4 ways to protect against skin cancer (other than sunscreen)
It’s almost May and here in the northeast, front-of-the-pharmacy aisles are filled with myriad brands and types of sunscreen. While sunscreen is essential to lowering your risk for skin cancer, there are other simple, over-the-counter options you can incorporate into your summer skin protection routine. Nicotinamide may help prevent certain skin cancers Nicotinamide is a form of vitamin B3 that has been shown to reduce the number of skin cancers. In a randomized controlled trial performed in Australia (published in the New England Journal of Medicine), the risks of basal cell carcinoma and squamous cell carcinoma were si...
Source: Harvard Health Blog - April 27, 2018 Category: Consumer Health News Authors: Emily S. Ruiz, MD, MPH Tags: Cancer Health Prevention Skin and Hair Care Source Type: blogs

Eponymythology: Atraumatic Abdominal Ecchymosis
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Overview We review the original descriptions of 5 eponymous signs (n=6) associated with non-traumatic abdominal ecchymosis. These commonly cited eponyms involving the abdominal wall and flanks (Grey Turner, Cullen and Stabler); scrotum (Bryant) and upper thigh (Fox) may be useful clues directing the examiner to consider potentially serious causes of abdominal pathology. Cullen sign Thomas Stephen Cullen (1869–1953) was a Canadian gynecologist Non-traumatic peri-um...
Source: Life in the Fast Lane - April 18, 2018 Category: Emergency Medicine Authors: Mike Cadogan Tags: Eponymythology Abdominal Ecchymosis Bryant sign Cullen sign fox sign Francis Edward Stabler George Grey Turner Grey Turner sign John Adrian Fox John Henry Bryant Stabler sign Thomas Stephen Cullen Source Type: blogs

Learning to Learn as a Medical Student
By: Alyssa B. Smith, third-year medical student, Chicago Medical School I began at Chicago Medical School believing the notion that my study methods had gotten me into medical school, so they could therefore get me through medical school. I quickly realized that was a false perception. The volume of material, necessity to retain this material past each exam, and building of knowledge requires stronger learning methods than those I had used in the past, like relying on flashcards to memorize topics. That’s when I turned to the six study strategies—including spaced practice, interleaving, and elaborate integration—I ha...
Source: Academic Medicine Blog - April 17, 2018 Category: Universities & Medical Training Authors: Guest Author Tags: Featured Trainee Perspective assessment medical education medical students Source Type: blogs

Tumor Size (Size of Invasive Carcinoma) in Breast Carcinoma
Breast Carcinoma reporting;Tumor Size (Size of Invasive Carcinoma)The size of an invasive carcinoma is an important prognostic factor. The single greatest dimension of the largest invasive carcinoma is used to determine T classification The best size for AJCC T classification should use information from imaging, gross examination, and microscopic evaluation. Visual determination of size is often unreliable, as carcinomas often blend into adjacent fibrous tissue. The size by palpation of a hard mass correlates better with invasion of tumor cells into stroma with a desmoplastic response. Sizes should...
Source: Oncopathology - April 12, 2018 Category: Cancer & Oncology Source Type: blogs

MKSAP: 57-year-old man with chronic hepatitis C infection
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 57-year-old man is evaluated during a routine examination. His medical history is notable for chronic hepatitis C infection with cirrhosis, which was diagnosed 3 years ago. He undergoes surveillance ultrasound for hepatocellular carcinoma every 6 months. On physical examination, temperature is 36.8 °C (98.2 °F), blood pressure is 110/82 mm Hg, pulse rate is 65/min, and respiration rate is 18/min; BMI is 22. Muscle wasting and scleral icterus are noted. There is no flank dullness and no asterixis. Ultrasound ...
Source: Kevin, M.D. - Medical Weblog - March 31, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Gastroenterology Oncology/Hematology Source Type: blogs

Tropical Travel Trouble 005 RUQ Pain and Jaundice
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 005 Guest Post: Dr Branden Skarpiak – Global Health Fellow, Department of Emergency Medicine. UT Health San Antonio A 35 year old male presents to your emergency room for right upper quadrant pain that has gotten worse over the last 2-3 days. He also describes associated nausea, vomiting, and fevers. He denies other abdominal pain, or change in his bowel or bladder habits. His wife notes that he has started to “look more yellow” recent...
Source: Life in the Fast Lane - March 19, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine amebic amoeba amoebiasis amoebic dysentery amoebic liver abscess bloody diarrhoea e.dispar e.histolytica entamoeba histolytica Source Type: blogs

