A Retrospective Chart Review of Buspirone for the Treatment of Anxiety in Psychiatrically Referred Youth with High-Functioning Autism Spectrum Disorder
Journal of Child and Adolescent Psychopharmacology, Ahead of Print. (Source: Journal of Child and Adolescent Psychopharmacology)
Source: Journal of Child and Adolescent Psychopharmacology - November 16, 2018 Category: Pediatrics Authors: Tolga Atilla Ceranoglu Janet Wozniak Ronna Fried Maribel Galdo Barbora Hoskova Melissa DeLeon Fong Joseph Biederman Gagan Joshi Source Type: research
Characteristics of metabolic stability and the cell permeability of 2 ‐pyrimidynyl‐piperazinyl‐alkyl derivatives of 1H‐imidazo[2,1‐f]purine‐2,4(3H,8H)‐dione with antidepressant‐ and anxiolytic‐like activity
This article is protected by copyright. All rights reserved. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - November 13, 2018 Category: Biology Authors: Agnieszka Zag órska,
Anna Partyka,
Adam Bucki,
Marcin Kołaczkowski,
Magdalena Jastrzębska‐Więsek,
Anna Czopek,
Agata Siwek,
Monika Głuch‐Lutwin,
Marek Bednarski,
Marek Bajda,
Jakub Jończyk,
Kamil Piska,
Paulina Koczurkiewicz,
Anna W Tags: Research Article Source Type: research
5.19 Buspirone for the Treatment of Anxiety in Psychiatrically Referred Youth With ASD: A Retrospective Chart Review
This study examines the yet-unexplored tolerability and efficacy of buspirone in treating ADs comorbid with ASD. (Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - October 1, 2018 Category: Psychiatry Authors: Tolga Atilla Ceranoglu, Janet Wozniak, Ronna S. Fried, Maribel Galdo, Barbora Hoskova, Melissa DeLeon Fong, Maura Fitzgerald, Joseph Biederman, Gagan Joshi Source Type: research
Efficacy and safety of drugs for attention deficit hyperactivity disorder in children and adolescents: a network meta-analysis
AbstractThe aim of this study is to gather evidence of head-to-head double-blind randomized-controlled trials on the efficacy and safety of available treatments for attention deficit hyperactivity disorder (ADHD) in children and adolescents. A systematic review was conducted by two independent reviewers in ten electronic databases (PROSPERO register CRD42016043239). Methodological quality of included studies was evaluated according to the Jadad scale. Network meta-analyses were performed including double-blinded head-to-head trials comparing active allopathic drugs in patients (0 –18 years old) diagnosed with ADHD. The r...
Source: European Child and Adolescent Psychiatry - October 1, 2018 Category: Psychiatry Source Type: research
Detection of potential look-alike/sound-alike medication errors using Veterans Affairs administrative databases.
CONCLUSION: Through the use of administrative databases, potential LASA errors that could be reviewed for an actual error via chart review were identified. While a high rate of potential LASA errors was detected, the number of actual errors identified was low.
PMID: 30257842 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - September 29, 2018 Category: Drugs & Pharmacology Authors: Zacher JM, Cunningham FE, Zhao X, Burk ML, Moore VR, Good CB, Glassman PA, Aspinall SL Tags: Am J Health Syst Pharm Source Type: research
Pharmacotherapy of Down Syndrome.
This article reviews the literature on the pharmacotherapy of psychiatric conditions co-occurring with DS, including major depressive disorder (MDD), bipolar disorder, anxiety disorders, obsessive-compulsive disorder (OCD), attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), psychosis, and catatonia. A section on the phenomenon of regression is included. Expert opinion: For MDD, we typically begin with selective serotonin reuptake inhibitors (SSRIs). For bipolar disorder, we often use carbamazepine. For psychotic symptoms, we begin with risperidone or aripiprazole. We use buspirone to treat anx...
Source: Expert Opinion on Pharmacotherapy - September 28, 2018 Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Pharmacological treatment of anxiety disorders in adults with epilepsy.
PHARMACOLOGICAL TREATMENT OF ANXIETY DISORDERS IN ADULTS WITH EPILEPSY.
Expert Opin Pharmacother. 2018 Sep 25;:
Authors: Mula M
Abstract
INTRODUCTION: Anxiety disorders represent one of the most frequently encountered comorbidities in patients with epilepsy, affecting quality of life and increasing, morbidity, mortality and healthcare costs. However, they are still underdiagnosed and undertreated. Areas covered: This is a narrative review of the pharmacological treatment of anxiety disorders in adult patients with epilepsy discussing also major issues regarding pathophysiology and...
