Herbal Supplements
The Food and Drug Administration (FDA) classifies herbal preparations as food supplements. New herbal supplements and products are not governed by the strict FDA drug approval process and there is no premarket approval required. The FDA prohibits manufacturers and distributors from marketing adulterated or misbranded products but does not rigorously define safe practices. Scientific evidence related to herbal supplements is limited. Herbal supplements have been associated with adverse reactions and herbal-drug interactions. Information and precautions for 20 common herbal supplements, including St. John ’s wort, ginseng,...
Source: Nursing Clinics of North America - December 28, 2020 Category: Nursing Authors: Christopher Ty Williams Source Type: research
The Use of Nanostructured Gibberellic Acid to Optimize the Cultivation of Echinacea purpurea (L.) Moench In Vi
(Source: Journal of Computational and Theoretical Nanoscience)
Source: Journal of Computational and Theoretical Nanoscience - December 19, 2020 Category: Nanotechnology Authors: Maslova, Elena V. Krolevets, Alexander A. Gaidai, Polina A. Kalashnikova, Elena A. Cherednichenko, Mikhail Y. Kirakosyan, Rima N. Perelygina, Tatyana A. Tags: research-article Source Type: research
Biochemometric Analysis of Fatty Acid Amide Hydrolase Inhibition by Echinacea Root Extracts
In this study, we investigated the in vitro inhibitory effect of root extracts of Echinacea purpurea and Echinacea angustifolia on fatty acid amide hydrolase, the main enzyme that degrades the endocannabinoid anandamide. The objective was to relate variation in bioactivity between commercial Echinacea genotypes to their phytochemical profiles and to identify determinants of activity using biochemometric analysis. Forty root extracts of each of species were tested for inhibition of fatty acid amide hydrolase and analyzed by HPLC-DAD/MS to identify and quantitate alkylamides and caffeic acid derivatives. Fatty acid amide hyd...
Source: Planta Medica - December 9, 2020 Category: Drugs & Pharmacology Authors: Liu, Rui Burkett, Kelly Rapinski, Michel Arnason, John T. Johnson, Franklin Hintz, Phil Baker, John Harris, Cory S. Tags: Original Papers Source Type: research
Correction to: Indirect somatic embryogenesis of purple coneflower (Echinacea purpurea (L.) Moench): a medicinal ‑ornamental plant: evaluation of antioxidant enzymes activity and histological study.
Correction to: Indirect somatic embryogenesis of purple coneflower (Echinacea purpurea (L.) Moench): a medicinal‑ornamental plant: evaluation of antioxidant enzymes activity and histological study.
Mol Biol Rep. 2020 Nov 24;:
Authors: Dehestani-Ardakani M, Hejazi M, Aliabad KK
Abstract
The article Indirect somatic embryogenesis of purple coneflower (Echinacea purpurea (L.) Moench): a medicinal‑ornamental plant: evaluation of antioxidant enzymes activity and histological study written by Maryam Dehestani-Ardakani, Mohadeseh Hejazi, Kazem Kamali Aliabad, was originally published...
Source: Molecular Biology Reports - November 24, 2020 Category: Molecular Biology Authors: Dehestani-Ardakani M, Hejazi M, Aliabad KK Tags: Mol Biol Rep Source Type: research
Author Correction: In vitro virucidal activity of Echinaforce ®, an Echinacea purpurea preparation, against coronaviruses, including common cold coronavirus 229E and SARS-CoV-2
The original version of the acknowledgement unfortunately contained a mistake. (Source: Virology Journal)
Source: Virology Journal - November 9, 2020 Category: Virology Authors: Johanna Signer, Hulda R. Jonsdottir, Werner C. Albrich, Marc Strasser, Roland Z üst, Sarah Ryter, Rahel Ackermann-Gäumann, Nicole Lenz, Denise Siegrist, Andreas Suter, Roland Schoop and Olivier B. Engler Tags: Author Correction Source Type: research
Molecules, Vol. 25, Pages 5142: Comparison of Maceration and Ultrasonication for Green Extraction of Phenolic Acids from Echinacea purpurea Aerial Parts
In this study, the efficiency of traditional maceration using water and ethanol was compared with the maceration using mixtures of water and glycerol, a non-toxic, biodegradable solvent from renewable sources. It was found that the glycerol–water mixtures were as effective as ethanol/water mixtures for the extraction of caffeic acid derivatives. All the prepared extracts demonstrated notable antiradical properties. Furthermore, an efficient ultrasound-assisted extraction using glycerol–water mixtures was developed using six independent variables. Their levels needed for the maximum extraction of...
