The Collateral Impacts of Pandemic.
Authors: Pitoyo CW Abstract A pandemic that covers the whole world occurs relatively in every 100 years. Thus, it can be said that no expert has ever experienced directly dealing with a global pandemic. In the absence of people who are truly experts who know the problems and impacts of a global pandemic, various studies need to be carried out extensively between fields and across regions in the world. Likewise, the results of the study need to be recorded permanently so that it can still be useful over a long period of time, preferably for more than a hundred years.Studies of the short-term and long-term impacts of...
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Correlation Between Adult Tobacco Smoking Prevalence and Mortality of Coronavirus Disease-19 Across the World.
CONCLUSION: there is correlation between the prevalence of adult male smoking and the CFR of COVID-19 in lower middle-income countries. Based on these findings, strengthening of tobacco control policies is essential to reduce the impact of the COVID-19 pandemic especially in LMIC. This still warrants further studies. PMID: 33377876 [PubMed - as supplied by publisher] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

The Association between Peripheral Th17, Th1, IL-17, and IFN- γ Levels and TACE Response in Patients with Unresectable Hepatocellular Carcinoma with or without Cirrhosis.
CONCLUSION: increased circulating Th1, Th17, and CD4+/IFN-γ+/IL-17+ T cells were observed in HCC patients with complete or partial response to TACE. PMID: 33377877 [PubMed - as supplied by publisher] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Soluble Transferrin Receptor (sTfR) Identifies Iron Deficiency Anemia (IDA) in Pulmonary Tuberculosis Patients.
CONCLUSION: the findings suggest verifying the sTfR amount in anemic patients with pulmonary TB suffering from inflammation, so that the iron deficiency could be more accurately identified and properly treated. PMID: 33377878 [PubMed - as supplied by publisher] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

The Impact of Frailty on 30-day Post-Elective Surgery Complications in Elderly Patients: a Prospective Cohort Study.
CONCLUSION: being frail increases the risk of 30-day post-elective surgery complications in elderly patients. PMID: 33377879 [PubMed - as supplied by publisher] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

The Role of TB-LAMP Method in Detecting Mycobacterium tuberculosis from Sputum of Patients Suspected of Having Pulmonary Tuberculosis.
CONCLUSION: TB-LAMP has both high sensitivity and negative predictive value. PMID: 33377880 [PubMed - as supplied by publisher] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Sexual Dysfunction Reduction in Female Patients with Chronic Kidney Disease Undergoing Continuous Ambulatory Peritoneal Dialysis.
CONCLUSION: women with CKD who underwent CAPD, had an increase in FSFI scores compared to before CAPD. Thus, the use of CAPD can be seen to reduce sexual dysfunction and therefore improve the quality of life of women with CKD. PMID: 33377881 [PubMed - as supplied by publisher] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

The Dominance of CRF01_AE and the Emergence of Drug Resistance Mutations Among Antiretroviral Therapy-Experienced, HIV-1-infected Individuals in Medan, Indonesia.
CONCLUSION: our study showed that the dominant subtype found in ART-experienced, HIV-1-infected individuals residing in Medan was CRF01_AE. The emergence of drug resistance mutations in RT and PR genes indicated the importance to monitor the prevalence of drug resistance mutations among HIV-1-infected individuals in Medan. PMID: 33377882 [PubMed - as supplied by publisher] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Misleading Diagnosis of Radiological Imaging of COVID-19 Pneumonia During Pandemic Era: Risk on the Existence of CMV Infection.
The objective of this case report is to raise vigilance towards other diseases that have radiological image similarities with COVID-19, especially in the immunocompromised patients who are susceptible to viral infections like CMV infection so that the delay in the disease treatment can be prevented. PMID: 33377883 [PubMed - as supplied by publisher] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Autologous Bone Marrow Transplant in Multiple Myeloma Patient With Bone Marrow Hematopoietic Stem Cell.
We report two cases with non-secretory myeloma stage III and IgG myeloma stage II (International Staging System). Both patients were treated with induction regimens CyBord until a complete remission. Once remission was achieved, an autologous bone marrow transplant procedures were performed. The source of haematopietic stem cells (HSCs) were harvested from bone marrow and stored for 24 hours at a temperature of 4◦ C. The complications were neutropenia, anemia, thrombocytopenia, mucositis, diarrhea, hair loss, and skin darkness. The HSCs grew well on day 12 and 23. After treatment in the isolation room, the patient's cond...
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

