Trends in varicella epidemiology among an unvaccinated population: first results from Libya

Varicella-zoster virus (VZV) is a highly infectious virus that causes varicella (chickenpox). The global numbers of incident and death cases due to VZV infection were 83 963 744 and 14 553, respectively.1 Most infections occur during childhood; however, in 10% to 20% of the cases, the virus remains latent in neural ganglia and can reactivate later, causing herpes zoster (shingles) in older age groups and immunocompromised people.2 The infection is transmitted from person to person mainly by inhaling aerosols of the respiratory tract secretions from the infected people. The VZV infection can be transmitted by direct contact with the upper respiratory tract and mucus membrane of the conjunctiva and the contaminated fluids of skin lesions of the infected persons and the infection usually develop into clinical disease in susceptible individuals.3 The disease is characterised by pruritic, maculopapular, vesicular rashes that progress into non-infectious dry crusts over...
Source: Archives of Disease in Childhood - Category: Pediatrics Authors: Tags: PostScript Source Type: research