The efficacy and safety of varenicline nasal spray for the management of dry eye signs: a systematic review and meta-analysis
Dry eye disease (DED) is caused by a persistently unstable tear film leading to ocular discomfort and is treated mainly with tear supplementation. There is emerging evidence that nicotinic acetylcholine recept... (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - July 14, 2023 Category: Opthalmology Authors: Bader Bashrahil, Nada Taher, Ziyad Alzahrani, Ahmed Alnabihi, Abdulaziz Aldahlawi, Mohammed Alkhathlan and Saeed Alghamdi Tags: Research Source Type: research
Cytisinicline to Speed Smoking Cessation in the United States
In 1984, the US Food and Drug Administration (FDA) approved nicotine gum as the first pharmacotherapy for cigarette smoking cessation. Other types of nicotine replacement therapy have followed (nicotine lozenges, transdermal patches, inhaler, and a nasal spray), and in 1997, the first non-nicotine pharmacotherapy, bupriopion, was approved. The FDA has not approved a new drug with an indication for smoking cessation since varenicline was approved in 2006. For over a decade, more than 50% of US adults who smoke have attempted to quit at least once each year, with around 7% of those who smoke achieving abstinence each year fo...
Source: JAMA - July 11, 2023 Category: General Medicine Source Type: research
Varenicline and counseling for vaping cessation: a double-blind, randomized, parallel-group, placebo-controlled trial
Vaping cessation is virtually unexplored. The efficacy and safety of varenicline for vaping cessation has not been studied and rigorous research is required to advance best practice and outcomes for people who... (Source: BMC Medicine)
Source: BMC Medicine - July 5, 2023 Category: Internal Medicine Authors: Pasquale Caponnetto, Davide Campagna, Jasjit S. Ahluwalia, Christopher Russell, Marilena Maglia, Paolo Marco Riela, Carmelo Fabio Longo, Barbara Busa and Riccardo Polosa Tags: Research article Source Type: research
Efficacy of varenicline versus bupropion for smoking cessation: A systematic review and meta-analysis of randomized controlled trials
Indian J Psychiatry. 2023 May;65(5):526-533. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_218_22. Epub 2023 May 15.ABSTRACTAccording to the Global Burden of Disease (GBD) Study conducted in 2019, smoking tobacco leads to over 8 million deaths each year. Hence, it is crucial to identify optimal smoking cessation therapy. To compare the efficacy of varenicline versus bupropion for smoking cessation by performing a meta-analysis of randomized controlled trials (RCTs). Protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO). The Patient intervention comparison outcome time (PICOT)...
Source: Indian Journal of Psychiatry - July 3, 2023 Category: Psychiatry Authors: Ashish R Patel Jigar R Panchal Chetna K Desai Source Type: research
