< em > Burkholderia cepacia < /em > skin-related ulceration: a case report
Br J Nurs. 2023 Nov 1;32(Sup20):S6-S10. doi: 10.12968/bjon.2023.32.Sup20.S6.ABSTRACTTreatment of infected wounds remains a major challenge for clinicians. Antimicrobial stewardship is an important pillar in wound treatment and, as the role of bacteria in wound repair is not well understood, new treatment options and products are constantly being developed to tackle local infection and biofilm. This case report describes a case of antibiotic-resistant Burkholderia cepacia skin infection and subsequent leg ulceration in an 86-year-old man during the COVID pandemic in Italy, which was successfully treated in a conservative wa...
Source: British Journal of Nursing - November 10, 2023 Category: Nursing Authors: Massimo Rivolo Erind Ruka Salvatore Piazza Source Type: research
< em > Burkholderia cepacia < /em > skin-related ulceration: a case report
Br J Nurs. 2023 Nov 1;32(Sup20):S6-S10. doi: 10.12968/bjon.2023.32.Sup20.S6.ABSTRACTTreatment of infected wounds remains a major challenge for clinicians. Antimicrobial stewardship is an important pillar in wound treatment and, as the role of bacteria in wound repair is not well understood, new treatment options and products are constantly being developed to tackle local infection and biofilm. This case report describes a case of antibiotic-resistant Burkholderia cepacia skin infection and subsequent leg ulceration in an 86-year-old man during the COVID pandemic in Italy, which was successfully treated in a conservative wa...
Source: British Journal of Nursing - November 10, 2023 Category: Nursing Authors: Massimo Rivolo Erind Ruka Salvatore Piazza Source Type: research
< em > Burkholderia cepacia < /em > skin-related ulceration: a case report
Br J Nurs. 2023 Nov 1;32(Sup20):S6-S10. doi: 10.12968/bjon.2023.32.Sup20.S6.ABSTRACTTreatment of infected wounds remains a major challenge for clinicians. Antimicrobial stewardship is an important pillar in wound treatment and, as the role of bacteria in wound repair is not well understood, new treatment options and products are constantly being developed to tackle local infection and biofilm. This case report describes a case of antibiotic-resistant Burkholderia cepacia skin infection and subsequent leg ulceration in an 86-year-old man during the COVID pandemic in Italy, which was successfully treated in a conservative wa...
Source: British Journal of Nursing - November 10, 2023 Category: Nursing Authors: Massimo Rivolo Erind Ruka Salvatore Piazza Source Type: research
Biocontrol of biofilm forming Burkholderia cepacia using a quorum quenching crude lactonase enzyme extract from a marine Chromohalobacter sp. strain D23
Arch Microbiol. 2023 Nov 8;205(12):374. doi: 10.1007/s00203-023-03712-8.ABSTRACTBiofilm plays advantageous role in Burkholderia cepacia by exerting multi-drug resistance. As quorum sensing (QS) system regulates biofilm formation and pathogenicity in B. cepacia strains, quorum quenching (QQ) may be a novel strategy to control persistent B. cepacia infections. In these regards, 120 halophilic bacteria were isolated from marine sample and tested using Chromobacterium violaceum and C. violaceum CV026-based bioassays initially, showing reduced violacein synthesis by QQ enzyme by 6 isolates. Among them, Chromohalobacter sp. D23 ...
Source: Archives of Microbiology - November 7, 2023 Category: Microbiology Authors: Dhritishree Ghosh Madhupa Seth Priyajit Mondal Subhra Kanti Mukhopadhyay Source Type: research
Biocontrol of biofilm forming Burkholderia cepacia using a quorum quenching crude lactonase enzyme extract from a marine Chromohalobacter sp. strain D23
Arch Microbiol. 2023 Nov 8;205(12):374. doi: 10.1007/s00203-023-03712-8.ABSTRACTBiofilm plays advantageous role in Burkholderia cepacia by exerting multi-drug resistance. As quorum sensing (QS) system regulates biofilm formation and pathogenicity in B. cepacia strains, quorum quenching (QQ) may be a novel strategy to control persistent B. cepacia infections. In these regards, 120 halophilic bacteria were isolated from marine sample and tested using Chromobacterium violaceum and C. violaceum CV026-based bioassays initially, showing reduced violacein synthesis by QQ enzyme by 6 isolates. Among them, Chromohalobacter sp. D23 ...
