Challenges in Diagnosis and Treatment of Male Hypogonadism
Acta Med Indones. 2024 Jan;56(1):1-2.ABSTRACTHypogonadism is a condition characterized by diminished or absent production of sex hormones by the testicles in men and the ovaries in women. Hypogonadism is classified into primary and secondary hypogonadism. Each type of hypogonadism can be caused by congenital and acquired factors. There are many factors that contribute to the occurrence of hypogonadism, including genetic and developmental disorders, infection, kidney disease, liver disease, autoimmune disorders, chemotherapy, radiation, surgery, and trauma. This represents the considerable challenge in diagnosing hypogonadi...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Dyah Purnamasari Source Type: research

The Impact on Working Conditions and Income Amongst Internists in Indonesia: Lesson Learned from the COVID-19 Pandemic
This study provides some lessons learned during the COVID-19 pandemic regarding the changes in working conditions and earnings experienced by Indonesian internists. There were 3,115 and 1,772 participants in the first and second survey, respectively. After one year, the proportion of internists handling COVID-19 cases, including critical COVID-19 cases, increased; with fewer internists over 60 years old involved. Working hours, number of patients, and monthly earnings decreased for the majority of internists. The increased workload was experienced by most participants one year of the pandemic, predominantly reported by fem...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Sally Aman Nasution Lugyanti Sukrisman Simon Salim Ni Made Hustrini Rudi Hidayat Evy Yunihastuti Ceva W Pitoyo Andhika Rachman Sayang Rahmadini Ginulur Gensyaf Adgani Nurul Inayah Rahmani Source Type: research

Impacts of the COVID-19 Pandemic on the CODE ST-Segment Elevation Myocardial Infarction Program: A Quantitative and Qualitative Analysis
CONCLUSION: The implementation of the code STEMI program during the COVID-19 pandemic revealed that modified pathways were required because of the COVID-19 screening process. According to the Donabedian model, during the pandemic, the code STEMI program's healthcare service quality decreased because of a reduction in efficacy, effectiveness, efficiency, and optimality. Despite these limitations attributed to the pandemic, the code STEMI program was able to provide good services for STEMI patients.PMID:38561885 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Eka Ginanjar Arif Mansjoer Lusiani Rusdi Rizky Ramadantie Hadiki Habib Lies Dina Liastuti Sally Aman Nasution Idrus Alwi Abdul Rashid Source Type: research

A Life-Threatening Complication During the Fourth Pregnancy Due to Acute Promyelocytic Leukemia: A Case Report
Acta Med Indones. 2024 Jan;56(1):76-83.ABSTRACTIncidents of leukemia in pregnancy are infrequent with only one case found from 75,000 to 100,000 pregnancies. The pathophysiological mechanism of leukemia during pregnancy is still unclear. Leukemia which occurs in pregnancy is usually acute and predominantly the myeloid type.A 35-year-old woman in her fourth pregnancy with a gestational age of 38-39 weeks, came to the emergency department (ED) with complaints of contractions since 4.5 hours before admission. The contraction was not accompanied by discharge, mucus, or blood, and fetal movements was still active. She denied co...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Ismy Azizah Sisnawati Kezia Salay Listiana Nur Fadillah Indi Jazilah Jessica Amelinda Mintarjo Atiyatum Billah Agung Sunarko Putra I Dewa Made Widi Hersana Citra Novita Source Type: research

Endoscopic Dilatation with Ultrathin Endoscope Assisted Method for Esophageal and Pyloric Stricture related Corrosive Injury: 4 Years Case Series Study
Acta Med Indones. 2024 Jan;56(1):84-92.ABSTRACTCorrosive injuries (CI) become medical problems related complications include esophageal, pyloric stricture and squamous cell carcinoma, physical and quality of life. Endoscopic (ED) dilatation is primary therapy. The ultrathin endoscope-assisted method is potentially safe and useful in avoiding technical failure. Describe clinical outcomes of ED ED-related CI including successful, refractory, recurrent, and complications-related procedures. Case series study of esophageal and/or pyloric stricture patients after CI who underwent dilatation at Soetomo General Hospital (July 201...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Rusdiyana Ekawati Nurike Setyari Mudjari Arianti Arianti Annisa Zahra Mufida Budi Widodo Titong Sugihartono Herry Purbayu Source Type: research

