Rapid, sensitive, and specific lateral-flow immunochromatographic point-of-care device for detection of varicella-zoster virus immunoglobulin G antibodies in fingerstick blood
J Immunol Methods. 2023 Jan 21;514:113429. doi: 10.1016/j.jim.2023.113429. Online ahead of print.ABSTRACTVaricella zoster virus (VZV) causes childhood chickenpox, becomes latent in sensory ganglia and reactivates years later to cause shingles (Zoster) and postherpetic neuralgia in the elderly and immunosuppressed individuals. Serologic IgG tests can be used to determine if a person has antibodies to VZV from past varicella infection or had received varicella or zoster (shingles) vaccination. Commercial enzyme-linked immunosorbent assays (ELISAs) are currently used for the detection of VZV IgG antibodies in patient serum sa...
Source: Journal of Immunological Methods - January 23, 2023 Category: Allergy & Immunology Authors: Nicholas Vafai Kevin Self Bret Sheffield Sally Hojvat Aubrey Kusi-Appiah Patrick Vaughan Elliot Cowan Abbas Vafai Source Type: research
Trends in varicella epidemiology among an unvaccinated population: first results from Libya
Varicella-zoster virus (VZV) is a highly infectious virus that causes varicella (chickenpox). The global numbers of incident and death cases due to VZV infection were 83 963 744 and 14 553, respectively.1 Most infections occur during childhood; however, in 10% to 20% of the cases, the virus remains latent in neural ganglia and can reactivate later, causing herpes zoster (shingles) in older age groups and immunocompromised people.2 The infection is transmitted from person to person mainly by inhaling aerosols of the respiratory tract secretions from the infected people. The VZV infection can be transmitted by direct contact...
Source: Archives of Disease in Childhood - January 19, 2023 Category: Pediatrics Authors: Ismail, F., Haq, S. Tags: PostScript Source Type: research
Investigation of susceptibility genes for chickenpox disease across multiple continents
Biochem Biophys Rep. 2022 Dec 31;33:101419. doi: 10.1016/j.bbrep.2022.101419. eCollection 2023 Mar.ABSTRACTChickenpox (varicella) is caused by infection with the varicella-zoster virus (VZV), a neurotropic alpha herpes virus with a double-stranded DNA genome. Chickenpox can cause life-threatening complications, including subsequent bacterial infections, central nervous system symptoms, and even death without any risk factors. Few studies have been reported to investigate genetic susceptibility implicated in chickenpox. Herein, our study identified global genetic variants that potentially contributed to chickenpox susceptib...
Source: Herpes - January 9, 2023 Category: Infectious Diseases Authors: Lalu Muhammad Irham Wirawan Adikusuma Lolita Lolita Anisa Nova Puspitaningrum Arief Rahman Afief Made Ary Sarasmita Haafizah Dania Sabiah Khairi Gina Noor Djalilah Barkah Djaka Purwanto Rocky Cheung Source Type: research
Investigation of susceptibility genes for chickenpox disease across multiple continents
Biochem Biophys Rep. 2022 Dec 31;33:101419. doi: 10.1016/j.bbrep.2022.101419. eCollection 2023 Mar.ABSTRACTChickenpox (varicella) is caused by infection with the varicella-zoster virus (VZV), a neurotropic alpha herpes virus with a double-stranded DNA genome. Chickenpox can cause life-threatening complications, including subsequent bacterial infections, central nervous system symptoms, and even death without any risk factors. Few studies have been reported to investigate genetic susceptibility implicated in chickenpox. Herein, our study identified global genetic variants that potentially contributed to chickenpox susceptib...
Source: Herpes - January 9, 2023 Category: Infectious Diseases Authors: Lalu Muhammad Irham Wirawan Adikusuma Lolita Lolita Anisa Nova Puspitaningrum Arief Rahman Afief Made Ary Sarasmita Haafizah Dania Sabiah Khairi Gina Noor Djalilah Barkah Djaka Purwanto Rocky Cheung Source Type: research
Sensors, Vol. 23, Pages 676: Emerging Methods in Biosensing of Immunoglobin G & mdash;A Review
Sensors, Vol. 23, Pages 676: Emerging Methods in Biosensing of Immunoglobin G—A Review
Sensors doi: 10.3390/s23020676
Authors:
Tehmina Azam
Syed Hassan Bukhari
Usman Liaqat
Waheed Miran
Human antibodies are produced due to the activation of immune system components upon exposure to an external agent or antigen. Human antibody G, or immunoglobin G (IgG), accounts for 75% of total serum antibody content. IgG controls several infections by eradicating disease-causing pathogens from the body through complementary interactions with toxins. Additionally, IgG is an important diagnostic tool for certain pat...
