Rational and safe use of the top two botanical dietary supplements to enhance the immune system
Comb Chem High Throughput Screen. 2022 Feb 7. doi: 10.2174/1386207325666220207112937. Online ahead of print.ABSTRACTThe recent COVID-19 pandemic has sparked great interest in strengthening the immune system, especially by the consumption of widely available natural dietary supplements. Such popularity has suggested the sales of these products to grow significantly in the year 2021, especially for those who are unable or unwilling to receive COVID-19 vaccines. Among the many botanicals, Sambucus nigra L. (Elderberry) and Echinacea purpurea (L.) Moench (Echinacea) have especially shown great popularity. Various in vivo and i...
Source: Combinatorial Chemistry and High Throughput Screening - February 9, 2022 Category: Chemistry Authors: Hyunjin Kim Angela I Calder ón Source Type: research
Echinacoside exhibits antidepressant-like effects through AMPAR –Akt/ERK–mTOR pathway stimulation and BDNF expression in mice
Several natural products have been demonstrated to be effective in the treatment of depressive disorders. Echinacoside, a naturally occurring phenol extracted from Cistanche tubulosa, Echinacea angustifolia, and (Source: Chinese Medicine)
Source: Chinese Medicine - January 5, 2022 Category: Complementary Medicine Authors: Han-Wen Chuang, Tse-Yen Wang, Chih-Chia Huang and I-Hua Wei Tags: Research Source Type: research
COVID-19 and herbal practice: A United Kingdom practitioner survey
CONCLUSIONS: Herbal practitioners need to build on current collaborations, research and experience to develop consistent approaches to support people with mild-moderate COVID-19 symptoms. More systematic exploration of herbal medicine practice during and as a consequence of the pandemic is needed.WHAT IS ALREADY KNOWN ABOUT THE TOPIC: • The COVID-19 pandemic has had a large impact on all types of healthcare• The impact on herbal medicine practice is unclear.WHAT THIS PAPER ADDS: • The COVID-19 pandemic has substantially affected UK herbal medicine practice• A wide range of medicinal plants are currently used by her...
Source: Adv Data - December 10, 2021 Category: Epidemiology Authors: Rachael Frost Sukvinder Kaur Bhamra Barbara Pendry Michael Heinrich Source Type: research
COVID-19 and herbal practice: A United Kingdom practitioner survey
CONCLUSIONS: Herbal practitioners need to build on current collaborations, research and experience to develop consistent approaches to support people with mild-moderate COVID-19 symptoms. More systematic exploration of herbal medicine practice during and as a consequence of the pandemic is needed.WHAT IS ALREADY KNOWN ABOUT THE TOPIC: • The COVID-19 pandemic has had a large impact on all types of healthcare• The impact on herbal medicine practice is unclear.WHAT THIS PAPER ADDS: • The COVID-19 pandemic has substantially affected UK herbal medicine practice• A wide range of medicinal plants are currently used by her...
Source: Adv Data - December 10, 2021 Category: Epidemiology Authors: Rachael Frost Sukvinder Kaur Bhamra Barbara Pendry Michael Heinrich Source Type: research
COVID-19 and herbal practice: A United Kingdom practitioner survey
CONCLUSIONS: Herbal practitioners need to build on current collaborations, research and experience to develop consistent approaches to support people with mild-moderate COVID-19 symptoms. More systematic exploration of herbal medicine practice during and as a consequence of the pandemic is needed.WHAT IS ALREADY KNOWN ABOUT THE TOPIC: • The COVID-19 pandemic has had a large impact on all types of healthcare• The impact on herbal medicine practice is unclear.WHAT THIS PAPER ADDS: • The COVID-19 pandemic has substantially affected UK herbal medicine practice• A wide range of medicinal plants are currently used by her...