Source: Molecules - November 5, 2020 Category: Chemistry Authors: Plamen Momchev Petar Ciganovi ć Mario Jug Eva Margu í Jasna Jablan Marijana Zovko Kon čić Tags: Article Source Type: research
Traditional Herbal Medicine Candidates as Complementary Treatments for COVID-19: A Review of Their Mechanisms, Pros and Cons.
Authors: Nugraha RV, Ridwansyah H, Ghozali M, Khairani AF, Atik N
Abstract
Coronavirus disease 2019 (COVID-19) is a new infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that belongs to the coronavirus family. The first case was reported in December 2019, and the disease has become a pandemic. Impaired immune regulation is one of the factors that play a role in its pathogenesis and results in poor outcomes of COVID-19 patients. There have been many studies with drug candidates used as antivirals or immunomodulators. However, the results of these investigations showed...
Source: Evidence-based Complementary and Alternative Medicine - October 27, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Oral echinacea for prevention of relapses of molluscum contagiosum.
Authors: Veraldi S, Santambroggio A, Schianchi R, Carminati G, Benzecry V
PMID: 33016668 [PubMed - as supplied by publisher] (Source: Giornale Italiano di Dermatologia e Venereologia)
Source: Giornale Italiano di Dermatologia e Venereologia - October 7, 2020 Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
Effect of Sublethal Blue Light on Herbal Extract Activity Against Volatile Sulfide Compound Production by Fusobacterium nucleatum
Oral malodor is a common and disturbing condition affecting some 25% of adult population. In most cases, the malodor results from the activity of proteolytic oral bacteria such asFusobacterium nucleatum. In a previous study, we have shown that sublethal dosage of high ‐intensity blue light can induce cell membrane damage inFusobacterium nucleatum. In the present study, we tested the hypothesis that the resulting increased cell membrane permeability may increase the efficacy of antimalodor agents. Taken together, the results of the present study suggest that sublethal blue light may increase the efficacy of antimalodor he...
Source: Photochemistry and Photobiology - September 25, 2020 Category: Science Authors: Uziel Jeffet,
Neta Dagan,
Nir Sterer Tags: Research Article Source Type: research
COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?
ConclusionsOur work suggests that several herbal medicines have safety margins superior to those of reference drugs and enough levels of evidence to start a clinical discussion about their potential use as adjuvants in the treatment of early/mild common flu in otherwise healthy adults within the context of COVID-19. While these herbal medicines will not cure or prevent the flu, they may both improve general patient well-being and offer them an opportunity to personalize the therapeutic approaches. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - September 22, 2020 Category: Drugs & Pharmacology Source Type: research
Echinacea Angustifolia DC Extract Induces Apoptosis and Cell Cycle Arrest and Synergizes with Paclitaxel in the MDA-MB-231 and MCF-7 Human Breast Cancer Cell Lines
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - September 21, 2020 Category: Cancer & Oncology Authors: Daniel Abraham Espinosa-Paredes Jorge Cornejo-Garrido Mario Ad án Moreno-Eutimio Oswaldo Pablo Mart ínez-Rodríguez Mar ía Eugenia Jaramillo-Flores Cynthia Ordaz-Pichardo Source Type: research
Echinacea Angustifolia DC Extract Induces Apoptosis and Cell Cycle Arrest and Synergizes with Paclitaxel in the MDA-MB-231 and MCF-7 Human Breast Cancer Cell Lines.
CONCLUSION: The Ea-AcOEt extract is a potential candidate for breast cancer treatment.
PMID: 32959676 [PubMed - as supplied by publisher] (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - September 21, 2020 Category: Cancer & Oncology Authors: Espinosa-Paredes DA, Cornejo-Garrido J, Moreno-Eutimio MA, Martínez-Rodríguez OP, Jaramillo-Flores ME, Ordaz-Pichardo C Tags: Nutr Cancer Source Type: research
