Clinical practice guideline on pharmacological and psychological management of adult patients with an Anxiety Disorder and comorbid substance use
Adicciones. 2021 Jun 14;0(0):1548. doi: 10.20882/adicciones.1548. Online ahead of print.ABSTRACTThis review synthesizes the pharmacological and psychosocial interventions that have been conducted in comorbid anxiety disorders and SUDs while also providing clinical recommendations about which intervention elements are helpful for addressing substance use versus anxiety symptoms in patients with these co-occurring conditions. The best evidence from randomized controlled trials was used to evaluate treatment options. The strength of recommendations was described using the GRADE approach. Clinical trials are only available for...
Source: Adicciones - June 25, 2021 Category: Addiction Authors: Pilar Alejandra S áiz Gerardo Florez Manuel Arrojo Miquel Bernardo Ana Gonz ález-Pinto Jos é Manuel Goikolea I ñaki Zorrilla Ruth Cunill Xavier Castells Elisardo Beco ña Ana L ópez Marta Torrens Francina Fonseca Judit Tirado-Mu ñoz Bel én Arranz M Source Type: research

Clinical practice guideline on pharmacological and psychological management of adult patients with an Anxiety Disorder and comorbid substance use
Adicciones. 2021 Jun 14;0(0):1548. doi: 10.20882/adicciones.1548. Online ahead of print.ABSTRACTThis review synthesizes the pharmacological and psychosocial interventions that have been conducted in comorbid anxiety disorders and SUDs while also providing clinical recommendations about which intervention elements are helpful for addressing substance use versus anxiety symptoms in patients with these co-occurring conditions. The best evidence from randomized controlled trials was used to evaluate treatment options. The strength of recommendations was described using the GRADE approach. Clinical trials are only available for...
Source: Adicciones - June 25, 2021 Category: Addiction Authors: Pilar Alejandra S áiz Gerardo Florez Manuel Arrojo Miquel Bernardo Ana Gonz ález-Pinto Jos é Manuel Goikolea I ñaki Zorrilla Ruth Cunill Xavier Castells Elisardo Beco ña Ana L ópez Marta Torrens Francina Fonseca Judit Tirado-Mu ñoz Bel én Arranz M Source Type: research

Clinical practice guideline on pharmacological and psychological management of adult patients with an Anxiety Disorder and comorbid substance use
Adicciones. 2021 Jun 14;0(0):1548. doi: 10.20882/adicciones.1548. Online ahead of print.ABSTRACTThis review synthesizes the pharmacological and psychosocial interventions that have been conducted in comorbid anxiety disorders and SUDs while also providing clinical recommendations about which intervention elements are helpful for addressing substance use versus anxiety symptoms in patients with these co-occurring conditions. The best evidence from randomized controlled trials was used to evaluate treatment options. The strength of recommendations was described using the GRADE approach. Clinical trials are only available for...
Source: Adicciones - June 25, 2021 Category: Addiction Authors: Pilar Alejandra S áiz Gerardo Florez Manuel Arrojo Miquel Bernardo Ana Gonz ález-Pinto Jos é Manuel Goikolea I ñaki Zorrilla Ruth Cunill Xavier Castells Elisardo Beco ña Ana L ópez Marta Torrens Francina Fonseca Judit Tirado-Mu ñoz Bel én Arranz M Source Type: research

Clinical practice guideline on pharmacological and psychological management of adult patients with an Anxiety Disorder and comorbid substance use
Adicciones. 2021 Jun 14;0(0):1548. doi: 10.20882/adicciones.1548. Online ahead of print.ABSTRACTThis review synthesizes the pharmacological and psychosocial interventions that have been conducted in comorbid anxiety disorders and SUDs while also providing clinical recommendations about which intervention elements are helpful for addressing substance use versus anxiety symptoms in patients with these co-occurring conditions. The best evidence from randomized controlled trials was used to evaluate treatment options. The strength of recommendations was described using the GRADE approach. Clinical trials are only available for...
Source: Adicciones - June 25, 2021 Category: Addiction Authors: Pilar Alejandra S áiz Gerardo Florez Manuel Arrojo Miquel Bernardo Ana Gonz ález-Pinto Jos é Manuel Goikolea I ñaki Zorrilla Ruth Cunill Xavier Castells Elisardo Beco ña Ana L ópez Marta Torrens Francina Fonseca Judit Tirado-Mu ñoz Bel én Arranz M Source Type: research