Identifying Predictors of Mortality in Sepsis Patients with Malignancy: A Retrospective Cohort Study
CONCLUSION: SOFA score and ECOG performance status are significantly associated with sepsis patient mortality in malignancy cases.PMID:38561888 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Leonard Nainggolan Rido Prama Eled Ikhwan Rinaldi Cleopas Martin Rumende Chyntia Olivia Maurine Jasirwan Suryo Anggoro Kusumo Wibowo Robert Sinto Khie Chen Lie Source Type: research

Health Literacy Among University Students in the COVID-19 Pandemic: A Systematic Review
CONCLUSION: University students around the world should have courses about health literacy according to university disciplines. These courses should be available for students of different fields to enhance their effectiveness, and training should be associated with students' needs and their subgroup traits.PMID:38561889 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Mohammadreza Arzaghi Neda Tizro Parna Ghannadikhosh Parisa Alsadat Dadkhah Razieh Mohammadi-Dashtaki Saleh Behzadi Fereshteh Sohrabivafa Kiana Naghavi Ali Sanaye Abbasi Ali Darroudi Mohammad Abbasalizadeh Ali Kheirandish Mohadeseh Poudineh Niloofar Deravi Source Type: research

Unusual Presentation of Unilateral Choroidal Melanoma with Bilateral Vasculitis in Young Individual: A Case Report and Review of Literature
Acta Med Indones. 2024 Jan;56(1):102-106.ABSTRACTOcular melanoma stands as the predominant primary intraocular malignancy, albeit infrequently exhibiting ipsilateral inflammatory manifestations. In this article, we present an exceptional case involving a middle-aged male who presented with unilateral ocular choroidal melanoma alongside bilateral retinal vasculitis. The patient initially received temporary steroid treatment, followed by brachytherapy, which contributed to the resolution of vasculitis symptoms. The study aims to document the atypical occurrence of bilateral retinal vasculitis, which could potentially masquer...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Saleh S Algamdi Dhoha M Alhamad Source Type: research

Effectiveness and Safety of Nebulized Magnesium as Last Line Treatment in Adults with Acute Asthma Attack: A Systematic Review and Meta-Analysis
CONCLUSION: Inhaled magnesium improves the outcome of asthmatic patients, especially in lung function, clinical severity, and respiratory rate. Moreover, inhaled magnesium is safe to be given.PMID:38561891 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Danny Darmawan Iris Rengganis Cleopas Martin Rumende Hamzah Shatri Soekamto Koesnoe Yogi Umbarawan Rudi Putranto Sally Aman Nasution Source Type: research

Effectivity of Bromocriptine Administration Towards Prolactin Positive Breast Cancer Receiving Anthracycline-Based Chemotherapy: A Literature Review
Acta Med Indones. 2023 Oct;55(4):465-474.ABSTRACTBreast cancer is among the deadliest gynecology cancers in the world. However, the management of advanced-stage breast cancer is often harder as a result of chemoresistance. This review aimed to discover the effect of bromocriptine on prolactin-positive breast cancer patients who received anthracycline-based chemotherapy. It is known that anthracycline works by inhibiting topoisomerase IIα (TOP2A), forming free radicals, binding DNA, and altering cell homeostasis, hence stopping the cell cycle and inducing cell death. However, reduction of TOP2A expression and increased glu...
Source: Acta medica Indonesiana - January 12, 2024 Category: Internal Medicine Authors: Muhammad Yadi Permana Sarwanti Sarwanti Siti Fauziah Source Type: research

