Admission rates, Healthcare Utilization, and Inpatient Cost of Radiation Cystitis in the United States
To assess the incidence, cumulative healthcare burden, and financial impact of inpatient admissions for radiation cystitis (RC), while exploring practice differences in RC management between teaching and non-teaching hospitals. (Source: Urology)
Source: Urology - December 29, 2023 Category: Urology & Nephrology Authors: Sohrab Arora, Irene Chen, Chandler Bronkema, Giuseppe Chiarelli, Marco Finati, Giuseppe Cirulli, Sami E. Majdalany, Ivan Rakic, Akshay Sood, Quoc-Dien Trinh, Craig G. Rogers, James O. Peabody, Mani Menon, Firas Abdollah Source Type: research

Molecules, Vol. 29, Pages 189: Pharmacological Properties of Shionone: Potential Anti-Inflammatory Phytochemical against Different Diseases
Lee Shionone is a triterpenoid that is the primary constituent of an important ancient Chinese medicine named Radix Asteris. It has emerged as an attractive candidate against different important diseases, including interstitial cystitis, colitis, cancer, Parkinson’s disease, and urinary tract infections, and was found to have a protective effect on multiple organs, including the colon, kidneys, lungs, brain, and bladder. The anti-inflammation activity of shionone may be considered an important property that imparts the positive health outcomes of shionone. Important molecular targets and markers such as T...
Source: Molecules - December 28, 2023 Category: Chemistry Authors: Varun Jaiswal Hae-Jeung Lee Tags: Review Source Type: research

Obstructive sleep apnea and bladder pain syndrome/interstitial cystitis in women
CONCLUSIONS: The ICSI symptoms and subsequent problems in daily life caused by the symptoms (ICPI) were experienced at a higher rate in patients with OSA than in the control group. There is an association between BPS/IC and OSA.PMID:38147287 | DOI:10.1007/s11325-023-02967-1 (Source: Sleep and Breathing)
Source: Sleep and Breathing - December 26, 2023 Category: Sleep Medicine Authors: İbrahim Güven Çoşğun Abdullah G ürel Source Type: research

Obstructive sleep apnea and bladder pain syndrome/interstitial cystitis in women
CONCLUSIONS: The ICSI symptoms and subsequent problems in daily life caused by the symptoms (ICPI) were experienced at a higher rate in patients with OSA than in the control group. There is an association between BPS/IC and OSA.PMID:38147287 | DOI:10.1007/s11325-023-02967-1 (Source: Sleep and Breathing)
Source: Sleep and Breathing - December 26, 2023 Category: Sleep Medicine Authors: İbrahim Güven Çoşğun Abdullah G ürel Source Type: research

Obstructive sleep apnea and bladder pain syndrome/interstitial cystitis in women
ConclusionsThe ICSI symptoms and subsequent problems in daily life caused by the symptoms (ICPI) were experienced at a higher rate in patients with  OSA than in the control group. There is an association between BPS/IC and OSA. (Source: Sleep and Breathing)
Source: Sleep and Breathing - December 26, 2023 Category: Respiratory Medicine Source Type: research

Antibiotic Use in Hospital Urinary Tract Infections After FDA Regulation
ConclusionsDuring this era of “black box” warnings, there was a decline in fluoroquinolone use for hospital-treated UTI with a concomitant decline in fluoroquinolone resistance and rise in ceftriaxone use. Efforts to restrict use of a medication class may lead to compensatory increases in use of a single alternative agent wi th changes in antimicrobial resistance profiles. (Source: Journal of General Internal Medicine)
Source: Journal of General Internal Medicine - December 26, 2023 Category: Internal Medicine Source Type: research

Obstructive sleep apnea and bladder pain syndrome/interstitial cystitis in women
ConclusionsThe ICSI symptoms and subsequent problems in daily life caused by the symptoms (ICPI) were experienced at a higher rate in patients with  OSA than in the control group. There is an association between BPS/IC and OSA. (Source: Sleep and Breathing)
Source: Sleep and Breathing - December 26, 2023 Category: Respiratory Medicine Source Type: research

Bladder instillation patterns in a cohort of women with interstitial cystitis/bladder pain syndrome
CONCLUSIONS: In our cohort, few women with IC/BPS received a recommended treatment course of six weekly instillations, with most receiving only one per course. Future studies are needed to determine if instillation courses were altered from the guideline due to provider practice patterns, early improvement, or poor tolerance of instillations.PMID:38107872 | PMC:PMC10723800 | DOI:10.1097/spv.0000000000001369 (Source: Cancer Control)
Source: Cancer Control - December 18, 2023 Category: Cancer & Oncology Authors: Clarissa A Niino Lauren N Tholemeier Catherine Bresee Amanda M De Hoedt Kamil E Barbour Jayoung Kim Stephen J Freedland Jennifer T Anger Source Type: research

