Pulmonary Fibrosis Caused by Severe COVID-19 Infection: Discharge May Not Be The End of Treatment
Acta Med Indones. 2021 Apr;53(2):141-142.ABSTRACTSince December 2019, COVID-19 caused by SARS-CoV-2 infection has been spread rapidly in the world. Beside acute respiratory distress syndrome found in acute phase of infection, there is also pulmonary fibrosis as a chronic complication due to COVID-19. With the global pandemic of COVID-19, more and more autopsy and puncture histopathological results have been published.Until now there is no specific therapy to handle post-inflammatory pulmonary fibrosis due to COVID-19 infection. Several studies are ongoing to determine an effective treatment for this chronic complication. W...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Cleopas Martin Rumende Source Type: research

Validation of the Indonesian Version of the Asian Diabetes Quality of Life Questionnaire
CONCLUSION: Indonesian version of Asian DQOL is a valid and reliable tool to measure quality of life of type 2 diabetes mellitus patients.PMID:34251341 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Hikmat Permana Michelle Vincentia Liem Nanny N M Soetedjo Source Type: research

Association of BsmI Polymorphisms in the Vitamin D Receptor Gene Among Indonesian Population with Diabetic Kidney Disease
CONCLUSION: the profile of BsmI polymorphisms in the vitamin D receptor gene in the Indonesian population were genotypes Bb (89.2%) and bb (10.8%). There was no association between BsmI polymorphisms in the vitamin D receptor gene and DKD. Duration of DM more than five years influenced the association between those variables.PMID:34251342 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Pringgodigdo Nugroho Aida Lydia Suhardjono Suhardjono Kuntjoro Harimurti Source Type: research

Frequency of Acute Kidney Injury in Patient Receiving Piperacillin - Tazobactam: A Hospital-based Study from Qatar
Acta Med Indones. 2021 Apr;53(2):156-163.ABSTRACTBACKGROUND: several studies have been reported piperacillin-tazobactam (TAZ / PIPC)-associated AKI with various frequencies. The aim of this study was to determine the frequency of TAZ/PIPC- associated AKI among our patients and to identify the risk factors for this clinical entity.METHODS: this retrospective cross-sectional study was conducted at Hamad General Hospital; it involved adult patients who were admitted from January 2017 to December 2017.RESULTS: we involved 917 patients, of whom 635 (69.25%) were males and 282 (30.75%) were females. The mean age of the patients ...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Fahmi Yousef Khan Ahmed M Abdalhadi Rashid Kazman Dalal Sideeg Mudawi Khalid Shariff Aasir Suliman Hammad Shabir Chaudhry Rohit Sharma Ahmed Elballat Abdel-Monem Badawi Yousif Awni Alshurafa Fateen Ata Source Type: research

The Correlation Between HbA1c and Neuropathy Disability Score in Type 2 Diabetes
CONCLUSION: there is a relationship between HbA1c level and the severity of diabetic neuropathy in Type 2 DM.PMID:34251344 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Ilsa Hunaifi I Gusti Ngurah Ommy Agustriadi I Gede Yasa Asmara Catharina Budyono Source Type: research

The Risk Factors of Multidrug-Resistant Organisms in Hospitalized Patients with Community-Acquired Pneumonia in Dr. Soetomo Hospital Surabaya, Indonesia
This study aimed to analyze MDRO as the etiology of hospitalized patients with CAP along with its risk factors in Dr. Soetomo Hospital as one of the top referral hospitals in east Indonesia.METHODS: this retrospective cohort study was conducted from January 2016 to December 2018. Data were collected from patients' medical records. Automatic Rapid Diagnosis (Phoenix TM) was used as a standard method for culture and susceptibility test. Various risk factors were analyzed for MDRO infection.RESULTS: five most common pathogens in hospitalized patients with CAP were Acinetobacter baumannii 244/1364 (17.9%), Klebsiella pneumonia...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Soedarsono Soedarsono Putu Dyah Widyaningsih Ni Made Mertaniasih Source Type: research

Factors Associated with Arterial Stiffness in Chronic Hemodialysis Patients in Jakarta: The Role of Hemodialysis Frequency and Pentraxin 3
CONCLUSION: predialysis PTX3 levels above 2.3 ng/ml were associated with arterial stiffness. There was no difference in arterial stiffness between patients with twice- and thrice-weekly hemodialysis.PMID:34251346 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Elizabeth Yasmine Wardoyo Ginova Nainggolan Ni Made Hustrini Siti Setiati Source Type: research