COVID-19 Vaccines: Current Status and Implication for Use in Indonesia.
Authors: Ophinni Y, Hasibuan AS, Widhani A, Maria S, Koesnoe S, Yunihastuti E, Karjadi TH, Rengganis I, Djauzi S Abstract The coronavirus disease 2019 (COVID-19) has inflicted catastrophic damages in public health, economic and social stability-putting life globally on hold in 2020 and presumably a year more. Indonesia bears a heavy burden of the pandemic, counting the highest case prevalence and fatality rate in all of Southeast Asia. One hope remains in the groundbreaking universal effort in search of a vaccine against the causative virus SARS-CoV-2, which has shown success unparalleled in human vaccine developme...
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Kidney Hyperfiltration After Nephrectomy: A Mechanism to Restore Kidney Function in Living Donors.
Authors: Marbun MB, Susalit E Abstract Living donor kidney transplantation (LDKT) is the treatment of choice for patients with end stage renal disease (ESRD). Up to now, the studies reporting the impact of nephrectomy in living kidney donors to their future kidney function were limited. Most living donors undergo recovery of kidney function after nephrectomy owing to remnant kidneys' capability to compensate nephron loss through adaptive hyperfiltration. However, hyperfiltration may fail and turn out to be maladaptive, causing deterioration of donors' kidney function and increasing risk of chronic kidney disease (C...
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Priapismus as Leukostasis Manifestation in Chronic Myeloid Leukemia.
We report a 44-year-old male patient presenting with priapism as the first manifestation of CML. PMID: 33377887 [PubMed - as supplied by publisher] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

COVID-19 in Indonesia: Challenges and Multidisciplinary Perspectives for a Safe and Productive New Normal.
Authors: Susanto AP, Findyartini A, Taher A, Susilaradeya DP, Ariawan I, Dartanto T, Takwin B, Prasodjo IB, Yusuf PA, Sudarmono PP, Syam AF, Wiweko B Abstract The COVID-19 pandemic has caused disruption in all aspects of life, and countries around the world have been combating this pandemic using multiple approaches. Success in one country does not guarantee a transferable approach to other countries with different contexts. This review describes the challenges of COVID-19 management in Indonesia as a populous, socially and culturally diverse, and archipelagic country. It aims to provide multidisciplinary perspecti...
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

A Clinical and Procedural Guideline for Gastrointestinal Endoscopy Units during COVID-19 Pandemic Era.
Authors: Maulahela H, Syam AF, Renaldi K, Bestari MB, Sutikno R, Abdullah M, Simadibrata M, Makmun D Abstract The World Health Organization (WHO) has declared COVID-19 as global pandemic since there are tremendous growing numbers of confirmed cases for SARS-C0V-2 infection, the number of affected countries and high mortality rate. The global COVID-19 pandemic also will affect various aspects of health care including endoscopic service. The Indonesian Society for Digestive Endoscopy (ISDE), which provides a scope for doctors who perform endoscopic procedures, has developed a clinical and procedural guideline that ma...
Source: Acta medica Indonesiana - January 1, 2021 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

