Conclusions. Increasing employment opportunities can be an important strategy for preventing Black Americans' drug mortality, especially among those living in areas with higher increases in fentanyl seizure rates. (Am J Public Health. Published online ahead of print April 25, 2024:e1-e4. https://doi.org/10.2105/AJPH.2024.307646).PMID:38662973 | DOI:10.2105/AJPH.2024.307646 (Source: American Journal of Public Health)
Source: American Journal of Public Health - April 25, 2024 Category: International Medicine & Public Health Authors: Sehun Oh Manuel Cano Source Type: research
Black Americans' Drug Mortality Increases and Local Employment Opportunities, 2010 ‒2021
Conclusions. Increasing employment opportunities can be an important strategy for preventing Black Americans' drug mortality, especially among those living in areas with higher increases in fentanyl seizure rates. (Am J Public Health. Published online ahead of print April 25, 2024:e1-e4. https://doi.org/10.2105/AJPH.2024.307646).PMID:38662973 | DOI:10.2105/AJPH.2024.307646 (Source: Am J Public Health)
Source: Am J Public Health - April 25, 2024 Category: International Medicine & Public Health Authors: Sehun Oh Manuel Cano Source Type: research
Transdermal Opioids and the Quality of Life of the Cancer Patient: A Systematic Literature Review
CONCLUSIONS: Transdermal therapy was suggested to have several advantages over oral opioid therapy in enhancing cancer patients' QoL. These benefits span various dimensions, including pain management, physical functioning, mental health, vitality, overall patient improvement, anger/aversion, strength/activity, general QoL, cognitive and emotional functions, fatigue, and insomnia.PMID:38659244 | DOI:10.1177/10600280241247363 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - April 25, 2024 Category: Drugs & Pharmacology Authors: Patricia Santos Reis Durval Campos Kraychete Emilie de Magalh ães Pedreira Eduardo Silva Reis Barreto C ésar Romero Antunes Júnior Vinicius Borges Alencar Anna Karla do Nascimento Souza Liliane Elze Falc ão Lins-Kusterer Liana Maria Torres de Araujo A Source Type: research
Black Americans' Drug Mortality Increases and Local Employment Opportunities, 2010 ‒2021
Conclusions. Increasing employment opportunities can be an important strategy for preventing Black Americans' drug mortality, especially among those living in areas with higher increases in fentanyl seizure rates. (Am J Public Health. Published online ahead of print April 25, 2024:e1-e4. https://doi.org/10.2105/AJPH.2024.307646).PMID:38662973 | DOI:10.2105/AJPH.2024.307646 (Source: American Journal of Public Health)
Source: American Journal of Public Health - April 25, 2024 Category: International Medicine & Public Health Authors: Sehun Oh Manuel Cano Source Type: research
Black Americans' Drug Mortality Increases and Local Employment Opportunities, 2010 ‒2021
Conclusions. Increasing employment opportunities can be an important strategy for preventing Black Americans' drug mortality, especially among those living in areas with higher increases in fentanyl seizure rates. (Am J Public Health. Published online ahead of print April 25, 2024:e1-e4. https://doi.org/10.2105/AJPH.2024.307646).PMID:38662973 | DOI:10.2105/AJPH.2024.307646 (Source: Am J Public Health)
Source: Am J Public Health - April 25, 2024 Category: International Medicine & Public Health Authors: Sehun Oh Manuel Cano Source Type: research
Transdermal Opioids and the Quality of Life of the Cancer Patient: A Systematic Literature Review
CONCLUSIONS: Transdermal therapy was suggested to have several advantages over oral opioid therapy in enhancing cancer patients' QoL. These benefits span various dimensions, including pain management, physical functioning, mental health, vitality, overall patient improvement, anger/aversion, strength/activity, general QoL, cognitive and emotional functions, fatigue, and insomnia.PMID:38659244 | DOI:10.1177/10600280241247363 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - April 25, 2024 Category: Drugs & Pharmacology Authors: Patricia Santos Reis Durval Campos Kraychete Emilie de Magalh ães Pedreira Eduardo Silva Reis Barreto C ésar Romero Antunes Júnior Vinicius Borges Alencar Anna Karla do Nascimento Souza Liliane Elze Falc ão Lins-Kusterer Liana Maria Torres de Araujo A Source Type: research
Black Americans' Drug Mortality Increases and Local Employment Opportunities, 2010 ‒2021
Conclusions. Increasing employment opportunities can be an important strategy for preventing Black Americans' drug mortality, especially among those living in areas with higher increases in fentanyl seizure rates. (Am J Public Health. Published online ahead of print April 25, 2024:e1-e4. https://doi.org/10.2105/AJPH.2024.307646).PMID:38662973 | DOI:10.2105/AJPH.2024.307646 (Source: American Journal of Public Health)
Source: American Journal of Public Health - April 25, 2024 Category: International Medicine & Public Health Authors: Sehun Oh Manuel Cano Source Type: research
Black Americans' Drug Mortality Increases and Local Employment Opportunities, 2010 ‒2021
Conclusions. Increasing employment opportunities can be an important strategy for preventing Black Americans' drug mortality, especially among those living in areas with higher increases in fentanyl seizure rates. (Am J Public Health. Published online ahead of print April 25, 2024:e1-e4. https://doi.org/10.2105/AJPH.2024.307646).PMID:38662973 | DOI:10.2105/AJPH.2024.307646 (Source: Am J Public Health)
Source: Am J Public Health - April 25, 2024 Category: International Medicine & Public Health Authors: Sehun Oh Manuel Cano Source Type: research
Transdermal Opioids and the Quality of Life of the Cancer Patient: A Systematic Literature Review
CONCLUSIONS: Transdermal therapy was suggested to have several advantages over oral opioid therapy in enhancing cancer patients' QoL. These benefits span various dimensions, including pain management, physical functioning, mental health, vitality, overall patient improvement, anger/aversion, strength/activity, general QoL, cognitive and emotional functions, fatigue, and insomnia.PMID:38659244 | DOI:10.1177/10600280241247363 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - April 25, 2024 Category: Drugs & Pharmacology Authors: Patricia Santos Reis Durval Campos Kraychete Emilie de Magalh ães Pedreira Eduardo Silva Reis Barreto C ésar Romero Antunes Júnior Vinicius Borges Alencar Anna Karla do Nascimento Souza Liliane Elze Falc ão Lins-Kusterer Liana Maria Torres de Araujo A Source Type: research