A Survival Analysis of Successful and Poor Treatment Outcome Among Patients with Drug-Resistant Tuberculosis and the Associated Factors: A Retrospective Cohort Study
CONCLUSION: there was a difference survival rates between success treatment (cured) and poor treatment outcome (death) during six years of observation. Age of patients is a single-predictor in survival of death. While, HIV status and resistance status were predictors in survival of cured.PMID:34251347 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Putri Bungsu Machmud Dwi Gayatri Sudarto Ronoatmodjo Source Type: research

Tocilizumab as a Treatment for 'Cytokine Storm Syndrome' in COVID-19: A Case Report
Acta Med Indones. 2021 Apr;53(2):194-201.ABSTRACTCoronavirus disease 19 (COVID-19) which is caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), has been a problem worldwide, particularly due to the high rate of transmission and wide range of clinical manifestations. Acute respiratory distress syndrome (ARDS) and multiorgan failure are the most common events observed in severe cases and can be fatal. Cytokine storm syndrome emerges as one of the possibilities for the development of ARDS and multiorgan failure in severe cases of COVID-19. This case report describes a case of a 53-year-old male patient who...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Ari Fahrial Syam Ceva W Pitoyo Suhendro Suhendro Benny Zulkarnain Nuri D Indrasari Dita Aditianingsih Cosphiadi Irawan Adityo Susilo Cleopas M Rumende Ika P Wijaya Fera Ibrahim Menaldi Rasmin Idrus Alwi Dadang Makmun Source Type: research

A Beneficial Bipolar Hemiarthroplasty on a Centenarian in One Developing Country
We report arthroplasty in 100-year-old woman with right hip fracture and right Colles fracture; which benefits her a three year of active and qualified life. Despite her age, the patient was quite independent, active, and mobile beforehand. Hence a meticulous preoperative planning and post-operative rehabilitation were structured by a comprehensive medic and non-medic geriatric team. Cementless bipolar hemiarthroplasty was perfectly sufficient for the hip fracture under regional anesthesia while the Colles fracture was managed with a close reduction and plastering. Rehabilitation was started on Day-2 and continued weeks af...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Komang Agung Irianto Novira Widajanti Eko Julianto Swen Ien Ronald T M Panggabean Yudhisthira Pradnyan Kloping Source Type: research

Thrombotic Thrombocytopenic Purpura in Dengue Fever
Acta Med Indones. 2021 Apr;53(2):208-212.ABSTRACTThrombotic thrombocytopenic purpura is a rare but life threatening medical condition. Early recognition and treatment of thrombotic thrombocytopenic purpura is important especially in patients who do not present with the classic pentad to reduce the high mortality. Herein, we describe a case of a patient who does not fulfil the classic pentad features thrombotic thrombocytopenic purpura that was induced by dengue fever. The patients' initial full blood picture did not have all the typical features of microangiopathic haemolytic anaemia but there were fragmented red blood cel...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Tze Yuan Tee Rizna Abdul Cader Source Type: research

Type 2 Diabetes Mellitus and Cognitive Impairment
Acta Med Indones. 2021 Apr;53(2):213-220.ABSTRACTType 2 diabetes mellitus (T2DM) is strongly associated with lower performance on multiple domains of cognitive function and with structural abnormalities of the brain. With the growing epidemic of diabetes and aging population, neural complications of diabetes are expected to rise and becoming a challenge for future health implications. Understanding pathophysiology, factors associated with this complication, manifestation of cognitive impairment and various metabolic and neuroradiologic markers suggestive of this pathologic condition is crucial for proper management of this...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Johanda Damanik Em Yunir Source Type: research

