Machine learning to identify endometrial biomarkers predictive of pregnancy success following artificial insemination in dairy cows
The objective was to identify a set of genes whose transcript abundance is predictive of a cow's ability to become pregnant following artificial insemination (AI). Endometrial epithelial cells from the uterine body were collected for RNA sequencing using the cytobrush method from 193 first-service Holstein cows at estrus prior to AI (day 0). A group of 253 first-service cows not used for cytobrush collection were controls. There was no effect of cytobrush collection on pregnancy outcomes at day 30 or 70 or on pregnancy loss between day 30 and 70. There were 2 upregulated and 214 downregulated genes (FDR < 0.05, absolute...
Source: Biology of Reproduction - April 9, 2024 Category: Reproduction Medicine Authors: Quinn A Hoorn Maria B Rabaglino Thiago F Amaral Tatiane S Maia Fahong Yu John B Cole Peter J Hansen Source Type: research
Milk and < em > Lacticaseibacillus casei < /em > BL23 effects on intestinal responses in a murine model of colitis
Am J Physiol Gastrointest Liver Physiol. 2024 Apr 9. doi: 10.1152/ajpgi.00259.2023. Online ahead of print.ABSTRACTProbiotic-containing fermented dairy foods have the potential to benefit human health, but the importance of the dairy matrix for efficacy remains unclear. We investigated the capacity of Lacticaseibacillus casei BL23 in phosphate-buffered saline (BL23-PBS), BL23-fermented milk (BL23-milk), and milk to modify intestinal and behavioral responses in a Dextran Sodium Sulfate (DSS, 3% w/v) mouse model of colitis. Significant sex-dependent differences were found such that female mice exhibited more severe colitis, g...
Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - April 9, 2024 Category: Physiology Authors: Glory Bui Cristina Torres-Fuentes Matteo M Pusceddu Melanie G Gareau Maria L Marco Source Type: research
Milk and < em > Lacticaseibacillus casei < /em > BL23 effects on intestinal responses in a murine model of colitis
Am J Physiol Gastrointest Liver Physiol. 2024 Apr 9. doi: 10.1152/ajpgi.00259.2023. Online ahead of print.ABSTRACTProbiotic-containing fermented dairy foods have the potential to benefit human health, but the importance of the dairy matrix for efficacy remains unclear. We investigated the capacity of Lacticaseibacillus casei BL23 in phosphate-buffered saline (BL23-PBS), BL23-fermented milk (BL23-milk), and milk to modify intestinal and behavioral responses in a Dextran Sodium Sulfate (DSS, 3% w/v) mouse model of colitis. Significant sex-dependent differences were found such that female mice exhibited more severe colitis, g...
Source: Am J Physiol Gastroi... - April 9, 2024 Category: Gastroenterology Authors: Glory Bui Cristina Torres-Fuentes Matteo M Pusceddu Melanie G Gareau Maria L Marco Source Type: research
Milk and < em > Lacticaseibacillus casei < /em > BL23 effects on intestinal responses in a murine model of colitis
Am J Physiol Gastrointest Liver Physiol. 2024 Apr 9. doi: 10.1152/ajpgi.00259.2023. Online ahead of print.ABSTRACTProbiotic-containing fermented dairy foods have the potential to benefit human health, but the importance of the dairy matrix for efficacy remains unclear. We investigated the capacity of Lacticaseibacillus casei BL23 in phosphate-buffered saline (BL23-PBS), BL23-fermented milk (BL23-milk), and milk to modify intestinal and behavioral responses in a Dextran Sodium Sulfate (DSS, 3% w/v) mouse model of colitis. Significant sex-dependent differences were found such that female mice exhibited more severe colitis, g...
Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - April 9, 2024 Category: Physiology Authors: Glory Bui Cristina Torres-Fuentes Matteo M Pusceddu Melanie G Gareau Maria L Marco Source Type: research
Milk and < em > Lacticaseibacillus casei < /em > BL23 effects on intestinal responses in a murine model of colitis
Am J Physiol Gastrointest Liver Physiol. 2024 Apr 9. doi: 10.1152/ajpgi.00259.2023. Online ahead of print.ABSTRACTProbiotic-containing fermented dairy foods have the potential to benefit human health, but the importance of the dairy matrix for efficacy remains unclear. We investigated the capacity of Lacticaseibacillus casei BL23 in phosphate-buffered saline (BL23-PBS), BL23-fermented milk (BL23-milk), and milk to modify intestinal and behavioral responses in a Dextran Sodium Sulfate (DSS, 3% w/v) mouse model of colitis. Significant sex-dependent differences were found such that female mice exhibited more severe colitis, g...
