The dysphagia stress test for rapid assessment of swallowing difficulties in esophageal conditions
Conclusions& InferencesThe DST is the first rapid assessment tool designed for gastroenterology clinics with direct observation of swallowing ability across several conditions to mitigate issues related to patient self ‐report of esophageal symptoms. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 25, 2018 Category: Gastroenterology Authors: Tiffany H. Taft,
Emily Kern,
Kristen Starkey,
Jenna Craft,
Meredith Craven,
Bethany Doerfler,
Laurie Keefer,
Peter Kahrilas,
John Pandolfino Tags: ORIGINAL ARTICLE Source Type: research
Probiotics in irritable bowel syndrome: Where are we?
AbstractWe have only recently begun to understand how alterations of the intestinal microbial ecosystem lead to the disruption of host ‐microbial interactions and are associated with diseases, including functional gastrointestinal disorders such as irritable bowel syndrome (IBS). Although we are still far from understanding the human microbiome, gut microbiota is already a therapeutic target. Probiotics are live microorganisms th at, when administered in adequate amounts, confer a health benefit to the host and may represent a therapeutic option for diseases characterized by dysbiosis such as IBS. Meta‐analyses suggest...
Source: Neurogastroenterology and Motility - November 20, 2018 Category: Gastroenterology Authors: Giovanni Barbara,
Cesare Cremon,
Fernando Azpiroz Tags: MINI ‐REVIEW Source Type: research
Cover Image
The cover image is based on the Original ArticleExploring pyloric dynamics in stenting using a distensibility technique by Jorge Alberto Arroyo V ázquez et al., DOI:10.1111/nmo.13445. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 20, 2018 Category: Gastroenterology Authors: Jorge Alberto Arroyo V ázquez,
Maria Bergström,
Stephen Bligh,
Barry P. McMahon,
Per‐Ola Park Tags: COVER IMAGE Source Type: research
Issue Information
Neurogastroenterology&Motility, Volume 30, Issue 12, December 2018. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 20, 2018 Category: Gastroenterology Tags: ISSUE INFORMATION Source Type: research
Corrigendum
Neurogastroenterology&Motility, Volume 30, Issue 12, December 2018. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 20, 2018 Category: Gastroenterology Tags: CORRIGENDUM Source Type: research
The Experience Sampling Method —Evaluation of treatment effect of escitalopram in IBS with comorbid panic disorder
Conclusions& InferencesReal ‐time ESM has the potential to capture treatment response more sensitively compared to a retrospective end‐of‐day GI symptom diary and the GSRS, by taking into account day‐to‐day symptom variability as well as momentary factors that might moderate treatment effect, such as anxiety. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 20, 2018 Category: Gastroenterology Authors: Lisa Vork,
Zlatan Mujagic,
Marjan Drukker,
Daniel Keszthelyi,
Jos é M. Conchillo,
Martine A. M. Hesselink,
Jim van Os,
Ad A. M. Masclee,
Carsten Leue,
Joanna W. Kruimel Tags: ORIGINAL ARTICLE Source Type: research
The temporal relationship of daily life stress, emotions, and bowel symptoms in irritable bowel syndrome —Diarrhea subtype: A smartphone‐based experience sampling study
Conclusions and InferencesESM unveiled the dynamic relationship between bowel symptoms, stress, and emotionality. Patients with IBS ‐D responded to bowel symptoms with more stress and distress momentarily. Counter‐intuitively, daily life activity stress appeared to ameliorate bowel symptoms, although a more rigorous study design is required to testify this claim. Psychological understanding of IBS‐D is discussed. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 18, 2018 Category: Gastroenterology Authors: Yawen Chan,
Suzanne Ho ‐wai So,
Arthur Dun Ping Mak,
Kewin Tien Ho Siah,
Wai Chan,
Justin C. Y. Wu Tags: ORIGINAL ARTICLE Source Type: research
Irritable bowel syndrome, mental health, and quality of life: Data from a population ‐based survey in Germany (SHIP‐Trend‐0)
Conclusions& InferencesIBS prevalence was relatively low compared to other studies. Factors predicting IBS were of biological, psychological, and social nature. The association between IBS and pain in different areas of the body indicates a potential underlying complex somatic symptom disorder. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 15, 2018 Category: Gastroenterology Authors: Birgit Schauer,
Hans J. Grabe,
Till Ittermann,
Markus M. Lerch,
Frank U. Weiss,
Hubert M önnikes,
Henry Völzke,
Paul Enck,
Juliane Schwille‐Kiuntke Tags: ORIGINAL ARTICLE Source Type: research
Clinical features and long ‐term outcomes of lower esophageal sphincter‐dependent and lower esophageal sphincter‐independent jackhammer esophagus