Giant Recurrence Pituitary Adenoma After Three Times Transphenoidal Removal Surgery, One Craniotomy Procedure, and 30 Doses of External Radiotherapy
Acta Med Indones. 2021 Apr;53(2):221-224.ABSTRACTThis is a case of 42nd year-old woman with history of sight loss in her both eyes. She experienced headache and visual field decrease gradually since 2014. After several laboratory and imaging examinations, from her dynamic pituitary magnetic resonance imaging (MRI), it is concluded that she had a giant adenoma of the pituitary gland which compressed to her optic chiasm. From her pituitary laboratory hormone panel, it is revealed that the tumor is a non-functioning pituitary adenoma. From the neuro-ophthalmology (campimetry) examinations, she had papillae atrophy in her both...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Laurentius Aswin Pramono Em Yunir Tri Juli Edi Tarigan Syntia Nusanti Renindra A Aman Indrati Suroyo Source Type: research

Psychotherapy for Healthcare Provider During COVID-19 Pandemic: An Evidence Based Clinical Review
CONCLUSION: the physiological condition of health workers needs to get attention during the COVID-19 pandemic. Although there is no standard of therapy yet, psychotherapy could be an option as it is proven to be able to reduce anxiety, depression, and insomnia.PMID:34251353 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Hamzah Shatri Rudi Putranto Edward Faisal Fita Fitrianti Kresna Adhiatma Putri Zulmiyusrini Sonya Farah Diba Petrin R Lukman Source Type: research

The Management of Pulmonary Fibrosis in COVID-19
Acta Med Indones. 2021 Apr;53(2):233-241.ABSTRACTPulmonary fibrosis due to COVID-19 is recognized as sequel of ARDS characterized by failed alveolar re-epithelization, fibroblast activation, excessive collagen deposition and other extracellular matrix components that disrupt the normal lung architecture. There are risk factor for pulmonary fibrosis namely advanced age, severe ARDS infection, mechanical ventilation due to ventilator-induced lung injury, smoking and chronic alcoholism. Diagnosis of post-COVID pulmonary fibrosis can be made by clinical symptoms and characteristic finding from lung CT scan. To date, there is n...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Cleopas Martin Rumende Erwin C Susanto Truely P Sitorus Source Type: research

Pulmonary Fibrosis Caused by Severe COVID-19 Infection: Discharge May Not Be The End of Treatment
Acta Med Indones. 2021 Apr;53(2):141-142.ABSTRACTSince December 2019, COVID-19 caused by SARS-CoV-2 infection has been spread rapidly in the world. Beside acute respiratory distress syndrome found in acute phase of infection, there is also pulmonary fibrosis as a chronic complication due to COVID-19. With the global pandemic of COVID-19, more and more autopsy and puncture histopathological results have been published.Until now there is no specific therapy to handle post-inflammatory pulmonary fibrosis due to COVID-19 infection. Several studies are ongoing to determine an effective treatment for this chronic complication. W...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Cleopas Martin Rumende Source Type: research

Validation of the Indonesian Version of the Asian Diabetes Quality of Life Questionnaire
CONCLUSION: Indonesian version of Asian DQOL is a valid and reliable tool to measure quality of life of type 2 diabetes mellitus patients.PMID:34251341 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Hikmat Permana Michelle Vincentia Liem Nanny N M Soetedjo Source Type: research

Association of BsmI Polymorphisms in the Vitamin D Receptor Gene Among Indonesian Population with Diabetic Kidney Disease
CONCLUSION: the profile of BsmI polymorphisms in the vitamin D receptor gene in the Indonesian population were genotypes Bb (89.2%) and bb (10.8%). There was no association between BsmI polymorphisms in the vitamin D receptor gene and DKD. Duration of DM more than five years influenced the association between those variables.PMID:34251342 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Pringgodigdo Nugroho Aida Lydia Suhardjono Suhardjono Kuntjoro Harimurti Source Type: research

Frequency of Acute Kidney Injury in Patient Receiving Piperacillin - Tazobactam: A Hospital-based Study from Qatar
Acta Med Indones. 2021 Apr;53(2):156-163.ABSTRACTBACKGROUND: several studies have been reported piperacillin-tazobactam (TAZ / PIPC)-associated AKI with various frequencies. The aim of this study was to determine the frequency of TAZ/PIPC- associated AKI among our patients and to identify the risk factors for this clinical entity.METHODS: this retrospective cross-sectional study was conducted at Hamad General Hospital; it involved adult patients who were admitted from January 2017 to December 2017.RESULTS: we involved 917 patients, of whom 635 (69.25%) were males and 282 (30.75%) were females. The mean age of the patients ...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Fahmi Yousef Khan Ahmed M Abdalhadi Rashid Kazman Dalal Sideeg Mudawi Khalid Shariff Aasir Suliman Hammad Shabir Chaudhry Rohit Sharma Ahmed Elballat Abdel-Monem Badawi Yousif Awni Alshurafa Fateen Ata Source Type: research