Source: Archives of Microbiology - November 7, 2023 Category: Microbiology Authors: Dhritishree Ghosh Madhupa Seth Priyajit Mondal Subhra Kanti Mukhopadhyay Source Type: research
Endophthalmitis caused by Burkholderia cepacia complex (BCC): clinical characteristics, antibiotic susceptibilities, and treatment outcomes
ConclusionsEndophthalmitis caused byB. cepacia is a rare clinical entity with generally poor visual outcomes despite prompt treatment with appropriate antibiotics. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - November 3, 2023 Category: Opthalmology Source Type: research
Hormesis of glyphosate on ferulic acid metabolism and antifungal volatile production in rice root biocontrol endophyte Burkholderia cepacia LS-044
Chemosphere. 2023 Oct 21:140511. doi: 10.1016/j.chemosphere.2023.140511. Online ahead of print.ABSTRACTGlyphosate (GP, N-phosphonomethyl glycine) is one of the most popular organophosphate herbicides widely used in agricultural practices worldwide. There have been extensive reports on the biohazard attributes and hormetic impacts of GP on plant and animal systems. However, the effects of GP on plant growth-promoting microbes and its ecological relevance remain unknown. Here, we show that GP does exert a hormetic impact on Burkholderia cepacia LS-044, a rice (Oryza sativa ssp. japonica cv. Tainung 71) root endophytic isolat...
Source: Chemosphere - October 23, 2023 Category: Chemistry Authors: Asif Hameed Duc Hai Nguyen Shih-Yao Lin Paul Stothard Poovarasan Neelakandan Li-Sen Young Chiu-Chung Young Source Type: research
Hormesis of glyphosate on ferulic acid metabolism and antifungal volatile production in rice root biocontrol endophyte Burkholderia cepacia LS-044
Chemosphere. 2023 Oct 21:140511. doi: 10.1016/j.chemosphere.2023.140511. Online ahead of print.ABSTRACTGlyphosate (GP, N-phosphonomethyl glycine) is one of the most popular organophosphate herbicides widely used in agricultural practices worldwide. There have been extensive reports on the biohazard attributes and hormetic impacts of GP on plant and animal systems. However, the effects of GP on plant growth-promoting microbes and its ecological relevance remain unknown. Here, we show that GP does exert a hormetic impact on Burkholderia cepacia LS-044, a rice (Oryza sativa ssp. japonica cv. Tainung 71) root endophytic isolat...
Source: Chemosphere - October 23, 2023 Category: Chemistry Authors: Asif Hameed Duc Hai Nguyen Shih-Yao Lin Paul Stothard Poovarasan Neelakandan Li-Sen Young Chiu-Chung Young Source Type: research
Outbreak investigation of NDM-producing Burkholderia cepacia causing neonatal sepsis in Pakistan
Future Microbiology, Ahead of Print. (Source: Future Microbiology)
Source: Future Microbiology - October 18, 2023 Category: Microbiology Authors: Alia Batool Asma Yaqoob Zahid Anwar Lovleen Tina Joshi Ramsha Batool Durreshahwar Lone Zikria Saleem Qasim Ahmed Yousef A Bin Jardn Mohammed Bourhia Muhammad Usman Qamar Source Type: research
The investigation of antibacterial properties of peptides and protein hydrolysates derived from serum of Asian water monitor ( < i > Varanus salvator < /i > )
by Jitkamol Thanasak, Sittiruk Roytrakul, Waraphan Toniti, Janthima Jaresitthikunchai, Narumon Phaonakrop, Siriwan Thaisakun, Sawanya Charoenlappanit, Rudee Surarit, Wanna Sirimanapong
It is well known that the Asian water monitors orVaranus salvator are both scavengers and predators. They can live and survive in the place that exposed to harmful microorganisms. Most people believe that they have some protected mechanisms to confront those infections. The aim of this study is to determine the antibacterial activities of crude peptides and protein hydrolysates extracted from serum of theVaranus salvator. Ten types of bacte...
