Real-world effectiveness of fingolimod in patients with multiple sclerosis in Bulgaria
CONCLUSIONS: Quality of life scores and the depression level are improved in RRMS patients treated with fingolimod over 2 years in real-life setting.PMID:38018696 | DOI:10.33588/rn.77s04.2023213 (Source: Revista de Neurologia)
Source: Revista de Neurologia - November 29, 2023 Category: Neurology Authors: I Milanov S Ivanova I Tournev T Chamova A Kaprelyan G Slavov V Chervenkov K Kipriyanovska Source Type: research

Real-world effectiveness of fingolimod in patients with multiple sclerosis in Bulgaria
CONCLUSIONS: Quality of life scores and the depression level are improved in RRMS patients treated with fingolimod over 2 years in real-life setting.PMID:38018696 | DOI:10.33588/rn.77s04.2023213 (Source: Revista de Neurologia)
Source: Revista de Neurologia - November 29, 2023 Category: Neurology Authors: I Milanov S Ivanova I Tournev T Chamova A Kaprelyan G Slavov V Chervenkov K Kipriyanovska Source Type: research

Health Status, Type of Contract and Labour Force Participation
ConclusionBoth poor health and temporary contracts were associated with lower LFP. The magnitude of these associations varied among countries. Worker ’s health status differed by type of contract in Bulgaria, Hungary, Finland and Serbia. (Source: The Journal of Primary Prevention)
Source: The Journal of Primary Prevention - November 28, 2023 Category: Sleep Medicine Source Type: research

Poaching and illegal trade of Danube sturgeons
Curr Biol. 2023 Nov 20;33(22):R1184-R1185. doi: 10.1016/j.cub.2023.09.067.ABSTRACTA market study on sturgeon products in the Lower Danube countries (Bulgaria, Romania, Serbia and Ukraine) resulted in a total of 149 samples of caviar and meat, which we subjected to genetic-isotope analyses. The samples comprised 31 samples (21%) of illegal wild-caught origin, 17 samples (11.4%) sold in violation of CITES and EU regulations, and 47 cases (32%) of consumer deception. Although poaching and illegal wildlife trade are often considered a problem in developing countries, these findings bear evidence that a high ratio of poached st...
Source: Current Biology - November 21, 2023 Category: Biology Authors: Arne Ludwig Jutta Jahrl Leonardo Congiu Joern Gessner Thomas Friedrich Dietmar Lieckfeldt Zuogang Peng Markus Boner Source Type: research

Poaching and illegal trade of Danube sturgeons
Curr Biol. 2023 Nov 20;33(22):R1184-R1185. doi: 10.1016/j.cub.2023.09.067.ABSTRACTA market study on sturgeon products in the Lower Danube countries (Bulgaria, Romania, Serbia and Ukraine) resulted in a total of 149 samples of caviar and meat, which we subjected to genetic-isotope analyses. The samples comprised 31 samples (21%) of illegal wild-caught origin, 17 samples (11.4%) sold in violation of CITES and EU regulations, and 47 cases (32%) of consumer deception. Although poaching and illegal wildlife trade are often considered a problem in developing countries, these findings bear evidence that a high ratio of poached st...
Source: Current Biology - November 21, 2023 Category: Biology Authors: Arne Ludwig Jutta Jahrl Leonardo Congiu Joern Gessner Thomas Friedrich Dietmar Lieckfeldt Zuogang Peng Markus Boner Source Type: research

Assessing the Readability of Online Health Information for Colonoscopy — Analysis of Articles in 22 European Languages
This study aimed to evaluate online health information on colonoscopy, focusing on quantity and comprehensibility of internet resources dedicated to the colonoscopy. This information could be used by European Union (EU) colorectal cancer (CRC) screening providers to address patient ’s unfilled educational needs, fear of colonoscopy, and other barriers that deter from CRC screening. The term “colonoscopy” translated into 22 official EU languages was searched using the Google search engine. For each translation, generated list of websites was assessed with Google Translate . The first 50 websites in each language were ...
Source: Journal of Cancer Education - November 17, 2023 Category: Cancer & Oncology Source Type: research