Clinical practice guideline on pharmacological and psychological management of adult patients with an Anxiety Disorder and comorbid substance use
Adicciones. 2021 Jun 14;0(0):1548. doi: 10.20882/adicciones.1548. Online ahead of print.ABSTRACTThis review synthesizes the pharmacological and psychosocial interventions that have been conducted in comorbid anxiety disorders and SUDs while also providing clinical recommendations about which intervention elements are helpful for addressing substance use versus anxiety symptoms in patients with these co-occurring conditions. The best evidence from randomized controlled trials was used to evaluate treatment options. The strength of recommendations was described using the GRADE approach. Clinical trials are only available for...
Source: Adicciones - June 25, 2021 Category: Addiction Authors: Pilar Alejandra S áiz Gerardo Florez Manuel Arrojo Miquel Bernardo Ana Gonz ález-Pinto Jos é Manuel Goikolea I ñaki Zorrilla Ruth Cunill Xavier Castells Elisardo Beco ña Ana L ópez Marta Torrens Francina Fonseca Judit Tirado-Mu ñoz Bel én Arranz M Source Type: research

Clinical practice guideline on pharmacological and psychological management of adult patients with an Anxiety Disorder and comorbid substance use
Adicciones. 2021 Jun 14;0(0):1548. doi: 10.20882/adicciones.1548. Online ahead of print.ABSTRACTThis review synthesizes the pharmacological and psychosocial interventions that have been conducted in comorbid anxiety disorders and SUDs while also providing clinical recommendations about which intervention elements are helpful for addressing substance use versus anxiety symptoms in patients with these co-occurring conditions. The best evidence from randomized controlled trials was used to evaluate treatment options. The strength of recommendations was described using the GRADE approach. Clinical trials are only available for...
Source: Adicciones - June 25, 2021 Category: Addiction Authors: Pilar Alejandra S áiz Gerardo Florez Manuel Arrojo Miquel Bernardo Ana Gonz ález-Pinto Jos é Manuel Goikolea I ñaki Zorrilla Ruth Cunill Xavier Castells Elisardo Beco ña Ana L ópez Marta Torrens Francina Fonseca Judit Tirado-Mu ñoz Bel én Arranz M Source Type: research

Clinical practice guideline on pharmacological and psychological management of adult patients with an Anxiety Disorder and comorbid substance use
Adicciones. 2021 Jun 14;0(0):1548. doi: 10.20882/adicciones.1548. Online ahead of print.ABSTRACTThis review synthesizes the pharmacological and psychosocial interventions that have been conducted in comorbid anxiety disorders and SUDs while also providing clinical recommendations about which intervention elements are helpful for addressing substance use versus anxiety symptoms in patients with these co-occurring conditions. The best evidence from randomized controlled trials was used to evaluate treatment options. The strength of recommendations was described using the GRADE approach. Clinical trials are only available for...
Source: Adicciones - June 25, 2021 Category: Addiction Authors: Pilar Alejandra S áiz Gerardo Florez Manuel Arrojo Miquel Bernardo Ana Gonz ález-Pinto Jos é Manuel Goikolea I ñaki Zorrilla Ruth Cunill Xavier Castells Elisardo Beco ña Ana L ópez Marta Torrens Francina Fonseca Judit Tirado-Mu ñoz Bel én Arranz M Source Type: research

Clinical practice guideline on pharmacological and psychological management of adult patients with an Anxiety Disorder and comorbid substance use
Adicciones. 2021 Jun 14;0(0):1548. doi: 10.20882/adicciones.1548. Online ahead of print.ABSTRACTThis review synthesizes the pharmacological and psychosocial interventions that have been conducted in comorbid anxiety disorders and SUDs while also providing clinical recommendations about which intervention elements are helpful for addressing substance use versus anxiety symptoms in patients with these co-occurring conditions. The best evidence from randomized controlled trials was used to evaluate treatment options. The strength of recommendations was described using the GRADE approach. Clinical trials are only available for...
Source: Adicciones - June 25, 2021 Category: Addiction Authors: Pilar Alejandra S áiz Gerardo Florez Manuel Arrojo Miquel Bernardo Ana Gonz ález-Pinto Jos é Manuel Goikolea I ñaki Zorrilla Ruth Cunill Xavier Castells Elisardo Beco ña Ana L ópez Marta Torrens Francina Fonseca Judit Tirado-Mu ñoz Bel én Arranz M Source Type: research

Management of Ineffective Esophageal Hypomotility
Esophageal hypomotility in general and especially ineffective esophageal motility according to the Chicago criteria of primary motility disorders of the esophagus, is one of the most frequently diagnosed motility disorders on high resolution manometry and results in a large number of patients visiting gastroenterologists. Most patients with esophageal hypomotility present with gastroesophageal reflux symptoms or dysphagia. The clinical relevance of the motility pattern, however, is not well established but seems to be correlated with disease severity in reflux patients. The correlation with dysphagia is less clear. Prokine...
Source: Frontiers in Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Source Type: research

Benefit of buspirone on chemoreflex and central apnoeas in heart failure: a randomized controlled crossover trial
ConclusionsBuspirone reduces CO2 chemosensitivity and improves CA and oxygen saturation across the 24  h in patients with HF. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - March 30, 2021 Category: Cardiology Authors: Alberto Giannoni, Chiara Borrelli, Gianluca Mirizzi, George B. Richerson, Michele Emdin, Claudio Passino Tags: Research article Source Type: research

