Analysis of the patients with nonvariceal upper gastrointestinal bleeding and comparison of Rockall and Glasgow-Blatchford scores
ConclusionNonvariceal UGB patients with a Rockall score greater than 6 should undergo aggressive endoscopic treatment and inpatient care. (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - December 26, 2022 Category: Gastroenterology Source Type: research
Necitumumab plus gemcitabine and cisplatin in previously treated lung squamous cell carcinoma
Conclusion: N + GC displayed good efficacy in the second line or later treatment among patients with LSCC. This study suggested that N + GC is a useful option even after second-line treatment of advanced-stage or recurrent LSCC, although the management of adverse events is essential. (Source: Investigational New Drugs)
Source: Investigational New Drugs - November 4, 2022 Category: Drugs & Pharmacology Source Type: research
Long-term safety and effectiveness of vonoprazan for prevention of gastric and duodenal ulcer recurrence in patients on nonsteroidal anti-inflammatory drugs in Japan: a 12-month post-marketing surveillance study
CONCLUSIONS: No new safety concerns were reported for vonoprazan for prevention of secondary ulcer or bleeding in patients receiving long-term NSAIDs. Vonoprazan was effective for preventing NSAID-related peptic ulcer recurrence in this real-world study.TRIAL REGISTRATION: ClinicalTrials.gov: NCT03214198; Japan Pharmaceutical Information Center Clinical Trials Information: JapicCTI-163436.PMID:36264125 | DOI:10.1080/14740338.2023.2136163 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - October 20, 2022 Category: Drugs & Pharmacology Authors: Takashi Kawai Chihiro Suzuki Youichirou Honda Jovelle L Fernandez Source Type: research
Cancers, Vol. 14, Pages 4905: The Association between Peptic Ulcer Disease and Gastric Cancer: Results from the Stomach Cancer Pooling (StoP) Project Consortium
Conclusions. In the pooled analysis of 11 case–control studies in a large consortium (i.e., the Stomach cancer Pooling (StoP) consortium), we found a positive association between GU and risk of GC and no association between DU and GC risk. (Source: Cancers)
Source: Cancers - October 7, 2022 Category: Cancer & Oncology Authors: Pedram Paragomi Bashir Dabo Claudio Pelucchi Rossella Bonzi Abdulaziz T. Bako Nabila Muhammad Sanusi Quan H. Nguyen Zuo-Feng Zhang Domenico Palli Monica Ferraroni Khanh Truong Vu Guo-Pei Yu Federica Turati David Zaridze Dmitry Maximovitch Jinfu Hu Lina Mu Tags: Article Source Type: research
Endoscopy in Infants With Gastrointestinal Bleeding Has Limited Diagnostic or Therapeutic Benefit
Objectives:
Pediatric gastroenterologists are often consulted to perform diagnostic and therapeutic endoscopy in infants with gastrointestinal bleeding (GIB). The value of endoscopy and risk of complications in this population are not well characterized. We aimed to describe findings and outcomes of infants with GIB who undergo endoscopy.
Methods:
Retrospective, single-center, cohort study of hospitalized infants ≤12 months who underwent esophagogastroduodenoscopy (EGD) and/or colonoscopy/flexible sigmoidoscopy (COL) for GIB. Current procedural technology codes, international classification of diseases codes, ...