The Correlation Between HbA1c and Neuropathy Disability Score in Type 2 Diabetes
CONCLUSION: there is a relationship between HbA1c level and the severity of diabetic neuropathy in Type 2 DM.PMID:34251344 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Ilsa Hunaifi I Gusti Ngurah Ommy Agustriadi I Gede Yasa Asmara Catharina Budyono Source Type: research

The Risk Factors of Multidrug-Resistant Organisms in Hospitalized Patients with Community-Acquired Pneumonia in Dr. Soetomo Hospital Surabaya, Indonesia
This study aimed to analyze MDRO as the etiology of hospitalized patients with CAP along with its risk factors in Dr. Soetomo Hospital as one of the top referral hospitals in east Indonesia.METHODS: this retrospective cohort study was conducted from January 2016 to December 2018. Data were collected from patients' medical records. Automatic Rapid Diagnosis (Phoenix TM) was used as a standard method for culture and susceptibility test. Various risk factors were analyzed for MDRO infection.RESULTS: five most common pathogens in hospitalized patients with CAP were Acinetobacter baumannii 244/1364 (17.9%), Klebsiella pneumonia...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Soedarsono Soedarsono Putu Dyah Widyaningsih Ni Made Mertaniasih Source Type: research

Factors Associated with Arterial Stiffness in Chronic Hemodialysis Patients in Jakarta: The Role of Hemodialysis Frequency and Pentraxin 3
CONCLUSION: predialysis PTX3 levels above 2.3 ng/ml were associated with arterial stiffness. There was no difference in arterial stiffness between patients with twice- and thrice-weekly hemodialysis.PMID:34251346 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Elizabeth Yasmine Wardoyo Ginova Nainggolan Ni Made Hustrini Siti Setiati Source Type: research

A Survival Analysis of Successful and Poor Treatment Outcome Among Patients with Drug-Resistant Tuberculosis and the Associated Factors: A Retrospective Cohort Study
CONCLUSION: there was a difference survival rates between success treatment (cured) and poor treatment outcome (death) during six years of observation. Age of patients is a single-predictor in survival of death. While, HIV status and resistance status were predictors in survival of cured.PMID:34251347 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Putri Bungsu Machmud Dwi Gayatri Sudarto Ronoatmodjo Source Type: research

Tocilizumab as a Treatment for 'Cytokine Storm Syndrome' in COVID-19: A Case Report
Acta Med Indones. 2021 Apr;53(2):194-201.ABSTRACTCoronavirus disease 19 (COVID-19) which is caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), has been a problem worldwide, particularly due to the high rate of transmission and wide range of clinical manifestations. Acute respiratory distress syndrome (ARDS) and multiorgan failure are the most common events observed in severe cases and can be fatal. Cytokine storm syndrome emerges as one of the possibilities for the development of ARDS and multiorgan failure in severe cases of COVID-19. This case report describes a case of a 53-year-old male patient who...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Ari Fahrial Syam Ceva W Pitoyo Suhendro Suhendro Benny Zulkarnain Nuri D Indrasari Dita Aditianingsih Cosphiadi Irawan Adityo Susilo Cleopas M Rumende Ika P Wijaya Fera Ibrahim Menaldi Rasmin Idrus Alwi Dadang Makmun Source Type: research

A Beneficial Bipolar Hemiarthroplasty on a Centenarian in One Developing Country
We report arthroplasty in 100-year-old woman with right hip fracture and right Colles fracture; which benefits her a three year of active and qualified life. Despite her age, the patient was quite independent, active, and mobile beforehand. Hence a meticulous preoperative planning and post-operative rehabilitation were structured by a comprehensive medic and non-medic geriatric team. Cementless bipolar hemiarthroplasty was perfectly sufficient for the hip fracture under regional anesthesia while the Colles fracture was managed with a close reduction and plastering. Rehabilitation was started on Day-2 and continued weeks af...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Komang Agung Irianto Novira Widajanti Eko Julianto Swen Ien Ronald T M Panggabean Yudhisthira Pradnyan Kloping Source Type: research

