The new drugs preventing allergic reactions to peanuts and other foods
Incredible results from trials of several new medications show they can prevent potentially deadly reactions to foods like peanuts, eggs and dairy - and may one day treat asthma (Source: New Scientist - Health)
Source: New Scientist - Health - May 1, 2024 Category: Consumer Health News Source Type: research

Therapeutic administration of Luteolin protects against Escherichia coli-derived Lipopolysaccharide-triggered Inflammatory Response and Oxidative Injury
Acta Trop. 2024 Apr 29:107236. doi: 10.1016/j.actatropica.2024.107236. Online ahead of print.ABSTRACTEndometritis reduces reproductive effectiveness and leads to significant financial losses in the dairy sector. Luteolin is a natural phyto-flavonoid compound with many biological activities. However, the therapeutic effect of Luteolin against lipopolysaccharides (LPS)-induced endometritis has not yet been explored. A total of eighty female Kunming mice were randomly assigned into four treatment groups (n = 20). Following a successful initiation of the endometritis model by LPS, Luteolin was intraperitoneally administered th...
Source: Acta Tropica - May 1, 2024 Category: Infectious Diseases Authors: Aftab Shaukat Shahid Ali Rajput Mehboob Ali Rizwan Shukat Sana Hanif Mubashar Hassan Dalia Fouad Farid S Ataya Irfan Shaukat Arfan Yousaf Shadab Shaukat Renwei Su Source Type: research

Omics analysis revealed the intestinal toxicity induced by aflatoxin B1 and aflatoxin M1
In conclusion, the hazardous impact of co-exposure to AFB1 and AFM1 from proteomic perspectives was demonstrated in the present study.PMID:38691883 | DOI:10.1016/j.ecoenv.2024.116336 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - May 1, 2024 Category: Environmental Health Authors: Ya-Nan Gao Zi-Wei Wang Chuan-You Su Jia-Qi Wang Nan Zheng Source Type: research

Therapeutic administration of Luteolin protects against Escherichia coli-derived Lipopolysaccharide-triggered Inflammatory Response and Oxidative Injury
Acta Trop. 2024 Apr 29:107236. doi: 10.1016/j.actatropica.2024.107236. Online ahead of print.ABSTRACTEndometritis reduces reproductive effectiveness and leads to significant financial losses in the dairy sector. Luteolin is a natural phyto-flavonoid compound with many biological activities. However, the therapeutic effect of Luteolin against lipopolysaccharides (LPS)-induced endometritis has not yet been explored. A total of eighty female Kunming mice were randomly assigned into four treatment groups (n = 20). Following a successful initiation of the endometritis model by LPS, Luteolin was intraperitoneally administered th...
Source: Acta Tropica - May 1, 2024 Category: Infectious Diseases Authors: Aftab Shaukat Shahid Ali Rajput Mehboob Ali Rizwan Shukat Sana Hanif Mubashar Hassan Dalia Fouad Farid S Ataya Irfan Shaukat Arfan Yousaf Shadab Shaukat Renwei Su Source Type: research

Comprehensive analysis of differences in the physiochemical composition of foremilk and hindmilk of grazing indigenous and crossbred dairy goats; implications for growth, milk production and industry
This study was conducted on 90 grazing Hair, Alpine × Hair F1 (AHF1), and Saanen × Hair F1 (SHF1) crossbred goats in three farms located around the Taurus Mountains in Konya, T ürkiye. The study investigated variation in milk production, physico-chemical traits of milk fractions (foremilk, hindmilk and total milk), and growth traits. Genotype, parity, offspring sex, birth type, and flock factors significantly influenced milk production and quality traits of milk fractions (P <  0.05 toP <  0.01). Does with male/single offspring produced less milk, but with higher nutrient density (P <  0.05). Hindmi...
Source: Tropical Animal Health and Production - May 1, 2024 Category: Veterinary Research Source Type: research