Source: Am J Physiol Gastroi... - April 9, 2024 Category: Gastroenterology Authors: Glory Bui Cristina Torres-Fuentes Matteo M Pusceddu Melanie G Gareau Maria L Marco Source Type: research
Milk and < em > Lacticaseibacillus casei < /em > BL23 effects on intestinal responses in a murine model of colitis
Am J Physiol Gastrointest Liver Physiol. 2024 Apr 9. doi: 10.1152/ajpgi.00259.2023. Online ahead of print.ABSTRACTProbiotic-containing fermented dairy foods have the potential to benefit human health, but the importance of the dairy matrix for efficacy remains unclear. We investigated the capacity of Lacticaseibacillus casei BL23 in phosphate-buffered saline (BL23-PBS), BL23-fermented milk (BL23-milk), and milk to modify intestinal and behavioral responses in a Dextran Sodium Sulfate (DSS, 3% w/v) mouse model of colitis. Significant sex-dependent differences were found such that female mice exhibited more severe colitis, g...
Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - April 9, 2024 Category: Physiology Authors: Glory Bui Cristina Torres-Fuentes Matteo M Pusceddu Melanie G Gareau Maria L Marco Source Type: research
Usual intake of dairy products and the chance of pre-diabetes regression to normal glycemia or progression to type 2 diabetes: a 9-year follow-up
Nutrition & Diabetes, Published online: 09 April 2024; doi:10.1038/s41387-024-00257-7Usual intake of dairy products and the chance of pre-diabetes regression to normal glycemia or progression to type 2 diabetes: a 9-year follow-up (Source: Nutrition and Diabetes)
Source: Nutrition and Diabetes - April 9, 2024 Category: Nutrition Authors: Zahra Bahadoran Parvin Mirmiran Fereidoun Azizi Source Type: research
Pyrrolizidine alkaloids and tropane alkaloids in milk samples from individual dairy farms of the German federal states of Bavaria and Schleswig-Holstein
. (Source: Food Additives and Contaminants Part A)
Source: Food Additives and Contaminants Part A - April 9, 2024 Category: Food Science Authors: Lisa Monika KleinJulika LampChristina SchopfAngelika Miriam GablerFlorian KaltnerClaudia GuldimannMichael RychlikChristine Schwake-AnduschusKarin KnappsteinChristoph Gottschalka Chair of Food Safety and Analytics, Faculty of Veterinary Medicine, LMU in Mu Source Type: research
Mendelian randomization analysis of 34,497 German Holstein cows to infer causal associations between milk production and health traits
CONCLUSIONS: Our results confirm the known negative genetic connection between health traits and MY in dairy cattle. In addition, they provide new information about causality, which for example points to the negative energy balance mediating the connection between these traits. This knowledge helps to better understand whether the negative genetic correlation is based on pleiotropy, linkage between causal variants for both trait complexes, or indeed on a causal association.PMID:38589805 | PMC:PMC11000328 | DOI:10.1186/s12711-024-00896-5 (Source: Genet Sel Evol)
Source: Genet Sel Evol - April 8, 2024 Category: Genetics & Stem Cells Authors: Helen Schneider Valentin Haas Ana-Marija Krizanac Clemens Falker-Gieske Johannes Heise Jens Tetens Georg Thaller J örn Bennewitz Source Type: research
Mendelian randomization analysis of 34,497 German Holstein cows to infer causal associations between milk production and health traits
Claw diseases and mastitis represent the most important health issues in dairy cattle with a frequently mentioned connection to milk production. Although many studies have aimed at investigating this connectio... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - April 8, 2024 Category: Genetics & Stem Cells Authors: Helen Schneider, Valentin Haas, Ana-Marija Krizanac, Clemens Falker-Gieske, Johannes Heise, Jens Tetens, Georg Thaller and J örn Bennewitz Tags: Research Article Source Type: research
Turning weeds into feed: Ensiling Calotropis gigantea (Giant milkweed) reduces its toxicity and enhances its palatability for dairy cows
This study aimed to valorize GM as a potential new feed resource through the chemical and microbial biotransformation of toxic compounds that will henceforth, make the plant palatable for cows. After GM's ensiling using fermentative bacteria, the plant was sampled for UHPLC-MS/MS to analyse the metabolomic changes. Illumina Miseq of the 16 S rRNA fragment genes and ITS1 were used to describe the microbial composition and structure colonizing GM silage and contributing to the biodegradation of toxic compounds. Microbial functions were predicted from metataxonomic data and KEGG pathways analysis. Eight Holstein dairy cows as...