Conclusions and InferencesOur findings suggest that LD ‐JHE and LI‐JHE are clinically indistinguishable and thus support existing diagnostic criteria. Furthermore, our long‐term follow‐up data suggest that JHE, irrespective of LES involvement, may improve without treatment. Further study is needed to clarify which patients merit therapeutic inte rvention. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 15, 2018 Category: Gastroenterology Authors: Allon Kahn,
Mohanad T. Al ‐Qaisi,
Robert A. Obeid,
David A. Katzka,
Karthik M. Ravi,
Francisco C. Ramirez,
Michael D. Crowell,
Marcelo F. Vela Tags: ORIGINAL ARTICLE Source Type: research
High ‐resolution impedance manometry parameters in the evaluation of esophageal function of non‐obstructive dysphagia patients
Conclusion& InferencesThese novel pressure ‐impedance measures may aid in the evaluation of NOD patients by revealing abnormal motor patterns, which may explain symptom generation. Future studies are needed to evaluate which of these measures are worthy of calculation and to establish protocol settings that allow for their meaningful inter pretation. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 13, 2018 Category: Gastroenterology Authors: Maartje J. Singendonk,
Zhiyue Lin,
Charlotte Scheerens,
Jan Tack,
Dustin A. Carlson,
Taher I. Omari,
John E. Pandolfino,
Nathalie Rommel Tags: ORIGINAL ARTICLE Source Type: research
Audit of the diagnosis of rectal evacuation disorders in chronic constipation
Conclusions& InferencesThe clinical diagnosis of RED in patients with CC is achieved with combination of DRE, HRM and an optimized, time ‐based BET. Prospective studies are necessary to confirm the proposed 22 second cutoff for tbBET. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 13, 2018 Category: Gastroenterology Authors: Victor Chedid,
Priya Vijayvargiya,
Houssam Halawi,
Seon ‐Young Park,
Michael Camilleri Tags: ORIGINAL ARTICLE Source Type: research
Detecting the effects of a standardized meal challenge on small bowel motility with MRI in prepared and unprepared bowel
Conclusion& InferencesA significant response to a 300 ‐kcal meal was measured within 10 minutes in unprepared bowel, supporting the clinical use of this challenge to provoke and assess motility changes. A caloric challenge did not produce an observable increase in motility in mannitol prepared subjects. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 8, 2018 Category: Gastroenterology Authors: Catharina S. de Jonge,
Alex Menys,
Kyra L. van Rijn,
Arjan J. Bredenoord,
Aart J. Nederveen,
Jaap Stoker Tags: ORIGINAL ARTICLE Source Type: research
Upregulation of intestinal mucosal mast cells expressing VPAC1 in close proximity to vasoactive intestinal polypeptide in inflammatory bowel disease and murine colitis
Conclusions and InferencesCommunication between MCs and VIP is upregulated during IBD and mice colitis. In CD patients, the epithelium next to FAE seems to be more involved than the surrounding VE, suggesting increased MC ‐VIP‐interactions in this intestinal region. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 8, 2018 Category: Gastroenterology Authors: Maite Casado ‐Bedmar,
Stéphanie D. S. Heil,
Pär Myrelid,
Johan D. Söderholm,
Åsa V. Keita Tags: ORIGINAL ARTICLE Source Type: research
Non ‐invasive transcutaneous auricular vagus nerve stimulation prevents postoperative ileus and endotoxemia in mice
ConclusiontVNS prevents intestinal and systemic inflammation. Activation of the DMV indicates an afferent to efferent central circuitry of the tVNS stimulation and the beneficial effects of tVNS depend on an intact vagus nerve. tVNS may become a non ‐invasive approach for treatment of POI. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 8, 2018 Category: Gastroenterology Authors: Gun ‐Soo Hong,
Anne Zillekens,
Bianca Schneiker,
Dimitrios Pantelis,
Wouter Jonge,
Nico Schaefer,
Joerg C. Kalff,
Sven Wehner Tags: ORIGINAL ARTICLE Source Type: research
Alterations of colonic sensitivity and gastric dysmotility after acute cisplatin and granisetron
Conclusions and InferencesCisplatin ‐induced bedding intake and gastric dysmotility were blocked by granisetron, confirming the involvement of serotonin acting on 5‐HT3 receptors. Unexpectedly, visceral sensitivity to colonic distension was reduced, to the same extent, by cisplatin, granisetron, and their combination, suggesting important mechanistic differences with nausea and gastric dysmotility that warrant further investigation. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - November 6, 2018 Category: Gastroenterology Authors: Marta Mart ín‐Ruíz,
José A. Uranga,
Paula Mosinska,
Jakub Fichna,
Kulmira Nurgali,
Mª Isabel Martín‐Fontelles,
Raquel Abalo Tags: ORIGINAL ARTICLE Source Type: research
