Communication to promote and support physical distancing for COVID-19 prevention and control
CONCLUSIONS: Implications for practice Evidence highlights the critical role of communication throughout a public health emergency. Like any intervention, communication can be done well or poorly, but the consequences of poor communication during a pandemic may mean the difference between life and death. The approaches to effective communication identified in this review can be used by policymakers and decision-makers, working closely with communication teams, to plan, implement and adjust public communications over the course of a public health emergency like the COVID-19 pandemic. Implications for research Despite massiv...
Source: Cochrane Database of Systematic Reviews - October 9, 2023 Category: General Medicine Authors: Rebecca E Ryan Charlotte Silke Anne Parkhill Ariane Virgona Bronwen Merner Shauna Hurley Louisa Walsh Caroline de Moel-Mandel Lina Schonfeld Adrian Gk Edwards Jessica Kaufman Alison Cooper Rachel Kar Yee Chung Karla Solo Margaret Hellard Gian Luca Di Tann Source Type: research
Communication to promote and support physical distancing for COVID-19 prevention and control
CONCLUSIONS: Implications for practice Evidence highlights the critical role of communication throughout a public health emergency. Like any intervention, communication can be done well or poorly, but the consequences of poor communication during a pandemic may mean the difference between life and death. The approaches to effective communication identified in this review can be used by policymakers and decision-makers, working closely with communication teams, to plan, implement and adjust public communications over the course of a public health emergency like the COVID-19 pandemic. Implications for research Despite massiv...
Source: Cochrane Database of Systematic Reviews - October 9, 2023 Category: General Medicine Authors: Rebecca E Ryan Charlotte Silke Anne Parkhill Ariane Virgona Bronwen Merner Shauna Hurley Louisa Walsh Caroline de Moel-Mandel Lina Schonfeld Adrian Gk Edwards Jessica Kaufman Alison Cooper Rachel Kar Yee Chung Karla Solo Margaret Hellard Gian Luca Di Tann Source Type: research
Adaptation of an rVSV Ebola vaccine purification process for rapid development of a viral vaccine candidate for SARS-CoV-2
This article is protected by copyright. All rights reserved.PMID:37766672 | DOI:10.1002/biot.202300041 (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 28, 2023 Category: Biotechnology Authors: Laura E Kuczynski James R Shallow Matthew P Watson Michael L Homsy Thomas Svab Ashley Gruber Richard R Rustandi Jianfang Hu Michael A Winters Source Type: research
Anthony Fauci on becoming the ‘devil’ and a warning for his successor
Last Wednesday afternoon, Anthony Fauci, one of the world’s most famous scientists, answered the door of his Washington, D.C., house in jeans and a T-shirt, apologizing for the boxes in his living room. Although he retired in December 2022 from directing the National Institute of Allergy and Infectious Diseases (NIAID), he has just recently finished deciding what should go to archives at the National Institutes of Health (NIH) and what to keep from the abundant memorabilia he had collected from his
38 years in that job
.
An immunologist by training, Fauci spent much of his career overseeing the world’s ...
Source: Science of Aging Knowledge Environment - September 25, 2023 Category: Geriatrics Source Type: research
Immunological correlates of protection afforded by PHV02 live, attenuated recombinant vesicular stomatitis virus vector vaccine against Nipah virus disease
Discussion and conclusionIt was concluded that PHV02 vaccine elicited a rapid onset of protection and that any detectable level of neutralizing antibody was a functional immune correlate of survival. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - September 4, 2023 Category: Allergy & Immunology Source Type: research
Factors that impact on recruitment to vaccine trials in the context of a pandemic or epidemic: a qualitative evidence synthesis
CONCLUSIONS: This review identifies many of the factors that influence a person's decision to take part in a vaccine trial, and these reflect findings from reviews that examine trials more broadly. However, we also recognise some factors that become more important in connection with a vaccine trial in the context of a pandemic or epidemic. These factors include the potential stigma of taking part, the possible adverse effects of a vaccine, the added motivation for helping society, the role of community leaders in trial dissemination, and the level of trust placed in governments and companies developing vaccines. These spec...
