Research progress on drug resistance of anti-varicella-zoster virus drugs
Zhonghua Yu Fang Yi Xue Za Zhi. 2023 Feb 6;57(2):259-267. doi: 10.3760/cma.j.cn112150-20220825-00839.ABSTRACTVaricella-zoster virus (VZV) causes chickenpox when it first infects humans, and the virus may reactivate in adulthood and cause herpes zoster (HZ). Broad-spectrum antiviral drugs are one of the treatments for varicella and herpes zoster, but the emergence of drug resistance poses many challenges to this treatment and increases the burden of disease on patients. This paper discusses the resistance mechanisms, resistance sites and resistance detection methods of anti-VZV drugs in order to help further research on new...
Source: Herpes - February 16, 2023 Category: Infectious Diseases Authors: Y L Zhang W Z Su C F Ma S T Xu Source Type: research

Parental acceptance of and preferences for administration of routine varicella vaccination in the UK: A study to inform policy
CONCLUSIONS: Most parents would accept a varicella vaccination. These findings highlight parents' preferences for varicella vaccine administration, information needed to inform vaccine policy and practice and development of a communication strategy.PMID:36796935 | DOI:10.1016/j.vaccine.2023.01.027 (Source: Vaccine)
Source: Vaccine - February 16, 2023 Category: Allergy & Immunology Authors: Susan M Sherman Nicola Lingley-Heath Jasmine Lai Julius Sim Helen Bedford Source Type: research

Research progress on drug resistance of anti-varicella-zoster virus drugs
Zhonghua Yu Fang Yi Xue Za Zhi. 2023 Feb 6;57(2):259-267. doi: 10.3760/cma.j.cn112150-20220825-00839.ABSTRACTVaricella-zoster virus (VZV) causes chickenpox when it first infects humans, and the virus may reactivate in adulthood and cause herpes zoster (HZ). Broad-spectrum antiviral drugs are one of the treatments for varicella and herpes zoster, but the emergence of drug resistance poses many challenges to this treatment and increases the burden of disease on patients. This paper discusses the resistance mechanisms, resistance sites and resistance detection methods of anti-VZV drugs in order to help further research on new...
Source: Herpes - February 16, 2023 Category: Infectious Diseases Authors: Y L Zhang W Z Su C F Ma S T Xu Source Type: research

Parental acceptance of and preferences for administration of routine varicella vaccination in the UK: A study to inform policy
CONCLUSIONS: Most parents would accept a varicella vaccination. These findings highlight parents' preferences for varicella vaccine administration, information needed to inform vaccine policy and practice and development of a communication strategy.PMID:36796935 | DOI:10.1016/j.vaccine.2023.01.027 (Source: Vaccine)
Source: Vaccine - February 16, 2023 Category: Allergy & Immunology Authors: Susan M Sherman Nicola Lingley-Heath Jasmine Lai Julius Sim Helen Bedford Source Type: research

Parental acceptance of and preferences for administration of routine varicella vaccination in the UK: A study to inform policy
CONCLUSIONS: Most parents would accept a varicella vaccination. These findings highlight parents' preferences for varicella vaccine administration, information needed to inform vaccine policy and practice and development of a communication strategy.PMID:36796935 | DOI:10.1016/j.vaccine.2023.01.027 (Source: Vaccine)
Source: Vaccine - February 16, 2023 Category: Allergy & Immunology Authors: Susan M Sherman Nicola Lingley-Heath Jasmine Lai Julius Sim Helen Bedford Source Type: research

Parental acceptance of and preferences for administration of routine varicella vaccination in the UK: A study to inform policy
CONCLUSIONS: Most parents would accept a varicella vaccination. These findings highlight parents' preferences for varicella vaccine administration, information needed to inform vaccine policy and practice and development of a communication strategy.PMID:36796935 | DOI:10.1016/j.vaccine.2023.01.027 (Source: Vaccine)
Source: Vaccine - February 16, 2023 Category: Allergy & Immunology Authors: Susan M Sherman Nicola Lingley-Heath Jasmine Lai Julius Sim Helen Bedford Source Type: research

Viruses, Vol. 15, Pages 439: Herpes Simplex Virus and Varicella Zoster Virus Infections in Cancer Patients
Ho Herpes simplex virus (HSV) and varicella zoster virus (VZV) are alpha herpesviruses that establish life-long latent infection in neuronal ganglia after primary infection. Periodic reactivation of these viruses results in recurrent infections that can have significant impact on patients’ quality of life. HSV commonly causes oral and genital mucocutaneous infections whereas VZV is responsible for varicella/chickenpox and herpes zoster/shingles, but cancer patients are at particularly higher risk of complications including disseminated and visceral infections due to impaired cell-mediated immunity. While...
Source: Viruses - February 5, 2023 Category: Virology Authors: Ralph Tayyar Dora Ho Tags: Review Source Type: research

Vaccine hesitancy among Ukrainian refugees
ConclusionsThe efforts made to ensure complete care and promote vaccination among refugees, offering them a complete evaluation of the vaccination status and the possibility of being vaccinated for free, seem to be insufficient to convince most refugees to get vaccinated. (Source: Journal of Preventive Medicine and Hygiene)
Source: Journal of Preventive Medicine and Hygiene - February 3, 2023 Category: International Medicine & Public Health Authors: Gianmarco Troiano, Giuseppe Torchia, Alessandra Nardi Source Type: research