Source: Ecotoxicology and Environmental Safety - April 6, 2024 Category: Environmental Health Authors: Aurele Gnetegha Ayemele Yuehu Wang Lu Ma Dengpan Bu Jianchu Xu Source Type: research
Pregnancy losses in Bos indicus-influenced beef and dairy recipients assigned to a fixed-time embryo transfer protocol
Anim Reprod Sci. 2024 Apr 3;264:107471. doi: 10.1016/j.anireprosci.2024.107471. Online ahead of print.ABSTRACTPregnancy losses from fixed-time embryo transfer (FTET) to calving were evaluated in Bos indicus-influenced beef and dairy recipients. Data from 4366 FTET events were collected from Nelore × Angus recipient heifers, and from 38538 FTET events in Gir × Holstein recipient heifers and cows. In beef recipients, pregnancy losses were greater (P < 0.01) from FTET (day 7 of the experiment) to day 32 compared with day 32-100 and with day 100 to calving (58.7, 39.5, and 36.7%, respectively), and did not differ (P = 0.5...
Source: Animal Reproduction Science - April 6, 2024 Category: Zoology Authors: S K Munhoz R F Cooke A K Munhoz C P Prado M H C Pereira J L M Vasconcelos Source Type: research
Turning weeds into feed: Ensiling Calotropis gigantea (Giant milkweed) reduces its toxicity and enhances its palatability for dairy cows
This study aimed to valorize GM as a potential new feed resource through the chemical and microbial biotransformation of toxic compounds that will henceforth, make the plant palatable for cows. After GM's ensiling using fermentative bacteria, the plant was sampled for UHPLC-MS/MS to analyse the metabolomic changes. Illumina Miseq of the 16 S rRNA fragment genes and ITS1 were used to describe the microbial composition and structure colonizing GM silage and contributing to the biodegradation of toxic compounds. Microbial functions were predicted from metataxonomic data and KEGG pathways analysis. Eight Holstein dairy cows as...
Source: Cancer Control - April 6, 2024 Category: Cancer & Oncology Authors: Aurele Gnetegha Ayemele Yuehu Wang Lu Ma Dengpan Bu Jianchu Xu Source Type: research
Turning weeds into feed: Ensiling Calotropis gigantea (Giant milkweed) reduces its toxicity and enhances its palatability for dairy cows
This study aimed to valorize GM as a potential new feed resource through the chemical and microbial biotransformation of toxic compounds that will henceforth, make the plant palatable for cows. After GM's ensiling using fermentative bacteria, the plant was sampled for UHPLC-MS/MS to analyse the metabolomic changes. Illumina Miseq of the 16 S rRNA fragment genes and ITS1 were used to describe the microbial composition and structure colonizing GM silage and contributing to the biodegradation of toxic compounds. Microbial functions were predicted from metataxonomic data and KEGG pathways analysis. Eight Holstein dairy cows as...
Source: Ecotoxicology and Environmental Safety - April 6, 2024 Category: Environmental Health Authors: Aurele Gnetegha Ayemele Yuehu Wang Lu Ma Dengpan Bu Jianchu Xu Source Type: research
Pregnancy losses in Bos indicus-influenced beef and dairy recipients assigned to a fixed-time embryo transfer protocol
Anim Reprod Sci. 2024 Apr 3;264:107471. doi: 10.1016/j.anireprosci.2024.107471. Online ahead of print.ABSTRACTPregnancy losses from fixed-time embryo transfer (FTET) to calving were evaluated in Bos indicus-influenced beef and dairy recipients. Data from 4366 FTET events were collected from Nelore × Angus recipient heifers, and from 38538 FTET events in Gir × Holstein recipient heifers and cows. In beef recipients, pregnancy losses were greater (P < 0.01) from FTET (day 7 of the experiment) to day 32 compared with day 32-100 and with day 100 to calving (58.7, 39.5, and 36.7%, respectively), and did not differ (P = 0.5...
Source: Animal Reproduction Science - April 6, 2024 Category: Zoology Authors: S K Munhoz R F Cooke A K Munhoz C P Prado M H C Pereira J L M Vasconcelos Source Type: research
