Difficult-to-treat chronic rhinosinusitis-when the standard treatment is not effective and biologics are not available
CONCLUSION: To accurately assess the efficacy of second-line therapies for treatment of difficult-to-treat CRS within an endotype-specific framework, additional controlled clinical trials are needed that take into account the heterogeneity of CRS endotypes.PMID:38472346 | DOI:10.1007/s00106-024-01443-w (Source: HNO)
Source: HNO - March 13, 2024 Category: ENT & OMF Authors: Robert B öscke Source Type: research
Trends in mortality related to venous thromboembolism in the European Union, 2012 –2020
AbstractWe sought to assess the sex- and age-specific trends in venous thromboembolism (VTE) mortality in the 27 European Union Member States (EU-27) between years 2012 and 2020. Data on cause-specific deaths and population numbers by sex for each country of the EU-27 were retrieved through the publicly available European Statistical Office (EUROSTAT) dataset for the years 2012 –2020. VTE-related deaths were ascertained when ICD-10 codes I26, I80, and I82.9 were listed as the primary cause of death in the medical death certificate. To calculate annual trends, we assessed the average annual percent change (AAPC) with rela...
Source: Internal and Emergency Medicine - March 6, 2024 Category: Emergency Medicine Source Type: research
Eosinophils in otorhinolaryngology: friend or foe?
This article summarizes the essential aspects of current knowledge about eosinophils, classifies eosinophilia in terms of the dimensions healthy or harmful reaction, takes a specific look at eosinophils in the field of otorhinolaryngology, and gives recommendations for diagnostic workup and therapeutic intervention in case of proven eosinophilia, particularly as an adverse drug reaction. The thoughts are inspired by communications at the 29th Congress of the European Rhinologic Society in Sofia, Bulgaria, 2023.PMID:38436705 | DOI:10.1007/s00106-024-01442-x (Source: HNO)
Source: HNO - March 4, 2024 Category: ENT & OMF Authors: Martin Laudien Source Type: research
IDF23-0538 Bulgarian community pharmacists' knowledge towards diabetes mellitus management: results of a pilot survey
(Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 1, 2024 Category: Endocrinology Authors: R. Staynova, E. Gavazova, V. Yanachkova, D. Kafalova Tags: Other Complications Source Type: research
Readability of Patient Electronic Materials for Atopic Dermatitis in 23 Languages: Analysis and Implications for Dermatologists
ConclusionsAlthough there was an abundance of online articles related to AD, the readability of the available information was low. As online health information has become essential in making shared decisions between patients and physicians, an improvement in AD-related materials is needed. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - February 24, 2024 Category: Dermatology Source Type: research
Local flap reconstruction techniques after frontal sinus drainage type II and III according to Draf
CONCLUSION: The results and achieved opening areas in contemporary Draf III surgeries are significantly improved and larger compared to the early stages of these procedures. A multitude of published studies consistently demonstrate that outcomes are markedly improved with mucosal coverage. Depending on the prevailing anatomy, mucosal conditions, and the extent of the surgical intervention, the most suitable technique should be selected. Therefore, proficiency in various methods is crucial. The use of a flap technique (free, pedicled, or combinations thereof) should be defined as the standard when performing extended fronta...
Source: HNO - February 22, 2024 Category: ENT & OMF Authors: F Sommer Rainer K Weber Source Type: research