Source: Adv Data - December 10, 2021 Category: Epidemiology Authors: Rachael Frost Sukvinder Kaur Bhamra Barbara Pendry Michael Heinrich Source Type: research
Echinacea purpurea suppresses the cell survival and metastasis of hepatocellular carcinoma through regulating the PI3K/Akt pathway
This study showed that Ep ameliorates HCC-induced tumor cell survival and migration in mice via the regulation of the PI3K/Akt pathway. Thus, Ep might be a potential new strategy to prevent the growth and metastasis of HCC.PMID:34743003 | DOI:10.1016/j.biocel.2021.106115 (Source: The International Journal of Biochemistry and Cell Biology)
Source: The International Journal of Biochemistry and Cell Biology - November 7, 2021 Category: Biochemistry Authors: Wenqian Xu Bin Hu Yuliang Cheng Yahui Guo Weirong Yao He Qian Source Type: research
Echinacea purpurea suppresses the cell survival and metastasis of hepatocellular carcinoma through regulating the PI3K/Akt pathway
This study showed that Ep ameliorates HCC-induced tumor cell survival and migration in mice via the regulation of the PI3K/Akt pathway. Thus, Ep might be a potential new strategy to prevent the growth and metastasis of HCC.PMID:34743003 | DOI:10.1016/j.biocel.2021.106115 (Source: The International Journal of Biochemistry and Cell Biology)
Source: The International Journal of Biochemistry and Cell Biology - November 7, 2021 Category: Biochemistry Authors: Wenqian Xu Bin Hu Yuliang Cheng Yahui Guo Weirong Yao He Qian Source Type: research
Dietary supplements, cytochrome metabolism, and pharmacogenetic considerations
ConclusionCYP P450 activity is an important consideration for any patient but becomes increasingly critical if patients have certain CYP P450 phenotypes that impact metabolism. These popular supplements have the potential for changes in supplement exposure, and adverse effects based on pharmacogenetic profiles. Furthermore, these sites of metabolism are shared with many medications, setting the stage for possibly more profound interactions between medications and supplements. This paper highlights the mechanisms in which dietary supplements may constitute a risk for patients with certain CYP P450 phenotypes. Further resear...
Source: Irish Journal of Medical Science - November 4, 2021 Category: General Medicine Source Type: research
Echinacea purpurea Extract Enhances Natural Killer Cell Activity In Vivo by Upregulating MHC II and Th1-type CD4+ T Cell Responses
Journal of Medicinal Food,Volume 24, Issue 10, Page 1039-1049, October 2021. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - October 15, 2021 Category: Nutrition Authors: Soo-Jeung Park Minhee Lee Dakyung Kim Dong Hwan Oh Kodimule Shyam Prasad Sangwon Eun Jeongmin Lee Source Type: research
Food and immunity: a pragmatic approach to mitigate corona viruses attack
Muhammad Farhan Jahangir Chughtai, Saira Tanweer, Samreen Ahsan, Tariq Mehmood, Atif Liaqat, Adnan Khaliq, Tahir Zahoor, Muhammad Nadeem, Nazia Khalid, Saadia Zainab, Syed Junaid-ur-Rahman
Nutrition & Food Science, Vol. ahead-of-print, No. ahead-of-print, pp.-
Corona viruses have spiked structure and enveloped glycoproteins in their structure, along with specific proteins in membranes. The mode of action of COVID-19 consists of three phases, i.e. viral replication, immune hyperactivity and pulmonary destruction. However, angiotensin-converting enzyme is an essential receptor that causes COV...