Source: Sensors - January 6, 2023 Category: Biotechnology Authors: Tehmina Azam Syed Hassan Bukhari Usman Liaqat Waheed Miran Tags: Review Source Type: research
Monkeypox: Epidemiological surveillance in the Mu ñiz Outpatient Monitoring Unit, Buenos Aires
CONCLUSIONS: The first symptoms began two to five days prior to consultation, the most frequent being fever, myalgia, asthenia, headache, and painful lymphadenopathy. Epidemiological surveillance of SV provides timely detection of cases, continuous and systematic follow-up of contacts through an integrated process between surveillance and laboratory, to generate timely, valid and reliable information, which allows guiding prevention and control measures.PMID:36571518 (Source: Herpes)
Source: Herpes - December 26, 2022 Category: Infectious Diseases Authors: Javier S ánchez Doncell Carina A Sotelo Ignacio Braga Jos é L Francos M ónica Romano Pablo Gonzalez Montaner Source Type: research
Blistering exanthems in the times of monkeypox —Keep calm and do not panic!
To the Editor: In the current outbreak of monkeypox, infectious disease specialists and dermatologists are flooded with numerous consults every day, asking- “could this be monkeypox?” While eruptive rashes of viral maculopapular exanthems, vasculitis, and erythema multiforme can be usually differentiated, chickenpox and 2 other entities with seasonal, sporadic, and periodic outbreak clusters in schools, families, or localities—hand, foot, and mout h disease (HFMD) and papular acrodermatitis/Gianotti-Crosti syndrome (GCS) are at times difficult to differentiate from monkeypox. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - December 24, 2022 Category: Dermatology Authors: Nikhil Mehta, Somesh Gupta Tags: JAAD Online Source Type: research
Prevention of Herpes Zoster: A Focus on the Effectiveness and Safety of Herpes Zoster Vaccines
Viruses. 2022 Nov 29;14(12):2667. doi: 10.3390/v14122667.ABSTRACTInfection with varicella zoster virus typically occurs in children and it can cause primary varicella infection or "chickenpox", or it can reactivate later in life and cause herpes zoster or "shingles". Herpes zoster mainly occurs in older adults, causing a reduction in activities of daily living, impacting quality of life, and may lead to serious complications, including chronic pain. Two vaccines are marketed to prevent herpes zoster: the live zoster vaccine and the non-live, recombinant zoster vaccine. The pre-licensure clinical trials show the efficacy of...
Source: Herpes - December 23, 2022 Category: Infectious Diseases Authors: Yasmin Marra Fawziah Lalji Source Type: research
Rapid Detection of the Varicella-Zoster Virus Using a Recombinase-Aided Amplification-Lateral Flow System
Diagnostics (Basel). 2022 Nov 25;12(12):2957. doi: 10.3390/diagnostics12122957.ABSTRACTVaricella-zoster virus (VZV) is the etiological agent of varicella (chickenpox) and herpes zoster (shingles). VZV infections are ubiquitous and highly contagious, and diagnosis is mostly based on the assessment of signs and symptoms. However, monkeypox, an emerging infectious disease caused by the monkeypox virus (MPXV), has clinical manifestations that are similar to those of VZV infections. With the recent monkeypox outbreak in non-endemic regions, VZV infections are likely to be misdiagnosed in the absence of laboratory testing. Consi...
Source: Herpes - December 23, 2022 Category: Infectious Diseases Authors: Kathrina Mae Bienes Lingjing Mao Benjamin Selekon Ella Gonofio Emmanuel Nakoune Gary Wong Nicolas Berthet Source Type: research
Prevention of Herpes Zoster: A Focus on the Effectiveness and Safety of Herpes Zoster Vaccines
Viruses. 2022 Nov 29;14(12):2667. doi: 10.3390/v14122667.ABSTRACTInfection with varicella zoster virus typically occurs in children and it can cause primary varicella infection or "chickenpox", or it can reactivate later in life and cause herpes zoster or "shingles". Herpes zoster mainly occurs in older adults, causing a reduction in activities of daily living, impacting quality of life, and may lead to serious complications, including chronic pain. Two vaccines are marketed to prevent herpes zoster: the live zoster vaccine and the non-live, recombinant zoster vaccine. The pre-licensure clinical trials show the efficacy of...
