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Correlation study on microbial communities and volatile flavor compounds in cigar tobacco leaves of diverse origins
Appl Microbiol Biotechnol. 2024 Feb 26;108(1):236. doi: 10.1007/s00253-024-13032-6.ABSTRACTTo elucidate the significant influence of microorganisms on geographically dependent flavor formation by analyzing microbial communities and volatile flavor compounds (VFCs) in cigar tobacco leaves (CTLs) obtained from China, Dominica, and Indonesia. Microbiome analysis revealed that the predominant bacteria in CTLs were Staphylococcus, Aerococcus, Pseudomonas, and Lactobacillus, while the predominant fungi were Aspergillus, Wallemia, and Sampaiozyma. The microbial communities of CTLs from different origins differed to some extent, a...
Source: Applied Microbiology and Biotechnology - February 26, 2024 Category: Microbiology Authors: Haiqing Wang Dongfeng Guo Mingzhu Zhang Guanglong Wu Yaqi Shi Jinglong Zhou Naihong Ding Xiangsong Chen Xingjiang Li Source Type: research

"I think they should give primary health care a little more priority". The primary health care in Caribbean SIDS: what can be said about adaptation to the changing climate? The case of Dominica- a qualitative study
CONCLUSION: The primary health care system is a key stakeholder in the design and operationalization of adaptation and transformative resilience. The Essential Public Health Functions should integrate social and climate and other environmental determinants of health to guide primary care activities to protect the health of communities. This study highlights the need for improved research on the linkages between climate events and health outcomes, surveillance, and development of plans informed by contextual knowledge in the SIDS.PMID:38388362 | PMC:PMC10882746 | DOI:10.1186/s12875-024-02311-w (Source: Primary Care)
Source: Primary Care - February 22, 2024 Category: Primary Care Authors: Fiona Harris-Glenville Patrick Cloos Source Type: research

Culturally responsive evaluation and emergence: Shifting power through data that is humanizing, liberatory, and healing
AbstractIn the process of developing a complicated, community-driven evaluation initiative, Dr. Stafford Hood indicated the importance of allowing the project to “unfold as it should.” This indication of emergence is too often missing in the dialogue of what it means to do Culturally Responsive Evaluation. This chapter explores and elucidates the concept of emergence and presents two examples of how it has influenced evaluation practice and enhanced the ongoing application of culturally responsive frameworks. The authors provide examples rooted in Dr. Hood's childhood home community while showcasing the power of simple...
Source: New Directions for Evaluation - February 14, 2024 Category: Universities & Medical Training Authors: Dominica McBride, Gabriela Garcia, Scott Christian Tags: ORIGINAL ARTICLE Source Type: research

Trehalose 6-phosphate synthase gene rdtps1 contributes to thermal acclimation in Rhyzopertha dominica
The lesser grain borer (Rhyzopertha dominica), a worldwide primary pest of stored grain, causes serious economic losses and threatens stored food safety. R. dominica can respond to changes in temperature, especia... (Source: BMC Genomics)
Source: BMC Genomics - February 13, 2024 Category: Genetics & Stem Cells Authors: Dingrong Xue, Yan Yang, Liwei Fang, Shibo Wang and Yi Wu Tags: Research Source Type: research

GSE235595 Structure-guided design of a selective inhibitor of the methyltransferase KMT9 with cellular activity
Contributors : Roland Sch üle ; Sheng Wang ; Eric Metzger ; Dominica WillmannSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensInhibition of epigenetic regulators by small molecules is an attractive strategy for cancer treatment. Recently, we characterised the role of lysine methyltransferase 9 (KMT9) in prostate, lung, and colon cancer. Our observation that the enzymatic activity was required for tumour cell proliferation identified KMT9 an attractive therapeutic target. Here, we report the development of the first-in-class, potent and selective KMT9 inhibitor (compound 4, KMI169)...
Source: GEO: Gene Expression Omnibus - December 31, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