Sign of APOBEC editing, purifying selection, frameshift, and in-frame nonsense mutations in the microevolution of lumpy skin disease virus
The lumpy skin disease virus (LSDV), which mostly affects ruminants and causes huge-economic loss, was endemic in Africa, caused outbreaks in the Middle East, and was recently detected in Russia, Serbia, Greece, Bulgaria, Kazakhstan, China, Taiwan, Vietnam, Thailand, and India. However, the role of evolutionary drivers such as codon selection, negative/purifying selection, APOBEC editing, and genetic variations such as frameshift and in-frame nonsense mutations in the LSDVs, which cause outbreaks in cattle in various countries, are still largely unknown. In the present study, a frameshift mutation in LSDV035, LSDV019, LSDV...
Source: Frontiers in Microbiology - November 14, 2023 Category: Microbiology Source Type: research

First multi-center retrospective study assessed the compliance with and persistence of biological therapies in Bulgarian population with rheumatoid arthritis
The objective of this study was to estimate the compliance to and persistence of biologic disease-modifying anti-rheumatic drugs (bDMARDs) among the Bulgarian population with RA. This retrospective observational cohort study included 179 patients, who were tracked over a 36-mon th period. During baseline and subsequent follow-up visits (at months 6, 12, 24, and 36), we monitored the disease activity, side effects, medication tolerability and effectiveness, compliance, and persistence to the prescribed biologic agent. The compliance with bDMARDs among Bulgarian patients wit h RA was 85.5% in the first year, 76.0% in the sec...
Source: Rheumatology International - November 9, 2023 Category: Rheumatology Source Type: research

Molecular epidemiology and antimicrobial resistance of Haemophilus influenzae isolates from otitis media in Bulgaria
Acta Microbiol Immunol Hung. 2023 Nov 8. doi: 10.1556/030.2023.02126. Online ahead of print.ABSTRACTHaemophilus influenzae is one of the main bacteria responsible for otitis media (OM) among children worldwide. We aimed to estimate the distribution of encapsulated and non-capsulated variants (NTHi), biotypes, antibiotic susceptibility, and molecular epidemiology of H. influenzae isolates recovered from pediatric OM cases in Bulgaria.Capsule detection was done by PCR for bexB gene, absent in NTHi. All encapsulated strains were subjected to PCR serotyping. MIC susceptibility testing was performed according to the criteria of...
Source: Acta Microbiologica et Immunologica Hungarica - November 8, 2023 Category: Microbiology Authors: Alexandra Sashova Alexandrova Ivo Nikolaev Sirakov Lena Petrova Setchanova Kalina Ionkova Mihova Daniela Rosenova Pencheva Raina Tsvetanova Gergova Source Type: research

Molecular epidemiology and antimicrobial resistance of Haemophilus influenzae isolates from otitis media in Bulgaria
Acta Microbiol Immunol Hung. 2023 Nov 8. doi: 10.1556/030.2023.02126. Online ahead of print.ABSTRACTHaemophilus influenzae is one of the main bacteria responsible for otitis media (OM) among children worldwide. We aimed to estimate the distribution of encapsulated and non-capsulated variants (NTHi), biotypes, antibiotic susceptibility, and molecular epidemiology of H. influenzae isolates recovered from pediatric OM cases in Bulgaria.Capsule detection was done by PCR for bexB gene, absent in NTHi. All encapsulated strains were subjected to PCR serotyping. MIC susceptibility testing was performed according to the criteria of...
Source: Acta Microbiologica et Immunologica Hungarica - November 8, 2023 Category: Microbiology Authors: Alexandra Sashova Alexandrova Ivo Nikolaev Sirakov Lena Petrova Setchanova Kalina Ionkova Mihova Daniela Rosenova Pencheva Raina Tsvetanova Gergova Source Type: research