Effects of yak rumen anaerobic fungus Orpinomyces sp. YF3 fermented on in vitro wheat straw fermentation and microbial communities in dairy goat rumen fluid, with and without fungal flora
In conclusion, supplementing rumen fer mentation media with yak rumen anaerobic fungusOrpinomyces sp. YF3 led to an increase in bacteria associated with fibre degradation and acetic acid production, a decrease in propionate-producing bacteria, enhanced the activity of plant cell wall degrading enzymes, and promoted cellulose degradation, ultimately elevating total VAF concentration and acetate proportion. This presents a novel approach to enhance roughage utilization in ruminants. (Source: Journal of Animal Physiology and Animal Nutrition)
Source: Journal of Animal Physiology and Animal Nutrition - April 30, 2024 Category: Zoology Authors: Xueer Du, Linlin Zhou, Yong Li, Fan Zhang, Lamei Wang, Junhu Yao, Xinghua Chen, Shimin Liu, Yangchun Cao Tags: ORIGINAL ARTICLE Source Type: research

Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024
We report highly pathogenic avian influenza A(H5N1) virus in dairy cattle and cats in Kansas and Texas, United States, which reflects the continued spread of clade 2.3.4.4b viruses that entered the country in late 2021. Infected cattle experienced nonspecific illness, reduced feed intake and rumination, and an abrupt drop in milk production, but fatal systemic influenza infection developed in domestic cats fed raw (unpasteurized) colostrum and milk from affected cows. Cow-to-cow transmission appears to have occurred because infections were observed in cattle on Michigan, Idaho, and Ohio farms where avian influenza virus-in...
Source: Emerging Infectious Diseases - April 29, 2024 Category: Infectious Diseases Authors: Eric R Burrough Drew R Magstadt Barbara Petersen Simon J Timmermans Phillip C Gauger Jianqiang Zhang Chris Siepker Marta Mainenti Ganwu Li Alexis C Thompson Patrick J Gorden Paul J Plummer Rodger Main Source Type: research

Genomic prediction of blood biomarkers of metabolic disorders in Holstein cattle using parametric and nonparametric models
CONCLUSIONS: Our results indicate that the Stack approach was more accurate in predicting metabolic disturbances than GBLUP, BayesB, ENET, and GBM and seemed to be competitive for predicting complex phenotypes with various degrees of mode of inheritance, i.e. additive and non-additive effects. Selecting markers based on GBM improved accuracy of GBLUP.PMID:38684971 | DOI:10.1186/s12711-024-00903-9 (Source: Genet Sel Evol)
Source: Genet Sel Evol - April 29, 2024 Category: Genetics & Stem Cells Authors: Lucio F M Mota Diana Giannuzzi Sara Pegolo Enrico Sturaro Daniel Gianola Riccardo Negrini Erminio Trevisi Paolo Ajmone Marsan Alessio Cecchinato Source Type: research

Effect of dietary supplementation of plantain herb, lemongrass and their combination on milk yield, immunity, liver enzymes, serum, and milk mineral status in dairy cows
CONCLUSIONS: Both plantain and lemongrass improved dairy cows' DM consumption and milk yield. Plantain and/or lemongrass enhanced the immune system and liver health, but not serum and milk calcium and phosphorus level. Lemongrass and a combination of plantain and lemongrass increased the serum and milk zinc concentrations.PMID:38680813 | PMC:PMC11055577 | DOI:10.5455/javar.2024.k764 (Source: Adv Data)
Source: Adv Data - April 29, 2024 Category: Epidemiology Authors: Md Aliar Rahman Md Rahat Ahmad Redoy Rakhi Chowdhury Mohammad Al-Mamun Source Type: research

Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024
We report highly pathogenic avian influenza A(H5N1) virus in dairy cattle and cats in Kansas and Texas, United States, which reflects the continued spread of clade 2.3.4.4b viruses that entered the country in late 2021. Infected cattle experienced nonspecific illness, reduced feed intake and rumination, and an abrupt drop in milk production, but fatal systemic influenza infection developed in domestic cats fed raw (unpasteurized) colostrum and milk from affected cows. Cow-to-cow transmission appears to have occurred because infections were observed in cattle on Michigan, Idaho, and Ohio farms where avian influenza virus-in...
Source: Emerging Infectious Diseases - April 29, 2024 Category: Infectious Diseases Authors: Eric R Burrough Drew R Magstadt Barbara Petersen Simon J Timmermans Phillip C Gauger Jianqiang Zhang Chris Siepker Marta Mainenti Ganwu Li Alexis C Thompson Patrick J Gorden Paul J Plummer Rodger Main Source Type: research