Source: Cochrane Database of Systematic Reviews - September 1, 2023 Category: General Medicine Authors: Pauline Meskell Linda M Biesty Maura Dowling Kevin Roche Elaine Meehan Claire Glenton Declan Devane Sasha Shepperd Andrew Booth Rebecca Cox Xin Hui S Chan Catherine Houghton Source Type: research
Factors that impact on recruitment to vaccine trials in the context of a pandemic or epidemic: a qualitative evidence synthesis
CONCLUSIONS: This review identifies many of the factors that influence a person's decision to take part in a vaccine trial, and these reflect findings from reviews that examine trials more broadly. However, we also recognise some factors that become more important in connection with a vaccine trial in the context of a pandemic or epidemic. These factors include the potential stigma of taking part, the possible adverse effects of a vaccine, the added motivation for helping society, the role of community leaders in trial dissemination, and the level of trust placed in governments and companies developing vaccines. These spec...
Source: Cochrane Database of Systematic Reviews - September 1, 2023 Category: General Medicine Authors: Pauline Meskell Linda M Biesty Maura Dowling Kevin Roche Elaine Meehan Claire Glenton Declan Devane Sasha Shepperd Andrew Booth Rebecca Cox Xin Hui S Chan Catherine Houghton Source Type: research
Factors that impact on recruitment to vaccine trials in the context of a pandemic or epidemic: a qualitative evidence synthesis
CONCLUSIONS: This review identifies many of the factors that influence a person's decision to take part in a vaccine trial, and these reflect findings from reviews that examine trials more broadly. However, we also recognise some factors that become more important in connection with a vaccine trial in the context of a pandemic or epidemic. These factors include the potential stigma of taking part, the possible adverse effects of a vaccine, the added motivation for helping society, the role of community leaders in trial dissemination, and the level of trust placed in governments and companies developing vaccines. These spec...
Source: Cochrane Database of Systematic Reviews - September 1, 2023 Category: General Medicine Authors: Pauline Meskell Linda M Biesty Maura Dowling Kevin Roche Elaine Meehan Claire Glenton Declan Devane Sasha Shepperd Andrew Booth Rebecca Cox Xin Hui S Chan Catherine Houghton Source Type: research
Factors that impact on recruitment to vaccine trials in the context of a pandemic or epidemic: a qualitative evidence synthesis
CONCLUSIONS: This review identifies many of the factors that influence a person's decision to take part in a vaccine trial, and these reflect findings from reviews that examine trials more broadly. However, we also recognise some factors that become more important in connection with a vaccine trial in the context of a pandemic or epidemic. These factors include the potential stigma of taking part, the possible adverse effects of a vaccine, the added motivation for helping society, the role of community leaders in trial dissemination, and the level of trust placed in governments and companies developing vaccines. These spec...