Source: Journal of Pediatric Gastroenterology and Nutrition - September 23, 2022 Category: Gastroenterology Tags: Original Article: Endoscopy and Procedures Source Type: research
In vitro and in vivo evaluation of a novel wired transmission magnetically controlled capsule endoscopy system for upper gastrointestinal examination
ConclusionsThe novel WT-MCCE system performed well in evaluating upper gastrointestinal landmarks and lesions in two in vitro models, and showed good performance in a canine model. WT-MCCE may be potentially useful for diagnosis of esophageal and gastric diseases.Graphical abstract (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - September 16, 2022 Category: Surgery Source Type: research
An unusual case of duodenal ulcer
Asian J Surg. 2022 Aug 30:S1015-9584(22)01113-7. doi: 10.1016/j.asjsur.2022.08.001. Online ahead of print.NO ABSTRACTPMID:36055888 | DOI:10.1016/j.asjsur.2022.08.001 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - September 2, 2022 Category: Surgery Authors: Xiaohua Ye Yuanyuan Ding Ting Yang Lei Wang Source Type: research
An unusual case of duodenal ulcer
Asian J Surg. 2022 Aug 30:S1015-9584(22)01113-7. doi: 10.1016/j.asjsur.2022.08.001. Online ahead of print.NO ABSTRACTPMID:36055888 | DOI:10.1016/j.asjsur.2022.08.001 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - September 2, 2022 Category: Surgery Authors: Xiaohua Ye Yuanyuan Ding Ting Yang Lei Wang Source Type: research
Perforated duodenal ulcer in the third trimester of pregnancy, with survival of both the mother and neonate, in Ethiopia: a case report
ConclusionsPerforated PUD in pregnancy is a rare occurrence, which may account for the delay in diagnosis and management. Obstetricians should keep a high index of suspicion when a pregnant woman presents with acute abdomen. Care provided by obstetricians should be coupled with care provided by other disciplinary teams, in order to reduce maternal and fetal morbidity and mortality. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - August 29, 2022 Category: General Medicine Source Type: research
Laparoscopic distal gastric and D1 resection for large perforated duodenal bulb peptic ulcer, with intracorporeal antecolic gastrojejunal anastomosis
ConclusionsAlthough the incidence of peptic ulcer disease is decreasing, it appears that the incidence of complications is rising. Laparoscopic approach, especially when performed by laparoscopic surgery experts, could be a treatment option for difficult duodenal ulcer perforations with less pain, shorter hospital stay and reduced morbidity. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - August 25, 2022 Category: Surgery Source Type: research
IJERPH, Vol. 19, Pages 10253: Causes of Hospitalization among End-Stage Kidney Disease Cohort before and after Hemodialysis
This study recruited 592 patients with ESKD who received hemodialysis at any period between January 2005 and November 2017 and had been assigned the International Classification of Diseases Ninth Revision Clinical Modification (ICD-9-CM) code for ESKD. The patients’ demographic data and hospitalization status one year before and two years after they received hemodialysis were analyzed. A McNemar test was conducted to analyze the diagnostic changes from before to after hemodialysis in patients with ESKD. The study’s sample of patients with ESKD comprised more women (51.86%) than men and had an av...
Source: International Journal of Environmental Research and Public Health - August 18, 2022 Category: Environmental Health Authors: Hsiu-Lan Li Pei-Hui Tai Yi-Ting Hwang Shih-Wei Lin Li-Ching Lan Tags: Article Source Type: research
Splenic Abscess due to a Perforated Duodenal Ulcer Successfully Treated with Endoscopic Ultrasound-Guided Transgastric Drainage
Splenic abscesses are rare, with a reported prevalence of 0.14 –0.7% in autopsy studies. The treatment options for splenic abscesses include intravenous antimicrobial therapy, percutaneous drainage, and splenectomy. Although the dissemination of endoscopic ultrasound (EUS) intervention techniques has made it possible to perform puncture and drainage via the t ransgastrointestinal route for intra-abdominal abscesses where the percutaneous route has been difficult, there have been few reports of EUS-guided drainage of splenic abscesses. A case of a splenic abscess associated with a perforated duodenal ulcer that was succes...
Source: Case Reports in Gastroenterology - August 16, 2022 Category: Gastroenterology Source Type: research
Risk factors for leak after omentopexy for duodenal ulcer perforations
ConclusionLeak after omentopexy carries a high morbidity and mortality. Identification of risk factors may help in optimizing patients at risk and reduce the incidence of leak and its sequelae.Trial registration numberCTRI/2020/03/023798. (Source: European Journal of Trauma and Emergency Surgery)
Source: European Journal of Trauma and Emergency Surgery - July 23, 2022 Category: Emergency Medicine Source Type: research
Secondary Choledocholithiasis in Obstructive Jaundice Patient due to Choledochoduodenal-fistula Stricture
Acta Med Indones. 2022 Apr;54(2):283-287.ABSTRACTCholedochoduodenal fistula (CDF) is a rare condition marked by an abnormal connection between the biliary duct and duodenum. The common etiology of secondary CDF are cholecystolithiasis, tumor, and duodenal ulcer. CDF may also caused by prior inflammatory condition or as a complication of radiation therapy. Management for this case is based on the patient condition. Herein we aimed to present a case of secondary choledocholithiasis due to stricture in the CDF which presented with cholangitis treated by self-expanding metal stent (SEMS) for biliary drainage. Patient admitted ...
Source: Acta medica Indonesiana - July 12, 2022 Category: Internal Medicine Authors: Muhammad Begawan Bestari Eka Surya Nugraha Siti Aminah Abdurachman Source Type: research