Molecular epidemiology and antimicrobial resistance of Haemophilus influenzae isolates from otitis media in Bulgaria
Acta Microbiol Immunol Hung. 2023 Nov 8. doi: 10.1556/030.2023.02126. Online ahead of print.ABSTRACTHaemophilus influenzae is one of the main bacteria responsible for otitis media (OM) among children worldwide. We aimed to estimate the distribution of encapsulated and non-capsulated variants (NTHi), biotypes, antibiotic susceptibility, and molecular epidemiology of H. influenzae isolates recovered from pediatric OM cases in Bulgaria.Capsule detection was done by PCR for bexB gene, absent in NTHi. All encapsulated strains were subjected to PCR serotyping. MIC susceptibility testing was performed according to the criteria of...
Source: Acta Microbiologica et Immunologica Hungarica - November 8, 2023 Category: Microbiology Authors: Alexandra Sashova Alexandrova Ivo Nikolaev Sirakov Lena Petrova Setchanova Kalina Ionkova Mihova Daniela Rosenova Pencheva Raina Tsvetanova Gergova Source Type: research

Molecular epidemiology and antimicrobial resistance of Haemophilus influenzae isolates from otitis media in Bulgaria
Acta Microbiol Immunol Hung. 2023 Nov 8. doi: 10.1556/030.2023.02126. Online ahead of print.ABSTRACTHaemophilus influenzae is one of the main bacteria responsible for otitis media (OM) among children worldwide. We aimed to estimate the distribution of encapsulated and non-capsulated variants (NTHi), biotypes, antibiotic susceptibility, and molecular epidemiology of H. influenzae isolates recovered from pediatric OM cases in Bulgaria.Capsule detection was done by PCR for bexB gene, absent in NTHi. All encapsulated strains were subjected to PCR serotyping. MIC susceptibility testing was performed according to the criteria of...
Source: Acta Microbiologica et Immunologica Hungarica - November 8, 2023 Category: Microbiology Authors: Alexandra Sashova Alexandrova Ivo Nikolaev Sirakov Lena Petrova Setchanova Kalina Ionkova Mihova Daniela Rosenova Pencheva Raina Tsvetanova Gergova Source Type: research

Molecular epidemiology and antimicrobial resistance of Haemophilus influenzae isolates from otitis media in Bulgaria
Acta Microbiol Immunol Hung. 2023 Nov 8. doi: 10.1556/030.2023.02126. Online ahead of print.ABSTRACTHaemophilus influenzae is one of the main bacteria responsible for otitis media (OM) among children worldwide. We aimed to estimate the distribution of encapsulated and non-capsulated variants (NTHi), biotypes, antibiotic susceptibility, and molecular epidemiology of H. influenzae isolates recovered from pediatric OM cases in Bulgaria.Capsule detection was done by PCR for bexB gene, absent in NTHi. All encapsulated strains were subjected to PCR serotyping. MIC susceptibility testing was performed according to the criteria of...
Source: Acta Microbiologica et Immunologica Hungarica - November 8, 2023 Category: Microbiology Authors: Alexandra Sashova Alexandrova Ivo Nikolaev Sirakov Lena Petrova Setchanova Kalina Ionkova Mihova Daniela Rosenova Pencheva Raina Tsvetanova Gergova Source Type: research

Molecular epidemiology and antimicrobial resistance of Haemophilus influenzae isolates from otitis media in Bulgaria
Acta Microbiol Immunol Hung. 2023 Nov 8. doi: 10.1556/030.2023.02126. Online ahead of print.ABSTRACTHaemophilus influenzae is one of the main bacteria responsible for otitis media (OM) among children worldwide. We aimed to estimate the distribution of encapsulated and non-capsulated variants (NTHi), biotypes, antibiotic susceptibility, and molecular epidemiology of H. influenzae isolates recovered from pediatric OM cases in Bulgaria.Capsule detection was done by PCR for bexB gene, absent in NTHi. All encapsulated strains were subjected to PCR serotyping. MIC susceptibility testing was performed according to the criteria of...
Source: Acta Microbiologica et Immunologica Hungarica - November 8, 2023 Category: Microbiology Authors: Alexandra Sashova Alexandrova Ivo Nikolaev Sirakov Lena Petrova Setchanova Kalina Ionkova Mihova Daniela Rosenova Pencheva Raina Tsvetanova Gergova Source Type: research