Reviewing What is Known of PTEN and its Longevity Effects
The PTEN gene shows up in a number of places in aging research, and today's paper is a review of what is known of its relevance to the field. To pick a few items, PTEN appears to be involved in some of the processes and pathways that control nutrient sensing, and is thus of interest to researchers attempting to recreate the beneficial effects of calorie restriction via pharmaceuticals. It is also involved in regeneration and cancer as a governor that prevents excessive cell growth. In this context, PTEN suppression has been shown to enhance nerve regrowth in mice, but of course there are other, adverse consequences to turn...
Source: Fight Aging! - June 6, 2017 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Why You Should Get a Second Opinion on Your Mammogram
Never say no to a second opinion, especially if you ’re concerned about breast cancer. According to a new study, radiologist subspecialists can detect breast cancer in screenings that were initially deemed negative.Lead investigator, MD and her colleaguesexamined2,400 cases that took place between January 2010 and June 2014. They discovered that 11.3 percent, or 271 patients had a malignancy. Out of the 189 patients (7.9 percent) who underwent a subsequent biopsy, 24 of them were diagnosed with cancer. In the final biopsy, radiology subspecialists found 15 cases of breast cancer, 10 invasive carcinomas, and five ductal c...
Source: radRounds - June 3, 2017 Category: Radiology Authors: Julie Morse Source Type: blogs
Adenocarcinoma in Situ : RadioPath Correlation
In situ pulmonary adenocarcinoma (AIS), previously called "Bronchioloalveolar carcinoma" (BAC), is a term describing certain variants of lung cancer arising in the distal bronchioles or alveoli that initially exhibit a specific non-invasive growth pattern. BAC is a type of non-small-cell lung cancer (NSCLC). Here is video discussing the Radio-path correlationFamous Radiology Blog http://www.sumerdoc.blogspot.com
TeleRad Providers at www.teleradproviders.com Mail us at sales@teleradproviders.com (Source: Sumer's Radiology Site)
Source: Sumer's Radiology Site - June 1, 2017 Category: Radiology Authors: Sumer Sethi Source Type: blogs
Top Companies in Genomics
From portable genome sequencers until genetic tests revealing distant relations with Thomas Jefferson, genomics represents a fascinatingly innovative area of healthcare. As the price of genome sequencing has been in free fall for years, the start-up scene is bursting from transformative power. Let’s look at some of the most amazing ventures in genomics!
The amazing journey of genome sequencing
Genome sequencing has been on an amazing scientific as well as economic journey for the last three decades. The Human Genome Project began in 1990 with the aim of mapping the whole structure of the human genome and sequencing it. ...
Source: The Medical Futurist - May 30, 2017 Category: Information Technology Authors: nora Tags: Genomics Personalized Medicine AI artificial intelligence bioinformatics cancer DNA dna testing DTC gc3 genetic disorders genetics genome sequencing personal genomics precision medicine Source Type: blogs
To be an oncologist today is to be a part of a revolution in medicine
This article was originally published in the Oncologist.
Image credit: Shutterstock.com
Your patients are rating you online: How to respond. Manage your online reputation: A social media guide. Find out how. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - May 8, 2017 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/don-s-dizon" rel="tag" > Don S. Dizon, MD < /a > Tags: Physician Cancer Source Type: blogs
Carcinoma Rectum :MRI
Discussion by Dr MGK Murthy, Dr GA PrasadMR- useful to assist staging & identify patients who may benefit from preoperative chemotherapy–radiation therapy, and in surgical planning.Currently, surgical resection with stage-appropriate neoadjuvant combined-modality therapy is the mainstay in the treatment of rectal cancer.Total mesorectal excision (TME) has reduced the prevalence of local recurrence from 38% to less than 10%. TME is surgical en bloc resection of the primary tumor and the mesorec tum by means of dissection along the mesorectal fascial plane or the circumferential resection margi...
Source: Sumer's Radiology Site - April 28, 2017 Category: Radiology Authors: Sumer Sethi Source Type: blogs
Words Matter: The Way Physicians Deliver “Bad News” Can Result in Detrimental Consequences
Delivering medical diagnosis is a sensitive practice that requires deliberate and thought out action. Of course, this isn ’t always the case, and sometimes patients receive bad news in a way that might feel cold and apathetic. The American Journal of Roentgenology recently published areportdocumenting two cases in which patients committed suicide after receiving letters from their physicians detailing “bad news”. The report ultimately determined that doctors should take precautions when delivering an unwanted diagnosis, and that “bad news” is best expressed in person.In the first case, an Israeli man who suffered...
Source: radRounds - April 22, 2017 Category: Radiology Authors: Julie Morse Source Type: blogs
What Should Primary Care Look Like in the Future?
I truly hope that very soon I do not have to make an appointment at the GP when I suspect signs of a disease, but my GP will send me a message that she spotted something irregular in my latest test results and my digital health data, so I’d better visit. Let me show you in detail, how primary care should be carried out in the future!