Source: Cochrane Database of Systematic Reviews - September 1, 2023 Category: General Medicine Authors: Pauline Meskell Linda M Biesty Maura Dowling Kevin Roche Elaine Meehan Claire Glenton Declan Devane Sasha Shepperd Andrew Booth Rebecca Cox Xin Hui S Chan Catherine Houghton Source Type: research
Persistence of immunological memory as a potential correlate of long-term, vaccine-induced protection against Ebola virus disease in humans
DiscussionHumans infected with Ebola virus may benefit from the anamnestic response to prevent disease progression, as the incubation time is longer and progression of Ebola virus disease is slower as compared to non-human primates. Therefore, the persistence of vaccine-induced immune memory could be considered as a potential correlate of long-term protection against Ebola virus disease in humans, without the need for a booster. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - September 1, 2023 Category: Allergy & Immunology Source Type: research
Global dynamics of a compartmental model to assess the effect of transmission from deceased
We present a compartmental model for the spread of a disease with an imperfect vaccine available, also considering transmission from deceased infected in general. The global dynamics of the system are completely described by constructing appropriate Lyapunov functions. To support our analytical results, we perform numerical simulations to assess the importance of transmission from the deceased, considering the data collected from three infectious diseases, Ebola virus disease, COVID-19, and Nipah fever.PMID:37619887 | DOI:10.1016/j.mbs.2023.109059 (Source: Mathematical Biosciences)
Source: Mathematical Biosciences - August 24, 2023 Category: Statistics Authors: Saumen Barua Attila D énes Source Type: research
Global dynamics of a compartmental model to assess the effect of transmission from deceased
We present a compartmental model for the spread of a disease with an imperfect vaccine available, also considering transmission from deceased infected in general. The global dynamics of the system are completely described by constructing appropriate Lyapunov functions. To support our analytical results, we perform numerical simulations to assess the importance of transmission from the deceased, considering the data collected from three infectious diseases, Ebola virus disease, COVID-19, and Nipah fever.PMID:37619887 | DOI:10.1016/j.mbs.2023.109059 (Source: Mathematical Biosciences)
Source: Mathematical Biosciences - August 24, 2023 Category: Statistics Authors: Saumen Barua Attila D énes Source Type: research
Global dynamics of a compartmental model to assess the effect of transmission from deceased
We present a compartmental model for the spread of a disease with an imperfect vaccine available, also considering transmission from deceased infected in general. The global dynamics of the system are completely described by constructing appropriate Lyapunov functions. To support our analytical results, we perform numerical simulations to assess the importance of transmission from the deceased, considering the data collected from three infectious diseases, Ebola virus disease, COVID-19, and Nipah fever.PMID:37619887 | DOI:10.1016/j.mbs.2023.109059 (Source: Mathematical Biosciences)
Source: Mathematical Biosciences - August 24, 2023 Category: Statistics Authors: Saumen Barua Attila D énes Source Type: research
Perspectives on Advancing Countermeasures for Filovirus Disease: Report from a Multi-Sector Meeting
Discussion participants recommended a follow-up meeting be held in Africa with national public health and research agencies from at-risk countries to establish such a consortium.PMID:37596837 | DOI:10.1093/infdis/jiad354 (Source: Cancer Control)
Source: Cancer Control - August 19, 2023 Category: Cancer & Oncology Authors: Armand Sprecher Robert Cross Andrea Marzi Karen A Martins Daniel Wolfe Joel M Montgomery Christina F Spiropoulou Tomas Cihlar Steve Ahuka-Mundeke Tara Nyhuis Carrie Teicher Ian Crozier Jim Strong Gary Kobinger Courtney Woolsey Thomas W Geisbert Heinz Feld Source Type: research
SARS-CoV-2 variants, its recombinants and epigenomic exploitation of host defenses
Biochim Biophys Acta Mol Basis Dis. 2023 Aug 5:166836. doi: 10.1016/j.bbadis.2023.166836. Online ahead of print.ABSTRACTSince 2003, we have seen the emergence of novel viruses, such as SARS-CoV-1, MERS, ZIKA, swine flu virus H1N1, Marburg, Monkeypox, Ebola, and SARS-CoV-2, but none of them gained pandemic proportions similar to SARS-CoV-2. This could be attributed to unique viral traits, allowing its rapid global dissemination following its emergence in October 2019 in Wuhan, China, which appears to be primarily driven by the emergence of highly transmissible and virulent variants that also associate, in some cases, with s...
Source: Biochimica et Biophysica Acta - August 7, 2023 Category: Biochemistry Authors: Nitin K Saksena Srinivas Bonam Reddy Monica Miranda-Saksena Thyago H S Cardoso Edson M A Silva Juliana C Fereira Wael M Rabeh Source Type: research