Genomic prediction of blood biomarkers of metabolic disorders in Holstein cattle using parametric and nonparametric models
CONCLUSIONS: Our results indicate that the Stack approach was more accurate in predicting metabolic disturbances than GBLUP, BayesB, ENET, and GBM and seemed to be competitive for predicting complex phenotypes with various degrees of mode of inheritance, i.e. additive and non-additive effects. Selecting markers based on GBM improved accuracy of GBLUP.PMID:38684971 | PMC:PMC11057143 | DOI:10.1186/s12711-024-00903-9 (Source: Genet Sel Evol)
Source: Genet Sel Evol - April 29, 2024 Category: Genetics & Stem Cells Authors: Lucio F M Mota Diana Giannuzzi Sara Pegolo Enrico Sturaro Daniel Gianola Riccardo Negrini Erminio Trevisi Paolo Ajmone Marsan Alessio Cecchinato Source Type: research

Effect of dietary supplementation of plantain herb, lemongrass and their combination on milk yield, immunity, liver enzymes, serum, and milk mineral status in dairy cows
CONCLUSIONS: Both plantain and lemongrass improved dairy cows' DM consumption and milk yield. Plantain and/or lemongrass enhanced the immune system and liver health, but not serum and milk calcium and phosphorus level. Lemongrass and a combination of plantain and lemongrass increased the serum and milk zinc concentrations.PMID:38680813 | PMC:PMC11055577 | DOI:10.5455/javar.2024.k764 (Source: Adv Data)
Source: Adv Data - April 29, 2024 Category: Epidemiology Authors: Md Aliar Rahman Md Rahat Ahmad Redoy Rakhi Chowdhury Mohammad Al-Mamun Source Type: research

Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024
We report highly pathogenic avian influenza A(H5N1) virus in dairy cattle and cats in Kansas and Texas, United States, which reflects the continued spread of clade 2.3.4.4b viruses that entered the country in late 2021. Infected cattle experienced nonspecific illness, reduced feed intake and rumination, and an abrupt drop in milk production, but fatal systemic influenza infection developed in domestic cats fed raw (unpasteurized) colostrum and milk from affected cows. Cow-to-cow transmission appears to have occurred because infections were observed in cattle on Michigan, Idaho, and Ohio farms where avian influenza virus-in...
Source: Emerging Infectious Diseases - April 29, 2024 Category: Infectious Diseases Authors: Eric R Burrough Drew R Magstadt Barbara Petersen Simon J Timmermans Phillip C Gauger Jianqiang Zhang Chris Siepker Marta Mainenti Ganwu Li Alexis C Thompson Patrick J Gorden Paul J Plummer Rodger Main Source Type: research

Genomic prediction of blood biomarkers of metabolic disorders in Holstein cattle using parametric and nonparametric models
CONCLUSIONS: Our results indicate that the Stack approach was more accurate in predicting metabolic disturbances than GBLUP, BayesB, ENET, and GBM and seemed to be competitive for predicting complex phenotypes with various degrees of mode of inheritance, i.e. additive and non-additive effects. Selecting markers based on GBM improved accuracy of GBLUP.PMID:38684971 | PMC:PMC11057143 | DOI:10.1186/s12711-024-00903-9 (Source: Genet Sel Evol)
Source: Genet Sel Evol - April 29, 2024 Category: Genetics & Stem Cells Authors: Lucio F M Mota Diana Giannuzzi Sara Pegolo Enrico Sturaro Daniel Gianola Riccardo Negrini Erminio Trevisi Paolo Ajmone Marsan Alessio Cecchinato Source Type: research

Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024
We report highly pathogenic avian influenza A(H5N1) virus in dairy cattle and cats in Kansas and Texas, United States, which reflects the continued spread of clade 2.3.4.4b viruses that entered the country in late 2021. Infected cattle experienced nonspecific illness, reduced feed intake and rumination, and an abrupt drop in milk production, but fatal systemic influenza infection developed in domestic cats fed raw (unpasteurized) colostrum and milk from affected cows. Cow-to-cow transmission appears to have occurred because infections were observed in cattle on Michigan, Idaho, and Ohio farms where avian influenza virus-in...
Source: Emerging Infectious Diseases - April 29, 2024 Category: Infectious Diseases Authors: Eric R Burrough Drew R Magstadt Barbara Petersen Simon J Timmermans Phillip C Gauger Jianqiang Zhang Chris Siepker Marta Mainenti Ganwu Li Alexis C Thompson Patrick J Gorden Paul J Plummer Rodger Main Source Type: research