Buspirone Dose-Response on Facilitating Forelimb Functional Recovery in Cervical Spinal Cord Injured Rats
In this study, we investigated the dose-response of Buspirone treatment on reaching and grasping function in cervical cord injured rats. Seventeen adult Sprague-Dawley rats were trained to reach and grasp sugar pellets before a C4 bilateral dorsal column crush injury. After 1 week post-injury, the rats were divided into 3 groups to receive 1 of 3 different dosages of Buspirone (i.p., 1 dose/day: 1.5, n = 5; 2.5, n = 6 and 3.5 mg/kg b.w., n = 6). Forelimb reaching and grip strength test were recorded once per week, within 1 hour of Buspirone administration for 11 weeks post-injury. Different dose groups began to exhibit dif...
Source: Dose Response - March 15, 2021 Category: Drugs & Pharmacology Authors: Rakib Uddin Ahmed V Reggie Edgerton Shuai Li Yong-Ping Zheng Monzurul Alam Source Type: research

Buspirone Dose-Response on Facilitating Forelimb Functional Recovery in Cervical Spinal Cord Injured Rats
In this study, we investigated the dose-response of Buspirone treatment on reaching and grasping function in cervical cord injured rats. Seventeen adult Sprague-Dawley rats were trained to reach and grasp sugar pellets before a C4 bilateral dorsal column crush injury. After 1 week post-injury, the rats were divided into 3 groups to receive 1 of 3 different dosages of Buspirone (i.p., 1 dose/day: 1.5, n = 5; 2.5, n = 6 and 3.5 mg/kg b.w., n = 6). Forelimb reaching and grip strength test were recorded once per week, within 1 hour of Buspirone administration for 11 weeks post-injury. Different dose groups began to exhibit dif...
Source: Dose Response - March 15, 2021 Category: Drugs & Pharmacology Authors: Rakib Uddin Ahmed V Reggie Edgerton Shuai Li Yong-Ping Zheng Monzurul Alam Source Type: research

Buspirone Dose-Response on Facilitating Forelimb Functional Recovery in Cervical Spinal Cord Injured Rats
In this study, we investigated the dose-response of Buspirone treatment on reaching and grasping function in cervical cord injured rats. Seventeen adult Sprague-Dawley rats were trained to reach and grasp sugar pellets before a C4 bilateral dorsal column crush injury. After 1 week post-injury, the rats were divided into 3 groups to receive 1 of 3 different dosages of Buspirone (i.p., 1 dose/day: 1.5, n = 5; 2.5, n = 6 and 3.5 mg/kg b.w., n = 6). Forelimb reaching and grip strength test were recorded once per week, within 1 hour of Buspirone administration for 11 weeks post-injury. Different dose groups began to exhibit dif...
Source: Dose Response - March 15, 2021 Category: Drugs & Pharmacology Authors: Rakib Uddin Ahmed V Reggie Edgerton Shuai Li Yong-Ping Zheng Monzurul Alam Source Type: research

Buspirone Dose-Response on Facilitating Forelimb Functional Recovery in Cervical Spinal Cord Injured Rats
In this study, we investigated the dose-response of Buspirone treatment on reaching and grasping function in cervical cord injured rats. Seventeen adult Sprague-Dawley rats were trained to reach and grasp sugar pellets before a C4 bilateral dorsal column crush injury. After 1 week post-injury, the rats were divided into 3 groups to receive 1 of 3 different dosages of Buspirone (i.p., 1 dose/day: 1.5, n = 5; 2.5, n = 6 and 3.5 mg/kg b.w., n = 6). Forelimb reaching and grip strength test were recorded once per week, within 1 hour of Buspirone administration for 11 weeks post-injury. Different dose groups began to exhibit dif...
Source: Dose Response - March 15, 2021 Category: Drugs & Pharmacology Authors: Rakib Uddin Ahmed V Reggie Edgerton Shuai Li Yong-Ping Zheng Monzurul Alam Source Type: research

Buspirone Dose-Response on Facilitating Forelimb Functional Recovery in Cervical Spinal Cord Injured Rats
In this study, we investigated the dose-response of Buspirone treatment on reaching and grasping function in cervical cord injured rats. Seventeen adult Sprague-Dawley rats were trained to reach and grasp sugar pellets before a C4 bilateral dorsal column crush injury. After 1 week post-injury, the rats were divided into 3 groups to receive 1 of 3 different dosages of Buspirone (i.p., 1 dose/day: 1.5, n = 5; 2.5, n = 6 and 3.5 mg/kg b.w., n = 6). Forelimb reaching and grip strength test were recorded once per week, within 1 hour of Buspirone administration for 11 weeks post-injury. Different dose groups began to exhibit dif...
Source: Dose Response - March 15, 2021 Category: Drugs & Pharmacology Authors: Rakib Uddin Ahmed V Reggie Edgerton Shuai Li Yong-Ping Zheng Monzurul Alam Source Type: research