Thrombotic Thrombocytopenic Purpura in Dengue Fever
Acta Med Indones. 2021 Apr;53(2):208-212.ABSTRACTThrombotic thrombocytopenic purpura is a rare but life threatening medical condition. Early recognition and treatment of thrombotic thrombocytopenic purpura is important especially in patients who do not present with the classic pentad to reduce the high mortality. Herein, we describe a case of a patient who does not fulfil the classic pentad features thrombotic thrombocytopenic purpura that was induced by dengue fever. The patients' initial full blood picture did not have all the typical features of microangiopathic haemolytic anaemia but there were fragmented red blood cel...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Tze Yuan Tee Rizna Abdul Cader Source Type: research

Type 2 Diabetes Mellitus and Cognitive Impairment
Acta Med Indones. 2021 Apr;53(2):213-220.ABSTRACTType 2 diabetes mellitus (T2DM) is strongly associated with lower performance on multiple domains of cognitive function and with structural abnormalities of the brain. With the growing epidemic of diabetes and aging population, neural complications of diabetes are expected to rise and becoming a challenge for future health implications. Understanding pathophysiology, factors associated with this complication, manifestation of cognitive impairment and various metabolic and neuroradiologic markers suggestive of this pathologic condition is crucial for proper management of this...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Johanda Damanik Em Yunir Source Type: research

Giant Recurrence Pituitary Adenoma After Three Times Transphenoidal Removal Surgery, One Craniotomy Procedure, and 30 Doses of External Radiotherapy
Acta Med Indones. 2021 Apr;53(2):221-224.ABSTRACTThis is a case of 42nd year-old woman with history of sight loss in her both eyes. She experienced headache and visual field decrease gradually since 2014. After several laboratory and imaging examinations, from her dynamic pituitary magnetic resonance imaging (MRI), it is concluded that she had a giant adenoma of the pituitary gland which compressed to her optic chiasm. From her pituitary laboratory hormone panel, it is revealed that the tumor is a non-functioning pituitary adenoma. From the neuro-ophthalmology (campimetry) examinations, she had papillae atrophy in her both...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Laurentius Aswin Pramono Em Yunir Tri Juli Edi Tarigan Syntia Nusanti Renindra A Aman Indrati Suroyo Source Type: research

Psychotherapy for Healthcare Provider During COVID-19 Pandemic: An Evidence Based Clinical Review
CONCLUSION: the physiological condition of health workers needs to get attention during the COVID-19 pandemic. Although there is no standard of therapy yet, psychotherapy could be an option as it is proven to be able to reduce anxiety, depression, and insomnia.PMID:34251353 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Hamzah Shatri Rudi Putranto Edward Faisal Fita Fitrianti Kresna Adhiatma Putri Zulmiyusrini Sonya Farah Diba Petrin R Lukman Source Type: research

The Management of Pulmonary Fibrosis in COVID-19
Acta Med Indones. 2021 Apr;53(2):233-241.ABSTRACTPulmonary fibrosis due to COVID-19 is recognized as sequel of ARDS characterized by failed alveolar re-epithelization, fibroblast activation, excessive collagen deposition and other extracellular matrix components that disrupt the normal lung architecture. There are risk factor for pulmonary fibrosis namely advanced age, severe ARDS infection, mechanical ventilation due to ventilator-induced lung injury, smoking and chronic alcoholism. Diagnosis of post-COVID pulmonary fibrosis can be made by clinical symptoms and characteristic finding from lung CT scan. To date, there is n...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Cleopas Martin Rumende Erwin C Susanto Truely P Sitorus Source Type: research

Pulmonary Fibrosis Caused by Severe COVID-19 Infection: Discharge May Not Be The End of Treatment
Acta Med Indones. 2021 Apr;53(2):141-142.ABSTRACTSince December 2019, COVID-19 caused by SARS-CoV-2 infection has been spread rapidly in the world. Beside acute respiratory distress syndrome found in acute phase of infection, there is also pulmonary fibrosis as a chronic complication due to COVID-19. With the global pandemic of COVID-19, more and more autopsy and puncture histopathological results have been published.Until now there is no specific therapy to handle post-inflammatory pulmonary fibrosis due to COVID-19 infection. Several studies are ongoing to determine an effective treatment for this chronic complication. W...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Cleopas Martin Rumende Source Type: research