COVID-19 in Indonesia: Where Are We?
Authors: Ariawan I, Jusril H Abstract Since the 1st case officially confirmed on the last March 2020, Indonesia recorded more than 1000 new cases daily. The national trend shows no sign of decrease as 19 September 2020 the report sets a new mark of 4000 new cases in a day. The concept of controlling disease transmission relies on contacts suppression; and on the longer end, relies on vaccinations. As 27 September 2020, no vaccine is approved for use in the general population. Until then, countries should implement early, widespread, and strict disease mitigation strategies. While much remains to be learned on ...
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Dilemma of Prioritising Health and the Economy During COVID-19 Pandemic in Indonesia.
Authors: Setiati S, Azwar MK Abstract Since the detection of the first confirmed case of coronavirus disease 2019 (COVID-19) in early March 2020, 248,852 cases have been detected in Indonesia by 21 September 2020. At least 100 doctors have died from COVID-19 nationwide. Full large-scale social restriction was a temporary measure, followed by an early transition to the new normal era during the never-ending first wave in the country. Workers in industrial, retail, transport, and tourism fields suffered a significant decrease in work. Many countries are, however, in dilemma of protecting the health of the citizens an...
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Clinical Profile of Elderly Patients with COVID-19 hospitalised in Indonesia's National General Hospital.
ConclusionMale patients dominated both confirmed cases and death cases among elderly with COVID-19. Classic symptoms of COVID-19 were only found in about half of the study patients. Non-survivors had higher percentage of the classic symptoms of COVID-19 than survivors. Atypical COVID-19 presentations are possible in older adults. We postulated that immunosenescence and sex-specific immunoregulatory function play an important role in causing death in this study cohort. Keywords: Clinical Profile, Elderly, Geriatric Patient, COVID-19, Indonesia. PMID: 33020331 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Test, Trace, and Treatment Strategy to Control COVID-19 Infection Among Hospital Staff in a COVID-19 Referral Hospital in Indonesia.
This study aimed to evaluate the 3T strategy to control COVID-19 infection in a COVID-19 Referral Hospital in Depok, West Java, Indonesia. METHODS: this is a cross-sectional study conducted at the University of Indonesia Hospital. The study was conducted in June 2020 with 742 participants (staff members) using secondary data from polymerase chain reaction (PCR) test results. We presented data in the descriptive form and performed bivariate analysis using the chi-square/Fischer test for categorical data. RESULTS: the PCR test results were positive in 83 (11.1%) participants, with a case-per-tracing ratio of 1:24 and...
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Factors Related to Knowledge, Perception, and Practices Towards COVID-19 Among Patients with Autoimmune Diseases: A Multicenter Online Survey.
CONCLUSION: almost all respondents had good knowledge and practices regarding COVID-19. Adequacy of information, autoimmune treatment, work from home, educational background, area of living, and health care facilities contributed to perception regarding COVID-19 pandemic. PMID: 33020333 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Risk factors and laboratory test results associated with severe illness and mortality in COVID-19 patients: A systematic review.
ConclusionAge>60 years, hypertension, DM, and coronary heart disease are the risk factors for severe illness of COVID-19. Laboratory test results associated with severe illness are serum LDH 250-500 U/L, LDH>500 U/L, and lymphopenia, whereas test results associated with mortality are CD3+CD8+ cell count ≤ 75 cell/μl, AKI stage 2 and 3, proteinuria ≥1+, hematuria ≥1+, D-dimer> 1 mg/L, peak serum creatinine> 13.26 μmol/L. PMID: 33020334 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Factors Associated with Death in COVID-19 Patients in Jakarta, Indonesia: An Epidemiological Study.
Authors: Rozaliyani A, Savitri AI, Setianingrum F, Shelly TN, Ratnasari V, Kuswindarti R, Salama N, Oktavia D, Widyastuti W, Handayani D Abstract BACKGROUND: Coronavirus Disease 2019 is an emerging respiratory disease that is now a pandemic. Indonesia is experiencing a rapid surge of cases but the local data are scarce. METHODS: this is an analysis using data from the ongoing recapitulation of Epidemiological Surveillance (ES) by the Provincial Health Office of Jakarta from March 2nd to April 27th 2020. We evaluated demographic and clinical characteristics of all confirmed cases in association with death. R...
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Effect of Antimuscarinic Drugs on Cognitive Functions in the Management of Overactive Bladder in Elderly.
CONCLUSION: the use of most antimuscarinics medication has little to no effect towards the cognitive function in the management of overactive bladder in elderly patients. However, Oxybutynin, Darifenacin, and Tolterodine was shown to have significant decrease in cognitive functions, as shown in the decline of total MMSE score. PMID: 33020336 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