Digital health should become organic part of primary care in the future
I live a fairly healthy life. I use data to improve my lifestyle and to make better decisions through optimizing my sleep pattern, my physical, my cognitive or my emotional abilities; and I had several genetic tests. Wh...
Source: The Medical Futurist - April 19, 2017 Category: Information Technology Authors: nora Tags: Future of Medicine Health Sensors & Trackers digital health Education gc3 GP health trackers Healthcare Innovation primary care technology wearables Source Type: blogs
MKSAP: 44-year-old woman with a painless right neck mass
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 44-year-old woman is evaluated for a 2-month history of a painless right neck mass. Medical history is unremarkable, and she takes no medications. She is a lifelong nonsmoker.
On physical examination, vital signs are normal. A 5-cm right anterior neck mass is palpated. The remainder of the examination is unremarkable.
An initial CT scan of the neck shows a 4.5-cm, partially necrotic, right-sided lymph node. Asymmetric thickening of the right base of the tongue is also seen. Subsequent laryngoscopy shows an ulc...
Source: Kevin, M.D. - Medical Weblog - April 15, 2017 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Infectious disease Source Type: blogs
The doctor fired for having cancer speaks up
I recently reported on Stephanie Waggel, the doctor fired by a prestigious U.S. hospital for getting cancer (story also the Washington Post). In a transcription of her whistleblower video, Stephanie describes how she nearly died due to obstruction of medical care:
It started during my intern year of residency. Which, bizarrely, was the happiest year of my life. And all my friends are like, “You’re an intern, you’re not supposed to be happy, something is clearly wrong with you.” But, I’m like, “I’m out! I’m doing psychiatry. This is what I’ve always wanted to do.” I absolutely loved it. I had so much en...
Source: Kevin, M.D. - Medical Weblog - February 3, 2017 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/stephanie-waggel-and-pamela-wible" rel="tag" > Stephanie Waggel, MD and Pamela Wible, MD < /a > Tags: Physician Cancer Source Type: blogs
Artificial Intelligence System Matches Dermatologists at Skin Cancer Diagnosis
As many jobs are disappearing to automation, the latest profession to also start seeing the future may be dermatology. Stanford University researchers have developed a deep convolutional neural network, an artificial intelligence technique for building a knowledge set, to learn how to spot suspect cancer lesions.
Today this process is manual and prone to errors of subjectivity. Dermatologists simply look through a dermatoscope and judge based on their education and experience. The Stanford system was given 130,000 images of skin lesions simply labeled with previously established diagnoses that included more than 2,000 dise...
Source: Medgadget - January 26, 2017 Category: Medical Equipment Authors: Editors Tags: Dermatology Net News Source Type: blogs
progress and next steps
I had an MRI a couple of weeks ago and got the results last week. There has been slight progression in all three tumours in the brain.That ' s the bad news.The good news is that there are no new tumours and that my spine and cerebrospinal fluid remain clear, with no detectable cancer. This means that the Herceptin must be doing something for things to be progressing relatively slowly.We just have to figure out how to make it better at its job.There is very little research, when it comes to leptomeningeal disease (orleptomeningeal carcinomatosis), so in lots of ways we are making things up as we go along. The first thing we...
Source: Not just about cancer - November 30, 2016 Category: Cancer & Oncology Tags: brain metastasis breast cancer chemotherapy health care herceptin metastatic things i do for my health weird Source Type: blogs
Suddenly Everyone is Casting their Views of Aging in Terms of Cellular Senescence
I exaggerate in the title of this post, of course, but there is some truth in it. Certainly, a lot more attention is focused on the phenomenon of cellular senescence now that mouse life spans have been extended and aspects of aging have been reversed via clearance of senescent cells. The existence of several startup biotechnology companies aiming to bring senescent cell clearance treatments to the clinic is shining even more of a spotlight on this area. It has been something of a transformation. Five years ago, one of the few groups of researchers interested in this field struggled greatly to raise the funding for the pivo...
Source: Fight Aging! - November 17, 2016 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head...
Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck via Now@NEJMPosted oninfosnack. (Source: Kidney Notes)
Source: Kidney Notes - November 8, 2016 Category: Urology & Nephrology Authors: Joshua Schwimmer Source Type: blogs
Reduced Levels of Myc Regulator Mtbp Modestly Extend Life in Mice
Despite the fact that we stand within reach of human rejuvenation, to be achieved through repair of the known forms of biological damage that cause aging, the majority of research into aging and longevity has next to nothing to do with that goal. It is instead a slow and painstaking process of mapping, an attempt to understand how exactly cellular biology produces aging, at the detailed level of genes and protein interactions. It takes years of work to obtain a useful amount of new information about the role of one specific gene, and there are thousands of genes of interest, formed into networks. There are many ways to inf...
Source: Fight Aging! - November 5, 2016 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