Acyl ghrelin increases cardiac output while preserving right ventricular ‐pulmonary arterial coupling in heart failure
ConclusionTreatment with acyl ghrelin increases CO while preserving or even improving RVPAC in HFrEF, possibly due to increased contractility, reduced PVR and/or reduced left sided filling pressures. These potential effects strengthen the role of acyl ghrelin therapy in HFrEF with right ventricular failure. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 30, 2023 Category: Cardiology Authors: Mikael Erhardsson, Ulrika L. Fax én, Ashwin Venkateshvaran, Camilla Hage, Gianluigi Pironti, Tonje Thorvaldsen, Dominic‐Luc Webb, Per M. Hellström, Daniel C. Andersson, Marcus Ståhlberg, Lars H. Lund Tags: Short Communication Source Type: research

Prevalence of Multiple Causes of Death Within Young and Middle-Aged People Experiencing Sudden Cardiac Arrest
Multiple causes of death are increasingly reported, particularly in older populations. Rates of multiple causes of young sudden death have not been quantified. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - November 29, 2023 Category: Cardiology Authors: Elizabeth D. Paratz, Cassandra Spanos, Stephanie Rowe, Louise Fahy, Ziad Nehme, Dion Stub, Dominica Zentner, Paul James, Andreas Pflaumer, Vanessa Connell, Christopher Semsarian, Jodie Ingles, Andre La Gerche Tags: Original Article Source Type: research

French-speaking Swiss physician ’s perceptions and perspectives regarding their competencies and training need in leadership and management: a mixed-methods study
Effective leadership and management (L&M) are essential to the success of health care organizations. Young medical leaders often find themselves ill-prepared to take on these new responsibilities, but rarely a... (Source: BMC Health Services Research)
Source: BMC Health Services Research - October 12, 2023 Category: General Medicine Authors: R. L üchinger, M-C. Audétat, N. M. Bajwa, A-C. Bréchet-Bachmann, I. Guessous, H. Richard-Lepouriel, M. Dominicé Dao and Junod Perron Tags: Research Source Type: research

Competition of Rhyzopertha dominica and Sitophilus oryzae on six sorghum varieties
Environ Sci Pollut Res Int. 2023 Oct 5. doi: 10.1007/s11356-023-29807-9. Online ahead of print.ABSTRACTWe tested the effect of simultaneous infestation by adults of the lesser grain borer, Rhyzopertha dominica (F.) and the rice weevil, Sitophilus oryzae (L.) on six sorghum varieties. For this purpose, vials containing sorghum and either each species alone or both species were placed at 30 °C and 65% relative humidity. After ten days, all parental adults were removed and the vials were returned to the same conditions. Five weeks later the vials were emptied, to record adult emergence, the percentage of insect damaged kerne...
Source: Environmental Science and Pollution Research International - October 5, 2023 Category: Environmental Health Authors: Paraskevi Agrafioti Frank H Arthur Christos G Athanassiou Source Type: research

CO 2 emissions in Latin America: a time series perspective based on fractional integration
This article deals with the analysis of [Formula: see text] emissions in Latin America by using a long memory process based on fractional integration. Using data of [Formula: see text] emission and [Formula: see text] emissions per capita, for 32 Latin American and Caribbean countries, the results show significant differences according to the variable examined, the model used, and the country under examination. In particular, for the [Formula: see text] emissions, mean reversion is found in Belize and also under some circumstances in Antigua and Barbuda, Colombia, Dominica, Dominican Republic, Ecuador, Grenada, Honduras, N...
Source: Environmental Science and Pollution Research International - September 30, 2023 Category: Environmental Health Authors: Luis Rodrigo Asturias-Schaub Luis Alberiko Gil-Alana Source Type: research

Lower dose of plant substance more effective in repelling Rhyzopertha dominica F . (Coleoptera, Bostrichidae) and Sitophilus granarius L. (Coleoptera, Dryophthoridae)
CONCLUSIONS: The most interesting results were obtained concerning the relationship: the lower tested substance concentration caused a much stronger repellent effect of R. dominica and S. granarius..PMID:37772516 | DOI:10.26444/aaem/163326 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - September 29, 2023 Category: Environmental Health Authors: Aleksandra Maria Izdebska Ma łgorzata Kłyś Magdalena Nowak-Chmura Sylwia Koczanowicz Source Type: research