The Effect of Hyperfiltration on Kidney Function in Living Donor Kidney Transplantation: A Prospective Cohort Study.
Authors: Marbun MBH, Susalit E, Aulia D, Pandelaki J, Bardosono S, Purwanto B Abstract BACKGROUND: living kidney donation is a safe medical procedure. Kidney function after donation is crucial for donors' health and quality of life. Kidney hyperfiltration is a compensatory mechanism, which will preserve kidney function after unilateral nephrectomy. The number of studies regarding hyperfiltration in living kidney donors is limited. Our study aimed to explain kidney hyperfiltration mechanism and evaluate its effect on the kidney function within 30 days after surgery. METHODS: our study was a prospective cohort st...
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Report of Two COVID-19 ARDS (CARDS) Cases Who Survived without Intubation and Mechanical Ventilation.
Authors: Soeroto AY, Hartantri Y, Perkusi JE, Ferdian F, Rehimat U, Suryadinata H Abstract The most severe clinical feature of COVID-19 is Acute Respiratory Distress Syndrome (ARDS) which requires intubation and mechanical ventilation and it occurs in approximately 2.3% of cases. About 94% of of these cases end in death. This case series report two confirmed COVID-19 patients who had met criteria of intubation and mechanical ventilation, but not performed to them. Both patients experienced clinical improvement and recovery. Probably this is due to differences of COVID-19 ARDS (CARDS) with typical or classic ARDS.&n...
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Diarrhea as an Early and Predominant Manifestation of Coronavirus Disease 2019 (COVID-19): A Case Report.
Authors: Darnindro N, Nurdewati L, Manurung A, Mokoagow MI, Nasarudin J, Wardoyo EY, Sari AP, Djojo AY, Iskandar M, Adji G, Epriliawati M, Mauleti I, Mulyana E, Harahap A Abstract Coronavirus disease 2019 (COVID-19) is a new infectious disease that spreads very rapidly and therefore, WHO has declared it as a global pandemic disease. The main clinical symptoms found in COVID-19 patients are cough and fever; however, in some cases, diarrhea can be one of the early symptoms. The present case report describes a patient who came with a complaint of diarrhea without fever and she was later confirmed to be positive for CO...
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Prevention of Ventricular Arrhythmia and Sudden Cardiac Death in COVID-19 Patients.
Authors: Yamin M, Demili AU Abstract Since the first case was reported at the end of 2019, COVID-19 has spread throughout the world and has become a pandemic. The high transmission rate of the virus has made it a threat to public health globally. Viral infections may trigger acute coronary syndromes, arrhythmias, and exacerbation of heart failure, due to a combination of effects including significant systemic inflammatory responses and localized vascular inflammation at the arterial plaque level. Indonesian clinical practice guideline stated that (hydroxy)chloroquine alone or in combination with azithromycin may be...
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Discordance Between Clinical Status and Chest X-Ray (CXR) in COVID-19 Patient with Asymptomatic Transmission in Jakarta.
Authors: Burhan E, Agustin H, Susanto AD, Dharmawan INIP, Meyer M, Rogayah R Abstract Coronavirus Disease 2019 (COVID-19) symptoms are highly various in each patient. CXR are routinely used to monitor the disease progression. However, it is not known whether chest X-Ray (CXR) is a good modality to assess COVID-19 pneumonia.Male, 55 years-old, with pneumonia caused by COVID-19. Discordance was found between patient's clinical status and CXR lesion. On the 7th day of symptoms, patient was clinically well despite severe lesion shown on CXR. On the following day, patient clinically deteriorated despite the improvement ...
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

COVID-19 pandemic in Indonesia: Situation and challenges of rehabilitation medicine in Indonesia.
Authors: Nugraha B, Wahyuni LK, Laswati H, Kusumastuti P, Tulaar AB, Gutenbrunner C Abstract AbstrakCOVID-19 telah menjadi pandemik di Indonesia sejak ditemukannya kasus pertama pada tanggal 2 Maret 2020 di Depok. Peningkatan kasus perhari semakin tinggi sejak akhir Agustus 2020 yang mencapai lebih dari 2000 kasus per hari. Sistem kesehatan di Indonesia perlu ditingkatkan dalam hal kapasitas, termasuk rehabilitasi medik yang harus dilibatkan dari fase akut hingga jangka panjang dalam penanganan pasien COVID-19. Rehabilitasi medik juga diperlukan untuk pasien lain yang bukan COVID-19. Pentingnya keterlibatan, pelaya...
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

The Management of Cytokine Storm in COVID-19.
This article review the pathogenesis and treatment strategies of COVID-19 virus-induced inflammatory storm in attempt to provide valuable medication guidance for clinical treatment. PMID: 33020343 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - October 8, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

A Call for Preventive Medicine Attention for Indonesian Physicians.
Authors: Pramono LA Abstract The year of 2020 teaches us to prevent is always better than to cure. It is an old phrase that is being used for decades, but it is never been implemented cordially by our society nowadays. Covid-19 is a good lesson that reminds us to carefully prevent the spread of coronavirus which is now a pandemic worldwide. People now wash their hands more often and clean, wear a mask everywhere - everytime, do physical distancing, do healthy lifestyle such as physical activity, healthy diet, and consume multivitamins. They obey the cough and sneeze etiquette. Prevention awareness is never been suc...
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