Risk Factors for Declined Functional Status within 30 days After Elective Surgeries in Elderly Patients: A Prospective Cohort Study
CONCLUSION: Risk factors for declined functional status within 30 days after elective surgery in older patients are postoperative complications, preoperative functional status, hypoalbuminemia, and male gender.PMID:38213042 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - January 12, 2024 Category: Internal Medicine Authors: Yudo Murti Mupangati Henry Setyawan Czeresna Heriawan Soejono Muhammad Hussein Gasem Ignatius Riwanto Source Type: research

Effect of Extra-Virgin Olive Oil on Hand Foot Syndrome and hs-CRP in Patients Receiving Capecitabine: A Randomized Trial
CONCLUSION: This study demonstrates the potential benefits of incorporating unrefined EVOO into the regimen of patients undergoing capecitabine chemotherapy. EVOO supplementation was associated with lower incidences of HFS and a reduction in hs-CRP levels, indicating its possible role in preventing HFS development and mitigating inflammation.PMID:38213043 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - January 12, 2024 Category: Internal Medicine Authors: Yenny Dian Andayani Mgs Irsan Saleh Aru Wisaksono Sudoyo Zulkhair Ali Legiran Legiran Radiyati Umi Partan Eddy Yuristo Fadhyl Zuhry Lubis Source Type: research

Hypokalemia Related to Distal Renal Tubular Acidosis as an Initial Presentation of Primary Sjogren's Syndrome
Acta Med Indones. 2023 Oct;55(4):449-454.ABSTRACTHypokalemia due to loss of potassium through the kidneys can be caused by distal Renal Tubular Acidosis (dRTA). The etiology of dRTA can be primary due to genetic defects or secondary to autoimmune diseases, especially Sjogren's syndrome (SS). The occurrence of dRTA in SS patients is low, at only 5% of cases. This case was interesting because dRTA was the initial clinical manifestation that led to the diagnosis of SS in the patient. A 48-year-old woman came with complaints of recurrent weakness. The patient was routinely hospitalized with severe hypokalemia and received pota...
Source: Acta medica Indonesiana - January 12, 2024 Category: Internal Medicine Authors: I Gede Yasa Asmara Maruhum Bonar Hasiholan Marbun Source Type: research

Myocarditis Presenting as Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) in a Young Man: A Case Report
Acta Med Indones. 2023 Oct;55(4):455-459.ABSTRACTMyocardial infarction with non-obstructive coronary arteries (MINOCA) is a unique disorder that manifests as an acute myocardial infarction clinically without overt coronary arteries obstruction on angiography. Herein, we report a 17-year-old male presented with a chest pain occurring 3 hours before admission and fever lasting for 2 days. Electrocardiogram examination showed ST elevation in lead II, III, aVF and V3-V6. Laboratory tests results showed a normal leukocyte level of 9850/µL, an elevated troponin of 3.55 ng/mL and an elevated quantitative CRP of 46 mg/L. Coronary...
Source: Acta medica Indonesiana - January 12, 2024 Category: Internal Medicine Authors: Giovanni Reynaldo Rachmat Hamonangan Princella Monica Source Type: research

Advancing The Cardiovascular Care in Cancer Patients on Chemotherapy
Acta Med Indones. 2023 Oct;55(4):494-501.ABSTRACTCardiotoxicity associated with chemotherapy, also known as Cancer Therapy-Related Cardiac Dysfunction (CTRCD), affects 10% of patients undergoing chemotherapy and is the most undesirable side effect of chemotherapy. Over time, it is anticipated that there would be an increase in the number of cancer patients receiving treatments that could harm their cardiovascular systems. Physicians should choose whether to continue, halt, delay, or reduce the dose of chemotherapeutic drugs to reduce the impact of cardiotoxicity. Cardiotoxicity screening and diagnosis need a variety of met...
Source: Acta medica Indonesiana - January 12, 2024 Category: Internal Medicine Authors: Muhammad Yamin Simon Salim Muhammad Syahrir Azizi Lusiani Rusdi Aru Wisaksono Sudoyo Anneira Amanda Putri Source Type: research