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Varenicline-induced drug eruption: case and review of the literature
We report this case since we believe no drug reaction to varenicline has had this clinical presentation or rapidity of onset. Clinicians should be aware of this potential adverse cutaneous reaction in patients taking varenicline for smoking cessation.PMID:37040914 | DOI:10.5070/D329160217 (Source: Dermatol Online J)
Source: Dermatol Online J - April 11, 2023 Category: Dermatology Authors: Catarina Correia Sonia Fernandes Teresa Correia Luis Soares-de-Almeida Paulo Filipe Source Type: research

Safety and efficacy of early varenicline prescription in hospitalized patients with acute myocardial infarction: East Asian population
CONCLUSION: This study may represent the first report on the safety and efficacy of early initiation of varenicline treatment in East Asian population hospitalized due to AMI who recently underwent percutaneous coronary intervention.PMID:37002175 | DOI:10.1016/j.jfma.2023.03.016 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 31, 2023 Category: General Medicine Authors: Chien-Hsien Lo Li-Ching Li Kai-Wei Chang Chin-Feng Tsai Chun-Hung Su Tse-Hsien Lo Chi-Hua Yen Kuei-Chuan Chan Source Type: research

Smoking cessation and vaccination
A significant proportion of COPD patients (~40%) continue smoking despite knowing that they have the disease. Smokers with COPD exhibit higher levels of nicotine dependence, and have lower self-efficacy and self-esteem, which affects their ability to quit smoking. Treatment should be adapted to the needs of individual patients with different levels of tobacco dependence. The combination of counselling plus pharmacotherapy is the most effective cessation treatment for COPD. In patients with severe COPD, varenicline and bupropion have been shown to have the highest abstinence rates compared with nicotine replacement therapy....
Source: European Respiratory Review - March 22, 2023 Category: Respiratory Medicine Authors: Montes de Oca, M., Laucho-Contreras, M. E. Tags: COPD and smoking Nonpharmacological interventions in COPD: state of the art and future directions Source Type: research

A randomized controlled trial of varenicline and brief behavioral counseling delivered by lay counselors for adolescent vaping cessation: Study protocol
DiscussionThis is the first study to evaluate varenicline in combination with a novel, brief, lay counselor delivered vaping cessation program for adolescents who vape nicotine. Results will inform clinicians on the effectiveness and acceptability of this promising, but not yet tested intervention.Clinical trial registration: ClinicalTrials.gov, identifier NCT05367492. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - March 15, 2023 Category: Psychiatry Source Type: research

IJERPH, Vol. 20, Pages 4091: Efficacy of Varenicline in the Treatment of Alcohol Dependence: An Updated Meta-Analysis and Meta-Regression
Conclusion: Our results indicated that AD patients treated with varenicline showed improvement in percentage of very heavy drinking days, percentage of abstinent days, drinks per day, drinks per drinking day, and craving. However, well-designed RCTs with a large sample size and long duration on varenicline treatment in AD remain warranted to confirm our findings. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - February 24, 2023 Category: Environmental Health Authors: Wiraphol Phimarn Rotjanawat Sakhancord Peerasaran Paitoon Kritsanee Saramunee Bunleu Sungthong Tags: Systematic Review Source Type: research