Augmenting varenicline treatment with transcranial direct current stimulation (tDCS) increases smoking abstinence rates at end of treatment
Tobacco smoking relapse is often associated with neuroadaptations such as desensitization of nicotine acetylcholine receptors [1]. Varenicline, an α4β2 nicotinic acetylcholine receptor partial agonist, is currently the most effective pharmacotherapy for smoking cessation, however, long-term abstinence rates remain low [2]. Given the emphasis of neuroplasticity in chronic tobacco use, the adjunctive use of neuromodulation techniques such as t ranscranial direct current stimulation (tDCS) can potentially target and reverse select neuroadaptations associated with tobacco smoking relapse. (Source: BRAIN STIMULATION: Basic, T...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 3, 2023 Category: Neurology Authors: Helena Zhang, Tarek K. Rajji, Peter Selby, Osnat Melamed, Sophia Attwells, Laurie Zawertailo Source Type: research

Management of nicotine dependence in patients with psychiatric disorders - recommendations of the Polish Psychiatric Association - part II
Psychiatr Pol. 2023 May 5:1-13. doi: 10.12740/PP/OnlineFirst/161774. Online ahead of print.ABSTRACTThe development of treatment methods for nicotine dependence has progressed slowly because people with psychiatric disorders are usually excluded from participating in clinical trials. There are several therapeutic options to support smoking cessation, including psychological and pharmacological interventions, which should be offered to smokers with mental disorders. The first step in helping tobacco smokers and nicotine-dependent individuals is the assessment of smoking intensity and confirmation of nicotine dependence. Curr...
Source: Psychiatria Polska - June 28, 2023 Category: Psychiatry Authors: Marcin Wojnar Piotr Wierzbi ński Jerzy Samochowiec Joanna Rymaszewska Krzysztof J Filipiak Adam Wichniak Robert Mr óz Artur Mamcarz Dominika Dudek Source Type: research

Initiation of Varenicline in People Hospitalized for Acute Coronary Syndrome Who Smoke
Circulation. 2023 Jun 20;147(25):1869-1871. doi: 10.1161/CIRCULATIONAHA.123.064257. Epub 2023 Jun 19.NO ABSTRACTPMID:37335826 | DOI:10.1161/CIRCULATIONAHA.123.064257 (Source: Circulation)
Source: Circulation - June 19, 2023 Category: Cardiology Authors: Areesha Moiz Mark J Eisenberg Source Type: research

Initiation of Varenicline in People Hospitalized for Acute Coronary Syndrome Who Smoke
Circulation. 2023 Jun 20;147(25):1869-1871. doi: 10.1161/CIRCULATIONAHA.123.064257. Epub 2023 Jun 19.NO ABSTRACTPMID:37335826 | DOI:10.1161/CIRCULATIONAHA.123.064257 (Source: Circulation)
Source: Circulation - June 19, 2023 Category: Cardiology Authors: Areesha Moiz Mark J Eisenberg Source Type: research

Comparative effect of varenicline and nicotine patches on preventing repeat cardiovascular events
Conclusion We found no difference between varenicline and prescription NRT patches in the risk of recurrent MACE. These results should be considered when determining the most appropriate choice of smoking cessation pharmacotherapy. (Source: Heart)
Source: Heart - June 14, 2023 Category: Cardiology Authors: Robijn, A. L., Filion, K. B., Woodward, M., Hsu, B., Chow, C. K., Pearson, S.-A., Jorm, L., Falster, M. O., Havard, A. Tags: Cardiac risk factors and prevention Source Type: research

Interventions for waterpipe smoking cessation
CONCLUSIONS: We found low-certainty evidence that behavioral waterpipe cessation interventions can increase waterpipe quit rates among waterpipe smokers. We found insufficient evidence to assess whether varenicline or bupropion increased waterpipe abstinence; available evidence is compatible with effect sizes similar to those seen for cigarette smoking cessation. Given e-health interventions' potential reach and effectiveness for waterpipe cessation, trials with large samples and long follow-up periods are needed. Future studies should use biochemical validation of abstinence to prevent the risk of detection bias. Finally,...
Source: Cochrane Database of Systematic Reviews - June 7, 2023 Category: General Medicine Authors: Taghrid Asfar Jonathan Livingstone-Banks Kenneth D Ward Thomas Eissenberg Olusanya Oluwole Zoran Bursac Tarek Ghaddar Wasim Maziak Source Type: research

Interventions for waterpipe smoking cessation
CONCLUSIONS: We found low-certainty evidence that behavioral waterpipe cessation interventions can increase waterpipe quit rates among waterpipe smokers. We found insufficient evidence to assess whether varenicline or bupropion increased waterpipe abstinence; available evidence is compatible with effect sizes similar to those seen for cigarette smoking cessation. Given e-health interventions' potential reach and effectiveness for waterpipe cessation, trials with large samples and long follow-up periods are needed. Future studies should use biochemical validation of abstinence to prevent the risk of detection bias. Finally,...
Source: Cancer Control - June 7, 2023 Category: Cancer & Oncology Authors: Taghrid Asfar Jonathan Livingstone-Banks Kenneth D Ward Thomas Eissenberg Olusanya Oluwole Zoran Bursac Tarek Ghaddar Wasim Maziak Source Type: research

Interventions for waterpipe smoking cessation
CONCLUSIONS: We found low-certainty evidence that behavioral waterpipe cessation interventions can increase waterpipe quit rates among waterpipe smokers. We found insufficient evidence to assess whether varenicline or bupropion increased waterpipe abstinence; available evidence is compatible with effect sizes similar to those seen for cigarette smoking cessation. Given e-health interventions' potential reach and effectiveness for waterpipe cessation, trials with large samples and long follow-up periods are needed. Future studies should use biochemical validation of abstinence to prevent the risk of detection bias. Finally,...
Source: Cochrane Database of Systematic Reviews - June 7, 2023 Category: General Medicine Authors: Taghrid Asfar Jonathan Livingstone-Banks Kenneth D Ward Thomas Eissenberg Olusanya Oluwole Zoran Bursac Tarek Ghaddar Wasim Maziak Source Type: research

Varenicline Use for Cocaine Dependence
Prim Care Companion CNS Disord. 2023 May 30;25(3):22l03375. doi: 10.4088/PCC.22l03375.NO ABSTRACTPMID:37276057 | DOI:10.4088/PCC.22l03375 (Source: Primary Care)
Source: Primary Care - June 5, 2023 Category: Primary Care Authors: Abhishek Gupta Source Type: research

Varenicline Use for Cocaine Dependence
Prim Care Companion CNS Disord. 2023 May 30;25(3):22l03375. doi: 10.4088/PCC.22l03375.NO ABSTRACTPMID:37276057 | DOI:10.4088/PCC.22l03375 (Source: The Primary Care Companion for CNS Disorders)
Source: The Primary Care Companion for CNS Disorders - June 5, 2023 Category: Primary Care Authors: Abhishek Gupta Source Type: research