Immunomodulatory Effect of Phytoactive Compounds on Human Health: A Narrative Review Integrated with Bioinformatics Approach
CONCLUSION: The present study presents a cumulative picture of phytochemicals with therapeutic benefits. Additionally, the study also reported a few novel genes and pathways in Echinacea extracts by re-analyzing GSE 12259, indicating its anti-inflammatory, anti-viral, and immunomodulatory properties.PMID:38551050 | DOI:10.2174/0115680266274272240321065039 (Source: Current Topics in Medicinal Chemistry)
Source: Current Topics in Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Saumya Choudhary Sheeba Khan Shivani Rustagi Vijay Rani Rajpal Noor Saba Khan Neeraj Kumar George Thomas Anamika Pandey Mehmet Hamurcu Sait Gezgin Sajad Majeed Zargar Mohd Kamran Khan Source Type: research
Immunomodulatory Effect of Phytoactive Compounds on Human Health: A Narrative Review Integrated with Bioinformatics Approach
CONCLUSION: The present study presents a cumulative picture of phytochemicals with therapeutic benefits. Additionally, the study also reported a few novel genes and pathways in Echinacea extracts by re-analyzing GSE 12259, indicating its anti-inflammatory, anti-viral, and immunomodulatory properties.PMID:38551050 | DOI:10.2174/0115680266274272240321065039 (Source: Current Topics in Medicinal Chemistry)
Source: Current Topics in Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Saumya Choudhary Sheeba Khan Shivani Rustagi Vijay Rani Rajpal Noor Saba Khan Neeraj Kumar George Thomas Anamika Pandey Mehmet Hamurcu Sait Gezgin Sajad Majeed Zargar Mohd Kamran Khan Source Type: research
Immunomodulatory Effect of Phytoactive Compounds on Human Health: A Narrative Review Integrated with Bioinformatics Approach
CONCLUSION: The present study presents a cumulative picture of phytochemicals with therapeutic benefits. Additionally, the study also reported a few novel genes and pathways in Echinacea extracts by re-analyzing GSE 12259, indicating its anti-inflammatory, anti-viral, and immunomodulatory properties.PMID:38551050 | DOI:10.2174/0115680266274272240321065039 (Source: Current Topics in Medicinal Chemistry)
Source: Current Topics in Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Saumya Choudhary Sheeba Khan Shivani Rustagi Vijay Rani Rajpal Noor Saba Khan Neeraj Kumar George Thomas Anamika Pandey Mehmet Hamurcu Sait Gezgin Sajad Majeed Zargar Mohd Kamran Khan Source Type: research
Immunomodulatory Effect of Phytoactive Compounds on Human Health: A Narrative Review Integrated with Bioinformatics Approach
CONCLUSION: The present study presents a cumulative picture of phytochemicals with therapeutic benefits. Additionally, the study also reported a few novel genes and pathways in Echinacea extracts by re-analyzing GSE 12259, indicating its anti-inflammatory, anti-viral, and immunomodulatory properties.PMID:38551050 | DOI:10.2174/0115680266274272240321065039 (Source: Cancer Control)
Source: Cancer Control - March 29, 2024 Category: Cancer & Oncology Authors: Saumya Choudhary Sheeba Khan Shivani Rustagi Vijay Rani Rajpal Noor Saba Khan Neeraj Kumar George Thomas Anamika Pandey Mehmet Hamurcu Sait Gezgin Sajad Majeed Zargar Mohd Kamran Khan Source Type: research
Immunomodulatory Effect of Phytoactive Compounds on Human Health: A Narrative Review Integrated with Bioinformatics Approach
CONCLUSION: The present study presents a cumulative picture of phytochemicals with therapeutic benefits. Additionally, the study also reported a few novel genes and pathways in Echinacea extracts by re-analyzing GSE 12259, indicating its anti-inflammatory, anti-viral, and immunomodulatory properties.PMID:38551050 | DOI:10.2174/0115680266274272240321065039 (Source: Current Topics in Medicinal Chemistry)
Source: Current Topics in Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Saumya Choudhary Sheeba Khan Shivani Rustagi Vijay Rani Rajpal Noor Saba Khan Neeraj Kumar George Thomas Anamika Pandey Mehmet Hamurcu Sait Gezgin Sajad Majeed Zargar Mohd Kamran Khan Source Type: research
Echinacea purpurea root extract mitigates hepatotoxicity, genotoxicity, and ultrastructural changes induced by hexavalent chromium via oxidative stress suppression
Environ Sci Pollut Res Int. 2024 Mar 8. doi: 10.1007/s11356-024-32763-7. Online ahead of print.ABSTRACTEnvironmental and occupational exposure to hexavalent chromium (CrVI) is mostly renowned as a possible hepatotoxic in mammals. Echinacea purpurea (L.) Moench, a phenolic-rich plant, is recurrently used for its therapeutic properties. Therefore, this investigation was done to explore whether E. purpurea (EP) root extract would have any potential health benefits against an acute dose of CrVI-induced oxidative damage and hepatotoxicity. Results revealed that GC-MS analysis of EP root extract has 26 identified components with...
Source: Environmental Science and Pollution Research International - March 8, 2024 Category: Environmental Health Authors: Fatma M El-Demerdash Mustafa M Karhib Nora F Ghanem Mohamed M Abdel-Daim Raghda A El-Sayed Source Type: research
Molecules, Vol. 29, Pages 971: Analytical Assessment of the Antioxidant Properties of the Coneflower (Echinacea purpurea L. Moench) Grown with Various Mulch Materials
This study was carried out to determine the antioxidant properties of flowers and plant stems with leaves of Echinacea purpurea grown with mulches of different colours and thicknesses. Coneflowers were grown in the Experimental Station of the Agricultural University in Kraków, Poland. The mulching materials used were black, green and brown colours of 100 g/m2 and 80 g/m2 density. In plant material, e.g., flowers or plant stems plus leaves the proximate analysis, the total polyphenol content and the ability to scavenge free radicals (ABTS, DPPH and FRAP) were determined. The results show that flower samples h...