Source: PLoS One - October 18, 2023 Category: Biomedical Science Authors: Jitkamol Thanasak Source Type: research
97 pH dependence of niclosamide activity as a repurposed adjuvant for treatment of Burkholderia cepacia complex lung infections
(Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - October 1, 2023 Category: Respiratory Medicine Authors: M. Romero-Gonzalez, L. Caverly, A. Brunaugh Tags: INFECTION/MICROBIOLOGY Source Type: research
3 ELD607, a novel Orai1 antagonist, reduces inflammation and clears Burkholderia cepacia complex and multidrug-resistant Pseudomonas aeruginosa from the lungs
(Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - October 1, 2023 Category: Respiratory Medicine Authors: S. Ahmad, F. Sassano, R. Tarran Tags: INFECTION/MICROBIOLOGY Source Type: research
Examining the activity of cefepime-taniborbactam against < em > Burkholderia cepacia < /em > complex and < em > Burkholderia gladioli < /em > isolated from cystic fibrosis patients in the United States
Antimicrob Agents Chemother. 2023 Sep 28:e0049823. doi: 10.1128/aac.00498-23. Online ahead of print.ABSTRACTThe novel clinical-stage β-lactam-β-lactamase inhibitor combination, cefepime-taniborbactam, demonstrates promising activity toward many Gram-negative bacteria producing class A, B, C, and/or D β-lactamases. We tested this combination against a panel of 150 Burkholderia cepacia complex (Bcc) and Burkholderia gladioli strains. The addition of taniborbactam to cefepime shifted cefepime minimum inhibitory concentrations toward the provisionally susceptible range in 59% of the isolates tested. Therefore, cefepime-tani...
Source: Antimicrobial Agents and Chemotherapy - September 28, 2023 Category: Microbiology Authors: Maria F Mojica Elise T Zeiser Scott A Becka John J LiPuma David A Six Greg Moeck Krisztina M Papp-Wallace Source Type: research
Examining the activity of cefepime-taniborbactam against < em > Burkholderia cepacia < /em > complex and < em > Burkholderia gladioli < /em > isolated from cystic fibrosis patients in the United States
Antimicrob Agents Chemother. 2023 Sep 28:e0049823. doi: 10.1128/aac.00498-23. Online ahead of print.ABSTRACTThe novel clinical-stage β-lactam-β-lactamase inhibitor combination, cefepime-taniborbactam, demonstrates promising activity toward many Gram-negative bacteria producing class A, B, C, and/or D β-lactamases. We tested this combination against a panel of 150 Burkholderia cepacia complex (Bcc) and Burkholderia gladioli strains. The addition of taniborbactam to cefepime shifted cefepime minimum inhibitory concentrations toward the provisionally susceptible range in 59% of the isolates tested. Therefore, cefepime-tani...
Source: Antimicrobial Agents and Chemotherapy - September 28, 2023 Category: Microbiology Authors: Maria F Mojica Elise T Zeiser Scott A Becka John J LiPuma David A Six Greg Moeck Krisztina M Papp-Wallace Source Type: research
Examining the activity of cefepime-taniborbactam against < em > Burkholderia cepacia < /em > complex and < em > Burkholderia gladioli < /em > isolated from cystic fibrosis patients in the United States
Antimicrob Agents Chemother. 2023 Sep 28:e0049823. doi: 10.1128/aac.00498-23. Online ahead of print.ABSTRACTThe novel clinical-stage β-lactam-β-lactamase inhibitor combination, cefepime-taniborbactam, demonstrates promising activity toward many Gram-negative bacteria producing class A, B, C, and/or D β-lactamases. We tested this combination against a panel of 150 Burkholderia cepacia complex (Bcc) and Burkholderia gladioli strains. The addition of taniborbactam to cefepime shifted cefepime minimum inhibitory concentrations toward the provisionally susceptible range in 59% of the isolates tested. Therefore, cefepime-tani...
Source: Antimicrobial Agents and Chemotherapy - September 28, 2023 Category: Microbiology Authors: Maria F Mojica Elise T Zeiser Scott A Becka John J LiPuma David A Six Greg Moeck Krisztina M Papp-Wallace Source Type: research