The Role of Acute Hyperglycemia on the Risk of Malignant Arrhythmia in Acute Myocardial Infarction Patients: A Study of Myocardial Damage, Ion Channel Changes and Inflammatory Factors.
CONCLUSION: it was concluded that the inititial stage of AMI causes more dominant myocardial damage, as compared to metabolic factors. In the next stage of AMI, acute hyperglycemia increases ROS and the activation of ion channel changes described by CaMKII. This change results in electrophysiological remodeling of the heart, as seen in the VLP image on SA-ECG. PMID: 32778623 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Poor Physical Function as a Risk Factor for Non-Communicable Diseases in Indonesia: A Retrospective Cohort Study.
CONCLUSION: poor physical function can be assessed to identify risk of diabetes, heart disease, and stroke. Healthcare personnel should provide education programs that inform patients on the importance of maintaining a healthy physical ability. PMID: 32778624 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Influence of Micronutrient Consumption by Tuberculosis Patients on the Sputum Conversion Rate: A Systematic Review and Meta-analysis Study.
CONCLUSION: micronutrient intervention during tuberculosis treatment has a positive effect toward to sputum conversion among patient. Zinc and retinol influence sputum conversion while vitamin D did not. PMID: 32778625 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

The Influence of New-Onset Atrial Fibrillation After Coronary Artery Bypass Grafting on Three-Year Survival.
CONCLUSION: new-onset atrial fibrillation after CABG independently decreases three-year survival. PMID: 32778626 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Effects of Extracardiac Factors in Signal-Averaged Electrocardiography-measured Late Potentials from Early Anterior Myocardial Infarction in Intensive Cardiac Care Unit.
CONCLUSION: patients with anterior MI who suffer from diabetes with hyperglycemia in admission, obesity, and dyslipidemia have a potentially higher LP prevalence, despite statistical insignificance. To increase the prognostic value of SA-ECG, serial examinations are needed during hospitalization. PMID: 32778627 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

The Association of Carcinoembryonic Antigen and Cytokeratin-19 Fragments 21-1 Levels with One-Year Survival of Advanced Non-Small Cell Lung Carcinoma at Cipto Mangunkusumo Hospital: A Retrospective Cohort Study.
CONCLUSION: from both tumour markers, only CYFRA 21-1 was proven to be significant to NSCLC survival. CYFRA 21-1 cut-off value as a prognostic factor was> 10.9 ng/mL. PMID: 32778628 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

The Difference in the Cyclin D1 Expression in Advanced Stage Nasopharyngeal Cancer based on Treatment Response: A Retrospective Cohort Study.
CONCLUSION: this study suggests that a higher expression of cyclin D1 is associated with a good treatment response in NPC patients. PMID: 32778629 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

A Family Cluster of Coronavirus Disease (COVID-19) Infection with Different Clinical Manifestations.
This report describes the epidemiological, clinical, radiological, laboratory findings, and different clinical manifestation of a family cluster of COVID-19 case in Indonesia. COVID-19 was transmitted from asymptomatic person in the incubation period. PMID: 32778630 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