Rapid, sensitive, and specific lateral-flow immunochromatographic point-of-care device for detection of varicella-zoster virus immunoglobulin G antibodies in fingerstick blood
J Immunol Methods. 2023 Jan 20:113429. doi: 10.1016/j.jim.2023.113429. Online ahead of print.ABSTRACTVaricella zoster virus (VZV) causes childhood chickenpox, becomes latent in sensory ganglia and reactivates years later to cause shingles (Zoster) and postherpetic neuralgia in the elderly and immunosuppressed individuals. Serologic IgG tests can be used to determine if a person has antibodies to VZV from past varicella infection or had received varicella or zoster (shingles) vaccination. Commercial enzyme-linked immunosorbent assays (ELISAs) are currently used for the detection of VZV IgG antibodies in patient serum sample...
Source: Journal of Immunological Methods - January 23, 2023 Category: Allergy & Immunology Authors: Nicholas Vafai Kevin Self Bret Sheffield Sally Hojvat Aubrey Kusi-Appiah Patrick Vaughan Elliot Cowan Abbas Vafai Source Type: research

Rapid, sensitive, and specific lateral-flow immunochromatographic point-of-care device for detection of varicella-zoster virus immunoglobulin G antibodies in fingerstick blood
J Immunol Methods. 2023 Jan 20:113429. doi: 10.1016/j.jim.2023.113429. Online ahead of print.ABSTRACTVaricella zoster virus (VZV) causes childhood chickenpox, becomes latent in sensory ganglia and reactivates years later to cause shingles (Zoster) and postherpetic neuralgia in the elderly and immunosuppressed individuals. Serologic IgG tests can be used to determine if a person has antibodies to VZV from past varicella infection or had received varicella or zoster (shingles) vaccination. Commercial enzyme-linked immunosorbent assays (ELISAs) are currently used for the detection of VZV IgG antibodies in patient serum sample...
Source: Journal of Immunological Methods - January 23, 2023 Category: Allergy & Immunology Authors: Nicholas Vafai Kevin Self Bret Sheffield Sally Hojvat Aubrey Kusi-Appiah Patrick Vaughan Elliot Cowan Abbas Vafai Source Type: research

Rapid, sensitive, and specific lateral-flow immunochromatographic point-of-care device for detection of varicella-zoster virus immunoglobulin G antibodies in fingerstick blood
J Immunol Methods. 2023 Jan 20:113429. doi: 10.1016/j.jim.2023.113429. Online ahead of print.ABSTRACTVaricella zoster virus (VZV) causes childhood chickenpox, becomes latent in sensory ganglia and reactivates years later to cause shingles (Zoster) and postherpetic neuralgia in the elderly and immunosuppressed individuals. Serologic IgG tests can be used to determine if a person has antibodies to VZV from past varicella infection or had received varicella or zoster (shingles) vaccination. Commercial enzyme-linked immunosorbent assays (ELISAs) are currently used for the detection of VZV IgG antibodies in patient serum sample...
Source: Journal of Immunological Methods - January 23, 2023 Category: Allergy & Immunology Authors: Nicholas Vafai Kevin Self Bret Sheffield Sally Hojvat Aubrey Kusi-Appiah Patrick Vaughan Elliot Cowan Abbas Vafai Source Type: research

Rapid, sensitive, and specific lateral-flow immunochromatographic point-of-care device for detection of varicella-zoster virus immunoglobulin G antibodies in fingerstick blood
J Immunol Methods. 2023 Jan 21;514:113429. doi: 10.1016/j.jim.2023.113429. Online ahead of print.ABSTRACTVaricella zoster virus (VZV) causes childhood chickenpox, becomes latent in sensory ganglia and reactivates years later to cause shingles (Zoster) and postherpetic neuralgia in the elderly and immunosuppressed individuals. Serologic IgG tests can be used to determine if a person has antibodies to VZV from past varicella infection or had received varicella or zoster (shingles) vaccination. Commercial enzyme-linked immunosorbent assays (ELISAs) are currently used for the detection of VZV IgG antibodies in patient serum sa...
Source: Journal of Immunological Methods - January 23, 2023 Category: Allergy & Immunology Authors: Nicholas Vafai Kevin Self Bret Sheffield Sally Hojvat Aubrey Kusi-Appiah Patrick Vaughan Elliot Cowan Abbas Vafai Source Type: research

Rapid, sensitive, and specific lateral-flow immunochromatographic point-of-care device for detection of varicella-zoster virus immunoglobulin G antibodies in fingerstick blood
J Immunol Methods. 2023 Jan 21;514:113429. doi: 10.1016/j.jim.2023.113429. Online ahead of print.ABSTRACTVaricella zoster virus (VZV) causes childhood chickenpox, becomes latent in sensory ganglia and reactivates years later to cause shingles (Zoster) and postherpetic neuralgia in the elderly and immunosuppressed individuals. Serologic IgG tests can be used to determine if a person has antibodies to VZV from past varicella infection or had received varicella or zoster (shingles) vaccination. Commercial enzyme-linked immunosorbent assays (ELISAs) are currently used for the detection of VZV IgG antibodies in patient serum sa...
Source: Journal of Immunological Methods - January 23, 2023 Category: Allergy & Immunology Authors: Nicholas Vafai Kevin Self Bret Sheffield Sally Hojvat Aubrey Kusi-Appiah Patrick Vaughan Elliot Cowan Abbas Vafai Source Type: research