Source: Nutrition and Food Science - October 11, 2021 Category: Nutrition Authors: Muhammad Farhan Jahangir Chughtai
Saira Tanweer
Samreen Ahsan
Tariq Mehmood
Atif Liaqat
Adnan Khaliq
Tahir Zahoor
Muhammad Nadeem
Nazia Khalid
Saadia Zainab
Syed Junaid-ur-Rahman Source Type: research
Herb-drug interactions in neuropsychiatric pharmacotherapy - a review of clinically relevant findings
This study reviewed the relevant literature and identified 13 commonly used herbal products - celery, echinacea, ginkgo, ginseng, hydroxycut, kava, kratom, moringa, piperine, rhodiola, St John's wort, terminalia/commiphora ayurvedic mixture and valerian - which have shown clinically relevant interactions with prescription drugs used in the management of neuropsychiatric disorders. The clinical focus is aimed to provide easily accessible information that will be of interest to clinicians, researchers, and the drug-consuming public.PMID:34370637 | DOI:10.2174/1570159X19666210809100357 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - August 9, 2021 Category: Drugs & Pharmacology Authors: Tram T Le Sarah R McGrath Pius S Fasinu Source Type: research
Herb-drug interactions in neuropsychiatric pharmacotherapy - a review of clinically relevant findings
This study reviewed the relevant literature and identified 13 commonly used herbal products - celery, echinacea, ginkgo, ginseng, hydroxycut, kava, kratom, moringa, piperine, rhodiola, St John's wort, terminalia/commiphora ayurvedic mixture and valerian - which have shown clinically relevant interactions with prescription drugs used in the management of neuropsychiatric disorders. The clinical focus is aimed to provide easily accessible information that will be of interest to clinicians, researchers, and the drug-consuming public.PMID:34370637 | DOI:10.2174/1570159X19666210809100357 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - August 9, 2021 Category: Drugs & Pharmacology Authors: Tram T Le Sarah R McGrath Pius S Fasinu Source Type: research
Herb-drug interactions in neuropsychiatric pharmacotherapy - a review of clinically relevant findings
This study reviewed the relevant literature and identified 13 commonly used herbal products - celery, echinacea, ginkgo, ginseng, hydroxycut, kava, kratom, moringa, piperine, rhodiola, St John's wort, terminalia/commiphora ayurvedic mixture and valerian - which have shown clinically relevant interactions with prescription drugs used in the management of neuropsychiatric disorders. The clinical focus is aimed to provide easily accessible information that will be of interest to clinicians, researchers, and the drug-consuming public.PMID:34370637 | DOI:10.2174/1570159X19666210809100357 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - August 9, 2021 Category: Drugs & Pharmacology Authors: Tram T Le Sarah R McGrath Pius S Fasinu Source Type: research
Herb-drug interactions in neuropsychiatric pharmacotherapy - a review of clinically relevant findings
This study reviewed the relevant literature and identified 13 commonly used herbal products - celery, echinacea, ginkgo, ginseng, hydroxycut, kava, kratom, moringa, piperine, rhodiola, St John's wort, terminalia/commiphora ayurvedic mixture and valerian - which have shown clinically relevant interactions with prescription drugs used in the management of neuropsychiatric disorders. The clinical focus is aimed to provide easily accessible information that will be of interest to clinicians, researchers, and the drug-consuming public.PMID:34370637 | DOI:10.2174/1570159X19666210809100357 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - August 9, 2021 Category: Drugs & Pharmacology Authors: Tram T Le Sarah R McGrath Pius S Fasinu Source Type: research
Herb-drug interactions in neuropsychiatric pharmacotherapy - a review of clinically relevant findings
This study reviewed the relevant literature and identified 13 commonly used herbal products - celery, echinacea, ginkgo, ginseng, hydroxycut, kava, kratom, moringa, piperine, rhodiola, St John's wort, terminalia/commiphora ayurvedic mixture and valerian - which have shown clinically relevant interactions with prescription drugs used in the management of neuropsychiatric disorders. The clinical focus is aimed to provide easily accessible information that will be of interest to clinicians, researchers, and the drug-consuming public.PMID:34370637 | DOI:10.2174/1570159X19666210809100357 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - August 9, 2021 Category: Drugs & Pharmacology Authors: Tram T Le Sarah R McGrath Pius S Fasinu Source Type: research