The Role of Chest Radiograph, Procalcitonin and Moxifloxacin in Diagnosis and Management of Breast Cancer Patients with COVID-19.
Authors: Rinaldi I, Muthalib A, Astowo P, Irawan B, Susanto N, Magdalena L, Maha IHRT, Wicaksono S Abstract Global widespread of current coronavirus disease 2019 (COVID-19) pandemic has emerged huge predicament to healthcare systems globally. This disease caused by a new beta-type coronavirus, known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), may lead to systemic multiorgan dysfunction syndrome and subsequently cause death due to abundant angiotensin converting enzyme 2 as its functional receptors throughout body. Oncology patients even have a worse prognosis with greater infection susceptibili...
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Health Issues Among Healthcare Workers During COVID-19 Pandemic: a Psychosomatic Approach.
In conclusion, psychosomatic approach is important to keep the healthcare workers healthy. PMID: 32778632 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Acute Cerebellar Strokes with Anoxic Brain Injury After a Cardiopulmonary Arrest in SARS-CoV-2 Patient.
Authors: Janjua T, Moscote-Salazar LR Abstract Neurological complications from novel coronavirus is becoming more common. These patients usually have primary pulmonary problem of acute lung injury. Presentation in the form of encephalitis, meningitis, Guillain-Barre syndrome and seizures are noted. It is also noted that SARS-CoV-2 has predilection for brain stem leading to patient not feeling extensive pulmonary injury. Here we share another neurological presentation. PMID: 32778633 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Mass Panic Disaster Management in COVID-19 Pandemic.
Authors: Shatri H, Faisal E, Putranto R Abstract Coronavirus disease (COVID-19) pandemic occurred abruptly. It is an unexpected disaster. Uncertain treatment for this viral infection increases excessive anxiety, which does not occur only in one person but also in majority of people; therefore, it can create mass panic. Mass panic is a serious problem that must be immediately identified and managed. Mass panic management will reduce COVID-19 incidence. PMID: 32778634 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Palliative Management of Advanced Pancreatic Cancer: The Role of Gastroentero-hepatologist.
Authors: Adiwinata R, Livina A, Waleleng BJ, Tendean N, Gosal F, Rotty L, Winarta J, Waleleng A Abstract Pancreatic cancer commonly diagnosed at late stage due to subtle clinical manifestation and associated with low 5-year survival rate. Only 10-20% of patients were found in resectable or localized stage. Several complications may arise due to advanced pancreatic cancer such as obstructive jaundice, gastric outlet obstruction, pancreatic cancer cachexia, pruritus of cholestasis, and cancer pain. Palliative management should be optimized in order to improve patient's quality of life. A gastroentero-hepatologist sho...
Source: Acta medica Indonesiana - August 13, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Diagnosing COVID-19: Did We Miss Anything?
Authors: Tenda ED, Asaf MM Abstract In late 2019, a mass of patients showing symptoms of a pneumonia-like disease of unknown origin emerged in Wuhan, China. Little did the world know it was the prelude of what would be a devastating pandemic. Samples were collected from these patients and the use of unbiased sequencing, and subsequent isolation of the pathogen using human airway epithelial cells led to the discovery of a novel coronavirus, named 2019-nCoV by the World Health Organization (WHO) and Severe Acute Respiratory Syndrome CoronaVirus-2 (SARS-CoV-2) by the International Committee on Taxonomy of Viruses. The...
Source: Acta medica Indonesiana - April 17, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Sarcopenia and Frailty Profile in the Elderly Community of Surabaya: A Descriptive Study.
CONCLUSION: the prevalence of sarcopenia and frailty in the elderly is significantly high, thus, it is expected that this study results are used as a basis for subsequent research, especially to determine the sarcopenia cut-off, in accordance with Indonesian sociodemography. PMID: 32291366 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 17, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

IDENTIA Registry: Incidence of Deep Vein Thrombosis in Medically Ill Subjects at High Risk in Indonesia: A Prospective Study.
CONCLUSION: this study indicated that the incidence of DVT is high in medically ill patients in Indonesia and will provide new insights and awareness about DVT in Indonesia. PMID: 32291367 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 17, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Comparative Effectiveness of Tuberculosis Treatment Daily versus Intermittent Regimen in Indonesian TB-DM Patients: Real World Patient Database Study.
CONCLUSION: there is no difference between sputum conversion profile and treatment success in advanced phase TB-DM treatment category 1 between the daily and intermittent regimen.ly for diabetic patients. PMID: 32291368 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 17, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Six-month Survival of Patients with Malignant Distal Biliary Stricture Following Endoscopic Biliary Stent Procedure and Its Associated Factors.
Authors: Kusumaningtyas L, Makmun D, Syam AF, Setiati S Abstract BACKGROUND: unresectable malignant distal biliary stricture patients require endoscopic biliary stent placement procedure. The survival rate and its associated factors in Indonesia are unknown. OBJECTIVES: To identify 6-month survival of patients with malignant distal biliary stricture following endoscopic biliary stent procedure and its associated factors. METHODS: a retrospective cohort study was conducted using medical records of patients with unresectable malignant distal biliary stricture, which involved caput of pancreas, ampulla of Vate...
Source: Acta medica Indonesiana - April 17, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Three Years Survival of Elderly Cancer Patients in Indonesia: Do We Need a Different Approach?
CONCLUSION: the survival of elderly patients with cancer is affected by traditional prognostic factors. Advanced cancer stage was significant independent prognostic factor in female patients, while poor performance status was significant in male patients. PMID: 32291370 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 17, 2020 Category: Internal Medicine Tags: Acta Med Indones Source Type: research