Sudan virus disease - A quick review
J Formos Med Assoc. 2023 Jun 22:S0929-6646(23)00229-2. doi: 10.1016/j.jfma.2023.06.001. Online ahead of print.ABSTRACTThe recent Sudan virus disease (SVD) outbreak in Uganda is a reminder of threat from Filovirus diseases. Unlike Ebola virus disease, no effective antiviral and vaccine is available for SVD. The outbreak was declared over after 115 days, with 142 confirmed cases and case fatality rate of 39%, before any dose of candidate vaccine could be used on contacts. We provide a quick review of up-to-date information on the Uganda outbreak, summary of previous outbreaks, and detail the existing SVD treatment and vaccin...
Source: J Formos Med Assoc - June 24, 2023 Category: General Medicine Authors: Tsung-Pei Tsou Source Type: research
Sudan virus disease - A quick review
J Formos Med Assoc. 2023 Jun 22:S0929-6646(23)00229-2. doi: 10.1016/j.jfma.2023.06.001. Online ahead of print.ABSTRACTThe recent Sudan virus disease (SVD) outbreak in Uganda is a reminder of threat from Filovirus diseases. Unlike Ebola virus disease, no effective antiviral and vaccine is available for SVD. The outbreak was declared over after 115 days, with 142 confirmed cases and case fatality rate of 39%, before any dose of candidate vaccine could be used on contacts. We provide a quick review of up-to-date information on the Uganda outbreak, summary of previous outbreaks, and detail the existing SVD treatment and vaccin...
Source: J Formos Med Assoc - June 24, 2023 Category: General Medicine Authors: Tsung-Pei Tsou Source Type: research
New U.S. lab will work with deadly animal pathogens —in the middle of farm country
Virologist Robert Cross’s lab is equipped to handle some of the world’s most dangerous viruses. At the Galveston National Laboratory he has worked with guinea pigs infected with Ebola virus and macaques carrying Lassa fever. What it can’t accommodate are pigs, which are common carriers of the deadly Nipah virus. “We’re not really geared to handle large animals,” says Cross, who wears a pressurized biosafety suit for his studies. “You can’t just pick them up when you’re wearing these space suits.”
That’s one reason why Cross is welcoming tomorrow’s
ceremonial opening
of a massive new ...
Source: Science of Aging Knowledge Environment - May 23, 2023 Category: Geriatrics Source Type: research
News at a glance: A respiratory disease vaccine, observing intensifying cyclones, and shaking a tall wooden building
ENGINEERING
Tall wood building is shaken, but not scathed
A 10-story wooden building survived two severe, simulated earthquakes intact this week as scientists sought to show that wood can rival steel and concrete to safely support tall buildings. The structure is the tallest ever tested at the University of California, San Diego’s earthquake simulator. As part of a project funded by the U.S. National Science Foundation, the machine subjected the building to the equivalent of the 1994 6.7 magnitude Northridge, California, quake. A few minutes later it re-created a 1999 7.7 magnitude temblor that str...
Source: Science of Aging Knowledge Environment - May 11, 2023 Category: Geriatrics Source Type: research
Effects of public health emergencies of international concern on disease control: a systematic review
CONCLUSIONS: Socioeconomic inequity is a determinant of the effects of public health emergencies of international concern within affected populations. The diversion of resources and attention from health authorities disproportionately affects vulnerable populations and can lead, over time, to a weakening of health systems. The analysis of the effects of public health emergencies is important for the development of new protocols that can better respond to future crises.PMID:37089787 | PMC:PMC10120386 | DOI:10.26633/RPSP.2023.74 (Source: Pan American Journal of Public Health)
Source: Pan American Journal of Public Health - April 24, 2023 Category: International Medicine & Public Health Authors: Giovanna Rotondo de Ara újo Pedro A S V de Castro Isabela R Ávila Juliana Maria T Bezerra David S Barbosa Source Type: research
Immune correlates of protection for SARS-CoV-2, Ebola and Nipah virus infection
Correlates of protection (CoP) are biological parameters that predict a certain level of protection against an infectious disease. Well-established correlates of protection facilitate the development and licensing of vaccines by assessing protective efficacy without the need to expose clinical trial participants to the infectious agent against which the vaccine aims to protect. Despite the fact that viruses have many features in common, correlates of protection can vary considerably amongst the same virus family and even amongst a same virus depending on the infection phase that is under consideration. Moreover, the comple...
Source: Frontiers in Immunology - April 17, 2023 Category: Allergy & Immunology Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