Validation of the Indonesian Version of the Asian Diabetes Quality of Life Questionnaire
CONCLUSION: Indonesian version of Asian DQOL is a valid and reliable tool to measure quality of life of type 2 diabetes mellitus patients.PMID:34251341 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Hikmat Permana Michelle Vincentia Liem Nanny N M Soetedjo Source Type: research

Association of BsmI Polymorphisms in the Vitamin D Receptor Gene Among Indonesian Population with Diabetic Kidney Disease
CONCLUSION: the profile of BsmI polymorphisms in the vitamin D receptor gene in the Indonesian population were genotypes Bb (89.2%) and bb (10.8%). There was no association between BsmI polymorphisms in the vitamin D receptor gene and DKD. Duration of DM more than five years influenced the association between those variables.PMID:34251342 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Pringgodigdo Nugroho Aida Lydia Suhardjono Suhardjono Kuntjoro Harimurti Source Type: research

Frequency of Acute Kidney Injury in Patient Receiving Piperacillin - Tazobactam: A Hospital-based Study from Qatar
Acta Med Indones. 2021 Apr;53(2):156-163.ABSTRACTBACKGROUND: several studies have been reported piperacillin-tazobactam (TAZ / PIPC)-associated AKI with various frequencies. The aim of this study was to determine the frequency of TAZ/PIPC- associated AKI among our patients and to identify the risk factors for this clinical entity.METHODS: this retrospective cross-sectional study was conducted at Hamad General Hospital; it involved adult patients who were admitted from January 2017 to December 2017.RESULTS: we involved 917 patients, of whom 635 (69.25%) were males and 282 (30.75%) were females. The mean age of the patients ...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Fahmi Yousef Khan Ahmed M Abdalhadi Rashid Kazman Dalal Sideeg Mudawi Khalid Shariff Aasir Suliman Hammad Shabir Chaudhry Rohit Sharma Ahmed Elballat Abdel-Monem Badawi Yousif Awni Alshurafa Fateen Ata Source Type: research

The Correlation Between HbA1c and Neuropathy Disability Score in Type 2 Diabetes
CONCLUSION: there is a relationship between HbA1c level and the severity of diabetic neuropathy in Type 2 DM.PMID:34251344 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Ilsa Hunaifi I Gusti Ngurah Ommy Agustriadi I Gede Yasa Asmara Catharina Budyono Source Type: research

The Risk Factors of Multidrug-Resistant Organisms in Hospitalized Patients with Community-Acquired Pneumonia in Dr. Soetomo Hospital Surabaya, Indonesia
This study aimed to analyze MDRO as the etiology of hospitalized patients with CAP along with its risk factors in Dr. Soetomo Hospital as one of the top referral hospitals in east Indonesia.METHODS: this retrospective cohort study was conducted from January 2016 to December 2018. Data were collected from patients' medical records. Automatic Rapid Diagnosis (Phoenix TM) was used as a standard method for culture and susceptibility test. Various risk factors were analyzed for MDRO infection.RESULTS: five most common pathogens in hospitalized patients with CAP were Acinetobacter baumannii 244/1364 (17.9%), Klebsiella pneumonia...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Soedarsono Soedarsono Putu Dyah Widyaningsih Ni Made Mertaniasih Source Type: research

Factors Associated with Arterial Stiffness in Chronic Hemodialysis Patients in Jakarta: The Role of Hemodialysis Frequency and Pentraxin 3
CONCLUSION: predialysis PTX3 levels above 2.3 ng/ml were associated with arterial stiffness. There was no difference in arterial stiffness between patients with twice- and thrice-weekly hemodialysis.PMID:34251346 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Elizabeth Yasmine Wardoyo Ginova Nainggolan Ni Made Hustrini Siti Setiati Source Type: research

A Survival Analysis of Successful and Poor Treatment Outcome Among Patients with Drug-Resistant Tuberculosis and the Associated Factors: A Retrospective Cohort Study
CONCLUSION: there was a difference survival rates between success treatment (cured) and poor treatment outcome (death) during six years of observation. Age of patients is a single-predictor in survival of death. While, HIV status and resistance status were predictors in survival of cured.PMID:34251347 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Putri Bungsu Machmud Dwi Gayatri Sudarto Ronoatmodjo Source Type: research

