The role of human C5a as a non-genomic target in corticosteroid therapy for management of severe COVID19
Comput Biol Chem. 2021 Apr 5;92:107482. doi: 10.1016/j.compbiolchem.2021.107482. Online ahead of print.ABSTRACTComplement system plays a dual role; physiological as well as pathophysiological. While physiological role protects the host, pathophysiological role can substantially harm the host, by triggering several hyper-inflammatory pathways, referred as "hypercytokinaemia". Emerging clinical evidence suggests that exposure to severe acute respiratory syndrome coronavirus-2 (SARS-CoV2), tricks the complement to aberrantly activate the "hypercytokinaemia" loop, which significantly contributes to the severity of the COVID19....
Source: Computational Biology and Chemistry - April 12, 2021 Category: Bioinformatics Authors: Aurosikha Das Soumendra Rana Source Type: research
The role of human C5a as a non-genomic target in corticosteroid therapy for management of severe COVID19
Comput Biol Chem. 2021 Apr 5;92:107482. doi: 10.1016/j.compbiolchem.2021.107482. Online ahead of print.ABSTRACTComplement system plays a dual role; physiological as well as pathophysiological. While physiological role protects the host, pathophysiological role can substantially harm the host, by triggering several hyper-inflammatory pathways, referred as "hypercytokinaemia". Emerging clinical evidence suggests that exposure to severe acute respiratory syndrome coronavirus-2 (SARS-CoV2), tricks the complement to aberrantly activate the "hypercytokinaemia" loop, which significantly contributes to the severity of the COVID19....
Source: Computational Biology and Chemistry - April 12, 2021 Category: Bioinformatics Authors: Aurosikha Das Soumendra Rana Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
Stability of Six Drugs in Total Parenteral Nutrition Solution
In this study, we investigated the stability of six drugs, including famotidine, scopolamine butylbromide, furosemide, bromhexine hydrochloride, betamethasone sodium phosphate, and metoclopramide hydrochloride in the infusion bags under dark conditions at 4℃ for 7 days. Additionally, we developed a high-performance liquid chromatography method to determine drug concentrations in the infusions. The concentrations of injected famotidine, scopolamine butylbromide, and betamethasone sodium phosphate remained unchanged when the four chambers of Elneopa NF No. 1 and No. 2 were opened and the infusions were mixed. Their respect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 1, 2021 Category: Drugs & Pharmacology Authors: Takefumi Kumagai Naoko Narahara Eiji Sato Yoshitaka Kihira Yoshino Fujimura Eijiro Kojima Shojiro Ogawa Yuko Date Yasuto Tsuruta Hironori Yoshitomi Hirofumi Inoue Source Type: research
