Heterologous Expression and Function of Cholesterol Oxidase: A Review
Protein Pept Lett. 2023 May 25. doi: 10.2174/0929866530666230525162545. Online ahead of print.ABSTRACTCholesterol was first found in gallstones as an animal sterol; hence it is called cholesterol. Cholesterol oxidase is the chief enzyme in the process of cholesterol degradation. Its role is obtained by the coenzyme FAD, which catalyzes the isomerization and oxidation of cholesterol to produce cholesteric 4-ene-3-ketone and hydrogen peroxide at the same time. Recently, a great advance has been made in the discovery of the structure and function of cholesterol oxidase, and it has proven added value in clinical discovery, med...
Source: Protein and Peptide Letters - May 26, 2023 Category: Biochemistry Authors: Haoran Cui Mohamad Hesam Shahrajabian Yue Kuang Haiyan Zhang Wenli Sun Source Type: research
Antimicrobial resistance patterns of Gram-negative bacteria in an Iranian referral pediatric hospital: A present danger of New Delhi metallo- β-lactamase
CONCLUSION: Our findings suggest the emergence of NDM-producing strains in our hospital, and bla NDM was the most frequently detected carbapenemase gene in MBL-producing P. aeruginosa, K. pneumoniae, and Klebsiella spp. Since such bacteria can easily spread among patients in the hospital, a strong infection control and prevention plan is highly recommended.PMID:37106518 | DOI:10.2174/1871526523666230418114213 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - April 28, 2023 Category: Infectious Diseases Authors: Shima Mahmoudi Babak Pourakbari Maryam Rostamyan Hojatollah Raji Reihaneh Hosseinpour Sadeghi Setareh Mamishi Source Type: research
Antimicrobial resistance patterns of Gram-negative bacteria in an Iranian referral pediatric hospital: A present danger of New Delhi metallo- β-lactamase
CONCLUSION: Our findings suggest the emergence of NDM-producing strains in our hospital, and bla NDM was the most frequently detected carbapenemase gene in MBL-producing P. aeruginosa, K. pneumoniae, and Klebsiella spp. Since such bacteria can easily spread among patients in the hospital, a strong infection control and prevention plan is highly recommended.PMID:37106518 | DOI:10.2174/1871526523666230418114213 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - April 28, 2023 Category: Infectious Diseases Authors: Shima Mahmoudi Babak Pourakbari Maryam Rostamyan Hojatollah Raji Reihaneh Hosseinpour Sadeghi Setareh Mamishi Source Type: research
Antimicrobial resistance patterns of Gram-negative bacteria in an Iranian referral pediatric hospital: A present danger of New Delhi metallo- β-lactamase
CONCLUSION: Our findings suggest the emergence of NDM-producing strains in our hospital, and bla NDM was the most frequently detected carbapenemase gene in MBL-producing P. aeruginosa, K. pneumoniae, and Klebsiella spp. Since such bacteria can easily spread among patients in the hospital, a strong infection control and prevention plan is highly recommended.PMID:37106518 | DOI:10.2174/1871526523666230418114213 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - April 28, 2023 Category: Infectious Diseases Authors: Shima Mahmoudi Babak Pourakbari Maryam Rostamyan Hojatollah Raji Reihaneh Hosseinpour Sadeghi Setareh Mamishi Source Type: research
Antimicrobial resistance patterns of Gram-negative bacteria in an Iranian referral pediatric hospital: A present danger of New Delhi metallo- β-lactamase
CONCLUSION: Our findings suggest the emergence of NDM-producing strains in our hospital, and bla NDM was the most frequently detected carbapenemase gene in MBL-producing P. aeruginosa, K. pneumoniae, and Klebsiella spp. Since such bacteria can easily spread among patients in the hospital, a strong infection control and prevention plan is highly recommended.PMID:37106518 | DOI:10.2174/1871526523666230418114213 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - April 28, 2023 Category: Infectious Diseases Authors: Shima Mahmoudi Babak Pourakbari Maryam Rostamyan Hojatollah Raji Reihaneh Hosseinpour Sadeghi Setareh Mamishi Source Type: research
Identification of Burkholderia cenocepacia non-coding RNAs expressed during Caenorhabditis elegans infection
Appl Microbiol Biotechnol. 2023 Apr 25. doi: 10.1007/s00253-023-12530-3. Online ahead of print.ABSTRACTSmall non-coding RNAs (sRNAs) are key regulators of post-transcriptional gene expression in bacteria. Despite the identification of hundreds of bacterial sRNAs, their roles on bacterial physiology and virulence remain largely unknown, as is the case of bacteria of the Burkholderia cepacia complex (Bcc). Bcc is a group of opportunistic pathogens with relatively large genomes that can cause lethal lung infections amongst cystic fibrosis (CF) patients. To characterise sRNAs expressed by Bcc bacteria when infecting a host, th...
Source: Applied Microbiology and Biotechnology - April 25, 2023 Category: Microbiology Authors: Tiago Pita Joana R Feliciano Jorge H Leit ão Source Type: research
Identification of Burkholderia cenocepacia non-coding RNAs expressed during Caenorhabditis elegans infection
Appl Microbiol Biotechnol. 2023 Apr 25. doi: 10.1007/s00253-023-12530-3. Online ahead of print.ABSTRACTSmall non-coding RNAs (sRNAs) are key regulators of post-transcriptional gene expression in bacteria. Despite the identification of hundreds of bacterial sRNAs, their roles on bacterial physiology and virulence remain largely unknown, as is the case of bacteria of the Burkholderia cepacia complex (Bcc). Bcc is a group of opportunistic pathogens with relatively large genomes that can cause lethal lung infections amongst cystic fibrosis (CF) patients. To characterise sRNAs expressed by Bcc bacteria when infecting a host, th...
Source: Applied Microbiology and Biotechnology - April 25, 2023 Category: Microbiology Authors: Tiago Pita Joana R Feliciano Jorge H Leit ão Source Type: research
Prevalence of < em > Burkholderia cepacia < /em > recovered from clinical specimens in the Zainoel Abidin general hospital, Banda Aceh, Indonesia
CONCLUSION: Culture examination of clinical specimens is not required for confirmed infections, despite being essential for appropriate antibiotic treatment. Implementing surveillance programs and judicious use of antibiotics can prevent bacterial transmission.PMID:37069904 | PMC:PMC10105269 | DOI:10.18502/ijm.v15i1.11916 (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - April 18, 2023 Category: Microbiology Authors: Suhartono Suhartono Wilda Mahdani Nyak Naiza Muzayanna Source Type: research