Tocilizumab as a Treatment for 'Cytokine Storm Syndrome' in COVID-19: A Case Report
Acta Med Indones. 2021 Apr;53(2):194-201.ABSTRACTCoronavirus disease 19 (COVID-19) which is caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), has been a problem worldwide, particularly due to the high rate of transmission and wide range of clinical manifestations. Acute respiratory distress syndrome (ARDS) and multiorgan failure are the most common events observed in severe cases and can be fatal. Cytokine storm syndrome emerges as one of the possibilities for the development of ARDS and multiorgan failure in severe cases of COVID-19. This case report describes a case of a 53-year-old male patient who...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Ari Fahrial Syam Ceva W Pitoyo Suhendro Suhendro Benny Zulkarnain Nuri D Indrasari Dita Aditianingsih Cosphiadi Irawan Adityo Susilo Cleopas M Rumende Ika P Wijaya Fera Ibrahim Menaldi Rasmin Idrus Alwi Dadang Makmun Source Type: research

A Beneficial Bipolar Hemiarthroplasty on a Centenarian in One Developing Country
We report arthroplasty in 100-year-old woman with right hip fracture and right Colles fracture; which benefits her a three year of active and qualified life. Despite her age, the patient was quite independent, active, and mobile beforehand. Hence a meticulous preoperative planning and post-operative rehabilitation were structured by a comprehensive medic and non-medic geriatric team. Cementless bipolar hemiarthroplasty was perfectly sufficient for the hip fracture under regional anesthesia while the Colles fracture was managed with a close reduction and plastering. Rehabilitation was started on Day-2 and continued weeks af...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Komang Agung Irianto Novira Widajanti Eko Julianto Swen Ien Ronald T M Panggabean Yudhisthira Pradnyan Kloping Source Type: research

Thrombotic Thrombocytopenic Purpura in Dengue Fever
Acta Med Indones. 2021 Apr;53(2):208-212.ABSTRACTThrombotic thrombocytopenic purpura is a rare but life threatening medical condition. Early recognition and treatment of thrombotic thrombocytopenic purpura is important especially in patients who do not present with the classic pentad to reduce the high mortality. Herein, we describe a case of a patient who does not fulfil the classic pentad features thrombotic thrombocytopenic purpura that was induced by dengue fever. The patients' initial full blood picture did not have all the typical features of microangiopathic haemolytic anaemia but there were fragmented red blood cel...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Tze Yuan Tee Rizna Abdul Cader Source Type: research

Type 2 Diabetes Mellitus and Cognitive Impairment
Acta Med Indones. 2021 Apr;53(2):213-220.ABSTRACTType 2 diabetes mellitus (T2DM) is strongly associated with lower performance on multiple domains of cognitive function and with structural abnormalities of the brain. With the growing epidemic of diabetes and aging population, neural complications of diabetes are expected to rise and becoming a challenge for future health implications. Understanding pathophysiology, factors associated with this complication, manifestation of cognitive impairment and various metabolic and neuroradiologic markers suggestive of this pathologic condition is crucial for proper management of this...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Johanda Damanik Em Yunir Source Type: research

Giant Recurrence Pituitary Adenoma After Three Times Transphenoidal Removal Surgery, One Craniotomy Procedure, and 30 Doses of External Radiotherapy
Acta Med Indones. 2021 Apr;53(2):221-224.ABSTRACTThis is a case of 42nd year-old woman with history of sight loss in her both eyes. She experienced headache and visual field decrease gradually since 2014. After several laboratory and imaging examinations, from her dynamic pituitary magnetic resonance imaging (MRI), it is concluded that she had a giant adenoma of the pituitary gland which compressed to her optic chiasm. From her pituitary laboratory hormone panel, it is revealed that the tumor is a non-functioning pituitary adenoma. From the neuro-ophthalmology (campimetry) examinations, she had papillae atrophy in her both...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Laurentius Aswin Pramono Em Yunir Tri Juli Edi Tarigan Syntia Nusanti Renindra A Aman Indrati Suroyo Source Type: research