Source: Molecules - February 22, 2024 Category: Chemistry Authors: Celestina Adebimpe Ojo Kinga Dziadek Urszula Sadowska Joanna Skoczylas Aneta Kope ć Tags: Article Source Type: research
Development of full-length infectious cDNA clones and host range identification of an echinacea strain of tobacco streak virus
Virology. 2024 Feb 11;593:110013. doi: 10.1016/j.virol.2024.110013. Online ahead of print.ABSTRACTTobacco streak virus induces severe diseases on a wide range of plants and becomes an emerging threat to crop yields. However, the infectious clones of TSV remain to be developed for reverse genetics studies. Here, we obtained the full genome sequence of a TSV-CNB isolate and analyzed the phylogenetic characteristics. Subsequently, we developed the full-length infectious cDNA clones of TSV-CNB driven by 35 S promoter using yeast homologous recombination. Furthermore, the host range of TSV-CNB isolate was determined by Agrobact...
Source: Virology - February 19, 2024 Category: Virology Authors: Qi Liu Menglin Li Xuanyu Dong Chengxiao Zuo Zhangyao Nie Zongying Zhang Cheng-Gui Han Ying Wang Source Type: research
Development of full-length infectious cDNA clones and host range identification of an echinacea strain of tobacco streak virus
Virology. 2024 Feb 11;593:110013. doi: 10.1016/j.virol.2024.110013. Online ahead of print.ABSTRACTTobacco streak virus induces severe diseases on a wide range of plants and becomes an emerging threat to crop yields. However, the infectious clones of TSV remain to be developed for reverse genetics studies. Here, we obtained the full genome sequence of a TSV-CNB isolate and analyzed the phylogenetic characteristics. Subsequently, we developed the full-length infectious cDNA clones of TSV-CNB driven by 35 S promoter using yeast homologous recombination. Furthermore, the host range of TSV-CNB isolate was determined by Agrobact...
Source: Virology - February 19, 2024 Category: Virology Authors: Qi Liu Menglin Li Xuanyu Dong Chengxiao Zuo Zhangyao Nie Zongying Zhang Cheng-Gui Han Ying Wang Source Type: research
Development of full-length infectious cDNA clones and host range identification of an echinacea strain of tobacco streak virus
Virology. 2024 Feb 11;593:110013. doi: 10.1016/j.virol.2024.110013. Online ahead of print.ABSTRACTTobacco streak virus induces severe diseases on a wide range of plants and becomes an emerging threat to crop yields. However, the infectious clones of TSV remain to be developed for reverse genetics studies. Here, we obtained the full genome sequence of a TSV-CNB isolate and analyzed the phylogenetic characteristics. Subsequently, we developed the full-length infectious cDNA clones of TSV-CNB driven by 35 S promoter using yeast homologous recombination. Furthermore, the host range of TSV-CNB isolate was determined by Agrobact...
Source: Virology - February 19, 2024 Category: Virology Authors: Qi Liu Menglin Li Xuanyu Dong Chengxiao Zuo Zhangyao Nie Zongying Zhang Cheng-Gui Han Ying Wang Source Type: research
Exploring Echinacea purpurea ’s effect on wound healing in rats: FOXO1/MIP2 pathway modulation
AbstractThe extracellular matrix (ECM) is a crucial component in all human tissues. During injury, the ECM is damaged; wound healing phases as hemostasis, inflammation, proliferation, and remodeling result in ECM synthesized and return to its native state.Echinacea purpurea is one of the most important medicinal herbs and is well-known for its antioxidant, anti-inflammatory, and immunomodulatory activities. The main aim of this research was to investigate the anti-inflammatory and wound-healing properties ofEchinacea treatment in rats due to the need for more scientific evidence regarding the efficacy of this medicinal pla...
Source: Comparative Clinical Pathology - January 6, 2024 Category: Pathology Source Type: research
Echinacea purpurea extract intervention for counteracting neurochemical and behavioral changes induced by bifenthrin
In conclusion, the present study clearly indicated that EchEE can attenuate brai n dysfunction induced by pesticides exposure through preventing the oxidative stress. This may be attributed to its high antioxidant component. (Source: Metabolic Brain Disease)
Source: Metabolic Brain Disease - December 27, 2023 Category: Neurology Source Type: research
Echinacoside ameliorates doxorubicin ‑induced cardiac injury by regulating GPX4 inhibition‑induced ferroptosis
Exp Ther Med. 2023 Nov 23;27(1):29. doi: 10.3892/etm.2023.12317. eCollection 2024 Jan.ABSTRACTEchinacoside (ECH) is a compound derived from the natural herbs Cistanche and Echinacea, which has considerable protective effects on heart failure (HF). HF is characterized by myocardial damage and abnormal ferroptosis. Glutathione peroxidase 4 (GPX4) is an important regulator of ferroptosis, which plays a role in ferroptosis-related diseases. Despite this, the therapeutic mechanisms of ECH against HF remain unknown. Therefore, the aim of the present study was to investigate the cardioprotective effect and underlying mechanisms o...
Source: Experimental and Therapeutic Medicine - December 21, 2023 Category: General Medicine Authors: Yan Ma Xiaoli Yang Nianxin Jiang Cheng Lu Jiehan Zhang Shaowei Zhuang Source Type: research