Recurring cystitis cystica and cystitis glandularis masquerading as urothelial carcinoma
We report a rare case of cystitis cystica and glandularis mimicking low-grade urothelial carcinoma that was found incidentally and treated with resection and fulguration via transurethral resection of bladder tumor (TURBT). When early recurrence was found on surveillance cystoscopy 3 months later, the patient was treated with repeat TURBT and intravesical gemcitabine. Surveillance cystoscopy 4 months later revealed cystitis cystica and cystitis glandularis yet again. We highlight the diagnosis and management of multiple early recurrences of cystitis cystica in this patient, particularly our treatment with gemcitabine and c...
Source: Canadian Journal of Urology - December 17, 2023 Category: Urology & Nephrology Authors: Kerith R Wang Rishabh K Simhal Gabriel G Dinatale Li Li Thenappan Chandrasekar Source Type: research

Re: Pentosan polysulfate and a pigmentary maculopathy: causation versus correlation?
Can J Urol. 2023 Dec;30(6):11740.ABSTRACTHow should a conscientious physician advise patients with Interstitial Cystitis /Bladder Pain Syndrome (IC/BPS) when they want to know if taking Pentosan Polysulfate Sodium (PPS) will lead to loss of vision? Ever since the initial report from Pearce et al in 2018 suggesting that PPS usage can lead to the development of pigmented maculopathy (PM), my patients have been inundated with solicitations from attorneys looking to sign up clients for class action lawsuits.1 While there have been additional reports suggesting a relationship between PPS exposure and the development of PM, Ludw...
Source: Canadian Journal of Urology - December 17, 2023 Category: Urology & Nephrology Authors: Robert J Evans Raymond Xu Source Type: research

Pentosan polysulfate and a pigmentary maculopathy: causation versus correlation?
CONCLUSIONS: After an analysis of the literature describing a pigmentary maculopathy in IC patients on long term PPS, a causal relationship does not appear to be present. An alternate model is proposed postulating that the causative factor for the pigmentary maculopathy is the underlying inflammatory state associated with IC and not PPS use.PMID:38104330 (Source: Canadian Journal of Urology)
Source: Canadian Journal of Urology - December 17, 2023 Category: Urology & Nephrology Authors: Jeffrey G Proctor Source Type: research

Re: Pentosan polysulfate and a pigmentary maculopathy: causation versus correlation?
Can J Urol. 2023 Dec;30(6):11740.ABSTRACTHow should a conscientious physician advise patients with Interstitial Cystitis /Bladder Pain Syndrome (IC/BPS) when they want to know if taking Pentosan Polysulfate Sodium (PPS) will lead to loss of vision? Ever since the initial report from Pearce et al in 2018 suggesting that PPS usage can lead to the development of pigmented maculopathy (PM), my patients have been inundated with solicitations from attorneys looking to sign up clients for class action lawsuits.1 While there have been additional reports suggesting a relationship between PPS exposure and the development of PM, Ludw...
Source: Pain Physician - December 17, 2023 Category: Anesthesiology Authors: Robert J Evans Raymond Xu Source Type: research

Pentosan polysulfate and a pigmentary maculopathy: causation versus correlation?
CONCLUSIONS: After an analysis of the literature describing a pigmentary maculopathy in IC patients on long term PPS, a causal relationship does not appear to be present. An alternate model is proposed postulating that the causative factor for the pigmentary maculopathy is the underlying inflammatory state associated with IC and not PPS use.PMID:38104330 (Source: Canadian Journal of Urology)
Source: Canadian Journal of Urology - December 17, 2023 Category: Urology & Nephrology Authors: Jeffrey G Proctor Source Type: research

Re: Pentosan polysulfate and a pigmentary maculopathy: causation versus correlation?
Can J Urol. 2023 Dec;30(6):11740.ABSTRACTHow should a conscientious physician advise patients with Interstitial Cystitis /Bladder Pain Syndrome (IC/BPS) when they want to know if taking Pentosan Polysulfate Sodium (PPS) will lead to loss of vision? Ever since the initial report from Pearce et al in 2018 suggesting that PPS usage can lead to the development of pigmented maculopathy (PM), my patients have been inundated with solicitations from attorneys looking to sign up clients for class action lawsuits.1 While there have been additional reports suggesting a relationship between PPS exposure and the development of PM, Ludw...
Source: Canadian Journal of Urology - December 17, 2023 Category: Urology & Nephrology Authors: Robert J Evans Raymond Xu Source Type: research

Recurring cystitis cystica and cystitis glandularis masquerading as urothelial carcinoma
We report a rare case of cystitis cystica and glandularis mimicking low-grade urothelial carcinoma that was found incidentally and treated with resection and fulguration via transurethral resection of bladder tumor (TURBT). When early recurrence was found on surveillance cystoscopy 3 months later, the patient was treated with repeat TURBT and intravesical gemcitabine. Surveillance cystoscopy 4 months later revealed cystitis cystica and cystitis glandularis yet again. We highlight the diagnosis and management of multiple early recurrences of cystitis cystica in this patient, particularly our treatment with gemcitabine and c...
Source: Canadian Journal of Urology - December 17, 2023 Category: Urology & Nephrology Authors: Kerith R Wang Rishabh K Simhal Gabriel G Dinatale Li Li Thenappan Chandrasekar Source Type: research