Psychotherapy for Healthcare Provider During COVID-19 Pandemic: An Evidence Based Clinical Review
CONCLUSION: the physiological condition of health workers needs to get attention during the COVID-19 pandemic. Although there is no standard of therapy yet, psychotherapy could be an option as it is proven to be able to reduce anxiety, depression, and insomnia.PMID:34251353 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Hamzah Shatri Rudi Putranto Edward Faisal Fita Fitrianti Kresna Adhiatma Putri Zulmiyusrini Sonya Farah Diba Petrin R Lukman Source Type: research

The Management of Pulmonary Fibrosis in COVID-19
Acta Med Indones. 2021 Apr;53(2):233-241.ABSTRACTPulmonary fibrosis due to COVID-19 is recognized as sequel of ARDS characterized by failed alveolar re-epithelization, fibroblast activation, excessive collagen deposition and other extracellular matrix components that disrupt the normal lung architecture. There are risk factor for pulmonary fibrosis namely advanced age, severe ARDS infection, mechanical ventilation due to ventilator-induced lung injury, smoking and chronic alcoholism. Diagnosis of post-COVID pulmonary fibrosis can be made by clinical symptoms and characteristic finding from lung CT scan. To date, there is n...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Cleopas Martin Rumende Erwin C Susanto Truely P Sitorus Source Type: research

Pulmonary Fibrosis Caused by Severe COVID-19 Infection: Discharge May Not Be The End of Treatment
Acta Med Indones. 2021 Apr;53(2):141-142.ABSTRACTSince December 2019, COVID-19 caused by SARS-CoV-2 infection has been spread rapidly in the world. Beside acute respiratory distress syndrome found in acute phase of infection, there is also pulmonary fibrosis as a chronic complication due to COVID-19. With the global pandemic of COVID-19, more and more autopsy and puncture histopathological results have been published.Until now there is no specific therapy to handle post-inflammatory pulmonary fibrosis due to COVID-19 infection. Several studies are ongoing to determine an effective treatment for this chronic complication. W...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Cleopas Martin Rumende Source Type: research

Validation of the Indonesian Version of the Asian Diabetes Quality of Life Questionnaire
CONCLUSION: Indonesian version of Asian DQOL is a valid and reliable tool to measure quality of life of type 2 diabetes mellitus patients.PMID:34251341 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Hikmat Permana Michelle Vincentia Liem Nanny N M Soetedjo Source Type: research

Association of BsmI Polymorphisms in the Vitamin D Receptor Gene Among Indonesian Population with Diabetic Kidney Disease
CONCLUSION: the profile of BsmI polymorphisms in the vitamin D receptor gene in the Indonesian population were genotypes Bb (89.2%) and bb (10.8%). There was no association between BsmI polymorphisms in the vitamin D receptor gene and DKD. Duration of DM more than five years influenced the association between those variables.PMID:34251342 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Pringgodigdo Nugroho Aida Lydia Suhardjono Suhardjono Kuntjoro Harimurti Source Type: research

Frequency of Acute Kidney Injury in Patient Receiving Piperacillin - Tazobactam: A Hospital-based Study from Qatar
Acta Med Indones. 2021 Apr;53(2):156-163.ABSTRACTBACKGROUND: several studies have been reported piperacillin-tazobactam (TAZ / PIPC)-associated AKI with various frequencies. The aim of this study was to determine the frequency of TAZ/PIPC- associated AKI among our patients and to identify the risk factors for this clinical entity.METHODS: this retrospective cross-sectional study was conducted at Hamad General Hospital; it involved adult patients who were admitted from January 2017 to December 2017.RESULTS: we involved 917 patients, of whom 635 (69.25%) were males and 282 (30.75%) were females. The mean age of the patients ...
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Fahmi Yousef Khan Ahmed M Abdalhadi Rashid Kazman Dalal Sideeg Mudawi Khalid Shariff Aasir Suliman Hammad Shabir Chaudhry Rohit Sharma Ahmed Elballat Abdel-Monem Badawi Yousif Awni Alshurafa Fateen Ata Source Type: research

The Correlation Between HbA1c and Neuropathy Disability Score in Type 2 Diabetes
CONCLUSION: there is a relationship between HbA1c level and the severity of diabetic neuropathy in Type 2 DM.PMID:34251344 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - July 12, 2021 Category: Internal Medicine Authors: Ilsa Hunaifi I Gusti Ngurah Ommy Agustriadi I Gede Yasa Asmara Catharina Budyono Source Type: research