Featured Neuropathologist: Michael Punsoni, MD
On occasion, we profile a prominent or rising neuropathologist. In the past, we ' ve featured the likes of Craig Horbinski, Roger McLendon,Jan Leestma, and Karra Jones. Today we featureMichael Punsoni, MD, a 2016 graduate of the Brown University Neuropathology Fellowship Program and now on faculty at the University of Nebraska in Omaha. Dr. Punsoni agreed to engage in a little Q&A:1. Why did you decide to become a neuropathologist?I have always had a strong interest in science and medicine, particularly the neurosciences. After college I worked in two research labs, which fueled my interest in basic...
Source: neuropathology blog - March 12, 2018 Category: Radiology Tags: neuropathologists Source Type: blogs

Senolytic Drugs Fail to Kill Cancerous Cells with Senescent Gene Expression Signatures, but a Gene Therapy Succeeds
Some cancerous cells express signatures normally associated with senescent cells, so why not try senolytic compounds against them? This is something of a full circle, given that most of the current senolytic drug candidates were originally characterized and tested as potential chemotherapeutics. The open access paper here is interesting for two points: firstly, that senolytic drugs didn't kill cancerous cells with a senescent signature, and secondly that a suicide gene therapy targeting that signature does work against both normal senescent cells and cancerous cells with a senescent signature. The gene therapy approach rep...
Source: Fight Aging! - March 7, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

What If The Pathologist Is Wrong?
And they won ' t review all the tests. This is a two part misadventure.First I was horrified by thisfirst story where two women were found to have been misdiagnosed by a pathologist at a hospital in Ireland. Their original breast cancer diagnoses were incorrect. One woman was diagnosed with DCIS in 2010 and had a mastectomy. Based on the original pathology she was not required to have any additional treatment. In 2012, to the surprise of her and her doctor, her cancer came back." Her original 2010 biopsy had shown invasive cancer but this had been missed.The hospital said this was a mistake that any pathologist could have ...
Source: Caroline's Breast Cancer Blog - February 22, 2018 Category: Cancer & Oncology Tags: breast cancer treatment cancer diagnosis medical errors pathology report Source Type: blogs

Medmastery: Detecting malignant focal lesions.
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog The team at Medmastery are providing LITFL readers with a series of FOAMed courses from across their website. In this video, from the Abdominal Ultrasound Essentials course, Dr. Nikolaus Mayr discusses the basic principles of liver ultrasound including the differentiation of malignant pathologies such as hepatocellular carcinoma (HCC), cholangiocarcinoma and metastases. Further reading: LITFL Medmastery Courses Medmastery on Facebook and Twitter Guest post: Nikola...
Source: Life in the Fast Lane - February 20, 2018 Category: Emergency Medicine Authors: Mike Cadogan Tags: Medmastery liver malignant Ultrasound Source Type: blogs

Medmastery: Detecting malignant focal lesions
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog The team at Medmastery are providing LITFL readers with a series of FOAMed courses from across their website. In this video, from the Abdominal Ultrasound Essentials course, Dr. Nikolaus Mayr discusses the basic principles of liver ultrasound including the differentiation of malignant pathologies such as hepatocellular carcinoma (HCC), cholangiocarcinoma and metastases. Further reading: LITFL Medmastery Courses Medmastery on Facebook and Twitter G...
Source: Life in the Fast Lane - February 20, 2018 Category: Emergency Medicine Authors: Mike Cadogan Tags: Medmastery liver malignant Ultrasound Source Type: blogs

Precision Medicine and Public Health (from Precision Medicine and the Reinvention of Human Disease)
Excerpted fromPrecision Medicine and the Reinvention of Human DiseaseDespite having the most advanced healthcare technology on the planet, life expectancy in the United States is not particularly high. Citizens from most of the European countries and the highly industrialized Asian countries enjoy longer life expectancies than the United States. According to the World Health Organization, the United States ranks 31st among nations, trailing behind Greece, Chile, and Costa Rica, and barely edging out Cuba [42]. Similar rankings are reported by the US Central Intelligence Agency [43]. These findings lead us to infer that acc...
Source: Specified Life - February 6, 2018 Category: Information Technology Tags: cancer cancer vaccines precision medicine prevention public health Source Type: blogs

Insurers, Not Legislators, are the Gatekeepers to Care, and a Call to Deep Six the Term "Worried Well."
Over onPete Earley's blog, there is a post titled:Senators ’ Letter To SAMHSA Is Misguided: Dr. McCance-Katz Is Doing What Congress DemandedPete is on the Interdepartmental Serious Mental Illness Coordinating Committee,  a group operating under the Department of Health and Human Services. He is an extraordinary writer and a tremendous mental health advocate.  His post inspired me to rant at him (Me rant?  Shocking, I know...) and Pete and I are both posting my response.  I can't begin to capture the essence of his post on the controversy over the NREPP website, nor will you need to understand that to ...
Source: Shrink Rap - February 1, 2018 Category: Psychiatry Authors: Dinah Source Type: blogs