Source: Herpes - December 23, 2022 Category: Infectious Diseases Authors: Yasmin Marra Fawziah Lalji Source Type: research
Rapid Detection of the Varicella-Zoster Virus Using a Recombinase-Aided Amplification-Lateral Flow System
Diagnostics (Basel). 2022 Nov 25;12(12):2957. doi: 10.3390/diagnostics12122957.ABSTRACTVaricella-zoster virus (VZV) is the etiological agent of varicella (chickenpox) and herpes zoster (shingles). VZV infections are ubiquitous and highly contagious, and diagnosis is mostly based on the assessment of signs and symptoms. However, monkeypox, an emerging infectious disease caused by the monkeypox virus (MPXV), has clinical manifestations that are similar to those of VZV infections. With the recent monkeypox outbreak in non-endemic regions, VZV infections are likely to be misdiagnosed in the absence of laboratory testing. Consi...
Source: Herpes - December 23, 2022 Category: Infectious Diseases Authors: Kathrina Mae Bienes Lingjing Mao Benjamin Selekon Ella Gonofio Emmanuel Nakoune Gary Wong Nicolas Berthet Source Type: research
When a neglected tropical disease goes global: early estimates from the Monkeypox outbreak, the first 1,054 cases
Acta Biomed. 2022 Dec 16;93(6):e2022330. doi: 10.23750/abm.v93i6.13306.ABSTRACTMonkeypox virus (MPXV), genus Orthopoxvirus, is a large double-stranded DNA virus (200-250 nm), that is evolutionarily related to human variola virus (VARV) (1), and causes a clinical syndrome quite similar to smallpox, with a generally less severe outcome (1,2). MPXV has a wide range of hosts and reservoirs in wild animals, and since 1970 has been commonly acknowledged as a human pathogen, endemic to Central and Western African countries through two distinctive clades (2,3). Central African clade (CAC) is responsible of the majority of 20,000 i...
Source: Acta Bio-Medica : Atenei Parmensis - December 19, 2022 Category: General Medicine Authors: Matteo Ricc ò Source Type: research
When a neglected tropical disease goes global: early estimates from the Monkeypox outbreak, the first 1,054 cases
Acta Biomed. 2022 Dec 16;93(6):e2022330. doi: 10.23750/abm.v93i6.13306.ABSTRACTMonkeypox virus (MPXV), genus Orthopoxvirus, is a large double-stranded DNA virus (200-250 nm), that is evolutionarily related to human variola virus (VARV) (1), and causes a clinical syndrome quite similar to smallpox, with a generally less severe outcome (1,2). MPXV has a wide range of hosts and reservoirs in wild animals, and since 1970 has been commonly acknowledged as a human pathogen, endemic to Central and Western African countries through two distinctive clades (2,3). Central African clade (CAC) is responsible of the majority of 20,000 i...
Source: Acta Bio-Medica : Atenei Parmensis - December 19, 2022 Category: General Medicine Authors: Matteo Ricc ò Source Type: research
When a neglected tropical disease goes global: early estimates from the Monkeypox outbreak, the first 1,054 cases
Acta Biomed. 2022 Dec 16;93(6):e2022330. doi: 10.23750/abm.v93i6.13306.ABSTRACTMonkeypox virus (MPXV), genus Orthopoxvirus, is a large double-stranded DNA virus (200-250 nm), that is evolutionarily related to human variola virus (VARV) (1), and causes a clinical syndrome quite similar to smallpox, with a generally less severe outcome (1,2). MPXV has a wide range of hosts and reservoirs in wild animals, and since 1970 has been commonly acknowledged as a human pathogen, endemic to Central and Western African countries through two distinctive clades (2,3). Central African clade (CAC) is responsible of the majority of 20,000 i...
Source: Acta Bio-Medica : Atenei Parmensis - December 19, 2022 Category: General Medicine Authors: Matteo Ricc ò Source Type: research
When a neglected tropical disease goes global: early estimates from the Monkeypox outbreak, the first 1,054 cases
Acta Biomed. 2022 Dec 16;93(6):e2022330. doi: 10.23750/abm.v93i6.13306.ABSTRACTMonkeypox virus (MPXV), genus Orthopoxvirus, is a large double-stranded DNA virus (200-250 nm), that is evolutionarily related to human variola virus (VARV) (1), and causes a clinical syndrome quite similar to smallpox, with a generally less severe outcome (1,2). MPXV has a wide range of hosts and reservoirs in wild animals, and since 1970 has been commonly acknowledged as a human pathogen, endemic to Central and Western African countries through two distinctive clades (2,3). Central African clade (CAC) is responsible of the majority of 20,000 i...
Source: Acta Bio-Medica : Atenei Parmensis - December 19, 2022 Category: General Medicine Authors: Matteo Ricc ò Source Type: research