Source: Expert Opinion on Pharmacotherapy - September 27, 2018 Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Dose related effects of buspirone on pain, learning / memory and food intake
Publication date: Available online 19 September 2018Source: Regulatory Toxicology and PharmacologyAuthor(s): Darakhshan Jabeen Haleem, Shazia Nawaz, Tabinda SalmanAbstractThe present study concerned extending the therapeutic use of buspirone for treating pain and improving cognition. Effects of single and repeated administration of buspirone were therefore monitored on pain threshold in the hot plate test and on spatial memory in the water maze test in rats. Effects on cumulative food intake were also monitored. The drug was administered intraperitoneally in doses of 0.1, 0.3, 1.0 and 2.0 mg/kg. We found that single and ...
Source: Regulatory Toxicology and Pharmacology - September 21, 2018 Category: Toxicology Source Type: research
New developments in the treatment of gastroparesis and functional dyspepsia.
Abstract
Functional dyspepsia (FD) and gastroparesis are frequent causes of upper gastrointestinal symptoms such as postprandial fullness, early satiation, epigastric pain or burning, upper abdominal bloating, bothersome belching, nausea and vomiting. The underlying pathophysiological mechanisms are heterogeneous and involved mechanisms such as abnormal gastric motility (accommodation, emptying), visceral hypersensitivity, low grade mucosal inflammation and cellular changes in enteric nerves, muscle or interstitial cells of Cajal. Patient-reported outcomes for evaluating treatment efficacy in these conditi...
Source: Current Opinion in Pharmacology - September 20, 2018 Category: Drugs & Pharmacology Authors: Tack J, Camilleri M Tags: Curr Opin Pharmacol Source Type: research
Dose related effects of buspirone on pain, learning / memory and food intake.
Abstract
The present study concerned extending the therapeutic use of buspirone for treating pain and improving cognition. Effects of single and repeated administration of buspirone were therefore monitored on pain threshold in the hot plate test and on spatial memory in the water maze test in rats. Effects on cumulative food intake were also monitored. The drug was administered intraperitoneally in doses of 0.1, 0.3, 1.0 and 2.0 mg/kg. We found that single and repeated administration of buspirone in doses of 0.1 mg/kg decreased pain threshold in the hot plate test, while doses of 1.0 and 2.0 mg/kg i...
Source: Regulatory Toxicology and Pharmacology : RTP - September 19, 2018 Category: Toxicology Authors: Haleem DJ, Nawaz S, Salman T Tags: Regul Toxicol Pharmacol Source Type: research
Pharmacotherapy of adjustment disorder: A review.
CONCLUSIONS: The work done has been useful insofar as it provides clinicians with some insights into the advantages and disadvantages of a number of pharmacotherapy options. Additional rigorously designed trials are needed to further advance the field.
PMID: 30204560 [PubMed - in process] (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - September 13, 2018 Category: Psychiatry Authors: Stein DJ Tags: World J Biol Psychiatry Source Type: research
Fluoxetine-Induced Sleep Bruxism Rapidly Treated With Once-Nightly Dosing of Buspirone in a 6-Year-Old Girl
We report the case of a 6-year-old girl who was successfully treated with once-nightly dosing of buspirone for fluoxetine-induced sleep bruxism, which was confirmed with clear on-off-on treatment sequence. (Source: Clinical Neuropharmacology)
Source: Clinical Neuropharmacology - September 1, 2018 Category: Neurology Tags: Case Reports Source Type: research
Chronic minocycline treatment reduces the anxiety-like behaviors induced by repeated restraint stress through modulating neuroinflammation.
In conclusion, our findings support the hypothesis that immune dysregulation plays an important role in stress-induced anxiety disorders, and minocycline can be developed to be used in these diseases.
PMID: 30149196 [PubMed - as supplied by publisher] (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - August 24, 2018 Category: Neurology Authors: Haiyan L, Jiao Y, Lining H, Lifei C, Xinshang W, Xiaojuan W, Feng B Tags: Brain Res Bull Source Type: research
The central effects of buspirone on abdominal pain in rats
Neurogastroenterology&Motility, EarlyView. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - August 13, 2018 Category: Gastroenterology Authors: S. S. Panteleev
,
I. B. Sivachenko
,
O. A. Lyubashina Source Type: research
